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UBE1C (UBA3) (NM_198197) Human Untagged Clone
CAT＃: SC127005
UBE1C (untagged)-Human ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 3
CNY 3,656.00
CNY 7,410.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | UBA3, hUba3, MGC22384, DKFZp566J164 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127005 sequence for NM_198197 edited (data generated by NextGen Sequencing)
ATGGACACTATAGATGTTTCCAATCTAAATAGGCAGTTTTTATTTAGGCCTAAAGATATT GGAAGACCTAAGGCTGAAGTTGCTGCAGAATTTCTAAATGACAGAGTTCCTAATTGCAAT GTAGTTCCACATTTCAACAAGATTCAAGATTTTAACGACACTTTCTATCGACAATTTCAT ATTATTGTATGTGGACTGGACTCTATCATCGCCAGAAGATGGATAAATGGCATGCTGATA TCTCTTCTAAATTATGAAGATGGTGTCTTAGATCCAAGCTCCATTGTCCCTTTGATAGAT GGGGGGACAGAAGGTTTTAAAGGAAATGCCCGGGTGATTCTGCCTGGAATGACTGCTTGT ATCGAATGCACGCTGGAACTTTATCCACCACAGGTTAATTTTCCCATGTGCACCATTGCA TCTATGCCCAGGCTACCAGAACACTGTATTGAGTATGTAAGGATGTTGCAGTGGCCTAAG GAGCAGCCTTTTGGAGAAGGGGTTCCATTAGATGGAGATGATCCTGAACATATACAATGG ATTTTCCAAAAATCCCTAGAGAGAGCATCACAATATAATATTAGGGGTGTTACGTATAGG CTCACTCAAGGGGTAGTAAAAAGAATCATTCCTGCAGTAGCTTCCACAAATGCAGTCATT GCAGCTGTGTGTGCCACTGAGGTTTTTAAAATAGCCACAAGTGCATACATTCCCTTGAAT AATTACTTGGTGTTTAATGATGTAGATGGGCTGTATACATACACATTTGAAGCAGAAAGA AAGGAAAACTGCCCAGCTTGTAGCCAGCTTCCTCAAAATATTCAGTTTTCTCCATCAGCT AAACTACAGGAGGTTTTGGATTATCTAACCAATAGTGCTTCTCTGCAAATGAAATCTCCA GCCATCACAGCCACCCTAGAGGGAAAAAATAGAACACTTTACTTACAGTCGGTAACCTCT ATTGAAGAACGAACAAGGCCAAATCTCTCCAAAACATTGAAAGAATTGGGGCTTGTTGAT GGACAAGAACTGGCGGTTGCTGATGTCACCACCCCACAGACTGTACTATTCAAACTTCAT TTTACTTCTTAA Clone variation with respect to NM_198197.1 >OriGene 5' read for NM_198197 unedited
TATTTTCCCGCCCGTTGCCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC GAATTCGGCACGAGGGGATGGCGAGGAGCCGGTAGAAGAAAAGAAGGAGAATAGAGGAGC TGCTGGCTGAGAAAATGGCTGTTGATGGTGGGTGTGGGGACACTGGAGACTGGGAAGGTC GCTGGAACCATGTAAAGAAGTTCCTCGAGCGATCTGGACCCTTCACACACCCTGATTTCG AACCGAGCACTGAATCTCTCCAGTTCTTGTTAGATACATGTAAAGTTCTAGTCATTGGAG CTGGCGGCTTAGGATGTGAGCTCCTGAAAAATCTGGCCTTGTCTGGTTTTAGACAGATTC ATGTTATAGATATGGACACTATAGATGTTTCCAATCTAAATAGGCAGTTTTTATTTAGGC CTAAAGATATTGGAAGACCTAAGGCTGAAGTTGCTGCAGAATTTCTAAATGACAGAGTTC CTAATTGCAATGTAGTTCCACATTTCAACAAGATTCAAGATTTTAACGACACTTTCTATC GACAATTTCATATTATTGTATGTGGACTGGACTCTATCATCGCCAGAAGATGGATAAATG GCATGCTGATATCTCTTCTAAATATGAAGAGGTGTCTTAGATCCAGCTCCATGTCCCTTT GATAGATGGGGGACAGAAGGNTTTAAAGGAATGCCCGGNTGATTCTGCCTGGAAGACTGC CTGTATACAATGCACCCTGAAACTTATCCCCACAGGTTAATTTTCCATGTGCCCATTGCA CTTATGCCCAGCTACCCAAAACCTNATTGAGTATGTAAGATGTTGCAGGGCCCTAAGGAC CGCCTTTGAGAAGGGGTTCATTAAAAGGAAC >OriGene 3' read for NM_198197 unedited
CCCCCCAATAGTTGTCCGCGGCCCATTCTANGATCNGTTTTTTTTTTTTTTTTTTACACA ATATATGATTTTATTAATAAATAGTGCAAAAGCATCAGTGATAACTGTTTGAACATTAAA TTTTTTAAACAGCCATGTCTTGGCATTAGTTAATATTGTGCATATTGGCCTCTATGGCAC TACAAGTAAACAGATGAAAATATTGCCCATTTTCATGCTCAGTTATTCAGCTATAACACC ATTTACAAATCATTATGAACAAGATAAATTCTGCAATAATATTCATTTGGATGGCCACAA TTAAATGAGTGTTATATCAAGAAATAGCCTATGTTCAATATACTCCAGATGTCAGATTGT AAAATGTAATGTTATTTAAAACTTAATTCTTTATTTTCCTTAAAGGGACACCTTTTGTGT ATTTGGGTACTCAAATGAAAACTTAGGAATGCATTCTTTGACCATAATAACAAAATTCAC ACAAAAGAGGTTGTATGCTTCCTCCTCTAAAAGAAGCAATACATTTGCTCATAATCTCTC TCTCCAGGTATCATTTCTCATATTATTAATGAAAATGCTTACAAGCACCAACACCAAAAT TCTGTCTTCAAGGGAAGGTTACAAAGTTAAAAAAGAGTGGGTCATTATATAAAAAAAGAC AAATCGTGGCAACACTATTGCTAAAAATGACATCTGATTTAACTTCTTAGCATCCACAAA GTATATTATTTTCCATGAGTTTTTCTATTATGTGGGAGATTTTCCCTTAAGAAGTAAAAT GAAGTTTGCATAGTACAGTCTGTGGGGTGAGGACATCAGCAACCGCAGTTTCTGTCCACA ACAACCCCAAATTTTTTAATGTTTTGGAGAGATTGCGCCCTGTTCCGCTCTTCAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_198197 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_198197.1, NP_937840.1 |
| RefSeq Size | 2015 bp |
| RefSeq ORF | 1092 bp |
| Locus ID | 9039 |
| Protein Pathways | Ubiquitin mediated proteolysis |
| Gene Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) lacks an exon in the 5' region and uses a downstream start codon, as compared to variant 1. The encoded isoform (3) has a shorter N-terminus, as compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224294 | UBE1C (Myc-DDK-tagged)-Human ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 3 |
CNY 3,656.00 |
|
| RC224294L3 | Lenti ORF clone of Human ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224294L4 | Lenti ORF clone of Human ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG224294 | UBE1C (tGFP-tagged) - Human ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) (UBE1C), transcript variant 3 |
CNY 4,370.00 |
