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MED13 (NM_005121) Human Untagged Clone
CAT＃: SC126930
MED13 (untagged)-Human mediator complex subunit 13 (MED13)
CNY 14,360.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARC250; DRIP250; HSPC221; MRD61; THRAP1; TRAP240 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126930 sequence for NM_005121 edited (data generated by NextGen Sequencing)
ATGAGTGCCTCCTTCGTGCCGAACGGGGCCAGCCTGGAAGATTGTCACTGTAACCTCTTC TGCCTGGCTGACTTGACAGGAATTAAGTGGAAAAAATATGTATGGCAAGGCCCAACTTCT GCCCCTATTCTGTTTCCTGTGACAGAAGAAGACCCCATTTTGAGCAGTTTTAGTCGCTGC CTTAAGGCAGATGTACTTGGTGTTTGGCGGCGAGATCAAAGACCTGGAAGAAGAGAATTG TGGATATTTTGGTGGGGTGAAGACCCCAGTTTTGCTGACCTTATTCACCATGACTTATCA GAAGAAGAAGATGGAGTGTGGGAGAATGGACTTTCCTATGAATGCCGTACTCTGCTTTTC AAAGCAGTTCACAATCTATTGGAACGGTGTTTAATGAACAGGAATTTTGTACGTATTGGC AAGTGGTTTGTAAAGCCTTATGAAAAAGATGAAAAACCTATAAATAAAAGTGAACACTTG TCCTGCTCCTTCACCTTTTTCTTGCATGGAGACAGCAATGTTTGTACCAGTGTGGAAATT AACCAACATCAACCTGTATACCTTCTCAGTGAAGAGCATATCACCCTTGCTCAACAGTCT AATAGCCCATTTCAAGTTATCTTATGCCCATTTGGACTAAATGGCACTCTCACAGGACAG GCATTCAAGATGTCTGATTCAGCTACAAAAAAATTAATTGGTGAATGGAAACAGTTCTAT CCTATCTCATGTTGCTTGAAGGAGATGTCTGAAGAAAAACAGGAAGATATGGATTGGGAA GATGATTCTTTAGCTGCAGTAGAAGTTCTTGTTGCTGGTGTCCGAATGATCTACCCAGCA TGCTTTGTTCTAGTCCCTCAGTCAGACATTCCTACTCCTAGCCCTGTGGGATCCACTCAC TGTTCATCTTCTTGCTTGGGTGTCCACCAAGTGCCTGCTTCCACAAGAGATCCTGCTATG TCTTCGGTTACGCTTACACCACCTACGTCTCCTGAGGAAGTCCAAACAGTTGATCCTCAG TCTGTCCAGAAGTGGGTCAAATTTTCTTCAGTATCTGATGGCTTCAACTCCGATAGTACT AGCCACCATGGTGGGAAAATACCCAGAAAATTAGCAAATCATGTGGTGGATAGAGTTTGG CAAGAATGCAATATGAACAGAGCACAGAACAAGAGGAAGTATTCTGCTTCATCAGGTGGT CTATGCGAAGAAGCGACAGCTGCTAAAGTGGCATCCTGGGATTTTGTTGAAGCCACACAA AGAACAAATTGCAGTTGTTTGAGGCACAAAAATCTCAAGTCAAGAAATGCTGGACAACAA GGACAGGCACCATCTTTAGGTCAGCAACAACAAATACTTCCTAAGCACAAGACCAATGAG AAGCAAGAAAAGAGTGAAAAGCCACAGAAACGCCCCTTGACTCCTTTTCACCATCGTGTG TCTGTTAGTGATGATGTTGGCATGGACGCAGATTCAGCCAGCCAAAGACTTGTGATCTCT GCTCCAGACAGTCAAGTGAGATTTTCAAATATCCGAACTAATGATGTAGCAAAGACTCCT CAGATGCATGGCACCGAAATGGCAAATTCACCTCAACCACCCCCACTTAGTCCTCACCCT TGTGATGTGGTTGATGAAGGAGTGACTAAAACACCTTCAACTCCTCAGAGTCAACATTTT TATCAAATGCCAACACCAGATCCCTTGGTTCCTTCTAAACCAATGGAAGATAGGATAGAC AGTTTGTCCCAGTCTTTCCCACCTCAATATCAGGAAGCTGTAGAACCTACAGTATATGTT GGTACAGCAGTAAACTTGGAAGAAGATGAAGCCAATATAGCCTGGAAGTATTACAAGTTC CCAAAGAAAAAAGATGTAGAGTTTTTACCACCTCAACTTCCAAGTGATAAATTCAAGGAT GATCCAGTTGGACCTTTTGGACAGGAAAGTGTAACATCAGTTACAGAGTTAATGGTGCAA TGTAAGAAACCTTTAAAAGTTTCTGATGAATTAGTGCAGCAATATCAAATTAAAAACCAG TGTCTTTCAGCAATAGCATCTGATGCAGAACAAGAACCTAAAATTGATCCATATGCATTT GTTGAAGGAGATGAGGAATTCCTTTTTCCTGATAAAAAAGATAGACAAAATAGTGAGAGA GAAGCTGAAAAAAAACACAAGGTAGAAGATGGGACATCTAGTGTAACAGTGTTATCACAT GAAGAAGATGCTATGTCATTATTTAGTCCCTCTATCAAGCAAGATGCTCCACGCCCTACT AGTCATGCCCGTCCTCCATCAACAAGTTTGATTTATGACTCAGACCTGGCTGTCTCTTAT ACTGACCTTGATAATCTCTTCAATTCTGATGAAGATGAACTAACACCTGGATCTAAAAAA TCAGCAAATGGATCAGATGATAAAGCCAGCTGCAAGGAATCAAAGACAGGAAATCTGGAC CCGTTATCTTGCATAAGCACTGCAGATCTTCATAAAATGTATCCTACACCACCATCATTG GAACAACATATTATGGGATTTTCCCCAATGAATATGAATAATAAAGAATATGGTAGTATG GATACAACACCTGGAGGAACTGTTCTAGAAGGAAATAGTTCTAGTATAGGAGCGCAGTTC AAAATTGAGGTTGATGAGGGATTCTGTAGCCCCAAACCTTCTGAAATTAAAGATTTTTCT TATGTCTATAAGCCTGAAAATTGTCAAATTCTAGTGGGATGTTCCATGTTTGCACCTCTA AAAACTCTACCAAGCCAATATCTGCCCCCTATCAAATTGCCAGAAGAGTGTATTTACCGT CAGAGTTGGACTGTTGGAAAATTGGAATTGCTTTCTTCAGGGCCTTCAATGCCATTCATC AAAGAGGGTGATGGAAGTAATATGGATCAAGAATATGGCACTGCTTATACACCTCAAACT CATACTTCTTTTGGGATGCCTCCTAGCAGTGCACCTCCTAGTAACAGCGGAGCAGGAATT CTTCCTTCTCCATCCACCCCTCGGTTTCCAACTCCAAGGACTCCAAGGACTCCTCGGACT CCTCGTGGAGCTGGTGGACCTGCTAGTGCTCAAGGTTCAGTCAAATATGAAAATTCAGAC TTGTATTCACCAGCTTCTACCCCATCTACATGCAGACCCCTTAATTCTGTTGAACCTGCA ACTGTCCCTTCCATCCCTGAAGCACACAGTCTTTATGTAAACCTCATCCTTTCAGAATCA GTTATGAATTTGTTTAAAGACTGTAACTTTGATAGTTGTTGCATCTGTGTTTGCAACATG AACATCAAGGGTGCCGATGTTGGAGTTTACATTCCAGATCCAACGCAGGAAGCACAATAT AGGTGTACCTGTGGCTTCAGTGCTGTCATGAACAGAAAATTTGGAAACAATTCAGGATTA TTTCTTGAAGATGAACTAGATATCATAGGACGCAATACAGACTGTGGCAAAGAAGCAGAA AAACGTTTTGAAGCTCTCAGGGCTACCTCTGCTGAACATGTTAATGGAGGACTAAAGGAA TCTGAAAAATTATCTGATGATTTGATATTATTGCTACAAGATCAGTGCACTAATTTATTT TCACCCTTTGGAGCAGCAGACCAAGATCCTTTTCCTAAAAGTGGTGTAATTAGCAATTGG GTACGTGTTGAAGAGCGTGACTGTTGCAATGACTGCTACCTTGCATTAGAACATGGGCGT CAGTTCATGGATAACATGTCAGGAGGAAAAGTTGATGAAGCACTTGTGAAAAGTTCATGC TTACACCCCTGGTCCAAAAGAAACGATGTGAGTATGCAGTGCTCACAGGATATACTTCGA ATGCTCCTCTCTCTTCAGCCAGTTCTTCAGGATGCCATTCAGAAAAAAAGAACAGTAAGA CCTTGGGGTGTTCAGGGTCCTCTCACTTGGCAACAATTTCATAAAATGGCTGGCCGAGGC TCTTATGGAACTGATGAATCCCCAGAACCACTGCCAATCCCCACATTTTTGTTGGGTTAT GATTATGATTATCTGGTGCTTTCTCCATTTGCTCTTCCTTATTGGGAGAGACTTATGCTG GAACCCTATGGATCTCAAAGAGATATAGCCTATGTTGTACTGTGTCCAGAAAATGAAGCC TTGTTAAATGGAGCAAAAAGCTTTTTTAGAGATCTTACTGCAATATATGAGTCCTGTCGA TTAGGTCAACATAGACCTGTTTCTCGACTGTTAACAGATGGGATCATGAGAGTTGGATCT ACTGCATCAAAGAAACTATCAGAAAAGTTGGTAGCAGAATGGTTTTCTCAGGCAGCTGAT GGTAACAATGAAGCATTTTCTAAACTCAAGCTTTATGCACAAGTCTGCAGATATGACCTA GGTCCTTATCTTGCTTCCCTGCCATTGGACAGCTCTCTACTTTCCCAGCCAAATTTAGTT GCCCCTACAAGTCAGTCTTTGATTACTCCACCTCAGATGACAAATACTGGAAATGCTAAT ACTCCATCTGCCACCTTAGCATCTGCAGCGAGCAGCACTATGACAGTGACTTCAGGTGTT GCCATATCTACTTCAGTTGCCACAGCTAATTCAACTTTGACCACAGCTTCAACTTCATCT TCATCATCCTCCAACTTGAATAGTGGAGTATCATCAAATAAACTACCTTCGTTTCCACCC TTTGGCAGTATGAACAGTAATGCTGCAGGATCCATGTCTACACAAGCAAATACAGTTCAG AGTGGTCAGCTAGGAGGGCAACAGACATCAGCTCTACAGACAGCTGGGATTTCTGGAGAA TCATCTTCACTTCCCACTCAGCCGCATCCTGATGTGTCTGAAAGCACGATGGATCGGGAT AAAGTGGGAATCCCCACAGATGGTGATTCACATGCAGTCACGTATCCACCTGCAATTGTT GTTTATATAATTGATCCTTTTACATACGAAAATACAGACGAGAGCACTAACTCTTCTAGT GTGTGGACATTGGGGCTACTTCGATGCTTTCTAGAAATGGTCCAGACTCTTCCTCCTCAT ATCAAGAGTACTGTTTCTGTACAGATTATTCCTTGTCAGTACCTGTTGCAACCTGTGAAG CATGAAGATAGAGAAATCTATCCCCAGCATTTAAAATCCCTGGCTTTTTCGGCCTTTACC CAGTGTCGGAGGCCACTTCCAACATCAACCAATGTGAAAACATTGACTGGCTTTGGTCCA GGTTTAGCCATGGAAACTGCCCTTAGAAGTCCTGATAGACCAGAGTGTATTCGACTTTAT GCACCTCCTTTTATTCTGGCTCCAGTGAAGGACAAACAGACAGAGCTAGGAGAAACATTT GGAGAAGCTGGACAGAAATATAATGTTCTTTTTGTGGGATACTGTTTATCACATGATCAA AGGTGGATTCTTGCATCTTGCACAGATCTATATGGAGAACTTTTAGAAACTTGTATCATT AACATCGATGTTCCAAATAGGGCTCGTCGGAAAAAAAGTTCTGCTAGAAAATTTGGTCTA CAGAAACTTTGGGAGTGGTGCTTAGGACTTGTACAAATGAGTTCATTGCCATGGAGAGTT GTAATTGGTCGTCTAGGAAGGATTGGTCATGGAGAATTGAAAGATTGGAGCTGTTTGCTG AGTCGTCGAAACTTGCAGTCTCTAAGTAAAAGGCTCAAAGACATGTGTAGAATGTGTGGT ATATCTGCTGCAGACTCCCCTAGCATTCTCAGTGCTTGCTTGGTGGCAATGGAGCCGCAA GGCTCTTTTGTTATTATGCCAGATTCTGTGTCAACTGGTTCTGTATTTGGAAGAAGCACG ACTCTAAATATGCAGACATCTCAGCTAAATACCCCACAGGATACATCATGTACTCATATA CTTGTGTTTCCTACTTCTGCTTCTGTGCAAGTAGCTTCAGCTACTTATACCACTGAAAAT TTGGATTTAGCTTTCAATCCCAACAATGATGGAGCAGATGGAATGGGTATCTTTGATTTG TTAGACACAGGAGATGATCTTGACCCTGATATCATTAATATCCTTCCTGCTTCTCCAACT GGTTCTCCTGTACATTCTCCAGGATCTCATTACCCCCATGGAGGTGATGCGGGCAAGGGT CAGAGTACTGATCGGCTACTATCAACAGAACCTCATGAGGAAGTACCTAATATTCTTCAG CAACCATTGGCCCTTGGTTACTTTGTATCAACTGCCAAAGCAGGTCCATTACCTGACTGG TTCTGGTCAGCATGTCCTCAAGCACAATATCAGTGTCCCCTTTTTCTTAAGGCCTCTTTG CACCTCCACGTGCCTTCAGTGCAATCTGACGAGCTGCTTCACAGTAAACACTCCCACCCA CTTGACTCAAATCAGACTTCAGATGTCCTCAGGTTTGTTTTGGAACAGTACAATGCACTC TCCTGGCTAACCTGTGACCCTGCAACCCAGGACAGACGCTCATGTCTCCCAATTCATTTT GTGGTGCTGAATCAGTTATATAACTTTATTATGAATATGCTGTGA Clone variation with respect to NM_005121.2 2168 g=>a;4320 c=>t >OriGene 5' read for NM_005121 unedited
GTTTAGATTTTGTAATACGACTTATTATAGGGCGGCCGCGAAATTCGCACGAGGCCCGGT GTCTGTGTTTCTCTCTCTGGTCGGAGGCGGCGGTAATGGCGGATGGTGGGTTGTGGCGCC GGCGGCGGCTGCTGTGAGGGACGATGAGTGCCTCCTTCGTGCCGAACGGGGCCAGCCTGG AAGATTGTCACTGTAACCTCTTCTGCCTGGCTGACTTGACAGGAATTAAGTGGAAAAAAT ATGTATGGCAAGGCCCAACTTCTGCCCCTATTCTGTTTCCTGTGACAGAAGAAGACCCCA TTTTGAGCAGTTTTAGTCGCTGCCTTAAGGCAGATGTACTTGGTGTTTGGCGGCGAGATC AAAGACCTGGAAGAAGAGAATTGTGGATATTTTGGTGGGGTGAAGACCCCAGTTTTGCTG ACCTTATTCACCATGACTTATCAGAAGAAGAAGATGGAGTGTGGGAGAATGGACTTTCCT ATGAATGCCGTACTCTGCTTTTCAAAGCAGTTCACAATCTATTGGAACGGTGTTTAATGA ACAGGAATTTTGTACGTATTGGCAAGTGGTTTGTAAAGCCTTATGAAAAAGATGAAAAAC CTATAAATAAAAGTGAACACTTGTCCTGCTCCTTCACCTTTTTCTTGCATGGAGACCAGC ATGTTTGTACCAGTGTGGAAATTAACCAACATCAACCTGTATACCTTCTCAGTGAAGAGC ATATCACCCTTGCTCAACAGTCTAATAGCCCATTTCAAGTTATCTTATGCCCATTTGGAC TAAATGGCACTCTCACCNAGACAGCATTCAAGATGTCTGATTCAGCTACAAANAAATTAA TGGTGAATGGAAACAGTTCTATCCTATCTCATGNNTGCNGAANGNANNATGTCTGAGAAA AACAGNAGATAATGATTGGGAGATGAATCTTAGCTGCGTAGAAGTN >OriGene 3' read for NM_005121 unedited
TATTTATGGACCGCGGGCCGCAATCTANGGATCGGTTTTTTTTTTTTTTTTTTAAAGCAG AAAGGCAGTATAAACCTTCTAGGAAAATTTTTATAAAAGAGGTTAAGAAATATAAGACAA TTTATACATTTAAAAACTTACAATAAATAAGAGAAGAGATGCAGGCATTTTTGAATACTA GATACTATAATCCATACAAGAACATCTTCATGTTCTGAAGCCATATGTTGAAATTCATTG TTCCTCATGTTTCCTCTCCATGCTTTTAATATTCATTTAACATGACTGGGTACTATGGCT CATTACTTTTCACAAATACTGTGACTGGAAAAAAAAAAGGTTAATTTTGCTACGAAAATG TTATAATACGTTTTGTATGATCAGTCATCATCCTAAAGAGTTCAATAGAGTCAATGAAAA ATAGCAGGGTTATAGCCCCTCCCCCCAAGTCAAAACAATATTTGTTGAAGTAATAAGAAT TAGACCCCATCACAAATGACCTTCACTGAGAAGATAATTGTAACTTAATCCTGGAGGGAA ACATCACATTTTTAGCTTGATCTTTTCTTGGCCAGCGCCATCAAATGAAGACCGCAGGGT ATTCCTGACAAAGTTATTTAACCTGATCGCCCTCCCCGAAATGAATCGCGAGACATGACC GACTGAACCGGGATGTAGGATTCCCCGTCACCCCCGAGAGGGCATTGAGCTGACCGCAAA CAACCCTGGAGACCCCGGAACACTGACTAGACCTTAGAGGTGGGGAGGGGCTATTGAGCA ACGGAGCGGGTAGATTGCCCTGGAGGCGCCGGCGGGCGAAGCCAGGCAATAAGAAACGGG GGCCCTGCAATTGTCAGTGGGGACTGTTTGTACCCACCGATTTAGTCATGGGGGCCGCCT CGGCCCGACACACCCGCCCAACTNGGCTGATCGGCGTCGCCGAGAACAACGGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005121 |
| Insert Size | 7180 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005121.1, NP_005112.1 |
| RefSeq Size | 7389 bp |
| RefSeq ORF | 6525 bp |
| Locus ID | 9969 |
| UniProt ID | Q9UHV7 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling
,Haiying Zhou, Jason M. Spaeth, Nam Hee Kim, Xuan Xu, Michael J. Friez, Charles E. Schwartz, and Thomas G. Boyer,
PNAS, Nov 2012; 109: 19763 - 19768.
[MED13]
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