United States
Germany
Japan
United Kingdom
China
BLNK (NM_013314) Human Untagged Clone
CAT＃: SC126228
BLNK (untagged)-Human B-cell linker (BLNK), transcript variant 1
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_013314 edited
CAGAGGCTTACCATGCTGCTCCCTAGGAGGGCCAGGAACTGCTGACGTGACCACTGGACA GTTATTCGTGTCTCTTACAATTACCAAACAGAATGGACAAGCTTAATAAAATAACCGTCC CCGCCAGTCAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAG GTGGAATAATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAA GGGACTACGCTTCAGAGAGCCCTGCTGACGAAGAGCAGCAGTGGTCCGATGACTTTGACA GCGACTATGAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGG AGAACGCTGATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACC CAGCCCTGCCCTTCGCCAGAGGCGAGTATATAGACAATCGATCAAGCCAGAGGCATTCCC CACCCTTCAGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCA CCTCCACCCTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAG GCCTCCTTGAGGATGAGGCTGATTATGTGGTCCCCGTGGAAGATAATGATGAAAACTATA TTCATCCCACAGAAAGCAGTTCACCTCCACCTGAAAAAGCTCCCATGGTGAATAGATCAA CCAAGCCAAATTCCTCAACGCCCGCCTCTCCTCCAGGAACAGCTTCAGGTCGAAACAGTG GGGCCTGGGAAACCAAGTCACCTCCACCAGCTGCACCATCCCCGTTGCCACGGGCCGGGA AAAAACCAACGACACCACTGAAGACAACTCCAGTTGCCTCTCAACAGAATGCTTCAAGTG TTTGTGAAGAAAAACCTATACCTGCTGAACGCCACCGAGGGTCAAGTCACAGACAAGAAG CTGTGCAGTCACCAGTGTTTCCTCCTGCCCAGAAACAAATCCACCAAAAACCCATACCTC TGCCAAGATTTACAGAAGGGGGAAACCCAACTGTGGATGGGCCCCTACCCAGCTTTTCAT CTAATTCCACTATTTCAGAACAGGAAGCTGGCGTTCTCTGCAAGCCATGGTATGCTGGAG CCTGTGATCGAAAGTCTGCTGAAGAGGCATTGCACAGATCAAACAAGGATGGATCATTTC TTATTCGGAAAAGCTCTGGCCATGATTCCAAACAACCATATACACTAGTTGTATTCTTTA ATAAGCGAGTATATAATATTCCTGTGCGATTTATTGAAGCAACAAAACAATATGCCTTGG GCAGAAAGAAAAATGGTGAAGAGTACTTTGGAAGTGTTGCTGAAATCATCAGGAATCATC AACATAGTCCTTTGGTTCTTATTGACAGTCAGAATAACACAAAAGATTCCACCAGACTGA AGTATGCAGTTAAAGTTTCATAAAGGGGGAAAAAAAAGATCAATACCATTGCTTCAGACA CTTTCCCAAAGTTTCTCCTTTTGAGAAAAAGTCCCAAAACTTCATATTTTGGATTATGAA TCATCCAGTAATAAAATGGAAGATGGAGTCAGCTATTGAAGTGGTCATCCATTTCTTTTT AAGAAGCTCATGTGGACTTGTTCTATTGCCTGACCTGATGAACTGTTAATATCTGGTGAG GTTGAGTTATCATGCTACTAATATTTTCCAAATAAATATTTTTATTTTTAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_013314 unedited
AGGTTCATATTTGTATACGACNACTATAGGCGGCCGCGTAATTCGCACGAGGCAGAGGCT TACCATGCTGCTCCCTAGGAGGGCCAGGAACTGCTGACGTGACCACTGGACAGTTATTCG TGTCTCTTACAATTACCAAACAGAATGGACAAGCTTAATAAAATAACCGTCCCCGCCAGT CAGAAGTTGAGGCAGCTTCAAAAGATGGTCCATGATATTAAAAACAATGAAGGTGGAATA ATGAATAAAATCAAAAAGCTAAAAGTCAAAGCACCTCCAAGTGTTCCTCGAAGGGACTAC GCTTCAGAGAGCCCTGCTGACGAAGAGCAGCAGTGGTCCGATGACTTTGACAGCGACTAT GAAAATCCAGATGAGCACTCGGACTCAGAGATGTACGTGATGCCCGCCGAGGAGAACGCT GATGACAGCTACGAGCCGCCTCCAGTAGAGCAGGAAACCAGGCCGGTTCACCCAGCCCTG CCCTTCGCCAGAGGCGAGTATATAGACAATCGATCAAGCCAGAGGCATTCCCCACCCTTC AGCAAGACACTTCCCAGTAAGCCCAGCTGGCCTTCAGAGAAAGCAAGGCTCACCTCCACC CTGCCGGCCCTGACTGCTTTGCAGAAACCTCAAGTCCCACCCAAACCCAAAGGCCTCCTT GAGGATGAGGCTGATTATGTGGTCCCCGTGGAAGATAATGATGAAAACTATATTCATCCC ACAGAAAGCAGTTCACCTCCACCTGAAAAAGCTCCCATGGTGAATAGATCAACCAAGCCA AATTCCTCAACGCCCGCCTCTCCTCCAGGAACAGCTTCAGGTCGAAACAGTGNGGCCTGG GAAACCAAGTCACCTCCACCAGCTGCACCATCCCCGTTGCCCACGGGCCGGNAAAAAACA ACGACACCACTGAAGAACACTCCAGTTGCCTCTCAACAGAATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_013314 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_013314.2, NP_037446.1 |
| RefSeq Size | 1828 bp |
| RefSeq ORF | 1371 bp |
| Locus ID | 29760 |
| UniProt ID | Q8WV28 |
| Protein Families | Druggable Genome |
| Protein Pathways | B cell receptor signaling pathway, Primary immunodeficiency |
| Gene Summary | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202488 | BLNK (Myc-DDK-tagged)-Human B-cell linker (BLNK), transcript variant 1 |
CNY 3,656.00 |
|
| RC202488L1 | Lenti ORF clone of Human B-cell linker (BLNK), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202488L2 | Lenti ORF clone of Human B-cell linker (BLNK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC202488L3 | Lenti ORF clone of Human B-cell linker (BLNK), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202488L4 | Lenti ORF clone of Human B-cell linker (BLNK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG202488 | BLNK (tGFP-tagged) - Human B-cell linker (BLNK), transcript variant 1 |
CNY 4,370.00 |
