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PPP2R1B (NM_181699) Human Untagged Clone
CAT＃: SC123371
PPP2R1B (untagged)-Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2
CNY 4,896.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PP2A-Abeta; PR65B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_181699 edited
AGGAGCAGGAGGAGAAAGAACATGGCGGGCGCATCAGAGCTCGGGACCGGCCCAGGAGCA GCGGGTGGAGATGGAGATGATTCGCTATACCCGATCGCGGTTTTAATCGACGAGCTCCGC AATGAAGACGTGCAGCTCCGACTCAACAGTATTAAGAAGTTATCAACAATTGCCCTAGCA CTTGGAGTAGAAAGGACCCGAAGTGAATTGTTGCCATTTCTTACAGATACAATTTATGAT GAAGATGAGGTACTATTAGCTCTTGCTGAGCAGCTGGGAAATTTCACTGGCCTAGTGGGA GGTCCTGACTTTGCCCACTGTCTGCTGCCTCCTTTGGAAAATCTGGCAACTGTGGAAGAG ACTGTTGTTCGTGACAAGGCTGTGGAGTCCCTGAGACAGATCTCCCAGGAGCATACTCCT GTTGCTCTGGAAGCTTATTTTGTACCTCTGGTGAAACGCTTAGCAAGTGGGGATTGGTTC ACCTCTCGCACATCTGCATGTGGTTTGTTCAGCGTTTGCTATCCCAGGGCATCAAATGCT GTTAAAGCAGAAATCAGACAGCAATTCCGTTCCTTGTGCTCAGATGACACACCAATGGTA CGACGTGCTGCTGCTTCCAAATTGGGTGAATTTGCAAAAGTTTTGGAATTAGACAGTGTG AAAAGTGAAATTGTTCCACTGTTCACTAGTCTAGCTTCAGATGAACAGGATTCAGTGCGC CTCCTTGCTGTGGAAGCTTGTGTCAGTATTGCCCAGTTATTGTCTCAGGATGACCTTGAG ACTTTGGTGATGCCTACACTTCGACAAGCAGCAGAAGATAAATCTTGGCGCGTTCGCTAT ATGGTGGCTGACAGATTTTCAGAGCTCCAGAAAGCCATGGGTCCTAAAATCACCCTAAAT GACCTCATCCCCGCCTTTCAGAACCTACTTAAAGACTGTGAAGCTGAAGTCCGGGCTGCT GCTGCCCACAAAGTAAAAGAACTTGGTGAGAACTTGCCCATTGAAGATAGAGAGACCATA ATTATGAATCAAATTCTGCCTTATATAAAGGAATTAGTATCCGATACCAATCAACATGTC AAATCGGCTCTAGCTTCTGTAATTATGGGATTGTCTACTATTTTGGGCAAAGAAAATACC ATTGAACATCTTCTACCTCTTTTCTTAGCTCAGTTAAAGGATGAGTGTCCTGACGTTCGT TTGAATATCATCTCCAATTTGGATTGTGTAAATGAAGTGATTGGAATCCGTCAGCTCTCT CAGTCTCTCCTTCCTGCCATAGTGGAGCTGGCAGAAGATGCCAAATGGAGGGTCCGCCTG GCCATCATTGAGTATATGCCGCTGCTGGCAGGCCAGCTGGGTGTGGAATTCTTTGATGAA AAGCTGAATTCTTTATGTATGGCTTGGCTCGTGGACCATGTATACGCCATCCGAGAAGCT GCCACCAACAACCTCATGAAACTAGTTCAGAAGTTTGGTACAGAGTGGGCCCAAAATACT ATTGTTCCCAAAGTGTTAGTAATGGCAAATGATCCTAATTACTTGCATAGAATGACCACT TTATTCTGCATTAATGCACTGTCTGAGGCCTGTGGTCAGGAAATAACTACTAAGCAAATG CTGCCCATCGTATTAAAAATGGCAGGAGACCAAGTAGCAAATGTTCGCTTCAATGTGGCC AAATCTCTACAAAAGATTGGACCAATTCTAGATACCAATGCTTTACAGGGAGAAGTGAAG CCAGTACTACAGAAGTTAGGTCAAGATGAAGACATGGATGTCAAATACTTTGCACAGGAA GCTATAAGTGTGGTGGCACAAAGGCTGAGGAAGCTAGAATTTCCTGTGAAGGACAGTGGA GAACCCAGTGTCCCTCGGGCTGACAAGAACCACTTCCCAAGACCCACAGTGCCTGGAGAG GACATGGGGAAGGGACCAGTGTATCAGTTGCGTGGAGATACTAGAGACACACTTGCCCAG CTGGGAATTGCAGAGCTAGTGCATTTCTCCCAAAGCACAGACTAATACCCCAGATTTAAA AAAAGAACATAAAAAATAAAGTACCACACATATTACAAAAAAAAAAAAAAAA >OriGene 5' read for NM_181699 unedited
GGCCGAATACACTTCCTATAGCATACATTATACAATANTTATGGTAGTCAGGCCAAGGGG GGCGCGCGGCGGGGATTCATAAAAAGCGGAGGAGCAGGAGGAGAAAGAACATGGCGGGCG CATCAGAGCTCGGGACCGGCCCAGGAGCAGCGGGTGGAGATGGAGATGATTCGCTATACC CGATCGCGGTTTTTATTTACGAGCTCCGCAATGAAGACGTGGGGGGGCGACTCAACAGTA TTAAGAAGTTATCAACAATTGCCCTAGCACTTGGAGTAGAAAGGACCCGAAGTGAATTGT TGCCATTTCTTACAGATACAATTTATGATGAAGATGAGGTACTATTAGCTCTTGCTGAGC AGCTGGGAAATTTCACTGGCCTAGTGGGAGGTCCTGACTTTGCCCACTGTCTGCTGCCTC CTTTGGAAAATCTGGCAACTGTGGAAGAGACTGTTGTTCGTGACAAGGCTGTGGAGTCCC TGAGACAGATCTCCCAGGAGCATACTCCTGTTGCTCTGGAAGCTTATTTTGTACCTCTGG TGAAACGCTTAGCAAGTGGGGATTGGTTCACCTCTCGCACATCTGCGTGTGGTTTGGTCA GCGTTTGCTATCCCAGGGCATCAAATGCTGTTAAAGCAGAAATCAGACAGCAATTCCGTT CCTTGTGCTCAGATGACACACCAATGGTACGACGTGCTGCTGCTTCCAAATTGGGTGAAT TGCAAAAGTGTTGGAATTAGACAGTGTGAAAAGGGAATTGTTGCCCTGTTCGCTAGTCTA GCTCCAGATGAACGGGATTCAGTGCGCCTCCTTGGTGGGAGAACTTGGGTCATTATTGCC CAATTTTGGCTCAGGGGAACCTTGAAACTTGGGGGAGCGCACCTTCCAACAGCGGGN |
| Restriction Sites | Please inquire |
| ACCN | NM_181699 |
| Insert Size | 2097 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_181699.1, NP_859050.1 |
| RefSeq Size | 2139 bp |
| RefSeq ORF | 2004 bp |
| Locus ID | 5519 |
| UniProt ID | P30154 |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| Protein Pathways | Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway |
| Gene Summary | This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] Transcript Variant: This variant (2) differs in the 3' UTR and the 3' coding region, compared to variant 1. The resulting isoform (b) contains a longer and distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Protein phosphatase 2A is essential to maintain active Wnt signaling and its Aß tumor suppressor subunit is not expressed in colon cancer cells
,Carmen Figueroa-Aldariz, M;Castañeda-Patlán, MC;Santoyo-Ramos, P;Zentella, A;Robles-Flores, M;,
Mol. Carcinog.
,PubMed ID 25252130
[PPP2R1B]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205346 | PPP2R1B (Myc-DDK-tagged)-Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2 |
CNY 4,888.00 |
|
| RC205346L1 | Lenti ORF clone of Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205346L2 | Lenti ORF clone of Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC205346L3 | Lenti ORF clone of Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205346L4 | Lenti ORF clone of Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2, mGFP tagged |
CNY 7,288.00 |
|
| RG205346 | PPP2R1B (tGFP-tagged) - Human protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2 |
CNY 6,488.00 |
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