GPR62 (BC026357) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	G-protein coupled receptor; GPCR8; G protein-coupled receptor 62; KPG_005; MGC26943
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC026357 edited AGTACCATCTCCGACAGGGGCTGAGTTGCTGGAGCTGGGCTGGGGCAGGGGAGAAAGACA GCAGACTCATCCTTGCACCCCTCCATGGGCCTGGCCAAGCCCCCAAGAGGATGGCAGCCT GGGCGTCGGAGCCACCTCCTGGGCAGCCAATGAGGTGAGGGGCCGGAGGAGCAAGGGACA AGAGGAGCAGAGGACAGGTGATGGAAATCCTGCAGCTTTAGGCTCCATTCTGCCATCTAC ATCCCAGCGCAGGGTGAAGCCTGAGAGCCCAAATGGCCAACTCCACAGGGCTGAACGCCT CAGAAGTCGCAGGCTCGTTGGGGTTGATCCTGGCAGCTGTCGTGGAGGTGGGGGCACTGC TGGGCAACGGCGCGCTGCTGGTCGTGGTGCTGCGCACGCCGGGACTGCGCGACGCGCTCT ACCTGGCGCACCTGTGCGTCGTGGACCTGCTGGCGGCCGCCTCCATCATGCCGCTGGGCC TGCTGGCCGCACCGCCGCCCGGGCTGGGCCGCGTGCGCCTGGGCCCCGCGCCATGCCGCG CCGCTCGCTTCCTCTCCGCCGCTCTGCTGCCGGCCTGCACGCTCGGGGTGGCCGCACTTG GCCTGGCACGCTACCGCCTCATCGTGCACCCGCTGCGGCCAGGCTCGCGGCCGCCGCCTG TGCTCGTGCTCACCGCCGTGTGGGCCGCGGCGGGACTGCTGGGCGCGCTCTCCCTGCTCG GCCCGCCGCCCGCACCGCCCCCTGCTCCTGCTCGCTGCTCGGTCCTGGCTGGGGGCCTCG GGCCCTTCCGGCCGCTCTGGGCCCTGCTGGCCTTCGCGCTGCCCGCCCTCCTGCTGCTCG GCGCCTACGGCGGCATCTTCGTGGTGGCGCGTCGCGCTGCCCTGAGGCCCCCACGGCCGG CGCGCGGGTCCCGACTCCGCTCGGACTCTCTGGATAGCCGCCTTTCCATCTTGCCGCCAC TCCGGTCTCGCCTGCCCGGGGGCAAGGCGGCCCTGGCCCCAGCGCTGGCCGTGGGCCAAT TTGCAGCCTGCTGGCTGCCTTATGGCTGCGCGTGCCTGGCGCCCGCAGCGCGGGCCGCGG AAGCCGAAGCGGCTGTCACCTGGGTCGCCTACTCGGCCTTCGCGGCTCACCCCTTCCTGT ACGGGCTGCTGCAGCGCCCCGTGCGCTTGGCACTGGGCCGCCTCTCTCGCCGTGCACTGC CTGGACCTGTGCGGGCCTGCACTCCGCAAGCCTGGCACCCGCGGGCACTCTTGCAATGCC TCCAGAGACCCCCAGAGGGCCCTGCCGTAGGCCCTTCTGAGGCTCCAGAACAGACCCCCG AGTTGGCAGGAGGGCGGAGCCCCGCATACCAGGGGCCACCTGAGAGTTCTCTCTCCTGAG CAGGAGAAAGGAGGGTGGTTTCCGTGGGGGCTCATCCAACCCCTGCACAGGTCACAGCAG GTGCCCTGCTGGATATCTGGGTCTGGAACAGGAGGAGAAAGGGTGTCTGCTGCCTGGTGA GGCCCACGGACTTCTGAGAGCCAGGAATCCTGCGGTCTGGGCCCAACACTGCATAGCACT GTGCATAGGCCGACCCTTCCTTAGGCCTCAGCTTTCCCATCTGCACCCTGCAGCATCTCT AAGGGCCCCTCCAGCATAGGTGGTTTGTGAAACTCACAGGTGGTCCCCAGGCCAAGATGG GCAGGTGTCACAAAGAAGAGGGCCCTAAGGGCTCACAACCAAAGTGATCCGCCAAGCAGG GCAGTATCTGGGTTACAGCCACAGCAGGAAGAACCACTGGAGAGACACTCAGAAGGACTT CCCTGACATCTGCACCAAGGAGAGTCTGGACAAAGCTACTGAAACTCCTCCACCTGCTTC TAAAATGCCCAGAAGACAACTGGACCAGTTTGGTATTAGAAGTAGGAGGCTGGACGACTT CACCCCCAAAGGGTCCTGAAGCCCCAGAACTGGCATGTGGAAGGGGCTGAGGCCTAATTG AGGTTGGTGGATTCACACATGGGGGTCCTCCAGGACCTCAGCTGCACCCATTTTCTGGAG GTTTTGCTGCCCACAACACCAGTATTTCACAACTTCCTGGTCGCTGAGAATATTTATTCA AAAACAGGGATTGAAAAAACTGTAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC026357 unedited NNTTGATTTAATTTGTATACCACTTTCTATAGGCGGCCGCATAACTTCGTATAGCATACA TTATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGTA CCATCTCCGACGGGGCTGAGTTGCTGGAGCTGGGCTGGGGCAGGNGGAGAAAGACAGCAG ACTCATCCTTGCACCCCTCCATGGGCCTGGCCAAGCCCCCAAGAGGATGGCAGCCTGGGC GTCGGAGCCACCTCCTGGGCAGCCAATGAGGTGAGGGGCCGGAGGAGCAAGGGACAAGAG GAGCAGAGGACAGGTGATGGAAATCCTGCAGCTTTAGGCTCCATTCTGCCATCTACATCC CAGCGCAGGGTGAAGCCTGAGAGCCCAAATGGCCAACTCCACAGGGCTGAACGCCTCAGA AGTCGCAGGCTCGTTGGGGTTGATCCTGGCAGCTGTCGTGGAGGTGGGGGCACTGCTGGG CAACGGCGCGCTGCTGGTCGTGGTGCTGCGCACGCCGGGACTGCGCGACGCGCTCTACCT GGCGCACCTGTGCGTCGTGGACCTGCTGGCGGCCGCCTCCATCATGCCGCTGGGCCTGCT GGCCGCACCGCCGCCCGGGCTGGGCCGCGTGCGCCTGGGCCCCGCGCCATGCCGCGCCGC TCGCTTCCTCTCCGCCGCTCTGCTGCCGGCCTGCACGCTCGGGGGTGGCCGCACTTGGCC TGGCACGCTACCGNCTCATCGTGCACCCGCTGCCGCCAGGCTCGCGGCCGCCGCCTGTGC TCGTGCTCACGCCGTGTGGCCCGCGCGGGACTGCTGGGCGCGCTCTTCCTGGTNGGGCGC CGNCCGGACGGCCCCTGTTNCTGGTTGCTGCTCGGTCCTGGCTGGGGGCCTCCGGCCCC
Restriction Sites	Please inquire
ACCN	BC026357
Insert Size	2139 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC026357.1, AAH26357.1
RefSeq Size	2139 bp
RefSeq ORF	1104 bp
Locus ID	118442
Protein Families	Druggable Genome, GPCR, Transmembrane
Gene Summary	Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).[UniProtKB/Swiss-Prot Function]

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