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PDPN (NM_006474) Human Untagged Clone
CAT＃: SC125342
PDPN (untagged)-Human podoplanin (PDPN), transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AGGRUS; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125342 sequence for NM_006474 edited (data generated by NextGen Sequencing)
ATGCTGACTCCGCTCGGAAAGTTCTCAACTGCAAAGTTTGCTGTCCGGCTGCCTAGGGTC TGGGAAGCTCGGGCACCCTCCCTCTCCGGGGCTCCTGCTCCCACCCCTCCGGCCCCCCCA CCGTCGCGCTCCTCCAGGCTGGGCCTGTGGCCGCGGTGCTTTTTAATTTTCCCCCAGCTC AGAATCTTGCTGCTCGGCCCCCAGGAGAGCAACAACTCAACGGGAACGATGTGGAAGGTG TCAGCTCTGCTCTTCGTTTTGGGAAGCGCGTCGCTCTGGGTCCTGGCAGAAGGAGCCAGC ACAGGCCAGCCAGAAGATGACACTGAGACTACAGGTTTGGAAGGCGGCGTTGCCATGCCA GGTGCCGAAGATGATGTGGTGACTCCAGGAACCAGCGAAGACCGCTATAAGTCTGGCTTG ACAACTCTGGTGGCAACAAGTGTCAACAGTGTAACAGGCATTCGCATCGAGGATCTGCCA ACTTCAGAAAGCACAGTCCACGCGCAAGAACAAAGTCCAAGCGCCACAGCCTCAAACGTG GCCACCAGTCACTCCACGGAGAAAGTGGATGGAGACACACAGACAACAGTTGAGAAAGAT GGTTTGTCAACAGTGACCCTGGTTGGAATCATAGTTGGGGTCTTACTAGCCATCGGCTTC ATTGGTGGAATCATCGTTGTGGTTATGCGAAAAATGTCGGGAAGGTACTCGCCCTAA Clone variation with respect to NM_006474.4 668 c=>g >OriGene 5' read for NM_006474 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGAGACCACCTTGCG GCCGACCCCGCTCCCCCGCCTCCTCGGGAGAGATAAATGCTGACTCCGCTCGGAAAGTTC TCAACTGCAAAGTTTGCTGTCCGGCTGCCTAGGGTCTGGGAAGCTCGGGCACCCTCCCTC TCCGGGGCTCCTGCTCCCACCCCTCCGGCCCCCCCACCGTCGCGCTCCTCCAGGCTGGGC CTGTGGCCGCGGTGCTTTTTAATTTTCCCCCAGCTCAGAATCTTGCTGCTCGGCCCCCAG GAGAGCAACAACTCAACGGGAACGATGTGGAAGGTGTCAGCTCTGCTCTTCGTTTTGGGA AGCGCGTCGCTCTGGGTCCTGGCAGAAAGAGCCAGCACAGGCCAGCCAGAAGATGACACT GAGACTACAGGTTTGGAAGGCGGCGTTGCCATGCCAGGTGCCGAAGATGATGTGGTGACT CCAGGAACCAGCGAAGACCGCTATAAGTCTGGCTTGACAACTCTGGTGGCAACAAGTGTC AACAGTGTAACAGGCATTCGCATCGAGGATCTGCCAACTTCAGAAAGCACAGTCCACGCG CAAGAACAAAGTCCAAGCGCCACAGCCTCAAACGTGGCCACCAGTCACTCCACGGAGAAA GTGGATGGAGACACACAGACCCACAGTGAGAAAGATGGTTTGTCAACAGTGACCCTGGTT GGAATCATAGCTGGNGTCTTACTAGCCATCGGCTTTCATGGNTGGAATCATCCGNTGTGG TTATGCGAAAAAATGTCGGGAAGGTACTCGCCCTAAAAAGCTGAAGGGTTACCCCCTGCT GCCAACGTGCTTAAAAAAGAACGTTTTTGACTCTGGGCCCTGTCCCTGGACTCGGGGAAA AGAAGACCCCTGAAACC >OriGene 3' read for NM_006474 unedited
AAACTTATCCTTTGTTTTCTTTGNAAAACATGTNCTACACATGCATTGNANCACCAACAC AGGCTGCTGACCAAGTAAACCCACAGTCCTGTCCCCGCAGGCACTGGGTCCAGTGTATGA CTTGGGGTGGACTGTTATTTTTCACAGTGAGGGGGGGAAGGATAGGAAAGAAAAGATGGC CATTATCCCAACTCCTGTTCAGGAATCTGAACAATGAAAGTTATTTAAACTCATCCAGCT CTTCTCATTCCCCTTCTCTCAATCAGCTGGTGTTCAAATATGGAATCTGAGGCCGAGCGC AGTGGCACACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTC AAGAGATAGAGATCATCCTCGCCGATACGGTGAAACCCCATCTCTACTAAAAATACAAAA ATTGGCCGGGTGTGGTGGTAGGAACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGA GAATTGCTTTTTGACATCCTGACACATGTATAATTGCCGGGAGGCAGAGTTGCAGACTAC GTTTCACACACACACACAAAAAAAATGGAATCTGAGCTGGTGGGGCCAGCTGGATTTGGG AACACACAGACACACTGTTTAAAATAACATCCAGACATCATTGCANANAATGGGAGGAAT GGGCTGTGCTTCCGAATGATAGTTTACTTNNTCCTGTTTTATGAATGCTTTACAATTTAG AGGATACCAGAGTTGCACANCCCGCCTCATGACAGAGCATCTGCTCAATGTTAAAACTTT GTTTAAGAAAAAAAAAAAAATCCCATGGGTTTCTGGGAAAAAAATTGCCCGCCTGGATGG GGCCTGACCAAATGACCCCTTGGGCCTCCTTATTTTGTTCTTTTCCCCGGACCCCCAAAA TTTTTCGGTTTCCATAAGAGCCGGGATTTTTCCTTTTTAAAAAGGGTTTGTCCAAACCTC TTTAATAAAAACTTCACATTGTTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006474 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006474.4, NP_006465.3 |
| RefSeq Size | 2828 bp |
| RefSeq ORF | 717 bp |
| Locus ID | 10630 |
| UniProt ID | Q86YL7 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Podoplanin is involved in the prognosis of head and neck squamous cell carcinoma through interaction with VEGF-C
,Kim, HY;Rha, KS;Shim, GA;Kim, JH;Kim, JM;Huang, SM;Koo, BS;,
Oncol. Rep.
,PubMed ID 26081937
[PDPN]
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Tumor Lymphangiogenesis and Metastasis to Lymph Nodes Induced by Cancer Cell Expression of Podoplanin
,Leah N. Cueni, Ivan Hegyi, Jay W. Shin, Andrea Albinger-Hegyi, Silke Gruber, Rainer Kunstfeld, Holger Moch, and Michael Detmar,
Am. J. Pathol., Aug 2010; 177: 1004 - 1016
[PDPN]
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Up-Regulation of the Lymphatic Marker Podoplanin, a Mucin-Type Transmembrane Glycoprotein, in Human Squamous Cell Carcinomas and Germ Cell Tumors
,Vivien Schacht, Soheil S. Dadras, Louise A. Johnson, David G. Jackson, Young-Kwon Hong, and Michael Detmar,
Am. J. Pathol. 2005 Mar;166(3):913-21.
[PDPN]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224811 | PDPN (Myc-DDK-tagged)-Human podoplanin (PDPN), transcript variant 1 |
CNY 2,400.00 |
|
| RC224811L1 | Lenti ORF clone of Human podoplanin (PDPN), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC224811L2 | Lenti ORF clone of Human podoplanin (PDPN), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC224811L3 | Lenti ORF clone of Human podoplanin (PDPN), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224811L4 | Lenti ORF clone of Human podoplanin (PDPN), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG224811 | PDPN (tGFP-tagged) - Human podoplanin (PDPN), transcript variant 1 |
CNY 4,000.00 |
