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DMGDH (NM_013391) Human Untagged Clone
CAT＃: SC124128
DMGDH (untagged)-Human dimethylglycine dehydrogenase (DMGDH), nuclear gene encoding mitochondrial protein
CNY 16,720.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DMGDHD; ME2GLYDH |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_013391, the custom clone sequence may differ by one or more nucleotides
ATGCTCCGTCCCGGCGCGCAGCTGCTGCGGGGCCTCCTGCTGCGGAGCTGCCCGCTGCAGGGCTCCCCCG GGCGCCCGCGCTCTGTCTGCGGCCGGGAAGGAGAGGAAAAACCACCCTTATCTGCAGAAACACAATGGAA AGACAGAGCAGAAACAGTGATAATTGGAGGTGGCTGTGTTGGTGTGAGTCTGGCTTATCACCTGGCCAAA GCAGGGATGAAAGATGTGGTCCTGCTGGAGAAATCAGAGCTCACGGCTGGATCTACCTGGCACGCAGCAG GTTTAACAACTTACTTTCATCCTGGAATAAACTTGAAGAAAATACATTATGATAGCATCAAACTTTATGA GAAACTGGAAGAAGAAACTGGTCAGGTGGTGGGATTCCATCAGCCAGGTAGTATCAGACTTGCTACCACC CCTGTAAGGGTAGATGAATTTAAATATCAAATGACTCGGACTGGCTGGCATGCAACAGAACAGTATCTCA TTGAACCTGAAAAAATTCAAGAGATGTTCCCTTTACTCAACATGAATAAGGTTTTAGCTGGATTGTATAA TCCTGGAGATGGTCACATTGATCCTTATTCTCTAACTATGGCACTGGCTGCTGGGGCTAGGAAATGTGGT GCCCTTTTAAAATATCCTGCACCAGTAACTTCTCTGAAAGCCAGGTCAGATGGAACATGGGACGTTGAAA CACCACAGGGGTCTATGAGAGCAAATAGAATTGTGAATGCTGCAGGATTTTGGGCTCGTGAAGTAGGTAA AATGATTGGACTAGAACATCCTCTCATTCCGGTTCAACATCAATATGTTGTTACATCGACTATATCTGAA GTGAAAGCTTTGAAACGAGAACTGCCTGTGCTCCGTGACCTGGAAGGATCATATTATCTCCGACAGGAAA GGGATGGGCTTTTGTTTGGTCCATATGAAAGTCAAGAGAAAATGAAAGTTCAGGACTCCTGGGTCACCAA TGGAGTTCCTCCAGGTTTTGGAAAGGAACTCTTTGAGTCTGATCTAGATCGAATCATGGAACACATCAAA GCTGCCATGGAAATGGTTCCTGTCTTGAAAAAGGCTGACATCATCAATGTTGTCAATGGTCCTATCACGT ATTCTCCTGACATTCTGCCTATGGTGGGGCCCCATCAGGGGGTCAGAAACTACTGGGTGGCTATAGGCTT TGGATATGGCATAATCCACGCTGGTGGGGTAGGGAAATATCTCAGTGACTGGATCCTGCATGGAGAACCT CCTTTTGATCTGATAGAATTGGATCCTAATCGCTATGGCAAATGGACAACAACCCAGTACACTGAGGCCA AAGCAAGAGAATCATATGGATTCAACAATATTGTTGGTTATCCTAAAGAAGAACGGTTTGCTGGGAGGCC GACTCAACGAGTCAGTGGGCTCTATCAAAGGCTGGAGTCTAAGTGTTCCATGGGGTTCCATGCTGGCTGG GAGCAGCCGCACTGGTTCTACAAACCAGGCCAGGACACTCAGTACAGGCCAAGTTTTCGCCGCACAAACT GGTTTGAGCCTGTGGGCTCGGAGTATAAACAGGTTATGCAAAGAGTAGCGGTAACTGACCTATCACCATT TGGCAAGTTTAACATCAAAGGCCAAGATTCCATTAGACTACTGGACCATCTCTTTGCAAATGTCATTCCA AAGGTGGGTTTTACAAATATAAGTCACATGTTAACACCCAAGGGTCGAGTGTATGCTGAGCTGACTGTTT CTCACCAATCTCCTGGGGAGTTTCTTTTAATTACTGGCTCTGGATCAGAACTTCATGATCTTAGATGGAT TGAAGAAGAAGCAGTCAAAGGTGGATATGATGTTGAAATTAAAAACATAACTGATGAGCTTGGAGTTCTT GGAGTTGCTGGGCCACAGGCAAGAAAGGTCCTTCAGAAACTGACCTCTGAAGATCTTAGTGATGATGTTT TCAAGTTTCTTCAAACCAAGTCCTTAAAGGTTTCCAACATTCCTGTCACTGCTATTAGGATATCTTATAC TGGTGAGCTGGGTTGGGAGCTGTATCACAGAAGAGAAGATTCTGTGGCGCTGTATGACGCTATCATGAAT GCAGGCCAGGAGGAGGGAATCGACAATTTTGGAACCTATGCCATGAATGCCTTACGCCTGGAGAAAGCCT TCAGAGCCTGGGGGTTAGAGATGAACTGTGATACAAATCCTTTGGAAGCTGGACTGGAATATTTTGTGAA GTTAAATAAGCCAGCAGACTTCATAGGAAAGCAAGCACTGAAACAGATTAAAGCCAAGGGGCTGAAACGA AGACTGGTCTGCCTCACCTTGGCAACGGATGATGTTGATCCAGAGGGAAATGAAAGCATCTGGTACAATG GCAAGGTGGTTGGCAACACGACATCTGGAAGCTATAGCTACAGCATCCAGAAGAGTCTGGCTTTCGCATA TGTCCCTGTACAACTAAGTGAAGTGGGACAGCAAGTGGAAGTTGAACTATTAGGCAAAAATTACCCAGCA GTCATCATACAAGAACCTTTGGTATTGACCGAACCAACCAGAAACCGGCTTCAGAAAAAAGGTGGAAAGG ACAAAACTTGA >OriGene 5' read for NM_013391 unedited
AGGGGATGGATTGNNCNNAATGAGTCAGCCTTTTGTAATACGCGAGAGTATAGGGCGGCC GCGAATTNGGCCGAGGCCTAGTCATGCTCCGTCCCGGCGCGCAGCTGCTGCGGGGCCTCC TGCTGCGGAGCTGCCCGCTGCAGGGCTCCCCCGGGCGCCCGCGCTCTGTCTGCGGCCGGG AAGGAGAGGAAAAACCACCCTTATCTGCAGAAACACAATGGAAAGACAGAGCAGAAACAG TGATAATTGGAGGTGGCTGTGTTGGTGTGAGTCTGGCTTATCACCTGGCCAAAGCAGGGA TGAAAGATGTGGTCCTGCTGGAGAAATCAGAGCTCACGGCTGGATCTACCTGGCACGCAG CAGGTTTAACAACTTACTTTCATCCTGGAATAAACTTGAAGAAAATACATTATGATAGCA TCAAACTTTATGAGAAACTGGAAGAAGAAACTGGTCAGGTGGTGGGATTCCATCAGCCAG GTAGTATCAGACTTGCTACCACCCCTGTGAGGGTTGATGAATTTAAATATCAAATGACTC GGACTGGCTGGCATGCAACAGAACAGTATCTCATTGAACCTGAAAAAATTCAAGAGATGT TCCCCTTACTCCACATGGATAAGGGTTTAACTTGGATGGATAATCCCTGGGATGGGCACA ATGATTCCCTATCTCTAACTATTGCACTTGGTGGTGGGGCTATGAAATATGGTGCGCCTT TTAAATATTCTGGCCACGTACTTCTTTGAAGCCAGTCAGATGGACATGGGACCTGAAACC CCCGGGTCTTTGAGCAAATAATTGGAGCGGC >OriGene 3' read for NM_013391 unedited
TCCGGAGCGCGGAGAGGCACTGGGGAGGGGTCAAGGGATGCCACCCGGGATCTGTTCAGG AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTACATGTTTTTATGTAAAAAATAATTTATTAATTTGTTTTC AGCTGTCAAGAACCGAATGCTTTTGTTACTAAAATTATAAAATGTCCCTTAATTAGGTTA TAGTAATGATTGGGTATTTTAGCAAACACCTAAATGTTTTACTGATTGGGTAATGGGGGG TAAATAAAAAAACATTCATTTCAAATTTTTTCATTTAAAAAAACAATGGAAATCATTTAT CTATTATTCTGGCTTGCTTAAAAAACACTTAACAGAAAGGTTTCATTAAAATTCTAAATT TAAACTTTGATGATTTTGAAATGAATTCCTGGTTTCCTCTATTCCCCTGGGAGCCAGTTA TAATAATTTCAAGGACAGTCATTAGCAACTTTAATTCAGTTGACTGCTGAAGGTCTTTTT TCAAGTTTGGTCCTTTCCCCCTTTTTTTTGAACCCGGTTTCTGGTTGGTTCGGTCAATCC CAAAGGTTCTTGTTTGATGACTGCTGGGTAATTTTGCCTATAGTTAACTTCATTGGTGTC CACTTATTTATTGCCAGGCCATTTCAAAGCAACTCTTTGGATCTGACTATGCTCAAATTC GGTGCACACCTGCCTTGACAAGCTTAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_013391 |
| Insert Size | 3700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_013391.2, NP_037523.2 |
| RefSeq Size | 3104 bp |
| RefSeq ORF | 2601 bp |
| Locus ID | 29958 |
| UniProt ID | Q9UI17 |
| Domains | DAO, GCV_T |
| Protein Pathways | Glycine, serine and threonine metabolism, Metabolic pathways |
| Gene Summary | This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (1) represents the longest transcript and encodes the supported protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223089 | DMGDH (Myc-DDK-tagged)-Human dimethylglycine dehydrogenase (DMGDH), nuclear gene encoding mitochondrial protein |
CNY 6,344.00 |
|
| RC223089L3 | Lenti-ORF clone of DMGDH (Myc-DDK-tagged)-Human dimethylglycine dehydrogenase (DMGDH), nuclear gene encoding mitochondrial protein |
CNY 9,030.00 |
|
| RC223089L4 | Lenti-ORF clone of DMGDH (mGFP-tagged)-Human dimethylglycine dehydrogenase (DMGDH), nuclear gene encoding mitochondrial protein |
CNY 9,030.00 |
|
| RG223089 | DMGDH (tGFP-tagged) - Human dimethylglycine dehydrogenase (DMGDH), nuclear gene encoding mitochondrial protein |
CNY 7,890.00 |
