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Integrin beta 4 binding protein (EIF6) (NM_181468) Human Untagged Clone
CAT＃: SC124305
EIF6 (untagged)-Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | b(2)gcn; CAB; eIF-6; EIF3A; ITGB4BP; p27(BBP); p27BBP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_181468, the custom clone sequence may differ by one or more nucleotides
ATGGCGGTCCGAGCTTCGTTCGAGAACAACTGTGAGATCGGCTGCTTTGCCAAGCTCACCAACACCTACT GTCTGGTAGCGATCGGAGGCTCAGAGAACTTCTACAGTGTGTTCGAGGGCGAGCTCTCCGATACCATCCC CGTGGTGCACGCGTCTATCGCCGGCTGCCGCATCATCGGGCGCATGTGTGTGGGGAACAGGCACGGTCTC CTGGTACCCAACAATACCACCGACCAGGAGCTGCAACACATTCGCAACAGCCTCCCAGACACAGTGCAGA TTAGGCGGGTGGAGGAGCGGCTCTCAGCCTTGGGCAATGTCACCACCTGCAATGACTACGTGGCCTTGGT CCACCCAGACTTGGACAGGGAGACAGAAGAAATTCTGGCAGATGTGCTCAAGGTGGAAGTCTTCAGACAG ACAGTGGCCGACCAGGTGCTAGTAGGAAGCTACTGTGTCTTCAGCAATCAGGGAGGGCTGGTGCATCCCA AGACTTCAATTGAAGACCAGGATGAGCTGTCCTCTCTTCTTCAAGTCCCCCTTGTGGCGGGGACTGTGAA CCGAGGCAGTGAGGTGATTGCTGCTGGGATGGTGGTGAATGACTGGTGTGCCTTCTGTGGCCTGGACACA ACCAGCACAGAGCTGTCAGTGGTGGAGAGTGTCTTCAAGCTGAATGAAGCCCAGCCTAGCACCATTGCCA CCAGCATGCGGGATTCCCTCATTGACAGCCTCACCTGA >OriGene 5' read for NM_181468 unedited
TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGAGGGACGGAGGC CGGGATACTTGGGAAAGGATCCGCCGGCCTTGAACTCCCGCCTCCGCCGCCCCTAGGCCT CATGGCGGTCCGAGCTTCGTTCGAGAACAACTGTGAGATCGGCTGCTTTGCCAAGCTCAC CAACACCTACTGTCTGGTAGCGATCGGAGGCTCAGAGAACTTCTACAGTGTGTTCGAGGG CGAGCTCTCCGATACCATCCCCGTGGTGCACGCGTCTATCGCCGGCTGCCGCATCATCGG GCGCATGTGTGTGGGGAACAGGCACGGTCTCCTGGTACCCAACAATACCACCGACCAGGA GCTGCAACACATTCGCAACAGCCTCCCAGACACAGTGCAGATTAGGCGGGTGGAGGAGCG GCTCTCAGCCTTGGGCAATGTCACCACCTGCAATGACTACGTGGCCTTGGTCCACCCAGA CTTGGACAGGGAGACAGAAGAAATTCTGGCAGATGTGCTCAAGGTGGAAGTCTTCAGACA GACAGTGGCCGACCAGGTGCTAGTAGGAAGCTACTGTGTCTTCAGCAATCAGGGAGGGCT GGTGCATCCCAAGACTTCAATTGAAGACCAGGATGAGCTGTCCTCTCTTCTTCAAGTCCC CCTTGTGGCGGNGACTGTGAACCGANGCAGTGAGGTGATTGCTGCTGGGATGGTGGTGAA TGACTGGTGTGCCTTCTGTGGCCTGGACACNACCAGCACANAGCTGTCAGTGGTGGAGAG TGTCTTCAAGCTGAATGAAGCCCAGNCCTACACCANGCCACCAGCATGCGGGGATTNCCT CATGACAGCCTCACCTGAGTCACCTTCCAGNNTGTCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_181468 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_181468.1, NP_852133.1 |
| RefSeq Size | 1259 bp |
| RefSeq ORF | 738 bp |
| Locus ID | 3692 |
| UniProt ID | P56537 |
| Protein Families | Druggable Genome |
| Gene Summary | Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 6 all encode isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220391 | EIF6 (Myc-DDK-tagged)-Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2 |
CNY 2,400.00 |
|
| RC220391L1 | Lenti ORF clone of Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC220391L2 | Lenti ORF clone of Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC220391L3 | Lenti ORF clone of Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC220391L4 | Lenti ORF clone of Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG220391 | EIF6 (tGFP-tagged) - Human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2 |
CNY 4,370.00 |
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