RGR (BC008094) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	RP44
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008094 edited TGAGGATGGCAGAGACCAGTGCCTTGCCCACCGGCTTCGGGGAGCTCGAGGTGCTGGCTG TGGGGATGGTGCTACTGGTGGAAGACCCCGGAGCTGCGGACTCCCTGCCACCTACTGGTG CTGAGCTTGGCTCTTGCGGACAGTGGGATCAGCCTGAATGCCCTCGTTGCAGCCACATCC AGCCTTCTCCGTGTCTCCCACAGGCGCTGGCCCTACGGCTCGGACGGCTGCCAGGCTCAC GGCTTCCAGGGCTTTGTGACAGCGTTGGCCAGCATCTGCAGCAGTGCAGCCATCGCATGG GGGCGTTATCACCACTACTGCACCCGCCAAAATGCTGCCATCGGTCTCATCATTTTGAGT GGCGATAGGTTAGCCCTCTTGTCCACTTGGCCTCAGAGCACTTCTCCCACTCCTTACATC CCAGCCCCTGCCCCTAATGCTCCCTTGGACCATCTTATACACACACACACACACACACAC ACACACACACACACACACACACACCACCTTCTCAGATAGCAACAGGCTTCTCTGCCTCAA TATAGAACAGTTAATCCCTGTGCCAGAGGCCTTAGATCAAAGCCCTTTCTATACTGAGAG CATGGCAGAGCAGTGTGAAGGCAGGCAAAGGGGAATGAGGAGGTCTGAATTCATCTACTC CATCCCTGGGTGGTTGTAGGCATGTCACCTTGGCCATCTGTTTCTAAAGCTGAAAGTCTG AGGCAGCACAATGGTCCAGGTAGATATTAATTATTGTGCCCACAGAGAATTGTTTGAACC TGGAAGGCAGAGGTTGCAGTGAGCTGAGATGGCACCACTGCACTCCAGCCTGGGCAACAG AATGAGACTCCGCCTCAATAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008094 unedited NAGGTCGCATATTGTATACGACTCACTATAGGCGGCCGCGNATTCATATCTGGTACCGGT CCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCCCACGCGTCCGTGAGGATGGCAG AGACCAGTGCCTTGCCCACCGGCTTCGGGGAGCTCGAGGTGCTGGCTGTGGGGATGGTGC TACTGGTGGAAGACCCCGGAGCTGCGGACTCCCTGCCACCTACTGGTGCTGAGCTTGGCT CTTGCGGACAGTGGGATCAGCCTGAATGCCCTCGTTGCAGCCACATCCAGCCTTCTCCGT GTCTCCCACAGGCGCTGGCCCTACGGCTCGGACGGCTGCCAGGCTCACGGCTTCCAGGGC TTTGTGACAGCGTTGGCCAGCATCTGCAGCAGTGCAGCCATCGCATGGGGGCGTTATCAC CACTACTGCACCCGCCAAAATGCTGCCATCGGTCTCATCATTTTGAGTGGCGATAGGTTA GCCCTCTTGTCCACTTGGCCTCAGAGCACTTCTCCCACTCCTTACATCCCAGCCCCTGCC CCTAATGCTCCCTTGGACCATCTTATACACACACACACACACACACACACACACACACAC ACACACACACACCACCTTCTCAGATAGCAACAGGCTTCTCTGCCTCAATATAGAACAGTT AATCCCTGTGCCAGAGGCCTTATATCAAAGCCCTTTCTATACTGAGAGCATGGCAGAGCA GTGTGAAGGCAGGCAAAGGGGAATGAGGAGGTCTGAATTCATCTACTCCATCCCTGGGTG GTTGTAGGCATGTCACCTTGGCCATCTGTTTCTAAAGCTGAAAGTCTGANGCAGCACAAT GGTCCAGGTAGATATTAATATTGTGCCCACAGGACAATGTTTGATCCTGGAAGCCAAAGT TGGCATGAGCTGAAATGGCACACTGCACTCATCCTGGGCACAGATGAGACTCCGCT
Restriction Sites	Please inquire
ACCN	BC008094
Insert Size	877 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC008094.1, AAH08094.1
RefSeq Size	877 bp
RefSeq ORF	363 bp
Locus ID	5995
Protein Families	Druggable Genome, GPCR, Transmembrane
Gene Summary	This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.