Cytohesin 2 (CYTH2) (NM_004228) Human Untagged Clone

CAT#: SC124671

CYTH2 (untagged)-Human cytohesin 2 (CYTH2), transcript variant 2



  "NM_004228" in other vectors (4)

CNY 3,656.00

CNY 7,220.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
CYTH2 mouse monoclonal antibody,clone OTI4D9
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ARNO; CTS18; CTS18.1; cytohesin-2; PSCD2; PSCD2L; SEC7L; Sec7p-L; Sec7p-like
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_004228, the custom clone sequence may differ by one or more nucleotides


ATGGAGGACGGCGTCTATGAACCCCCAGACCTGACTCCGGAGGAGCGGATGGAGCTGGAGAACATCCGGC
GGCGGAAGCAGGAGCTGCTGGTGGAGATTCAGCGCCTGCGGGAGGAGCTCAGTGAAGCCATGAGCGAGGT
GGAGGGGCTGGAGGCCAATGAGGGCAGTAAGACCTTGCAACGGAACCGGAAGATGGCAATGGGCAGGAAG
AAGTTCAACATGGACCCCAAGAAGGGGATCCAGTTCTTGGTGGAGAATGAACTGCTGCAGAACACACCCG
AGGAGATCGCCCGCTTCCTGTACAAGGGCGAGGGGCTGAACAAGACAGCCATCGGGGACTACCTGGGGGA
GAGGGAAGAACTGAACCTGGCAGTGCTCCATGCTTTTGTGGATCTGCATGAGTTCACCGACCTCAATCTG
GTGCAGGCCCTCAGGCAGTTTCTATGGAGCTTTCGCCTACCCGGAGAGGCCCAGAAAATTGACCGGATGA
TGGAGGCCTTCGCCCAGCGATACTGCCTGTGCAACCCTGGGGTTTTCCAGTCCACAGACACGTGCTATGT
GCTGTCCTTCGCCGTCATCATGCTCAACACCAGTCTCCACAATCCCAATGTCCGGGACAAGCCGGGCCTG
GAGCGCTTTGTGGCCATGAACCGGGGCATCAACGAGGGCGGGGACCTGCCTGAGGAGCTGCTCAGGAACC
TGTACGACAGCATCCGAAATGAGCCCTTCAAGATTCCTGAGGATGACGGGAATGACCTGACCCACACCTT
CTTCAACCCGGACCGGGAGGGCTGGCTCCTGAAGCTGGGGGGCCGGGTGAAGACGTGGAAGCGGCGCTGG
TTTATCCTCACAGACAACTGCCTCTACTACTTTGAGTACACCACGGACAAGGAGCCCCGAGGAATCATCC
CCCTGGAGAATCTGAGCATCCGAGAGGTGGACGACCCCCGGAAACCGAACTGCTTTGAACTTTACATCCC
CAACAACAAGGGGCAGCTCATCAAAGCCTGCAAAACTGAGGCGGACGGCCGAGTGGTGGAGGGAAACCAC
ATGGTGTACCGGATCTCGGCCCCCACGCAGGAGGAGAAGGACGAGTGGATCAAGTCCATCCAGGCGGCTG
TGAGTGTGGACCCCTTCTATGAGATGCTGGCAGCGAGAAAGAAGCGGATTTCAGTCAAGAAGAAGCAGGA
GCAGCCCTGA


>OriGene 5' read for NM_004228 unedited
CGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACCAGGAGGAGGCGG
CGGTGGCTCCCGGGGCGTTTGAGCGGGCTCACCCGAGCCCGCGGGCCAACGCGGATCCAG
GCCCGACTGGCGGGACCGCCCCGGATTCCCCGCGGGCCTTCCTAGCCGCCATGGAGGACG
GCGTCTATGAACCCCCAGACCTGACTCCGGAGGAGCGGATGGAGCTGGAGAACATCCGGC
GGCGGAAGCAGGAGCTGCTGGTGGAGATTCAGCGCCTGCGGGAGGAGCTCAGTGAAGCCA
TGAGCGAGGTGGAGGGGCTGGAGGCCAATGAGGGCAGTAAGACCTTGCAACGGAACCGGA
AGATGGCAATGGGCAGGAAGAAGTTCAACATGGACCCCAAGAAGGGGATCCAGTTCTTGG
TGGAGAATGAACTGCTGCAGAACACACCCGAGGAGATCGCCCGCTTCCTGTACAAGGGCG
AGGGGCTGAACAAGACAGCCATCGGGGCCTACCCTGGGGGAGAGGGAAGAACTGAACCTG
GCAGTGCTCCATGCTTTTGTGGATCTGCATGAGTTCACCGACCTCAATCTGGTGCAGGCC
CTCANGCAGTTTCTATGGAGNCTTCGCCTACCCGGAGAGGCCCCAGAAATTGACCGGATG
ATGGNAGGCCTTCGCCCAGCGATACTGCCTGTGCACCCTGGGGGTTTTCAGTCACAGACC
GTGCTTTGTGCTGTCTTCGCCTCATATGCTCACACCGTCTCACATCCCATGTCCGGACAG
GCGGCCTGAGCGCTTTGTGGCATGACCGGGCATCACGAGGCCGGGACTGNCTGAGAGCTG
TCAGGAACCTGTCACAGATCGAATGAGCCTCAGATCTGAGGAGACGGGAAGACTGACCAC
ACTTTTAACGCCGGAAGGTGTCCTAAATGGAGGGGGCCCCGGAAAAAGGAAG
Restriction Sites NotI-NotI     
ACCN NM_004228
Insert Size 1800 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_004228.4, NP_004219.2
RefSeq Size 4622 bp
RefSeq ORF 1200 bp
Locus ID 9266
UniProt ID Q99418
Protein Families Druggable Genome
Gene Summary The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Transcript Variant: This variant (2) lacks a 3-nucleotide exon in the PH domain region, compared to variant 1. This results in a protein (isoform 2) missing a single glycine residue, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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