CD68 (BC015557) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CD68 antigen; CD68 molecule; DKFZp686M18236; GP110; macrophage antigen CD68; macrosialin; OTTHUMP00000135285; SCARD1; scavenger receptor class D, member 1
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC015557 edited GGGAGCAGGGTTGAGCAACTGGTGCAGACAGCCTAGCTGGACTTTGGGTGAGGCGGTTCA GCCATGAGGCTGGCTGTGCTTTTCTCGGGGGCCCTGCTGGGGCTACTGGCAGCCCAGGGG ACAGGGAATGACTGTCCTCACAAAAAATCAGCTACTTTGCTGCCATCCTTCACGGTGACA CCCACGGTTACAGAGAGCACTGGAACAACCAGCCACAGGACTACCAAGAGCCACAAAACC ACCACTCACAGGACAACCACCACAGGCACCACCAGCCACGGACCCACGACTGCCACTCAC AACCCCACCACCACCAGCCATGGAAACGTCACAGTTCATCCAACAAGCAATAGCACTGCC ACCAGCCAGGGACCCTCAACTGCCACTCACAGTCCTGCCACCACTAGTCATGGAAATGCC ACGGTTCATCCAACAAGCAACAGCACTGCCACCAGCCCAGGATTCACCAGTTCTGCCCAC CCAGAACCACCTCCACCCTCTCCGAGTCCTAGCCCAACCTCCAAGGAGACCATTGGAGAC TACACGTGGACCAATGGTTCCCAGCCCTGTGTCCACCTCCAAGCCCAGATTCAGATTCGA GTCATGTACACAACCCAGGGTGGAGGAGAGGCCTGGGGCATCTCTGTACTGAACCCCAAC AAAACCAAGGTCCAGGGAAGCTGTGAGGGTGCCCATCCCCACCTGCTTCTCTCATTCCCC TATGGACACCTCAGCTTTGGATTCATGCAGGACCTCCAGCAGAAGGTTGTCTACCTGAGC TACATGGCGGTGGAGTACAATGTGTCCTTCCCCCACGCAGCACAGTGGACATTCTCGGCT CAGAATGCATCCCTTCGAGATCTCCAAGCACCCCTGGGGCAGAGCTTCAGTTGCAGCAAC TCGAGCATCATTCTTTCACCAGCTGTCCACCTCGACCTGCTCTCCCTGAGGCTCCAGGCT GCTCAGCTGCCCCACACAGGGGTCTTTGGGCAAAGTTTCTCCTGCCCCAGTGACCGGTCC ATCTTGCTGCCTCTCATCATCGGCCTGATCCTTCTTGGCCTCCTCGCCCTGGTGCTTATT GCTTTCTGCATCATCCGGAGACGCCCATCCGCCTACCAGGCCCTCTGAGCATTTGCTTCA AACCCCAGGGCACTGAGGGGGTTGGGGTGTGGTGGGGGGGTACCCTTATTTCCTCGACAC GCAACTGGCTCAAAGACAATGTTATTTTCCTTCCCTTTCTTGAAGAACAAAAAGAAAGCC GGGCATGACGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCAC TGGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAA ATACAATTAGCCAGGTGTGGCGGCGTAATCCCAGCTGGCCTGTAATCCCAGCTACTTGGG AGGCTGAGGCAGAACTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGTCATCGCGC CACTAAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCAGACTGTCTCAA ATAAATAAATATGAGATAATGCAGTCGGGAGAAGGGAGGGAGAGAATTTTATTAAATGTG ACGAACTGCCCCCCCCCCCCCAGCAGGAGAGCAGCAAAATTTATGCAAATCTTTGACGGG GTTTTCCTTGTCCTGCCAGGATTAAAAGCCATGAGTTTCTTAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC015557 unedited GGGCGTTCGGGATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGG GGAGCAGGGTTGAGCAACTGGTGCAGACAGCCTAGCTGGACTTTGGGTGAGGCGGTTCAG CCATGAGGCTGGCTGTGCTTTTCTCGGGGGCCCTGCTGGGGCTACTGGCAGCCCAGGGGA CAGGGAATGACTGTCCTCACAAAAAATCAGCTACTTTGCTGCCATCCTTCACGGTGACAC CCACGGTTACAGAGAGCACTGGAACAACCAGCCACAGGACTACCAAGAGCCACAAAACCA CCACTCACAGGACAACCACCACAGGCACCACCAGCCACGGACCCACGACTGCCACTCACA ACCCCACCACCACCAGCCATGGAAACGTCACAGTTCATCCAACAAGCAATAGCACTGCCA CCAGCCAGGGACCCTCAACTGCCACTCACAGTCCTGCCACCACTAGTCATGGAAATGCCA CGGTTCATCCAACAAGCAACAGCACTGCCACCAGCCCAGGATTCACCAGTTCTGCCCACC CAGAACCACCTCCACCCTCTCCGAGTCCTAGCCCAACCTCCAAGGAGACCATTGGAGACT ACACGTGGACCAATGGTTCCCAGCCCTGTGTCCACCTCCAAGCCCAGATTCAGATTCGAG TCATGTACACAACCCCAGGTGGAGGAGAGGCCTNGGGCATCTCTGTACTGAACCCCAACA AACCAAGTCCAGGGAAGCTGTGAGGGTGCCCATCCCCACCTGCTTCTCTCATTCCCTATG GACACCTCAGCTTTGGATTCATGCAGGACCTCCCGCAGAAGGGGGTCTACCTGAGCTACA TGGGCGTGGGAGTACAATGTGTGCTTCCCCCACGCAGCACAGTGGACATTCTCGGCTCAA ATGCATCCCTTCGAGATCTCCAGCC
Restriction Sites	Please inquire
ACCN	BC015557
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC015557.2, AAH15557.1
RefSeq Size	1739 bp
RefSeq ORF	1062 bp
Locus ID	968
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Lysosome
Gene Summary	This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

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