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KCNMB3 (NM_171828) Human Untagged Clone
CAT＃: SC123922
KCNMB3 (untagged)-Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1
CNY 2,400.00
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMBL; SLO-BETA-3; SLOBETA3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC123922 sequence for NM_171828 edited (data generated by NextGen Sequencing)
ATGCAGCCCTTCAGCATCCCCGTGCAAATCACACTTCAGGGCAGCCGGAGGCGCCAGGGG AGGACAGCCTTTCCTGCCTCAGGGAAGAAGAGAGAGACAGACTACAGTGATGGAGACCCA CTAGATGTGCACAAGAGGCTGCCATCCAGTACTGGAGAGGACCGAGCCGTGATGCTGGGG TTTGCCATGATGGGCTTCTCAGTCCTAATGTTCTTCTTGCTCGGAACAACCATTCTAAAG CCTTTTATGCTCAGCATTCAGAGAGAAGAATCGACCTGCACTGCCATCCACACAGATATC ATGGACGACTGGCTGGACTGTGCCTTCACCTGTGGTGTGCACTGCCACGGTCAGGGGAAG TACCCGTGTCTTCAGGTGTTTGTGAACCTCAGCCATCCAGGTCAGAAAGCTCTCCTACAT TATAATGAAGAGGCTGTCCAGATAAATCCCAAGTGCTTTTACACACCTAAGTGCCACCAA GATAGAAATGATTTGCTCAACAATGCTCTGGACATAAAAGAATTCTTCGATCACAAAAAT GGAACCCCCTTTTCATGCTTCTACAGTCCAGCCAGCCAATCTGAAGATGTCATTCTTATA AAAAAGTATGACCAAATGGCTATCTTCCACTGTTTATTTTGGCCTTCACTGACTCTGCTA GGTGGTGCCCTGATTGTTGGCATGGTGAGATTAACACAACACCTGTCCTTACTGTGTGAA AAATATAGCACTGTAGTCAGAGATGAGGTAGGTGGAAAAGTACCTTATATAGAACAGCAT CAGTTCAAACTGTGCATTATGAGGAGGAGCAAAGGAAGAGCAGAGAAATCTTAA Clone variation with respect to NM_171828.1 151 g=>a;503 g=>a >OriGene 5' read for NM_171828 unedited
CCACTCACTATATGGCGGCCGCGCAGCAGACCACGCAGGTCCTTCTTGATCATCTAGAAC TGACCGCTCCGCCTTGCCAGGAGTCTGCAGAACCACGTGGCTAGCCTGCCTGAAGTTCTC ACCTCTCCAGGAAGGCGGGGGGCTTCTAATGGCTGCAGCTGCGCTGGGGGCTGGGGGCTC CCGCTGGGACTCCACTTCCGTGGATGTCTAAGCTTCACCTTTCTTGCGCCCGCAGGGGCA TGACTCAGGTGAAAGGGAGCCATTTTCTCAGACCCCTGGCCTCATGCAGCCCTTCAGCAT CCCCGTGCAAATCACACTTCAGGGCAGCCGGAGGCGCCAGGGGAGGACAGCCTTTCCTGC CTCAGGGAAGAAGAGAGAGACAGACTACAGTGATGGAGACCCACTAGATGTGCACAAGAG GCTGCCATCCAGTACTGGAGAGGACCGAGCCGTGATGCTGGGGTTTGCCATGATGGGCTT CTCAGTCCTAATGTTCTTCTTGCTCGGAACAACCATTCTAAAGCCTTTTATGCTCAGCAT TCAGAGAGAAGAATCGACCTGCACTGCCATCCACACAGATATCATGGACGACTGGCTGGA CTGTGCCTTCACCTGTGGTGTGCACTGCCACGGTCAGGGGAAGTACCCGTGTCTTCAGGT GTTTGTGAACCTCAGCCATCCAGGTCAGAAAGCTCTCCTACATTATAATGAAGAGGCTGT CCAGATAAATCCCAAGTGCTTTTACACACCTAAGTGCN >OriGene 3' read for NM_171828 unedited
TCCGGGCCAGGATAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGG AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTGGTTTTTTTTTTTTTT TTTTAAATTTTTTCCCACATGAAAATATGATACTTTAATTATTACCTTTTACATTGTTAG TTTGCAGACAGGCATAATTAGGTCCTCAGTTGCAGAAATCACAGACATCTGAAGGCCAGC ACTTTAATTTGGCCACCGTCTTAAGATTTCTCTGCTCTTCCTTTGCTCCTCCTCATAATG CACAGTTTGAACTGATGCTGTTCTATATAAGGTACTTTTCCACCTACCTCATCTCTGACT ACAGTGCTATATTTTTCACACAGTAAGGACAGGTGTTGTGTTAATCTCACCATGCCAACA ATCAGGGCACCACCTAGCAGAGTCAGTGAAGGCCAAAATAAACAGTGGAAGATAGCCATT TGGTCATACTTTTTTATAAGAATGACATCTTCAGATTGGCTGGCTGGACTGTAGAAGCAT GAAAAGGGGGTTCCATTTTTGTGATCGAAGAATTCTTTTATGTCCAGAGCATTGTTGAGC AAATCATTTCTATCTTGGTGGCACTTAGGTGTGTAAAAGCACTTGGGATTTATCTGGACA GCCTCTTCATTATAATGTAGGAGAGCTTTCTGACCTGGATGGCTGAGGTTCACAAACACC TGAAGACACGGGTACTTCCCCTGACCGTGGCAGTGCAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_171828 |
| Insert Size | 6200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_171828.1, NP_741979.1 |
| RefSeq Size | 1272 bp |
| RefSeq ORF | 834 bp |
| Locus ID | 27094 |
| UniProt ID | Q9NPA1 |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Protein Pathways | Vascular smooth muscle contraction |
| Gene Summary | MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009] Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region, and uses an alternate translational start codon, compared to variant 4. The resulting isoform (a) has a distinct N-terminus and is shorter than isoform d. CCDS Note: This CCDS representation is supported by accession AF204159.1 and data in PMID:10766764. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217576 | KCNMB3 (Myc-DDK-tagged)-Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1 |
CNY 2,400.00 |
|
| RC217576L3 | Lenti ORF clone of Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217576L4 | Lenti ORF clone of Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG217576 | KCNMB3 (tGFP-tagged) - Human potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1 |
CNY 4,000.00 |
