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CACNA2D1 (NM_000722) Human Untagged Clone
CAT＃: SC124161
CACNA2D1 (untagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1)
CNY 11,408.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CACNA2; CACNL2A; CCHL2A; LINC01112; lncRNA-N3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000722 edited
ATGGCTGCTGGCTGCCTGCTGGCCTTGACTCTGACACTTTTCCAATCTTTGCTCATCGGC CCCTCGTCGGAGGAGCCGTTCCCTTCGGCCGTCACTATCAAATCATGGGTGGATAAGATG CAAGAAGACCTTGTCACACTGGCAAAAACAGCAAGTGGAGTCAATCAGCTTGTTGATATT TATGAGAAATATCAAGATTTGTATACTGTGGAACCAAATAATGCACGCCAGCTGGTAGAA ATTGCAGCCAGGGATATTGAGAAACTTCTGAGCAACAGATCTAAAGCCCTGGTGCGCCTG GCATTGGAAGCGGAGAAAGTTCAAGCAGCTCACCAGTGGAGAGAAGATTTTGCAAGCAAT GAAGTTGTCTACTACAATGCAAAGGATGATCTCGATCCTGAGAAAAATGACAGTGAGCCA GGCAGCCAGAGGATAAAACCTGTTTTCATTGAAGATGCTAATTTTGGACGACAAATATCT TATCAGCACGCAGCAGTCCATATTCCTACTGACATCTATGAGGGCTCAACAATTGTGTTA AATGAACTCAACTGGACAAGTGCCTTAGATGAAGTTTTCAAAAAGAATCGCGAGGAAGAC CCTTCATTATTGTGGCAGGTTTTTGGCAGTGCCACTGGCCTAGCTCGATATTATCCAGCT TCACCATGGGTTGATAATAGTAGAACTCCAAATAAGATTGACCTTTATGATGTACGCAGA AGACCATGGTACATCCAAGGAGCTGCATCTCCTAAAGACATGCTTATTCTGGTGGATGTG AGTGGAAGTGTTAGTGGATTGACACTTAAACTGATCCGAACATCTGTCTCCGAAATGTTA GAAACCCTCTCAGATGATGATTTCGTGAATGTAGCTTCATTTAACAGCAATGCTCAGGAT GTAAGCTGTTTTCAGCACCTTGTCCAAGCAAATGTAAGAAATAAAAAAGTGTTGAAAGAC GCGGTGAATAATATCACAGCCAAAGGAATTACAGATTATAAGAAGGGCTTTAGTTTTGCT TTTGAACAGCTGCTTAATTATAATGTTTCCAGAGCAAACTGCAATAAGATTATTATGCTA TTCACGGATGGAGGAGAAGAGAGAGCCCAGGAGATATTTAACAAATACAATAAAGATAAA AAAGTACGTGTATTCACGTTTTCAGTTGGTCAACACAATTATGACAGAGGACCTATTCAG TGGATGGCCTGTGAAAACAAAGGTTATTATTATGAAATTCCTTCCATTGGTGCAATAAGA ATCAATACTCAGGAATATTTGGATGTTTTGGGAAGACCAATGGTTTTAGCAGGAGACAAA GCTAAGCAAGTCCAATGGACAAATGTGTACCTGGATGCATTGGAACTGGGACTTGTCATT ACTGGAACTCTTCCGGTCTTCAACATAACCGGCCAATTTGAAAATAAGACAAACTTAAAG AACCAGCTGATTCTTGGTGTGATGGGAGTAGATGTGTCTTTGGAAGATATTAAAAGACTG ACACCACGTTTTACACTGTGCCCCAATGGGTATTACTTTGCAATCGATCCTAATGGTTAT GTTTTATTACATCCAAATCTTCAGCCAAAGAACCCCAAATCTCAGGAGCCAGTAACATTG GATTTCCTTGATGCAGAGTTAGAGAATGATATTAAAGTGGAGATTCGAAATAAGATGATT GATGGGGAAAGTGGAGAAAAAACATTCAGAACTCTGGTTAAATCTCAAGATGAGAGATAT ATTGACAAAGGAAACAGGACATACACATGGACACCTGTCAATGGCACAGATTACAGTTTG GCCTTGGTATTACCAACCTACAGTTTTTACTATATAAAAGCCAAACTAGAAGAGACAATA ACTCAGGCCAGATCAAAAAAGGGCAAAATGAAGGATTCGGAAACCCTGAAGCCAGATAAT TTTGAAGAATCTGGCTATACATTCATAGCACCAAGAGATTACTGCAATGACCTGAAAATA TCGGATAATAACACTGAATTTCTTTTAAATTTCAACGAGTTTATTGATAGAAAAACTCCA AACAACCCATCATGTAACGCGGATTTGATTAATAGAGTCTTGCTTGATGCAGGCTTTACA AATGAACTTGTCCAAAATTACTGGAGTAAGCAGAAAAATATCAAGGGAGTGAAAGCACGA TTTGTTGTGACTGATGGTGGGATTACCAGAGTTTATCCCAAAGAGGCTGGAGAAAATTGG CAAGAAAACCCAGAGACATATGAGGACAGCTTCTATAAAAGGAGCCTAGATAATGATAAC TATGTTTTCACTGCTCCCTACTTTAACAAAAGTGGACCTGGTGCCTATGAATCGGGCATT ATGGTAAGCAAAGCTGTAGAAATATATATTCAAGGGAAACTTCTTAAACCTGCAGTTGTT GGAATTAAAATTGATGTAAATTCCTGGATAGAGAATTTCACCAAAACCTCAATCAGAGAT CCGTGTGCTGGTCCAGTTTGTGACTGCAAAAGAAACAGTGACGTAATGGATTGTGTGATT CTGGATGATGGTGGGTTTCTTCTGATGGCAAATCATGATGATTATACTAATCAGATTGGA AGATTTTTTGGAGAGATTGATCCCAGCTTGATGAGACACCTGGTTAATATATCAGTTTAT GCTTTTAACAAATCTTATGATTATCAGTCAGTATGTGAGCCCGGTGCTGCACCAAAACAA GGAGCAGGACATCGCTCAGCATATGTGCCATCAGTAGCAGACATATTACAAATTGGCTGG TGGGCCACTGCTGCTGCCTGGTCTATTCTACAGCAGTTTCTCTTGAGTTTGACCTTTCCA CGACTCCTTGAGGCAGTTGAGATGGAGGATGATGACTTCACGGCCTCCCTGTCCAAGCAG AGCTGCATTACTGAACAAACCCAGTATTTCTTCGATAACGACAGTAAATCATTCAGTGGT GTATTAGACTGTGGAAACTGTTCCAGAATCTTTCATGGAGAAAAGCTTATGAACACCAAC TTAATATTCATAATGGTTGAGAGCAAAGGGACATGTCCATGTGACACACGACTGCTCATA CAAGCGGAGCAGACTTCTGACGGTCCAAATCCTTGTGACATGGTTAAGCAACCCAGATAC CGAAAAGGGCCTGATGTCTGCTTTGATAACAATGTCTTGGAGGATTATACTGACTGTGGT GGTGTTTCTGGATTAAATCCCTCCCTGTGGTATATCATTGGAATCCAGTTTCTACTACTT TGGCTGGTATCTGGCAGCACACACCGCCTGTTATGA >OriGene 5' read for NM_000722 unedited
TTTTGAATACGACTGACTATAGGGCGGCCGCGAATTCGGCACGAGGCGAGCGCCGGCGGG CTCGCCGAGGTCTGTTTCCAAAGTCGCCCTTGATGGCGGCGGAGGCAAGGCGGCCNNNNN GCGGAGCAGCCGACGCACGCTAGTGGGTCCGCCCGCCACCGCCCCTTCCTCGGCGTCCGC TCCCGCCCTTGCCGTCCCCCGCGCGGCTCCGCGCCTCGGGCCCCGGGCGCAGCCAGCCCT CCAGACGCCCGCGGTCCCGGCGGCGTGTGCTGCTCTTCCTCCGCCCGCGGTTTCCAGCGC CGCTCCTTCCCCCGCTTGGGCAGGGAGGGGGCATTGATCTTCGATCGCGAAGATGGCTGC TGGCTGCCTGCTGGCCTTGACTCTGACACTTTTCCAATCTTTGCTCATCGGCCCCTCGTC GGAGGAGCCGTTCCCTTCGGCCGTCACTATCAAATCATGGGTGGATAAGATGCAAGAAGA CCTTGTCACACTGGCAAAAACAGCAAGTGGAGTCAATCAGCTTGTTGATATTTATGAGAA ATATCAAGATTTGTATACTGTGGAACCAAATAATGCACGCCAGCTGGTAGAAATTGCAGC CAGGGATATTGAGAAACTTCTGAGGCACAGATCTAAAGCCCTGGTGCGCCTGGCATTGGN AAGCGAGAAAGTTCAGCAGCTCACCAGTGGAGAAGAGATTTTTGCAAGCATGAAGTTGTC TACTACAATGCANAAGATGATCTCGATCCCTGAGAAAATGACGTGAGCCAGGCAGCCGA >Forward primer walk for NM_000722 unedited
NAAGAGAGCGGCCGATGGTTAAGCAACCCAAAACCGAAAAGNGCCTGAGTCTGCTTTGAT AACAATGTCTTGGAGGATTATACTGACTGTGGTGGTGTTTCTGGATTAAATCCCTCCCTG TGGTATATCATTGGAATCCAGTTTCTACTACTTTGGCTGGTATCTGGCAGCACACACCGC CTGTTATGACCTTCTAAAAACCAAATCTGCATAGTTAAACTCCAGACCCTGCCAAAACAT GAGCCCTGCCCTCAATTACAGTAACGTAGGGTCAGCTATAAAATCAGACAAACATTAGCT GGGCCTGTTCCATGGCATAACACTAAGGCGCAGACTCCTAAGGCACCCACTGGCTGCATG TCAGGGTGTCAGATCCTTAAACGTGTGTGAATGCTGCATCATCTATGTGTAACATCAAAG CAAAATCCTATACGTGTCCTCTATTGGAAAATTTGGGAGTTTGTTGTTGCATTGTTGGTG ATTACATGTGAAAGGGTTCCCCATACAATTGTTAATGAACCATAAGAAATGTCTTGATAT TGACCTGGAATTTTGACTTGCTGCAATTTTACTAAGAAAATCTCTAAGGGGAAAGAAATT ATTTTTGCCTTCACTTTTTCTTCTGTGANAAGTTAATTCCTGCTTTAAGTAGCAATTATT GAAATATATAGAGAAAGAAGAGATTAACATTGGTCTAAATTGTTGAAATATANATAATGG CTAATTTTCTATGAAAAATTTGCCATGAATAANATGCCTTATGAANAACGGCTTCTTTGC CAAAAATAAACACATTTGATGACCAATTCATTTTGATGNGTAATGAATTGATGGTTTTGA AATAGTAACTAANAAATTATTAAACTAAAGGTGCTTGAGGAAGAAATTTAATATGT |
| Restriction Sites | Please inquire |
| ACCN | NM_000722 |
| Insert Size | 6400 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_000722.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000722.2, NP_000713.2 |
| RefSeq Size | 3822 bp |
| RefSeq ORF | 3276 bp |
| Locus ID | 781 |
| UniProt ID | P54289 |
| Domains | VWA, Cache |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219081 | CACNA2D1 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1) |
CNY 11,392.00 |
|
| RC219081L1 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1), Myc-DDK-tagged |
CNY 13,792.00 |
|
| RC219081L2 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1), mGFP tagged |
CNY 7,600.00 |
|
| RC219081L3 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1), Myc-DDK-tagged |
CNY 7,600.00 |
|
| RC219081L4 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1), mGFP tagged |
CNY 13,792.00 |
|
| RG219081 | CACNA2D1 (tGFP-tagged) - Human calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1) |
CNY 12,992.00 |
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