United States
Germany
Japan
United Kingdom
China
MCCC2 (NM_022132) Human Untagged Clone
CAT＃: SC125472
MCCC2 (untagged)-Human methylcrotonoyl-CoA carboxylase 2 (beta) (MCCC2), nuclear gene encoding mitochondrial protein
CNY 4,200.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MCCB; MCCCbeta |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_022132 edited
TCGGCACGAGCTGCAAGGACCTGAGCTCAGCTTCCGCCCCAGCCAGGGAAGCGGCAGGGG AAAGCACCGGCTCCAGGCCAGCGTGGGCCGCTCTCTCGCTCGGTGCCCGCCGCCATGTGG GCCGTCCTGAGGTTAGCCCTGCGGCCGTGTGCCCGCGCCTCTCCCGCCGGGCCGCGCGCC TATCACGGGGACTCGGTGGCCTCGCTGGGCACCCAGCCGGACTTGGGCTCTGCCCTCTAC CAGGAGAACTACAAGCAGATGAAAGCACTAGTAAATCAGCTCCATGAACGAGTGGAGCAT ATAAAACTAGGAGGTGGTGAGAAAGCCCGAGCACTTCACATATCAAGAGGAAAACTATTG CCCAGAGAAAGAATTGACAATCTCATAGACCCAGGGTCTCCATTTCTGGAATTATCCCAG TTTGCAGGTTACCAGTTATATGACAATGAGGAGGTGCCAGGAGGTGGCATTATTACAGGC ATTGGAAGAGTATCAGGAGTAGAATGCATGATTATTGCCAATGATGCCACCGTCAAAGGA GGTGCCTACTACCCAGTGACTGTGAAAAAACAATTACGGGCCCAAGAAATTGCCATGCAA AACAGGCTCCCCTGCATCTACTTAGTTGATTCGGGAGGAGCATACTTACCTCGACAAGCA GATGTGTTTCCAGATCGAGACCACTTTGGCCGTACATTCTATAATCAGGCAATTATGTCT TCTAAAAATATTGCACAGATCGCAGTGGTCATGGGCTCCTGCACCGCAGGAGGAGCCTAT GTGCCTGCCATGGCTGATGAAAACATCATTGTACGCAAGCAGGGTACCATTTTCTTGGCA GGACCCCCCTTGGTTAAAGCGGCAACTGGGGAAGAAGTATCTGCTGAGGATCTTGGAGGT GCTGATCTTCATTGCAGAAAGTCTGGAGTAAGTGACCACTGGGCTTTGGATGATCATCAT GCCCTTCACTTAACTAGGAAGGTTGTGAGGAATCTAAATTATCAGAAGAAATTGGATGTC ACCATTGAACCTTCTGAAGAGCCTTTATTTCCTGCTGATGAATTGTATGGAATAGTTGGT GCTAACCTTAAGAGGAGCTTTGATGTCCGAGAGGTCATTGCTAGAATCGTGGATGGAAGC AGATTCACTGAGTTCAAAGCCTTTTATGGAGACACATTAGTTACAGGATTTGCTCGAATA TTTGGGTACCCAGTAGGTATCGTTGGAAACAACGGAGTTCTCTTTTCTGAATCTGCAAAA AAGGGTACTCACTTTGTCCAGTTATGCTGCCAAAGAAATATTCCTCTGCTGTTCCTTCAA AACATTACTGGATTTATGGTTGGTAGAGAGTATGAAGCTGAAGGAATTGCCAAGGATGGT GCCAAGATGGTGGCCGCTGTGGCCTGTGCCCAAGTGCCTAAGATAACCCTCATCATTGGG GGCTCCTATGGAGCCGGAAACTATGGGATGTGTGGCAGAGCGTATAGCCCAAGATTTCTC TACATTTGGCCAAATGCTCGTATCTCAGTGATGGGAGGAGAGCAGGCAGCCAATGTGTTG GCCACGATAACAAAGGACCAAAGAGCCCGGGAAGGAAAGCAGTTCTCCAGTGCTGATGAA GCGGCTTTAAAAGAGCCCATCATTAAGAAGTTTGAAGAGGAAGGAAACCCTTACTATTCC AGCGCAAGGGTATGGGATGATGGGATCATTGATCCAGCAGACACCAGACTGGTCTTGGGT CTCAGTTTTAGTGCAGCCCTCAACGCACCAATAGAGAAGACTGACTTCGGTATCTTCAGG ATGTAACTGGAATAAAAGGATGTTTTCTG >OriGene 5' read for NM_022132 unedited
NGGGTTCAGAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCTGCAAGG ACCTGAGCTCAGCTTCCGCCCCAGCCAGGGAAGCGGCAGGGGAAAGCACCGGCTCCAGGC CAGCGTGGGCCGCTCTCTCGCTCGGTGCCCGCCGCCATGTGGGCCGTCCTGAGGTTAGCC CTGCGGCCGTGTGCCCGCGCCTCTCCCGCCGGGCCGCGCGCCTATCACGGGGACTCGGTG GCCTCGCTGGGCACCCAGCCGGACTTGGGCTCTGCCCTCTACCAGGAGAACTACAAGCAG ATGAAAGCACTAGTAAATCAGCTCCATGAACGAGTGGAGCATATAAAACTAGGAGGTGGT GAGAAAGCCCGAGCACTTCACATATCAAGAGGAAAACTATTGCCCAGAGAAAGAATTGAC AATCTCATAGACCCAGGGTCTCCATTTCTGGAATTATCCCAGTTTGCAGGTTACCAGTTA TATGACAATGAGGAGGTGCCAGGAGGTGGCATTATTACAGGCATTGGAAGAGTATCAGGA GTAGAATGCATGATTATTGCCAATGATGCCACCGTCAAAGGAGGTGCCTACTACCCAGTG ACTGTGAAAAAACAATTACGGGCCCAAGAAATTGCCATGCAAAACAGGCTCCCCTGCATC TACTTAGTTGATTCGGGAGGAGCATACTTACCTCGACAGCAGATGTGTTTCCAGATCGAG ACCACTTTGGCCGTACATTCTATAATCAGGCAATTATGTCTTCTAAAATATTGCACAGAT CGCAGTGGTCATGGGCTCCTGCACCGCNNAGAGAGCCTATGTGCCTGCCATGGCTGATGA AAACATCATTGTACGCAAGCAGGGTACCATTTTCTTGGCAGGACCCCCCTTGGNNTAAAG CGGCACTGGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_022132 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_022132.3, NP_071415.1 |
| RefSeq Size | 2329 bp |
| RefSeq ORF | 1692 bp |
| Locus ID | 64087 |
| UniProt ID | Q9HCC0 |
| Domains | Carboxyl_trans |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Valine, leucine and isoleucine degradation |
| Gene Summary | This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209488 | MCCC2 (Myc-DDK-tagged)-Human methylcrotonoyl-CoA carboxylase 2 (beta) (MCCC2), nuclear gene encoding mitochondrial protein |
CNY 4,192.00 |
|
| RC209488L2 | Lenti ORF clone of Human methylcrotonoyl-CoA carboxylase 2 (beta) (MCCC2), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 6,592.00 |
|
| RC209488L3 | Lenti ORF clone of Human methylcrotonoyl-CoA carboxylase 2 (beta) (MCCC2), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209488L4 | Lenti ORF clone of Human methylcrotonoyl-CoA carboxylase 2 (beta) (MCCC2), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
| RG209488 | MCCC2 (tGFP-tagged) - Human methylcrotonoyl-CoA carboxylase 2 (beta) (MCCC2), nuclear gene encoding mitochondrial protein |
CNY 5,792.00 |
