SP110 (NM_080424) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	IFI41; IFI75; IPR1; VODI
Vector	pCMV6-XL4
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_080424, the custom clone sequence may differ by one or more nucleotides ATGTTCACCATGACAAGAGCCATGGAAGAGGCTCTTTTTCAGCACTTCATGCACCAGAAGCTGGGGATCG CCTATGCCATACACAAGCCATTTCCCTTCTTTGAAGGCCTCCTAGACAACTCCATCATCACTAAGAGAAT GTACATGGAATCTCTGGAAGCCTGTAGAAATTTGATCCCTGTATCCAGAGTGGTGCACAACATTCTCACC CAACTGGAGAGGACTTTTAACCTGTCTCTTCTGGTGACATTGTTCAGTCAAATTAACCTGCGTGAATATC CCAATCTGGTGACGATTTACAGAAGCTTCAAACGTGTTGGTGCTTCCTATGAACGGCAGAGCAGAGACAC ACCAATCCTACTTGAAGCCCCAACTGGCCTAGCAGAAGGAAGCTCCCTCCATACCCCACTGGCGCTGCCC CCACCACAACCCCCTCAACCAAGCTGTTCACCCTGTGCGCCAAGAGTCAGTGAGCCTGGAACATCCTCCC AGCAAAGCGATGAGATCCTGAGTGAGTCGCCCAGCCCATCTGACCCTGTCCTGCCTCTCCCTGCACTCAT CCAGGAAGGAAGAAGCACTTCAGTGACCAATGACAAGTTAACATCCAAAATGAATGCGGAAGAAGACTCA GAAGAGATGCCCAGCCTCCTCACTAGCACTGTGCAAGTGGCCAGTGACAACCTGATCCCCCAAATAAGAG ATAAAGAAGACCCTCAAGAGATGCCCCACTCTCCCTTGGGCTCTATGCCAGAGATAAGAGATAATTCTCC AGAACCAAATGACCCAGAAGAGCCCCAGGAGGTGTCCAGCACACCTTCAGACAAGAAAGGAAAGAAAAGA AAAAGATGTATCTGGTCAACTCCAAAAAGGAGACATAAGAAAAAAAGCCTCCCAGGAGGGACAGCCTCAT CTAGACACGGAATCCAAAAGAAGCTCAAAAGGGTGGATCAGGTTCCTCAAAAGAAAGATGACTCAACTTG TAACTCCACGGTAGAGACAAGGGCCCAAAAGGCGAGAACTGAATGTGCCCGAAAGTCGAGATCAGAGGAG ATCATTGATGGCACTTCAGAAATGAATGAAGGAAAGAGGTCCCAGAAGACGCCTAGTACACCACGAAGGG TCACACAAGGGGCAGCCTCACCTGGGCATGGCATCCAAGAGAAGCTCCAAGTGGTGGATAAGGTGACTCA AAGGAAAGACGACTCAACCTGGAACTCAGAGGTCATGATGAGGGTCCAAAAGGCAAGAACTAAATGTGCC CGAAAGTCCAGATCGAAAGAAAAGAAAAAGGAGAAAGATATCTGTTCAAGCTCAAAAAGGAGATTTCAGA AAAATATTCACCGAAGAGGAAAACCCAAAAGTGACACTGTGGATTTTCACTGTTCTAAGCTCCCCGTGAC CTGTGGTGAGGCGAAAGGGATTTTATATAAGAAGAAAATGAAACACGGATCCTCAGTGAAGTGCATTCGG AATGAGGATGGAACTTGGTTAACACCAAATGAATTTGAAGTCGAAGGAAAAGGAAGGAACGCAAAGAACT GGAAACGGAATATACGTTGTGAAGGAATGACCCTAGGAGAGCTGCTGAAGCGGAAAAACTCGGATGAATG CGAGGTGTGCTGTCAAGGGGGACAACTTCTCTGCTGCGGTACTTGTCCACGAGTCTTCCATGAGGACTGT CACATCCCCCCTGTGGAAGCCAAGAGGATGCTGTGGAGTTGCACCTTCTGCAGGATGAAGAGGTCTTCAG GAAGCCAACAGTGCCATCATGTATCTAAGACCCTGGAGAGGCAGATGCAGCCTCAGGACCAGCTGAAATG TGAGTTCCTCCTCTTGAAGGCCTACTGTCATCCACAAAGCTCCTTTTTTACGGGCATCCCATTTAATATT CGAGATTACGGTGAGCCCTTTCAGGAAGCAATGTGGTTGGACCTGGTTAAGGAAAGGCTGATTACGGAAA TGTACACGGTGGCATGGTTTGTGCGAGACATGCGCCTGATGTTTCGCAACCATAAAACATTTTACAAGGC TTCTGACTTTGGCCAGGTAGGACTTGACTTAGAGGCAGAATTTGAAAAAGATCTCAAAGACGTGCTCGGT TTTCATGAAGCCAATGACGGCGGTTTCTGGACTCTTCCTTGA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for NM_080424 unedited GTGCTAGCATTTGTCAATACTACTTCATCTTAGGNCGAGCCGCGNAATTNCGAGCACGAA GGTAACCTCTCCCAATCTTAGAGAGTGATCCCTGTCCCAGCCCCTGGAAAGGGCAGGAAC GACAAACTCAAAGTCCAGGATGTTCACCATGACAAGAGCCATGGAAGAGGCTCTTTTTCA GCACTTCATGCACCAGAAGCTGGGGATCGCCTATGCCATACACAAGCCATTTCCCTTCTT TGAAGGCCTCCTATACAACTCCATCATCACTAAGAGAATGTACATGGAATCTCTGGAAGC CTGTAGAAATTTGATCCCTGTATCCAGAGTGGTGCACAACATTCTCACCCAACTGGAGAG GACTTTTAACCTGTCTCTTCTGGTGACATTGTTCAGTCAAATTAACCTGCGTGAATATCC CAATCTGGTGACGATTTACAGAAGCTTCAAACGTGTTGGTGCTTCCTATGAACGGCAGAG CAGAGACACACCAATCCTACTTGAAGCCCCAACTGGCCTATCAGAAAGAAGCTCCCTCCA TACCCCACTGGCGCTGCCCCCACCACAACCCCCTCAACCAAGCTGTTCACCCTGTGCGCC AAGAGTCAGTGAGCCTGGAACATCCTCCCAGCAAAGCGATGAGATCCTGAGTGAGTCGCC CATCCCATCTGACCCTGTCCTGCCTCTCCCTGCACTCATCCAGGAAAGAAGAAGCACTTC AGTGACCAATGACAAGTTAACATCCAAAATGAATGTGGAAGAAGACTCAGAAGATAGCCC AGCCTCCTCACTAGCACTGTGCAAGTGGCCAGTGACAACCTGATCCCCCNAATAGAGATA AAGAAGACCTCAAGAGATGCCCACTCTCCCTTGGGCTCTATCCAGAGATAGAGATATTCT NCAAACCAAATGACCATATATCCCAGNAGTGTCCA 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for NM_080424 unedited TTGTCCATGGAATGGCAACTTCCAGGTCCAGGNAAAGCATTGGGGTAGGGGTCACAGGNA TGCCACCCGGGTATCTTGTTCAGGTAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGA GTTTTTTTTTTTTTTTTTTTAGTGTAGATATAGACTTTTAAAGGTTAAAAGAAAGAATAA AGATGGAGGGTGTGATAATCCTATGAAGTGTCTTGTTTTGGGTCCTGAGGGCAGCCAATT ACATCCCTTTTTCTTTGTCAATCAACAGTCCAAGTTTGGGTCCCATCACCTGAATCCTGA GGTGTGGATGCTTTAACCTTCAAGATTATGGCCAACGATTATTCCATTTTCCGCCTTCTT TTTCTTCATGAAAACCGATTACCCCCCTTTTTTTTTTCCCACACCTCCTTCTCTATTTTT AACCCCCATTTGACCTTTTTTTTAACCTTTGCATAACGTTTAATGGTTGCTAAATATTCA GCGCATGTCTTTTCACTTTCAAGCTTTTGTTTCATTTTTTTTTTCCCCTTTCCTTACCCG TTTTTTTTTTTTTTGCCCCTTGATAGGTCTTTTGCCACCTACCAACCACGCCCTTTTTAA TTTTTTTGTACTGTGTTGGAGTTTTTAACCACGATGTTCCCTTTTCTTACAGCGCACCTT ACTTTTTTGTTTTCTTTTTTCCACTGTTTTTATTTTTTGTTTTTCCGAGGACCCTTTCCC CGCTTTTTATTTTCACACCCTTTCCGCCCCGAAACCAACGTTTCCACTTTATTTTTTTTT ACCACCACTTTATTTTCGCCTTTCTCAATTATATTTTTTCCCTTTTTATGGAGCACGACC GATTTTTTTACAAGATCGAATGNGCTGAGTTTTACACGCGTTTGNCCCCTTTTGTCTTTT TTTT
Restriction Sites	NotI-NotI
ACCN	NM_080424
Insert Size	2600 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_080424.1, NP_536349.1
RefSeq Size	2591 bp
RefSeq ORF	2142 bp
Locus ID	3431
UniProt ID	Q9HB58
Domains	SAND, BROMO, PHD, Sp100
Protein Families	Druggable Genome, Transcription Factors
Gene Summary	The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (c) represents the longest transcript and it encodes the longest protein (isoform c).

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