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CACNB2 (NM_000724) Human Untagged Clone
CAT＃: SC124059
CACNB2 (untagged)-Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1
CNY 4,512.00
CNY 9,790.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAB2; CACNLB2; CAVB2; MYSB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124059 sequence for NM_000724 edited (data generated by NextGen Sequencing)
ATGCAGTGCTGCGGGCTGGTGCATCGCCGGCGAGTACGGGTGTCCTATGGTTCGGCAGAC TCCTACACTAGCCGTCCATCCGATTCCGATGTATCTCTGGAGGAGGACCGGGAGGCAGTG CGCAGAGAAGCGGAGCGGCAGGCCCAGGCACAGTTGGAAAAAGCAAAGACAAAGCCCGTT GCATTTGCGGTTCGGACAAATGTCAGCTACAGTGCGGCCCATGAAGATGATGTTCCAGTG CCTGGCATGGCCATCTCATTCGAAGCAAAAGATTTTCTGCATGTTAAGGAAAAATTTAAC AATGACTGGTGGATAGGGCGATTGGTAAAAGAAGGCTGTGAAATCGGATTCATTCCAAGC CCAGTCAAACTAGAAAACATGAGGCTGCAGCATGAACAGAGAGCCAAGCAAGGGAAATTC TACTCCAGTAAATCAGGAGGAAATTCATCATCCAGTTTGGGTGACATAGTACCTAGTTCC AGAAAATCAACACCTCCATCATCTGCTATAGACATAGATGCTACTGGCTTAGATGCAGAA GAAAATGATATTCCAGCAAACCACCGCTCCCCTAAACCCAGTGCAAACAGTGTAACGTCA CCCCACTCCAAAGAGAAAAGAATGCCCTTCTTTAAGAAGACAGAGCACACTCCTCCGTAT GATGTGGTACCTTCCATGCGACCAGTGGTCCTAGTGGGCCCTTCTCTGAAGGGCTACGAG GTCACAGATATGATGCAAAAAGCGCTGTTTGATTTTTTAAAACACAGATTTGAAGGGCGG ATATCCATCACAAGGGTCACCGCTGACATCTCGCTTGCCAAACGCTCGGTATTAAACAAT CCCAGTAAGCACGCAATAATAGAAAGATCCAACACAAGGTCAAGCTTAGCGGAAGTTCAG AGTGAAATCGAAAGGATTTTTGAACTTGCAAGAACATTGCAGTTGGTGGTCCTTGACGCG GATACAATTAATCATCCAGCTCAACTCAGTAAAACCTCCTTGGCCCCTATTATAGTATAT GTAAAGATTTCTTCTCCTAAGGTTTTACAAAGGTTAATAAAATCTCGAGGGAAATCTCAA GCTAAACACCTCAACGTCCAGATGGTAGCAGCTGATAAACTGGCTCAGTGTCCTCCAGAG CTGTTCGATGTGATCTTGGATGAGAACCAGCTTGAGGATGCCTGTGAGCACCTTGCCGAC TATCTGGAGGCCTACTGGAAGGCCACCCATCCTCCCAGCAGTAGCCTCCCCAACCCTCTC CTTAGCCGTACATTAGCCACTTCAAGTCTGCCTCTTAGCCCCACCCTAGCCTCTAATTCA CAGGGTTCTCAAGGTGATCAGAGGACTGATCGCTCCGCTCCTATCCGTTCTGCTTCCCAA GCTGAAGAAGAACCTAGTGTGGAACCAGTCAAGAAATCCCAGCACCGCTCTTCCTCCTCA GCCCCACACCACAACCATCGCAGTGGGACAAGTCGCGGCCTCTCCAGGCAAGAGACATTT GACTCGGAAACCCAGGAGAGTCGAGACTCTGCCTACGTAGAGCCAAAGGAAGATTATTCC CATGACCACGTGGACCACTATGCCTCACACCGTGACCACAACCACAGAGACGAGACCCAC GGGAGCAGTGACCACAGACACAGGGAGTCCCGGCACCGTTCCCGGGACGTGGATCGAGAG CAGGACCACAACGAGTGCAACAAGCAGCGCAGCCGTCATAAATCCAAGGATCGCTACTGT GAAAAGGATGGAGAAGTGATATCAAAAAAACGGAATGAGGCTGGGGAGTGGAACAGGGAT GTTTACATCCGCCAATGA Clone variation with respect to NM_000724.3 >OriGene 5' read for NM_000724 unedited
GGCGCGATACATTCTGACACCGGACAAATCAAATTGCCCAAAAGTTACAGAGGTAACAGT GAATCCAGGATGCTGCTATCAGCCTGTGCATTGTGAAGAAGGCAATCATAGGCGAGCAGC CGCGGGAGCAGGAACAGCAGCGTGCTAAGAAGCAGTCACATAAACAGCAGCAGGAGTATG TTTTCTGCTTTTCAAAAGCAGAGTACTGCAGGGTCGCGAAATGCAAGACACTCAGATGTT TGAAAATCTCCCGAGTTGAGAATGGCTACTGTAAAAGCGTCACCAAGAAACTCTGACGAT CTGGACAGTCCTAACTCTGTGTTAGCAATACTTACTTCCGGAAAATTAATGCTACTTCTT GTAGATTTTTGCAAATAGGAAACCCCCTTGAAGAAGATCTCAAATTACGCCCCCCACCCC CAAAAAAAGACAAACAGGGGAGAACAAAGTTTTGGCATGCCTGCAGGAACGGTGGCTTTT TTAGAAACTACCTAGGAGGCAGAAGCTAAGTGATTTGCTCATGCCTCTTACCTGGGAGTA GAAGGTGGGAAGAAATGGACCGAGGCTGTGACGAGAAGACAAGGCACAGTGCAGCTTGGT GAAGCCACACGCTGACTGCGTTCTGCCCCCTCTTCATGCAGTGCTGCGGGCTGGTGCATC GCCGGCGAGTACGGGTGTCCTATGGTTCGGCAGACTCCTACACTAGCCGTCCATCCGATT CCGATGTATTTCTGGAGGAGGACCGGGAGGCAGTGCGCATAGAACCGGAGCGGCAGGCCC AGGCCAGTTGGTAAAAGCAAAGACCAACCCGTTGGCATTGCGGTTCGGACAAATGTCAGC TACCGTGCGGCCT >OriGene 3' read for NM_000724 unedited
CCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAG CTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGTGGGAGAA GTTATAAAAATTTATTTTCCCACGAAATAATTCCACAAGCTGTGTAAACAAACATTTCTT ACTAAAACAAATACTCTAACACACAAAGATTGTACATTTCCAGTGAAACACTCACAGTAA AATTGCCTGTATTTTCACTCTCTAGGAGCAAAAACAAGGAGGCAGCAGATGAATGCTTTC CTAGTTACCTTTGGCAGCAAGCTTACTCACATTCCCTGACTGCTCAATGGGTTGTTAAAG CAACATATAGCACAATTAATTAAATACCGGACCGAGGTGGGCAGAATGCTCGATATCAGT CTCTAGTTTCTTCGTTAGTCTTCAGCATTCCAATTCATCTCAACCATTCAGTCACTCGGT GCACACTTTCTTACATACGGACACACACACGTGCATATAGCGAGTTCCGGCTCGTAGACT CCAGTGCAGTGACTAGAACAGACACTAGCTACTAAGAATGTGTCACAATCAGTGTGAACT GTATGGAGTAGAACAACCTCTGGAGTTNTATATTTACCATAATTTATGGTGGAAATTACA AACTTACTTANCAGGATGGTATAACATTCAGAATTCAAACCTTTTTCAGTCAAGCAATCA CCCATATTACAGTATGTACACACTTTCTACTAGATTGAGGAAGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000724 |
| Insert Size | 4200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000724.2, NP_000715.1 |
| RefSeq Size | 3721 bp |
| RefSeq ORF | 1818 bp |
| Locus ID | 783 |
| UniProt ID | Q08289 |
| Domains | Ca_channel_B, SH3, GuKc |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013] Transcript Variant: This variant (1) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 2. These differences cause translation initiation at an alternate start codon, and result in an isoform (1) with a shorter and distinct N-terminus, compared to isoform 2. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216641 | CACNB2 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1 |
CNY 4,504.00 |
|
| RC216641L1 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, Myc-DDK-tagged |
CNY 6,904.00 |
|
| RC216641L2 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC216641L3 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, Myc-DDK-tagged |
CNY 6,904.00 |
|
| RC216641L4 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1, mGFP tagged |
CNY 6,904.00 |
|
| RG216641 | CACNB2 (tGFP-tagged) - Human calcium channel, voltage-dependent, beta 2 subunit (CACNB2), transcript variant 1 |
CNY 6,104.00 |
