USP5 (BC005139) Human Untagged Clone
CAT#: SC125841
USP5 (untagged)-Human ubiquitin specific protease 5 (isopeptidase T), mRNA (cDNA clone MGC:1586 IMAGE:3506801), complete cds
CNY 3,816.00
货期*
现货
规格
Product images
经常一起买 (4)
Anti-USP5 mouse monoclonal antibody, clone OTI2E3 (formerly 2E3)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ISOT; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ubiquitin isopeptidase T; ubiquitin specific peptidase 5; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T) |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for BC005139 edited
GCCGTGTGTGGAGAAGCTGCTGCCGGTGTCATGGCGGAGCTGAGTGAGGAGGCGCTGCTG TCAGTATTACCGACGATCCGGGTCCCTAAGGCTGGAGACCGGGTCCACAAAGACGAGTGC GCCTTCTCCTTCGACACGCCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTT CTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCAATAAGACCGGCCAGCGAGTCTAC TTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACTGGAGAC CCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGC GAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTGTCATTTTGCCAGATTACCTGGAG ATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACCAGTGCA GTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGAT GGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCT CGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTGTGGCTC AACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAAC AACCACGCTGTGGAGCACTACCGAGAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACC ATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTGGACCCC AGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGAC AAGACGATGACTGAGTTGGAGATAGACATGAACCAGCGGATTGGTGAATGGGAGCTGATC CAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATCCGGAAC CTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTC CAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCCAGAATGCCCCGACGGACCCTACC CAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAGTATTCC AAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGAT GGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACC AACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAGAGGAAT TGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAG TGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAGTTGACTACATCATGCAGCTGCCT GTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAGAAGCGG CAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGC TCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTG CAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTACCTGGTC ATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCC ATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGA GAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAAGGTAGC CTTGGTTTCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTCCG ACATCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATG GACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCCATGAAC TGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCT AGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACC ATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACGAACAAT AGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCT GCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTG GGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGTCACATG GGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTG ATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATC TACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAGGGCAGG GGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTG TACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGC TGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACGGGAGGG GCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGC TCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTG CGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTCCCCTCC CCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCC GACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGTCTCTTCCTTGTCCTTCTCTGGAA AATGCCAAAATACACGATGTGAATAAAAGTACAACGGCTAAAAAAAAAAAAAAAAAAAAA AAAAA >OriGene 5' read for BC005139 unedited
TTCAGAATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGGCCGTG TGTGGAGAAGCTGCTGCCGGTGTCATGGCGGAGCTGAGTGAGGAGGCGCTGCTGTCAGTA TTACCGACGATCCGGGTCCCTAAGGCTGGAGACCGGGTCCACAAAGACGAGTGCGCCTTC TCCTTCGACACGCCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGC TTTGGGAAACAGTATGTGGAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCAC CTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCC CGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAG AAGTTTGAATTAGACGAGGATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCC CGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAG GCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAA GTACGGCAGGTGTCTAAGCATGCCTTCAGCCTCAAGCAGTTGGGACACCCTGCTCGAATC CCTCCTGTGGCTGGAAGTGCNTCAAGTGTGACATGAGAGAGGACCTGTGGCTCAACCTGA CTGATGGGCTCATCCTCTGTGGGCGACGCTACTTCGATGGGCGTGGGGGCAACANCCACG CTGTGGAGCACTACCGAGAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCCACATCACCC CTGATGGAGCTGACGTGTACTCATATGATGAAGATGACATGGTCCTGGACCCCAGCCTGG CTGACCCCTGTCCCACTTCGCATCAACTGCTGAAATGCCAAAACAACAACAA |
Restriction Sites | Please inquire |
ACCN | BC005139 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC005139.2, AAH05139.1 |
RefSeq Size | 3185 bp |
Locus ID | 8078 |
Protein Families | Druggable Genome, Protease |
Gene Summary | Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010] |
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