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ACE2 (NM_021804) Human Untagged Clone (Angiotensin Converting Enzyme 2)
CAT＃: SC124099
ACE2 (untagged)-Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2)
CNY 8,856.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACEH |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_021804, the custom clone sequence may differ by one or more nucleotides
ATGTCAAGCTCTTCCTGGCTCCTTCTCAGCCTTGTTGCTGTAACTGCTGCTCAGTCCACCATTGAGGAAC AGGCCAAGACATTTTTGGACAAGTTTAACCACGAAGCCGAAGACCTGTTCTATCAAAGTTCACTTGCTTC TTGGAATTATAACACCAATATTACTGAAGAGAATGTCCAAAACATGAATAATGCTGGGGACAAATGGTCT GCCTTTTTAAAGGAACAGTCCACACTTGCCCAAATGTATCCACTACAAGAAATTCAGAATCTCACAGTCA AGCTTCAGCTGCAGGCTCTTCAGCAAAATGGGTCTTCAGTGCTCTCAGAAGACAAGAGCAAACGGTTGAA CACAATTCTAAATACAATGAGCACCATCTACAGTACTGGAAAAGTTTGTAACCCAGATAATCCACAAGAA TGCTTATTACTTGAACCAGGTTTGAATGAAATAATGGCAAACAGTTTAGACTACAATGAGAGGCTCTGGG CTTGGGAAAGCTGGAGATCTGAGGTCGGCAAGCAGCTGAGGCCATTATATGAAGAGTATGTGGTCTTGAA AAATGAGATGGCAAGAGCAAATCATTATGAGGACTATGGGGATTATTGGAGAGGAGACTATGAAGTAAAT GGGGTAGATGGCTATGACTACAGCCGCGGCCAGTTGATTGAAGATGTGGAACATACCTTTGAAGAGATTA AACCATTATATGAACATCTTCATGCCTATGTGAGGGCAAAGTTGATGAATGCCTATCCTTCCTATATCAG TCCAATTGGATGCCTCCCTGCTCATTTGCTTGGTGATATGTGGGGTAGATTTTGGACAAATCTGTACTCT TTGACAGTTCCCTTTGGACAGAAACCAAACATAGATGTTACTGATGCAATGGTGGACCAGGCCTGGGATG CACAGAGAATATTCAAGGAGGCCGAGAAGTTCTTTGTATCTGTTGGTCTTCCTAATATGACTCAAGGATT CTGGGAAAATTCCATGCTAACGGACCCAGGAAATGTTCAGAAAGCAGTCTGCCATCCCACAGCTTGGGAC CTGGGGAAGGGCGACTTCAGGATCCTTATGTGCACAAAGGTGACAATGGACGACTTCCTGACAGCTCATC ATGAGATGGGGCATATCCAGTATGATATGGCATATGCTGCACAACCTTTTCTGCTAAGAAATGGAGCTAA TGAAGGATTCCATGAAGCTGTTGGGGAAATCATGTCACTTTCTGCAGCCACACCTAAGCATTTAAAATCC ATTGGTCTTCTGTCACCCGATTTTCAAGAAGACAATGAAACAGAAATAAACTTCCTGCTCAAACAAGCAC TCACGATTGTTGGGACTCTGCCATTTACTTACATGTTAGAGAAGTGGAGGTGGATGGTCTTTAAAGGGGA AATTCCCAAAGACCAGTGGATGAAAAAGTGGTGGGAGATGAAGCGAGAGATAGTTGGGGTGGTGGAACCT GTGCCCCATGATGAAACATACTGTGACCCCGCATCTCTGTTCCATGTTTCTAATGATTACTCATTCATTC GATATTACACAAGGACCCTTTACCAATTCCAGTTTCAAGAAGCACTTTGTCAAGCAGCTAAACATGAAGG CCCTCTGCACAAATGTGACATCTCAAACTCTACAGAAGCTGGACAGAAACTGTTCAATATGCTGAGGCTT GGAAAATCAGAACCCTGGACCCTAGCATTGGAAAATGTTGTAGGAGCAAAGAACATGAATGTAAGGCCAC TGCTCAACTACTTTGAGCCCTTATTTACCTGGCTGAAAGACCAGAACAAGAATTCTTTTGTGGGATGGAG TACCGACTGGAGTCCATATGCAGACCAAAGCATCAAAGTGAGGATAAGCCTAAAATCAGCTCTTGGAGAT AAAGCATATGAATGGAACGACAATGAAATGTACCTGTTCCGATCATCTGTTGCATATGCTATGAGGCAGT ACTTTTTAAAAGTAAAAAATCAGATGATTCTTTTTGGGGAGGAGGATGTGCGAGTGGCTAATTTGAAACC AAGAATCTCCTTTAATTTCTTTGTCACTGCACCTAAAAATGTGTCTGATATCATTCCTAGAACTGAAGTT GAAAAGGCCATCAGGATGTCCCGGAGCCGTATCAATGATGCTTTCCGTCTGAATGACAACAGCCTAGAGT TTCTGGGGATACAGCCAACACTTGGACCTCCTAACCAGCCCCCTGTTTCCATATGGCTGATTGTTTTTGG AGTTGTGATGGGAGTGATAGTGGTTGGCATTGTCATCCTGATCTTCACTGGGATCAGAGATCGGAAGAAG AAAAATAAAGCAAGAAGTGGAGAAAATCCTTATGCCTCCATCGATATTAGCAAAGGAGAAAATAATCCAG GATTCCAAAACACTGATGATGTTCAGACCTCCTTTTAG >OriGene 5' read for NM_021804 unedited
AAAGTCAGTATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGAAAGGAA GAGGAAGTAACTTGTGGAATGTTGAGAAAGCGCCCAACCCAAGTTCAAAGGCTGATAAGA GAGAAAATCTCATGAGGAGGTTTTAGTCTAGGGAAAGTCATTCAGTGGATGTGATCTTGG CTCACAGGGGACGATGTCAAGCTCTTCCTGGCTCCTTCTCAGCCTTGTTGCTGTAACTGC TGCTCAGTCCACCATTGAGGAACAGGCCAAGACATTTTTGGACAAGTTTAACCACGAAGC CGAAGACCTGTTCTATCAAAGTTCACTTGCTTCTTGGAATTATAACACCAATATTACTGA AGAGAATGTCCAAAACATGAATAATGCTGGGGACAAATGGTCTGCCTTTTTAAAGGAACA GTCCACACTTGCCCAAATGTATCCACTACAAGAAATTCAGAATCTCACAGTCAAGCTTCA GCTGCAGGCTCTTCAGCAAAATGGGTCTTCAGTGCTCTCAGAAGACAAGAGCAAACGGTT GAACACAATTCTAAATACAATGAGCACCATCTACCGTACTGGAAAAGTTTGGTACCCCGA TAATCCACAAGAATGCTTATTACTTGAACCAGGTTTGAATGAAATAATGGCCAACATTTT ATACTACAATGAGAGGCTCTGGGCTTGGGAAAACTGGAGATCTGATGTCGGCAAGCACTG GAGCCCTTTTATAAAAAGATGTGGTCTTGAAAAAGAGAGGGCCGAGCCAAACTTTTTAGG GCCATGGGGATATTTGGGAGGGGCCATTCAAACAATGGGGGAATGGCTTATACTCGCCCC GCCCCTTTTTGAAAATGTGACCTCCCTTTGAGGAATAAACCCTTTTTTAA >OriGene 3' read for NM_021804 unedited
GGAGTGGCACTGGGGAGGCGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTA TGATTTTTGCCGCAATCTAGAGTNNNNGTGTTTTTTGGGTTTTTTGTGTGTAAATCTAGC ATTTATTGAGTGTCTGCTTCGTGCTCAACACTGCTCATACACTGTGAGCAAATACAAAAT ATTTAAGAGACTGGGTACCCACTTCATAGGGTGAACATACAGTTGGAATTTCCATTCACT CCATAGTTAGAGAACAGTAGAAATGAGTTTCTATCAAGCATGCTCTGGGAGTTCACGGAG GCCCCTGGCTCTAGTTTTGTGTTGTCAGGGAGATGTTGATCAAGCACCTTGGAAGTGAAA AAGCAATGTCCTCTACCTGTTCCCTGGATTCTTCTCTCTTTAGACCTGTCACCTTGAAGA AAGCATGATCGATTCCAAACATCACTGTAGGCAAATCACCATAGTACTTGAACTGAGTTA CTGTGAAGAAAGCATGTCATCCTTGACTATGGATTAAATGAAAGTGAGCTAATGCTTGCC CTTCTAAATCCTTGCAGCTACAACCATTTCCCAGGCCCTTGTCCTTACAACGTGATTCCA TCCCTTATTCCATACAGAGATCCAACACCTTGCTCCAATGATATATTCCTTGTTTTACAC TTCAGAAATTTCACACACATTTAGCGTTTAGATTATCCTTGAACCAGCTTGTGAAGACCC AATACACCACTTCGCTTAATATACTCTTATACAAAAATTCTTATTAAGAATCAGAAG |
| Restriction Sites | Please inquire |
| ACCN | NM_021804 |
| Insert Size | 3800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021804.1, NP_068576.1 |
| RefSeq Size | 3405 bp |
| RefSeq ORF | 2418 bp |
| Locus ID | 59272 |
| UniProt ID | Q9BYF1 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Renin-angiotensin system |
| Gene Summary | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible. [provided by RefSeq, Nov 2020] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208442 | ACE2 (Myc-DDK-tagged)-Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) |
CNY 5,896.00 |
|
| RC208442L1 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), Myc-DDK-tagged |
CNY 8,296.00 |
|
| RC208442L2 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), mGFP tagged |
CNY 8,296.00 |
|
| RC208442L3 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), Myc-DDK-tagged |
CNY 8,296.00 |
|
| RC208442L4 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), mGFP tagged |
CNY 8,296.00 |
|
| RG208442 | ACE2 (tGFP-tagged) - Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) |
CNY 7,496.00 |
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