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MTHFR (NM_005957) Human Untagged Clone
CAT＃: SC125935
MTHFR (untagged)-Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR)
CNY 4,896.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005957 edited
CCGGCGGCCGAGCGTTCTGAGTCACCCGGGACTGGAGGTAGGAACCCAGCCATGGTGAAC GAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGT GAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCTGAGCGGCATGAG AGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAA TTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATG GCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCA GACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAG ACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCAC AAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGAC CAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGA AGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAA GCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGAT TTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGC ACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCAC TCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTG ATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTG AGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTC AACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCC AGGCGTCCCCTACCCTGGGCTCTCAGTGCCCACCCCAAGCGCCGAGAGGAAGATGTACGT CCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAG TTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTAC TACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAG GAGCTGACCAGTGAAGCAAGTGTCTTTGAAGTCTTTGTTCTTTACCTCTCGGGAGAACCA AACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAG ACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAAC TCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGC GGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAA GCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTG AAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATC TTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGG AAGGACGAGGCCTTTGCCCTGTGGATTGAGCAGTGGGGAAAGCTGTATGAGGAGGAGTCC CCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGAC AATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTC AACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGACCCTGCGTCCTGACGCCC TGCGTTGGAGCCACTCCTGTCCCGCCTTCCTCCTCCACAGTGCTGCTTCTCTTGGGAACT CCACTCTCCTTCGTGTCTCTCCCACCCCGGCCTCCACTCCCCCACCTGACAATGGCAGCT AGACTGGAGTGAGGCTTCCAGGCTCTTCCTGGACCTGAGTCGGCCCCACATGGGAACCTA GTACTCTCTGCTCTAGCCAGGAGTCTGTGCTCTTTTGGTGGGGAGCACTTGCGTCCTGCA GAGGACCACAGTGGGTGGCACCTCCTGAGAAGGCGAGGAGAGTGGTTGTTGCCAACTAAG CCCTCGAACCAAGGCAGCCTCCAGAGCCAGCCTGGGACTCCCAGTGAACTTACACTTGGA GCCCGTGCAGTACAGGCAAAACACGCAAGGGCATCAGGCACTGGTGGCATCGTAGAAGAG ATGTGGCAAAGTGCTGTACCCTTCCACCTCCTAGAGGTGGGCAGCTGGGCCCCACCTACT TGTGACTGAAGGGGCACACCACTGCCCTGCCTGCCCACTTAGCCGTCCATGGCACCAGCC CCCTGGATGGGCATTGGGCTGACACCTACCATGCTGCTTTTTGGCACAGTTGTCTATTCT GAGCCTTGAGAGAAAAAGTGCCCCTTAAGGGTTGAAGGCAGTCTGAACCCTTGTGCTTGG TGGGGCTCGTGGCCTTCCCCTTTTGCCTGGCTGTGGAGGCCTGATGCTGCCCCGTTCCCT GTCAGAGGCTAAGATGAGATTTGCCAGCACAGGGGCCCCAGATCTGCCTGGGCCTGTGCA GCAGCCCAGCTTCCTGGTGTATTTTTCAGGTAGGCCCTTGTCCTGCCAGCTGCCTTCCTC ATCCCCTCGTCCTGTCCCAGAGGTTATCTGCCTGGCCTGGCTCCCCACGAGTCACCTGCA AGCCCCAGGGCCTGGGGGCAGTGACTGGCAGGTGCAGATGGGCTGTTTCGTGTAGTGGAA GAGCAGCCTGATGGCCAAGGGGGTGGACGCAATTGTGGGATGTCCTCTTTACTCCCTTCC TGGCCTCACTGGCTGGGGCAGAGGGGCAGCCGCTAGGAGAGACTGAAAGCAGCAGCTAGG ACTGAGGAGTGGGTTTTATTGTCCTTCAGAGCTCTTCAAGCTGTCCCCTCTGTCATCACT CCCTGGATGTGTGGGGCATGGTTCCTTCCCTGGGAAGGCTAAGTTCAGTTCTGTTTTTTA TTCTATGAGAACAAGTCACAGCTGCAGCTGGGCCCCATGCTCTGCCCCAAGCCCCCAACC CCGCGGTGCTCCGGCGGCTTCCTGTCCACTCTCGGGGCCCTTGGGGCCTGGCTTGCTCCA GGGTCTTGGGCTACTGGCAGCTCCTCTCCTTGGGCTCCTGGCTGCCAGGCGTTGGTGCCA CTTCTTAAAGGCCTGGAACCAGGGAGGAGAGGAAATGCTATTGTTGTGGGCTTTCTCCGG GGTCTGTGCTGTGCCTGCTAGAGCAACCCCTGTACCCAGCTCCTTTTGTCCCCAGGGCCC CTCCCTCTGCCCCAAGCAGCCAGCCAGTCTTGCCTAGGCCAAATGCACAAGCTCAGAATA GATCTGATGGTGAGCTGGGAAGCTGTACTCAGAGCAGAGCAAATGAGGGAGGGGGCGCTC AGGACCCAGGCCCTCCATGGGCTAGTGTGAGTGGCAGCCATGCCTCATGCCACACCTTCT TCGCAAACTGATGGACCGGGTGGGCCTGGCCTGAGCTGGGGCCACAAATCAAAGCAAGGG CTCCAGTATCCAGCCTGTGTGTTCTGTAATGGAACTGACCCCCTCCCCTGAAAACGAAGG GGCCCCGGGGCTGGCAAGCAGGGAAAGCTCCACGGTGCGCGGCTGTGGCACAGACTTCTG GAAGGCTGGCTGAGTGGAATGCAGGGAAGAGGGCAGTACCTGGGAAAGGACCCACCCATC TTCCTGCTGCTGTAACTGCTGAGCCACTCGCAGTCGCAGGATCCGCTGCCACCACGTCTG CCAGGCCCATCTCAGGTGCCACTCCCTGAGCTTTGGGGACAGTTGGCAGAGAAGGCCTCT TGTGCTCACGCTCCCCCGCAGTCCCCAGCCCTTCTGCCTTTCTCCCCCGACACTGCTGCA CCAGAGTGAAAGGGCTATGGCAAGGGGGTGTCATCTGAGGAGTATTAAGAATGCAGATTC CTGGGCCTGTCCCCCAAGGTTTTGGAGTCAGTAGGTCCAAGGGCCATACTTTTGAGAGGG GTTTGGGTTAAGTATGAGGTGAAATGGGAGATGGTCAGTGTGGAGAGGGGTGCACCCACT CACCAGGGTCCGCACCAGCTGCTCTGCCCCTTGGGCATCCACCCAGTGCTGCCATGCCAC TGCCAGGCACCTGGCCTGCTGGGAACCCCGCAGCCCGTGAAGCAGTGCCTCGAGGCACCG GCGCTGCAGGTACTTCCTCCTGATGGCCAAGAGCATCGTGACCCTTCAGGGCCAGAAGGA GGGCAGAGCCATGGGCCTGGGCCTGCTTTTCCAGGATCCTGCAGGAACGAGCACTGGCCA GAGAGGGCCCAGCTGTAGCCATGGCTCAGGCAAGCCCCTCAGCCCTTGCCCCCATCCCTC GGACCCACCAAACTGCACACACAGCTCCTCTTACCGTAGCCTCCGTTTATGGGCCTTGCT TTGGGCTTTGGAGGCTCTGGGCTCAGGGCTGGAGTGCGCTCTTGGTCCCTGGTCCCTCGT CCACAGGGGCAGGCCTGGGACCCAGCTACTCTGTCCAGGCCACTGTGGCCAGAGCTGGAA GGCAGGGCAGAGGGAATGTTCCCTGCACCCTGGAAAGGGGAGTTGAGTCACAAGAGTTTA AGGTGGGTCCAGGAAGGCAGCTGCTCTTAGTGCCCGCTTAGGAGTTGAGTACAGTGAGGA GGGTGGAGGAAGGTGCTGAGCTTAGCCTTGTGCCCTGCCCCCATCTCCCCAGGCCTCCAG CCTCTCACGGCTGCCTGCCGCCCAAAGAGAAATCACAGGGGCGGGGCAGGAATGCAAAGT GTTTTCTCAGAACAGCTGAAACATTCCGAAGAGGGAATGGATGGGGAGAATGGTCAATAC ACATAAGACCGTGTCCCAAGGAGCTGATTTCCAGGCCCCTGAGGACTGGAGACCGCTTCA CCCCTGCACTTCAGACACCGTTTGTCCCCCGGGGCAAGGTCTCCTTACTCTGAGCCCAGG CCGTTCCCCTTGGCTTCCTCCGTCCACCCAGGCTGCACTGCAGTGATGGCGCGGGAGGCA CCAGCTCTGTGGCCTGTGTCCAGCAGCTGTGGGTCTGAAGGAATAGCCAGAGAGGAGCAC CTGAACCCCATGGGCTTGGACTTCCTGGGGCCCCGCTGGGATTTCTTCGCTGCTCTAGCT GGCAGGACACATCCCGGCCTCTTCCACCCATTCCCCCATGTGGCTGAAGACATTCCAACA ATGGGGTGGGCCCATAATAGTTAGCCCTCAGTCAGTTCCCGGAGCACAGCCCTGGGAGGG GGCTATTTCTCTCCCCACTGAAAACATTTCAAAGCTGAGTTACTTGTCTGAGGCCTCATC CCTCGGAAGCCGTCTGACTCCAGAGTCTGAGCCCCCGGCTAGTACCCTATAGAGAGGGGG CTCTCCAAAGGGGCTGCTGGGGCATGTGTGCCTGTGGCAGAAAAGAGGAGACCCTGGAAT TCAGCACCCTGGGTGCCATTCCCAGCGTTTAGTTTCTAGAGGCCTCAGTTTCTCCATCAG CTTATGGGATCCTTGTCTTTACTGACAAGAATGGAATAGAAATGTAAAAGTACTCTGAAA AGCAATTGCCCTGTAACTTATCTAGAAAGAAAAGACCCTGAGACTCCAGAATCTGCTGTT GCCATAGCCCCATATGTGTGAATTCTGCAACTAGCCAAGGCTAGTTCCTTTCAATTCCAT TTAAAAAACAAAAACCAGCAGGTGTGGTGGCTCATGGCGTAATGGGCCTGCCCAATGCTT TGGGAGGCCAAGGCAGATAGATCGCTTGAGCCCAGGAGTTTGAGACAAGCCCTGGCAACA TAGTGAGATCCCATTTCTACAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_005957 unedited
NGGGTCAGATTTTGTATACGACTCATATAGGCGGCGCGCGAATTCGCACGAGGCCGGCGG CCGAGCGTTCTGAGTCACCCGGGGGTGGAGGTAGGAACCCAGCCATGGTGAACGAAGCCA GAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCT CCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCTGAGCGGCATGAGAGACTCC GGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCC CTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAG GTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGG AGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCC TGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTA AGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGG AAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGT TTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCCGAGCAGGGA GCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAAGTGTCTGCGGGAGCCGATTTCATCA TCACGCAGCTTTTTCTTTGAGGCTGACACATTCTTTTCGCTTTGTGAAGGCATGCACCGA CATGGGCATCACTTGGCCCATCGTCCCCGGGATCTTTTCCATNCAGGGCTACACTCCCTT TCGCAGCTGG |
| Restriction Sites | Please inquire |
| ACCN | NM_005957 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005957.2, NP_005948.2 |
| RefSeq Size | 6099 bp |
| RefSeq ORF | 1971 bp |
| Locus ID | 4524 |
| UniProt ID | P42898 |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Methane metabolism, One carbon pool by folate |
| Gene Summary | The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009] Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208588 | MTHFR (Myc-DDK-tagged)-Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR) |
CNY 4,888.00 |
|
| RC208588L1 | Lenti ORF clone of Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR), Myc-DDK-tagged |
CNY 7,288.00 |
|
| RC208588L2 | Lenti ORF clone of Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR), mGFP tagged |
CNY 5,890.00 |
|
| RC208588L3 | Lenti ORF clone of Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208588L4 | Lenti ORF clone of Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR), mGFP tagged |
CNY 5,890.00 |
|
| RG208588 | MTHFR (tGFP-tagged) - Human methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR) |
CNY 4,370.00 |
