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SLC22A2 (NM_003058) Human Untagged Clone
CAT＃: SC126370
SLC22A2 (untagged)-Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2)
CNY 4,144.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OCT2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003058 edited
CTCAGCCTCGCTCCGGGCACGTCGGGCAGCCTCGGGCCCTCCTGCCTGCAGGATCATGCC CACCACCGTGGACGATGTCCTGGAGCATGGAGGGGAGTTTCACTTTTTCCAGAAGCAAAT GTTTTTCCTCTTGGCTCTGCTCTCGGCTACCTTCGCGCCCATCTACGTGGGCATCGTCTT CCTGGGCTTCACCCCTGACCACCGCTGCCGGAGCCCCGGAGTGGCCGAGCTGAGTCTGCG CTGCGGCTGGAGTCCTGCAGAGGAACTGAACTACACGGTGCCGGGCCCAGGACCTGCGGG CGAAGCCTCCCCAAGACAGTGTAGGCGCTACGAGGTGGACTGGAACCAGAGCACCTTCGA CTGCGTGGACCCCCTGGCCAGCCTGGACACCAACAGGAGCCGCCTGCCACTGGGCCCCTG CCGGGACGGCTGGGTGTACGAGACGCCTGGCTCGTCCATCGTCACCGAGTTTAACCTGGT ATGTGCCAACTCCTGGATGTTGGACCTATTCCAGTCATCAGTGAATGTAGGATTCTTTAT TGGCTCTATGAGTATCGGCTACATAGCAGACAGGTTTGGCCGTAAGCTCTGCCTCCTAAC TACAGTCCTCATAAATGCTGCAGCTGGAGTTCTCATGGCCATTTCCCCAACCTATACGTG GATGTTAATTTTTCGCTTAATCCAAGGACTGGTCAGCAAAGCAGGCTGGTTAATAGGCTA CATCCTGATTACAGAATTTGTTGGGCGGAGATATCGGAGAACAGTGGGGATTTTTTACCA AGTTGCCTATACAGTTGGGCTCCTGGTGCTAGCTGGGGTGGCTTACGCACTTCCTCACTG GAGGTGGTTGCAGTTCACAGTTTCTCTGCCCAACTTCTTCTTCTTGCTCTATTACTGGTG CATACCTGAGTCTCCCAGGTGGCTGATCTCCCAGAATAAGAATGCTGAAGCCATGAGAAT CATTAAGCACATCGCAAAGAAAAATGGAAAATCTCTACCCGCCTCCCTTCAGCGCCTGAG ACTTGAAGAGGAAACTGGCAAGAAATTGAACCCTTCATTTCTTGACTTGGTCAGAACTCC TCAGATAAGGAAACATACTATGATATTGATGTACAACTGGTTCACGAGCTCTGTGCTCTA CCAGGGCCTCATCATGCACATGGGCCTTGCAGGTGACAATATCTACCTGGATTTCTTCTA CTCTGCCCTGGTTGAATTCCCAGCTGCCTTCATGATCATCCTCACCATCGACCGCATCGG ACGCCGTTACCCTTGGGCTGCATCAAATATGGTTGCAGGGGCAGCCTGTCTGGCCTCAGT TTTTATACCTGGTGATCTACAATGGCTAAAAATTATTATCTCATGCTTGGGAAGAATGGG GATCACAATGGCCTATGAGATAGTCTGCCTGGTCAATGCTGAGCTGTACCCCACATTCAT TAGGAATCTTGGCGTCCACATCTGTTCCTCAATGTGTGACATTGGTGGCATCATCACGCC ATTCCTGGTCTACCGGCTCACTAACATCTGGCTTGAGCTCCCGCTGATGGTTTTCGGCGT GCTTGGCTTGGTTGCTGGAGGTCTGGTGCTGTTGCTTCCAGAAACTAAAGGGAAAGCTTT GCCTGAGACCATCGAGGAAGCCGAAAATATGCAAAGACCAAGAAAAAATAAAGAAAAGAT GATTTACCTCCAAGTTCAGAAACTAGACATTCCATTGAACTAAGAAGAGAGACCGTTGCT GCTGTCATGACCTAGCTTTGATGGCAGCAAGACCAAAAGTAGAAATCCCTGCACTCATCA CAAAGCCCATACAACTCAACCAAACTTACCCCTGAGCCCTATCAACCTAGGTCTACAGCC AGTGGAGTCTATTGTACACTGTGGAAAAATACCCATGGGACCAGATCCTGCCAAATTCTT CCAGCTCACTTTATTCTCAGCATTCCTAGGACATTGGACATTGGTTTTCTGGAGGGTTTT TTTTCCATCTTTGTATTTTTTTAAATTTGATTCTTTTCTTTGCAATGCTATCTAACCAGA ATACATAGGGGAACTGTGGGCTAGGCAAACAAAATAGAAAAAAGTGTGAAAAACAGTAAA GTTGGGAGAGGAGCATCTATTTTCTTAAAGAAATAAAACACCCAAAACAATATAAAGTTG TCCAGAATGTATGTCAAGAATTTTAGATAGGCCTTTCAGTAACACAGGTGAAGAAATTTT TAAAAATACATTGATTATTATCTAGGTTAGACTTAAAGTGAATCTCAAATAAAAGAATCA GGAATACAACTTAAGTGATCATGAGGTCCTTCCATATTTAGATTGGGTAAGCATGAATGT GTATTTTCTACAAAAGACCTTGAGAAGAGTTCAATAAAAAATGTTAGCATTAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003058 |
| Insert Size | 2400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003058.2, NP_003049.1 |
| RefSeq Size | 2512 bp |
| RefSeq ORF | 1668 bp |
| Locus ID | 6582 |
| UniProt ID | O15244 |
| Protein Families | Transmembrane |
| Gene Summary | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Involvement of organic cation transporter 2 inhibition in potential mechanisms of antidepressant action
,Wang, K;Sun, S;Li, L;Tu, M;Jiang, H;,
Prog. Neuropsychopharmacol. Biol. Psychiatry
,PubMed ID 24657329
[SLC22A2]
|
|
Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2
,Jason A. Sprowl, Giuliano Ciarimboli, Cynthia S. Lancaster, Hugh Giovinazzo, Alice A. Gibson, Guoqing Du, Laura J. Janke, Guido Cavaletti, Anthony F. Shields, and Alex Sparreboom,
PNAS, Jul 2013; 110: 11199 - 11204.
,PubMed ID 23776246
[SLC22A2]
|
|
DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma
,null,
Genome Medicine
,PubMed ID 22196450
[SLC22A2]
|
|
Interaction of Cisplatin with the Human Organic Cation Transporter 2
,Kelly K. Filipski, Walter J. Loos, Jaap Verweij, and Alex Sparreboom,
Clin. Cancer Res., Jun 2008; 14: 3875 - 3880.
[SLC22A2]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207921 | SLC22A2 (Myc-DDK-tagged)-Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2) |
CNY 6,200.00 |
|
| RC207921L1 | Lenti ORF clone of Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2), Myc-DDK-tagged |
CNY 8,600.00 |
|
| RC207921L2 | Lenti ORF clone of Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2), mGFP tagged |
CNY 8,600.00 |
|
| RC207921L3 | Lenti ORF clone of Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2), Myc-DDK-tagged |
CNY 8,600.00 |
|
| RC207921L4 | Lenti ORF clone of Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2), mGFP tagged |
CNY 8,600.00 |
|
| RG207921 | SLC22A2 (tGFP-tagged) - Human solute carrier family 22 (organic cation transporter), member 2 (SLC22A2) |
CNY 7,800.00 |
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