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Prune homolog 2 (PRUNE2) (NM_138818) Human Untagged Clone
CAT＃: SC123158
PRUNE2 (untagged)-Human prune homolog 2 (Drosophila) (PRUNE2), transcript variant 2
CNY 2,400.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BMCC1, BNIPXL, C9orf65, KIAA0367, A214N16.3, bA214N16.3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_138818 edited
GGAGGGAGCAGTCGGTCGCTGCGCCCCGGCGGGCCACTTTCCCGGGACCCCGCTCGTCTT CCTTGGGCCGAGATTTTCCACTGCGCCCCTCCGAGTACCCGGGTTCCAAACCCCTAGCCA CGACATGGAAGAATTTTTGCAACGCGCCAAATCTAAACTGAATCGAAGCAAACGCTTGGA GAAGGTCCATGTGGTTATTGGGCCTAAATCGTGTGACTTGGATTCTCTCATTTCTACCTT CACATATGCTTACTTTCTAGACAAGGTCAGTCCACCAGGGGTTCTGTGTTTACCAGTGCT GAACATACCAAGAACTGAATTCAACTACTTCACCGAGACGAGGTTTATTTTAGAAGAGCT AAATATTTCCGAATCATTCCACATATTCCGGGATGAAATTAACCTGCATCAGCTAAATGA TGAAGGGAAGTTATCGATAACACTTGTTGGCAGCAGTGTGCTGGCGAGTGAAGACAAAAC TTTAGAATCAGCAGTTGTCAAAGTCATTAATCCGGTTGAGCAGAGCGATGCCAACGTTGA GTTCCGAGAGTCTTCCTCTTCTCTCGTGCTAAAGGAGATTCTCCAAGAGGCTCCTGAGCT CATCACCGAGCAACTGGCTCATCGCCTCAGAGGTAGCATTCTTTTCAAGTGGATGACCAT GGAATCAGAGAAGATCTCAGAGAAGCAGGAGGAAATTCTTTCTATCCTGGAAGAAAAATT TCCTAACTTGCCTCCAAGAGAGGACATCATCAACGTCCTACAGGAGACCCAGTTCAGTGC TCAGGGTTTAAGTATTGAACAGACAATGTTGAAAGATCTAAAGGAGCTGTCAGATGGAGA AATAAAAGTGGCCATTAGTACTGTGAGCATGAACCTTGAGGTAAGGGTGGGAATGCTTTT TTAGCATTGATTGATTTCCCACAATTGCAGTCTGAGCAACTGGAATGTAACTCTCTCCAT TGGATAAGTCCATGATAGTCCTTTGCTTCTTTGTGATACATTTGACTTGGAATATAGTGG CAGGTTATTATTTGGGTGAAAACACTATGCTAAGTCAATGAAAAATGCCAAACCTGGATT CTCAAGATGAATGCTCTTTCATTCATCTCAGTAAAACAAAGCCTAAAACAAACACTCAGA TGTGGGTGTATATTTAACCTGTTTAATAGCAATTATGATATGTGTGATTAGGTTCACTTC CATATTTTCTGTGTACCACCCTGTATTGTTCATAGAACTTTTCTTAAAAAAAAAAAAAAA AAAA >OriGene 5' read for NM_138818 unedited
NNGGTACCGTTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACNGGG GAGGGAGCAGTCGGTCGCTGCGCCCCGGCGGGCCACTTTCCCGGGACCCCGCTCGTCTTC CTTGGGCCGAGATTTTCCACTGCGCCCCTCCGAGTACCCGGGTTCCAAACCCCTAGCCAC GACATGGGAAGAATTTTTGCAACGCGCCAAATCTAAACTGAATCGAAGCAAACGCTTGGA GAAGGTCCATGTGGTTATTGGGCCTAAATCGTGTGACTTGGATTCTCTCATTTCTACCTT CACATATGCTTACTTTCTAGACAAGGTCAGTCCACCAGGGGTTCTGTGTTTACCAGTGCT GAACATACCAAGAACTGAATTCAACTACTTCACCGAGACGAGGTTTATTTTAGAAGAGCT AAATATTTCCGAATCATTCCACATATTCCGGGATGAAATTAACCTGCATCAGCTAAATGA TGAAGGGAAGTTATCGATAACACTTGTTGGCAGCAGTGTGCTGGCGAGTGAAGACAAAAC TTTAGAATCAGCAGTTGTCAAAGTCATTAATCCGGTTGAGCAGAGCGATGCCAACGTTGA GTTCCGAGAGTCTTCCTCTTCTCTCGTGCTAAAGGAGATTCTCCAAGAGGCTCCTGAGCT CATCACCGAGCAACTGGCTCATCGCCTCAGAGGTAGCATTCTTTTCAAGTGGATGACCAT GGAATCAGAGAAGATCTCAGAGAAGCAGGAGGAAATTCTTTCTATCCTGGGAGANAAATT TCCTAACTTGCCTCCAAGAGAGGACATCATCAACCGTCCTACAGGGAGACCCAGTTCAGT GCTCAGGGTTTTAAGTATTGAACAGGACATGTTGGAAAGATCTAAAAGAGCTGTCAGAT |
| Restriction Sites | Please inquire |
| ACCN | NM_138818 |
| Insert Size | 1273 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138818.2, NP_620173.1 |
| RefSeq Size | 1264 bp |
| RefSeq ORF | 780 bp |
| Locus ID | 158471 |
| Gene Summary | The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] Transcript Variant: This variant (2) differs in the 3' UTR, and lacks several exons in the 3' coding region, compared to variant 1. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 1. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205712 | PRUNE2 (Myc-DDK-tagged)-Human prune homolog 2 (Drosophila) (PRUNE2), transcript variant 2 |
CNY 2,400.00 |
|
| RC205712L3 | Lenti ORF clone of Human prune homolog 2 (Drosophila) (PRUNE2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205712L4 | Lenti ORF clone of Human prune homolog 2 (Drosophila) (PRUNE2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG205712 | PRUNE2 (tGFP-tagged) - Human prune homolog 2 (Drosophila) (PRUNE2), transcript variant 2 |
CNY 4,000.00 |
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