PRR7 (BC004261) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	MGC10772; proline rich 7 (synaptic)
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC004261 edited GCCCAGCGCTCGGAGCCGCTTTCGCTGCCACTGTCTGCTCCCCCGGGCCGCCGCCGCCTC CCCCCGCAGGCCCGGGGCTCTGTCCGCTGGGCCCGCGCTGCTCGCCCCGAGCCAGGAGAA CGAGCTCGAGGAGGATGCCTGGGCCCGTCCCGCGCGGCCCCGGGTGAGGCACGCCCGCGC GCCCGCCGGCGCCATGGGAAGGAGCGGGCGCCGCTGCTGTCCCCCGCCGGCGCGCGCACG ACTTGAGACCTGCCACGGGCAGCCCCCGGCCGCGGGTCCCCGAGTGACGCTGGCGGCACC TGAGAGTGTGGCGCGGGCCCGGGGCCACGCAGCGGAGCCCAGTGTCCAGTGAAGCGTCTG AGGACCCGCCGCCCGTGCCGCCGCCATGGTGATGTCCCAGGGCACCTACACGTTCCTCAC GTGCTTCGCCGGCTTCTGGCTCATCTGGGGTCTCATCGTCCTGCTCTGCTGCTTCTGCAG CTTCCTGCGCCGCCGCCTCAAACGGCGCCAGGAGGAGCGACTGCGCGAGCAGAACCTGCG CGCCCTAGAGCTGGAGCCCCTCGAACTCGAGGGCAGTCTGGCCGGGAGCCCCCCGGGCCT GGCGCCGCCGCAGCCACCACCACACCGTAGCCGCCTGGAGGCGCCGGCTCACGCGCACGC GCACCCACACCCGCACCACCACGCGCTCCCGCACCCGCCGCCTACGCACCTGTCGGTGCC GCCACGGCCCTGGAGCTACCCGCGCCAAGCGGAATCGGACATGTCCAAACCACCGTGTTA CGAAGAGGCGGTGCTGATGGCAGAGCCGCCGCCGCCCTATAGCGAGGTGCTCACGGACAC GCGCGGCCTCTACCGCAAGATCGTCACGCCCTTCCTGAGTCGCCGCGACAGCGCGGAGAA GCAGGAGCAGCCGCCTCCCAGCTACAAGCCGCTCTTCCTGGACCGGGGCTACACCTCGGC GCTGCACCTGCCCAGCGCCCCTCGGCCCGCGCCGCCCTGCCCAGCCCTCTGCCTGCAGGC CGACCGTGGCCGCCGGGTCTTCCCCAGCTGGACCGACTCAGAGCTCAGCAGCCGCGAGCC CCTGGAGCACGGAGCTTGGCGTCTGCCGGTCTCCATCCCCTTGTTCGGGAGGACTACAGC CGTATAGAGGGGCGCCCGGCGCCCCGGGCCCCACCGGCGGACTCCTGGCCTGACTGCGGG GCTTTTTAAATGCTTCCCTGGACTGCGGGGAGGGGCGGGGGGAGGGAGGGATTTCTTATC CCGTTTGTTACATTTTGAGGATAATAAAGGTGTGTGATCTGGTTTGGTAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC004261 unedited NAGGTCAAACATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCCCAGC GCTCGGAGCCGCTTTCGCTGCCACTGTCTGCTCCCCCGGGCCGCCGCCGCCTCCCCCCGC AGGCCCGGGGCTCTGTCCGCTGGGCCCGCGCTGCTCGCCCCGAGCCAGGAGAACGAGCTC GAGGAGGATGCCTGGGCCCGTCCCGCGCGGCCCCGGGTGAGGCACGCCCGCGCGCCCGCC GGCGCCATGGGAAGGAGCGGGCGCCGCTGCTGTCCCCCGCCGGCGCGCGCACGACTTGAG ACCTGCCACGGGCAGCCCCCGGCCGCGGGTCCCCGAGTGACGCTGGCGGCACCTGAGAGT GTGGCGCGGGCCCGGGGCCACGCAGCGGAGCCCAGTGTCCAGTGAAGCGTCTGAGGACCC GCCGCCCGTGCCGCCGCCATGGTGATGTCCCAGGGCACCTACACGTTCCTCACGTGCTTC GCCGGCTTCTGGCTCATCTGGGGTCTCATCGTCCTGCTCTGCTGCTTCTGCAGCTTCCTG CGCCGCCGCCTCAAACGGCGCCAGGAGGAGCGACTGCGCGAGCAGAACCTGCGCGCCCTA GAGCTGGAGCCCCTCGAACTCGAGGGCAGTCTGGCCGGGAGCCCCCCGGGCCTGGCGCCG CCGCAGCCACCACCACACCGTAGCCGCCTGGAGGCGCCGGCTCACGCGCACGCGCACCCA CACCCGCACCACCACGCGCTCCCGCACCCGCCGCCTACGCACCTGTCGGTGCCGCCACGG CCCTGGAGCTACCCGCGCCAAGCGGAATCGGACATGTCCAAACCACCGTGTTACNAANAG GCNGTGCTGATGGCAGAGCCGCCCCCGCCTATAGCGAGGTGCTCACGGACACGCGCGGCC TCTACGCAAGATCGTCACGCCCTTCCTGATTGCCGCGACAGCGCCGT
Restriction Sites	Please inquire
ACCN	BC004261
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC004261.1, AAH04261.1
RefSeq Size	1351 bp
RefSeq ORF	759 bp
Locus ID	80758
Protein Families	Transmembrane
Gene Summary	Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:21460222). Might promote apoptosis in T cells (PubMed:21460222).[UniProtKB/Swiss-Prot Function]

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