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Histone H2A.X (H2AFX) (NM_002105) Human Untagged Clone
CAT＃: SC125294
H2AFX (untagged)-Human H2A histone family, member X (H2AFX)
CNY 1,200.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 4,070.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | H2A.X; H2A/X; H2AFX |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125294 sequence for NM_002105 edited (data generated by NextGen Sequencing)
ATGTCGGGCCGCGGCAAGACTGGCGGCAAGGCCCGCGCCAAGGCCAAGTCGCGCTCGTCG CGCGCCGGCCTCCAGTTCCCAGTGGGCCGTGTACACCGGCTGCTGCGGAAGGGCCACTAC GCCGAGCGCGTTGGCGCCGGCGCGCCAGTGTACCTGGCGGCAGTGCTGGAGTACCTCACC GCTGAGATCCTGGAGCTGGCGGGCAATGCGGCCCGCGACAACAAGAAGACGCGAATCATC CCCCGCCACCTGCAGCTGGCCATCCGCAACGACGAGGAGCTCAACAAGCTGCTGGGCGGC GTGACGATCGCCCAGGGAGGCGTCCTGCCCAACATCCAGGCCGTGCTGCTGCCCAAGAAG ACCAGCGCCACCGTGGGGCCGAAGGCGCCCTCGGGCGGCAAGAAGGCCACCCAGGCCTCC CAGGAGTACTAA Clone variation with respect to NM_002105.2 >OriGene 5' read for NM_002105 unedited
NCCCGTTCAGATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGTCTGTT CTAGTGTTTGAGCCGTCGTGCTTCACCGGTCTACCTCGCTAGCATGTCGGGCCGCGGCAA GACTGGCGGCAAGGCCCGCGCCAAGGCCAAGTCGCGCTCGTCGCGCGCCGGCCTCCAGTT CCCAGTGGGCCGTGTACACCGGCTGCTGCGGAAGGGCCACTACGCCGAGCGCGTTGGCGC CGGCGCGCCAGTGTACCTGGCGGCAGTGCTGGAGTACCTCACCGCTGAGATCCTGGAGCT GGCGGGCAATGCGGCCCGCGACAACAAGAAGACGCGAATCATCCCCCGCCACCTGCAGCT GGCCATCCGCAACGACGAGGAGCTCAACAAGCTGCTGGGCGGCGTGACGATCGCCCAGGG AGGCGTCCTGCCCAACATCCAGGCCGTGCTGCTGCCCAAGAAGACCAGCGCCACCGTGGG GCCGAAGGCGCCCTCGGGCGGCAAGAAGGCCACCCAGGCCTCCCAGGAGTACTAAGAGGG CCCGCGCCGCGGCCGGCCGCCAGGCCTCCCCATGCCACCACAAAGGCCCTTTTAAGGGCC ACCACCGCCCTCATGGAAAGAGCTGAGCCGCTTCAGACTGCGGGGCAAGCGGGCCCGGNN TTCCTTTTCCCTTCCCCTTCCCTCGCCCGNCTTCGNCGNCCGGNCTNNGAGTCCCGCCCG CCCCCGCTCCCGTNCCGCACCGCCTGCCGNNGTCNGNCTCGGGCCCTGCCCTGTCCGCCG TNCGCCTTCGNGNTAGGGTCGGGCCTTTCCGATGCNGCTTTGGCGCTCTTCGGGACCTNC GTGGGCGCGAAGACCACCCTGCCGGGGGGGAAGGGCCGNGGNGCCNNACCTGNCCGNCCT CGGNGTTCGTGACTCAACCGCCCATNCCGAGTGCTAAGGGGCTGCGGGGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002105 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002105.1, NP_002096.1 |
| RefSeq Size | 1585 bp |
| RefSeq ORF | 432 bp |
| Locus ID | 3014 |
| UniProt ID | P16104 |
| Domains | H2A, histone |
| Protein Families | Druggable Genome |
| Protein Pathways | Systemic lupus erythematosus |
| Gene Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells
,null,
Neuro-Oncology
,PubMed ID 22573309
[H2AX]
|
|
uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells
,Rama Rao Malla, Sreelatha Gopinath, Kiranmai Alapati, Bharathi Gorantla, Christopher S. Gondi, and Jasti S. Rao,
Neuro Oncology, Jun 2012; 14: 745 - 760.
[H2AX]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201434 | H2AFX (Myc-DDK-tagged)-Human H2A histone family, member X (H2AFX) |
CNY 1,200.00 |
|
| RC201434L1 | Lenti ORF clone of Human H2A histone family, member X (H2AFX), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC201434L2 | Lenti ORF clone of Human H2A histone family, member X (H2AFX), mGFP tagged |
CNY 5,890.00 |
|
| RC201434L3 | Lenti ORF clone of Human H2A histone family, member X (H2AFX), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201434L4 | Lenti ORF clone of Human H2A histone family, member X (H2AFX), mGFP tagged |
CNY 5,890.00 |
|
| RG201434 | H2AFX (tGFP-tagged) - Human H2A histone family, member X (H2AFX) |
CNY 2,800.00 |
|
| SC320322 | H2AFX (untagged)-Human H2A histone family, member X (H2AFX) |
CNY 1,200.00 |
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