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CRLF1 (NM_004750) Human Untagged Clone
CAT＃: SC126412
CRLF1 (untagged)-Human cytokine receptor-like factor 1 (CRLF1)
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CISS; CISS1; CLF; CLF-1; NR6; zcytor5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004750 edited
CCGCGTCCGCGCCCAGCGACGTGCGGGCGGCCTGGCCCGCGCCCTCCCGCGCCCGGCCTG CGTCCCGCGCCCTGCGCCACCGCCGCCGAGCCGCAGCCCGCCGCGCGCCCCCGGCAGCGC CGGCCCCATGCCCGCCGGCCGCCGGGGCCCCGCCGCCCAATCCGCGCGGCGGCCGCCGCC GTTGCTGCCCCTGCTGCTGCTGCTCTGCGTCCTCGGGGCGCCGCGAGCCGGATCAGGAGC CCACACAGCTGTGATCAGTCCCCAGGATCCCACGCTTCTCATCGGCTCCTCCCTGCTGGC CACCTGCTCAGTGCACGGAGACCCACCAGGAGCCACCGCCGAGGGCCTCTACTGGACCCT CAACGGGCGCCGCCTGCCCCCTGAGCTCTCCCGTGTACTCAACGCCTCCACCTTGGCTCT GGCCCTGGCCAACCTCAATGGGTCCAGGCAGCGGTCGGGGGACAACCTCGTGTGCCACGC CCGTGACGGCAGCATCCTGGCTGGCTCCTGCCTCTATGTTGGCCTGCCCCCAGAGAAACC CGTCAACATCAGCTGCTGGTCCAAGAACATGAAGGACTTGACCTGCCGCTGGACGCCAGG GGCCCACGGGGAGACCTTCCTCCACACCAACTACTCCCTCAAGTACAAGCTTAGGTGGTA TGGCCAGGACAACACATGTGAGGAGTACCACACAGTGGGGCCCCACTCCTGCCACATCCC CAAGGACCTGGCTCTCTTTACGCCCTATGAGATCTGGGTGGAGGCCACCAACCGCCTGGG CTCTGCCCGCTCCGATGTACTCACGCTGGATATCCTGGATGTGGTGACCACGGACCCCCC GCCCGACGTGCACGTGAGCCGCGTCGGGGGCCTGGAGGACCAGCTGAGCGTGCGCTGGGT GTCGCCACCCGCCCTCAAGGATTTCCTCTTTCAAGCCAAATACCAGATCCGCTACCGAGT GGAGGACAGTGTGGACTGGAAGGTGGTGGACGATGTGAGCAACCAGACCTCCTGCCGCCT GGCCGGCCTGAAACCCGGCACCGTGTACTTCGTGCAAGTGCGCTGCAACCCCTTTGGCAT CTATGGCTCCAAGAAAGCCGGGATCTGGAGTGAGTGGAGCCACCCCACAGCCGCCTCCAC TCCCCGCAGTGAGCGCCCGGGCCCGGGCGGCGGGGCGTGCGAACCGCGGGGCGGAGAGCC GAGCTCGGGGCCGGTGCGGCGCGAGCTCAAGCAGTTCCTGGGCTGGCTCAAGAAGCACGC GTACTGCTCCAATCTCAGCTTCCGCCTCTACGACCAGTGGCGAGCCTGGATGCAGAAGTC GCACAAGACCCGCAACCAGGACGAGGGGATCCTGCCCTCGGGCAGACGGGGCACGGCGAG AGGTCCTGCCAGATAAGCTGTAGGGGCTCAGGCCACCCTCCCTGCCACGTGGAGACGCAG AGGCCGAACCCAAACTGGGGCCACCTCTGTACCCTCACTTCAGGGCACCTGAGCCACCCT CAGCAGGAGCTGGGGTGGCCCCTGAGCTCCAACGGCCATAACAGCTCTGACTCCCACGTG AGGCCACCTTTGGGTGCACCCCAGTGGGTGTGTGTGTGTGTGTGAGGGTTGGTTGAGTTG CCTAGAACCCCTGCCAGGGCTGGGGGTGAGAAGGGGAGTCATTACTCCCCATTACCTAGG GCCCCTCCAAAAGAGTCCTTTTAAATAAATGAGCTATTTAGGTGCAAAAAAAAAAAAAAA AAAA >OriGene 5' read for NM_004750 unedited
AGTCGGGATTTGNTAATACGACTTACTATAGGGCGGCCGCGAATTCGCACGAGGCCGCGT CCGCGCCCAGCGACGTGCGGGCGGCCTGGCCCGCGCCCTCCCGCGCCCGGCCTGCGTCCC GCGCCCTGCGCCACCGCCGCCGAGCCGCAGCCCGCCGCGCGCCCCCGGCAGCGCCGGCCC CATGCCCGCCGGCCGCCGGGGCCCCGCCGCCCAATCCGCGCGGCGGCCGCCGCCGTTGCT GCCCCTGCTGCTGCTGCTCTGCGTCCTCGGGGCGCCGCGAGCCGGATCAGGAGCCCACAC AGCTGTGATCAGTCCCCAGGATCCCACGCTTCTCATCGGCTCCTCCCTGCTGGCCACCTG CTCAGTGCACGGAGACCCACCAGGAGCCACCGCCGAGGGCCTCTACTGGACCCTCAACGG GCGCCGCCTGCCCCCTGAGCTCTCCCGTGTACTCAACGCCTCCACCTTGGCTCTGGCCCT GGCCAACCTCAATGGGTCCAGGCAGCGGTCGGGGGACAACCTCGTGTGCCACGCCCGTGA CGGCAACATCCTGGCTGGCTCCTGCCTCTATGTTGGCCTGCCCCCAGAGAAACCCGTCAA CCTCAGCTGCTGGTCCAAGAACATGAAGGACTTGACCTGCCGCTGGACCCCCGGGGCCCC ACGGGAAGACTTTCTTCACACCACCTACCTCCTCAAGTACAAGCTTAGGTGGGATGGGCC GGAACAACACATGGTGAGGGAGTCCCACACAGTGGGGGGCCCCACTTCCTGGCCACATTC CCCAAGTGCCCTCGGGCCTCTTTTTACGCCCCTATAGAGAATCTGGGGTGGGGGGGCACC ACACCGCCCTGGGCGTTTGCGCCCGCTCCTCAGAGTCACTCACGGCCTGCGAAGTNCTCG GGAGGTGGGTGGGACCACAGGCACTCCCCCGTCCCTACGTGGCCACCGCAANCCACCGCC GCGGGGGCCCACGTAGACNACCCT |
| Restriction Sites | Please inquire |
| ACCN | NM_004750 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004750.2, NP_004741.1 |
| RefSeq Size | 1804 bp |
| RefSeq ORF | 1269 bp |
| Locus ID | 9244 |
| UniProt ID | O75462 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Differential secretion of the mutated protein is a major component affecting phenotypic severity in CRLF1-associated disorders
,Jana Herholz, Alessandra Meloni, Mara Marongiu, Francesca Chiappe, Manila Deiana, Carmen Roche Herrero, Giuseppe Zampino, Hanan Hamamy, Yusra Zalloum, Per Erik Waaler, et al.,
European Journal of Human Genetics (16 February 2011) doi:10.1038/ejhg.2010.253 Article
[CRLF1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208303 | CRLF1 (Myc-DDK-tagged)-Human cytokine receptor-like factor 1 (CRLF1) |
CNY 3,656.00 |
|
| RC208303L3 | Lenti ORF clone of Human cytokine receptor-like factor 1 (CRLF1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208303L4 | Lenti ORF clone of Human cytokine receptor-like factor 1 (CRLF1), mGFP tagged |
CNY 5,890.00 |
|
| RG208303 | CRLF1 (tGFP-tagged) - Human cytokine receptor-like factor 1 (CRLF1) |
CNY 4,370.00 |
