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PDE1C (NM_005020) Human Untagged Clone
CAT＃: SC124021
PDE1C (untagged)-Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4
CNY 4,728.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | cam-PDE 1C; DFNA74; hCam-3; Hcam3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC124021 sequence for NM_005020 edited (data generated by NextGen Sequencing)
ATGGAGTCGCCAACCAAGGAGATTGAAGAATTTGAGAGCAACTCTCTGAAATACCTGTAA CCGGAACAGATCGAGAAAATCTGGCTTCGGCTCCGCGGGCTGAGGAAATATAAGAAAACG TCCCAGAGATTACGGTCTTTGGTCAAACAATTAGAGAGAGGGGAAGCTTCAGTGGTAGAT CTTAAGAAGAATTTGGAATATGCAGCCACAGTGCTTGAATCTGTGTATATTGATGAAACA AGGAGACTCCTGGATACAGAGGATGAGCTCAGTGACATTCAGTCAGATGCTGTGCCTTCT GAGGTCCGAGACTGGCTGGCCTCCACCTTCACGCGGCAGATGGGGATGATGCTCAGGAGG AGCGACGAGAAGCCCCGGTTCAAGAGCATCGTTCACGCAGTGCAGGCTGGGATATTTGTG GAGAGAATGTATAGACGGACATCAAACATGGTTGGACTGAGCTATCCACCAGCTGTTATT GAGGCATTAAAGGATGTGGACAAGTGGTCCTTTGACGTCTTTTCCCTCAATGAGGCCAGT GGGGATCATGCACTGAAATTTATTTTCTATGAACTACTCACACGTTATGATCTGATCAGC CGTTTCAAGATCCCCATTTCTGCACTTGTCTCATTTGTGGAGGCCCTGGAAGTGGGATAC AGCAAGCACAAAAATCCTTACCATAACTTAATGCACGCTGCCGATGTTACACAGACAGTG CATTACCTCCTCTATAAGACAGGAGTGGCGAACTGGCTGACGGAGCTGGAGATCTTTGCT ATAATCTTCTCAGCTGCCATCCATGACTACGAGCATACCGGAACCACCAACAATTTCCAC ATTCAGACTCGGTCTGATCCAGCTATTCTGTATAATGACAGATCTGTACTGGAGAATCAC CATTTAAGTGCAGCTTATCGCCTTCTGCAAGATGACGAGGAAATGAATATTTTGATTAAC CTCTCAAAGGATGACTGGAGGGAGTTTCGAACCTTGGTAATTGAAATGGTGATGGCCACA GATATGTCTTGTCACTTCCAACAAATCAAAGCAATGAAGACTGCTCTGCAGCAGCCAGAA GCCATTGAAAAGCCAAAAGCCTTATCCCTTATGCTGCATACAGCAGATATTAGCCATCCA GCAAAAGCATGGGACCTCCATCATCGCTGGACAATGTCACTCCTGGAGGAGTTCTTCAGA CAGGGTGACAGAGAAGCAGAGCTGGGGCTGCCTTTTTCTCCTCTGTGTGACCGAAAGTCC ACTATGGTTGCTCAGTCACAAGTAGGTTTCATTGATTTCATCGTGGAACCCACCTTCACT GTGCTTACGGACATGACCGAGAAGATTGTGAGTCCATTAATCGATGAAACCTCTCAAACT GGTGGGACAGGACAGAGGCGTTCGAGTTTGAATAGCATCAGCTCGTCAGATGCCAAGCGA TCAGGTGTCAAGACCTCTGGTTCAGAGGGAAGTGCCCCGATCAACAATTCTGTCATCTCC GTTGACTATAAGAGCTTTAAAGCTACTTGGACGGAAGTGGTGCACATCAATCGGGAGAGA TGGAGGGCCAAGGTACCCAAAGAGGAGAAGGCCAAGAAGGAAGCAGAGGAAAAGGCTCGC CTGGCCGCAGAGGAGCAGCAAAAGGAAATGGAAGCCAAAAGCCAGGCTGAAGAAGGCGCA TCTGGCAAAGCTGAGAAAAAGACGTCTGGAGAAACTAAGAATCAAGTCAATGGAACACGG GCAAACAAAAGTGACAACCCTCGTGGGAAAAATTCCAAAGCTGAGAAGTCATCAGGAGAA CAGCAACAGAATGGTGACTTCAAAGATGGCAAAAATAAGACAGACAAGAAGGATCACTCT AACATCGGAAATGATTCAAAGAAAACAGATGATTCACAAGAGTAA Clone variation with respect to NM_005020.2 58 c=>t;1773 c=>t;1782 c=>t;1830 t=>c >OriGene 5' read for NM_005020 unedited
TTTGAATACGACTGACTATAGGGCGGCCGCGAATTCGGCACGAGGGACAGCCCAAACTAT CTCAGCTTCACCGCCAGTGGTCACCTACCTGCAGCTATGGAGTCGCCAACCAAGGAGATT GAAGAATTTGAGAGCAACTCTCTGAAATACCTGTAACCGGAACAGATCGAGAAAATCTGG CTTCGGCTCCGCGGGCTGAGGAAATATAAGAAAACGTCCCAGAGATTACGGTCTTTGGTC AAACAATTAGAGAGAGGGGAAGCTTCAGTGGTAGATCTTAAGAAGAATTTGGAATATGCA GCCACAGTGCTTGAATCTGTGTATATTGATGAAACAAGGAGACTCCTGGATACAGAGGAT GAGCTCAGTGACATTCAGTCAGATGCTGTGCCTTCTGAGGTCCGAGACTGGCTGGCCTCC ACCTTCACGCGGCAGATGGGGATGATGCTCAGGAGGAGCGACGAGAAGCCCCGGTTCAAG AGCATCGTTCACGCAGTGCAGGCTGGGATATTTGTGGAGAGAATGTATAGACGGACATCA AACATGGTTGGACTGAGCTATCCACCAGCTGTTATTGAGGCATTAAAGGATGTGGACAAG TGGTCCTTTGACGTCTTTTCCCTCAATGAGGCCAGTGGGGATCATGCACTGAAATTTATT TTCTATGAACTACTCACACGTTATGATCTGATCAGCCGTTTCAAGATCCCCATTTCTGCA CTTGTCTCATTTGTGGAGGCCCTGGAAGT |
| Restriction Sites | Please inquire |
| ACCN | NM_005020 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005020.1, NP_005011.1 |
| RefSeq Size | 2694 bp |
| RefSeq ORF | 1905 bp |
| Locus ID | 5137 |
| UniProt ID | Q14123 |
| Domains | PDEase, HDc |
| Protein Families | Druggable Genome |
| Protein Pathways | Calcium signaling pathway, Olfactory transduction, Progesterone-mediated oocyte maturation, Purine metabolism |
| Gene Summary | This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016] Transcript Variant: This variant (4) differs in the 5' and 3' UTR and has multiple coding region differences, compared to variant 3. These differences result in an isoform (1) with distinct N- and C-termini, compared to isoform 3. Variants 1 and 4 encode the same protein. Isoform 1 is also known as HCam-3B. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205291 | PDE1C (Myc-DDK-tagged)-Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4 |
CNY 7,080.00 |
|
| RC205291L1 | Lenti ORF clone of Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4, Myc-DDK-tagged |
CNY 9,480.00 |
|
| RC205291L2 | Lenti ORF clone of Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RC205291L3 | Lenti ORF clone of Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205291L4 | Lenti ORF clone of Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RG205291 | PDE1C (tGFP-tagged) - Human phosphodiesterase 1C, calmodulin-dependent 70kDa (PDE1C), transcript variant 4 |
CNY 8,680.00 |
