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VCP (NM_007126) Human Untagged Clone
CAT＃: SC125280
VCP (untagged)-Human valosin containing protein (VCP)
CNY 5,912.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDC48; FTDALS6; p97; TERA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125280 sequence for NM_007126 edited (data generated by NextGen Sequencing)
ATGGCTTCTGGAGCCGATTCAAAAGGTGATGACCTATCAACAGCCATTCTCAAACAGAAG AACCGTCCCAATCGGTTAATTGTTGATGAAGCCATCAATGAGGACAACAGTGTGGTGTCC TTGTCCCAGCCCAAGATGGATGAATTGCAGTTGTTCCGAGGTGACACAGTGTTGCTGAAA GGAAAGAAGAGACGAGAAGCTGTTTGCATCGTCCTTTCTGATGATACTTGTTCTGATGAG AAGATTCGGATGAATAGAGTTGTTCGGAATAACCTTCGTGTACGCCTAGGGGATGTCATC AGCATCCAGCCATGCCCTGATGTGAAGTACGGCAAACGTATCCATGTGCTGCCCATTGAT GACACAGTGGAAGGCATTACTGGTAATCTCTTCGAGGTATACCTTAAGCCGTACTTCCTG GAAGCGTATCGACCCATCCGGAAAGGAGACATTTTTCTTGTCCGTGGTGGGATGCGTGCT GTGGAGTTCAAAGTGGTGGAAACAGATCCTAGCCCTTATTGCATTGTTGCTCCAGACACA GTGATCCACTGCGAAGGGGAGCCTATCAAACGAGAGGATGAGGAAGAGTCCTTGAATGAA GTAGGGTATGATGACATTGGTGGCTGCAGGAAGCAGCTAGCTCAGATAAAGGAGATGGTG GAACTGCCCCTGAGACATCCTGCCCTCTTTAAGGCAATTGGTGTGAAGCCTCCTAGAGGA ATCCTGCTTTACGGACCTCCTGGAACAGGAAAGACCCTGATTGCTCGAGCTGTAGCAAAT GAGACTGGAGCCTTCTTCTTCTTGATCAATGGTCCTGAGATCATGAGCAAATTGGCTGGT GAGTCTGAGAGCAACCTTCGTAAAGCCTTTGAGGAGGCTGAGAAGAATGCTCCTGCCATC ATCTTCATTGATGAGCTAGATGCCATCGCTCCCAAAAGAGAGAAAACTCATGGCGAGGTG GAGCGGCGCATTGTATCACAGTTGTTGACCCTCATGGATGGCCTAAAGCAGAGGGCACAT GTGATTGTTATGGCAGCAACCAACAGACCCAACAGCATTGACCCAGCTCTACGGCGATTT GGTCGCTTTGACAGGGAGGTAGATATTGGAATTCCTGATGCTACAGGACGCTTAGAGATT CTTCAGATCCATACCAAGAACATGAAGCTGGCAGATGATGTGGACCTGGAACAGGTAGCC AATGAGACTCACGGGCATGTGGGTGCTGACTTAGCAGCCCTGTGCTCAGAGGCTGCTCTG CAAGCCATCCGCAAGAAGATGGATCTCATTGACCTAGAGGATGAGACCATTGATGCCGAG GTCATGAACTCTCTAGCAGTTACTATGGATGACTTCCGGTGGGCCTTGAGCCAGAGTAAC CCATCAGCACTGCGGGAAACCGTGGTAGAGGTGCCACAGGTAACCTGGGAAGACATCGGG GGCCTAGAGGATGTCAAACGTGAGCTACAGGAGCTGGTCCAGTATCCTGTGGAGCACCCA GACAAATTCCTGAAGTTTGGCATGACACCTTCCAAGGGAGTTCTGTTCTATGGACCTCCT GGCTGTGGGAAAACTTTGTTGGCCAAAGCCATTGCTAATGAATGCCAGGCCAACTTCATC TCCATCAAGGGTCCTGAGCTGCTCACCATGTGGTTTGGGGAGTCTGAGGCCAATGTCAGA GAAATCTTTGACAAGGCCCGCCAAGCTGCCCCCTGTGTGCTATTCTTTGATGAGCTGGAT TCGATTGCCAAGGCTCGTGGAGGTAACATTGGAGATGGTGGTGGGGCTGCTGACCGAGTC ATCAACCAGATCCTGACAGAAATGGATGGCATGTCCACAAAAAAAAATGTGTTCATCATT GGCGCTACCAACCGGCCTGACATCATTGATCCTGCCATCCTCAGACCTGGCCGTCTTGAT CAGCTCATCTACATCCCACTTCCTGATGAGAAGTCCCGTGTTGCCATCCTCAAGGCTAAC CTGCGCAAGTCCCCAGTTGCCAAGGATGTGGACTTGGAGTTCCTGGCTAAAATGACTAAT GGCTTCTCTGGAGCTGACCTGACAGAGATTTGCCAGCGTGCTTGCAAGCTGGCCATCCGT GAATCCATCGAGAGTGAGATTAGGCGAGAACGAGAGAGGCAGACAAACCCATCAGCCATG GAGGTAGAAGAGGATGATCCAGTGCCTGAGATCCGTCGAGATCACTTTGAAGAAGCCATG CGCTTTGCGCGCCGTTCTGTCAGTGACAATGACATTCGGAAGTATGAGATGTTTGCCCAG ACCCTTCAGCAGAGTCGGGGCTTTGGCAGCTTCAGATTCCCTTCAGGGAACCAGGGTGGA GCTGGCCCCAGTCAGGGCAGTGGAGGCGGCACAGGTGGCAGTGTATACACAGAAGACAAT GATGATGACCTGTATGGCTAA Clone variation with respect to NM_007126.3 >OriGene 5' read for NM_007126 unedited
NNGGGTCAGATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGGTCGCTG CCGCTGCCGCTGCCACTGCCACTGCCACCTCGCGGATCAGGAGCCAGCGTTGTTCGCCCG ACGCCTCGCTGCCGGTGGGAGGAAGCGAGAGGGAAGCCGCTTGCGGGTTTGTCGCCGCTG CTCGCCCACCGCCTGGAAGAGCCGAGCCCCGGCCCAGTCGGTCGCTTGCCACCGCTCGTA GCCGTTACCCGCGGGCCGCCACAGCCGCCGGCCGGGAGAGGCGCGCGCCATGGCTTCTGG AGCCGATTCAAAAGGTGATGACCTATCAACAGCCATTCTCAAACAGAAGAACCGTCCCAA TCGGTTAATTGTTGATGAAGCCATCAATGAGGACAACAGTGTGGTGTCCTTGTCCCAGCC CAAGATGGATGAATTGCAGTTGTTCCGAGGTGACACAGTGTTGCTGAAAGGAAAGAAGAG ACGAGAAGCTGTTTGCATCGTCCTTTCTGATGATACTTGTTCTGATGAGAAGATTCGGAT GAATAGAGTTGTTCGGAATAACCTTCGTGTACGCCTAGGGGATGTCATCAGCATCCAGCC ATGCCCTGATGTGAAGTACGGCAAACGTATCCATGTGCTGCCCATTGATGACACAGTGGA AGGCATTACTGGTAATCTCTTCGAGGTATACCTTAAGCCGTACTTCCTGGAAGCGTATCG ACCCATCCGGAAAGGAGACATTNTTCTTGTCCGTGGTGGGATGCGTGCTGTGGAGTTCAA AGTGGTGGAAACAGATCCTAGCCCTTATTGCATTGNTGCTCCGACACAGTGATCACTGCG AAGGNGAGCCTATCANACGAGAGATGAAGGANAGTCCTTGATGAANTAGGTATGATGACA TGGNTGGT >OriGene 3' read for NM_007126 unedited
NGGGCATTGNNAGTCGCTTTTCATTTATCGCTTTTGTTTTGTATTTTTGGCAACAGAAAA CCCCCTGTCCANAGTCAGACTGTAGCTGAACTGTTCAGACTGGAGAATGGAGCAGGCTGT GGGCGCACCCCTGGTCCCTCTCCTGGGCAAGCGCCCCCACCCCCAGGGAACAAGGTCCAG GCAGGCCAGCTCACTGCACGCTGGCCACCACCACTTAGCCATACAGGTCATCATCATTGT CTTCTGTGTATACACTGCCACCTGTGCCGCCTCCACTGCCCTGACTGGGGCCAGCTCCAC CCTGGTTCCCTGAAGGGAATCTGAAGCTGCCAAAGCCCCGACTCTGCTGAAGGGTCTGGG CAAACATCTCATACTTCCGAATGTCATTGTCACTGACAGAACGGCGCGCAAAGCGCATGG CTTCTTCAAAGTGATCTCGACGGATCTCAGGCACTGGATCATCCTCTTCTACCTCCATGG CTGATGGGTTTGTCTGCCTCTCTCGTTCTCGCCTAATCTCACTCTCGATGGATTCACGGA TGGCCAGCTTGCAAGCACGCTGGCAAATCTCTGTCAGGTCAGCTCCAGAGAAGCCATTAG TCATTTTAGCCAGGAACTCCAAGTCCACATCCTTGGCAACTGGGGACTTGCGCANGTTAG CCTTGAGGATGGGGCACACGGACTTCTCATCANGAAGTGGGATGTAGATGAGCTGATCAA GACNGCCAGGTCTGANGATGGCAGGATCAATGATGTCAGGCCCGTTGGTAGCGCCCATGA TGAACACATTTTTTTTTGTGGACATGCCATCCATTTNCTGTCAGGATCTGGNTTGATGAC TCGTCAGCAGCCCCACCACATCTTCAATGTACCCTCACGAGCCTTGGGGCATCGATCCAG CTCATCAAAGATAGCCCACAAGGGGCAGCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007126 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007126.2, NP_009057.1 |
| RefSeq Size | 3198 bp |
| RefSeq ORF | 2421 bp |
| Locus ID | 7415 |
| UniProt ID | P55072 |
| Domains | cdc48_N, AAA, AAA |
| Gene Summary | This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone
,Sara K. Custer, Manuela Neumann, Hongbo Lu, Alexander C. Wright, and J. Paul Taylor,
Hum. Mol. Genet., May 2010; 19: 1741 - 1755
[VCP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211130 | VCP (Myc-DDK-tagged)-Human valosin containing protein (VCP) |
CNY 5,904.00 |
|
| RC211130L1 | Lenti ORF clone of Human valosin containing protein (VCP), Myc-DDK-tagged |
CNY 8,304.00 |
|
| RC211130L2 | Lenti ORF clone of Human valosin containing protein (VCP), mGFP tagged |
CNY 5,890.00 |
|
| RC211130L3 | Lenti ORF clone of Human valosin containing protein (VCP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211130L4 | Lenti ORF clone of Human valosin containing protein (VCP), mGFP tagged |
CNY 8,304.00 |
|
| RG211130 | VCP (tGFP-tagged) - Human valosin containing protein (VCP) |
CNY 7,504.00 |
