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Lin28 (LIN28A) (NM_024674) Human Untagged Clone
CAT＃: SC122965
LIN28A (untagged)-Human lin-28 homolog A (LIN28A)
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_024674 edited
GTGCGGGGGAAGATGTAGCAGCTTCTTCTCCGAACCAACCCTTTGCCTTCGGACTTCTCC GGGGCCAGCAGCCGCCCGACCAGGGGCCCGGGGCCACGGGCTCAGCCGACGACCATGGGC TCCGTGTCCAACCAGCAGTTTGCAGGTGGCTGCGCCAAGGCGGCAGAAGAGGCGCCCGAG GAGGCGCCGGAGGACGCGGCCCGGGCGGCGGACGAGCCTCAGCTGCTGCACGGTGCGGGC ATCTGTAAGTGGTTCAACGTGCGCATGGGGTTCGGCTTCCTGTCCATGACCGCCCGCGCC GGGGTCGCGCTCGACCCCCCAGTGGATGTCTTTGTGCACCAGAGTAAGCTGCACATGGAA GGGTTCCGGAGCTTGAAGGAGGGTGAGGCAGTGGAGTTCACCTTTAAGAAGTCAGCCAAG GGTCTGGAATCCATCCGTGTCACCGGACCTGGTGGAGTATTCTGTATTGGGAGTGAGAGG CGGCCAAAAGGAAAGAGCATGCAGAAGCGCAGATCAAAAGGAGACAGGTGCTACAACTGT GGAGGTCTAGATCATCATGCCAAGGAATGCAAGCTGCCACCCCAGCCCAAGAAGTGCCAC TTCTGCCAGAGCATCAGCCATATGGTAGCCTCATGTCCGCTGAAGGCCCAGCAGGGCCCT AGTGCACAGGGAAAGCCAACCTACTTTCGAGAGGAAGAAGAAGAAATCCACAGCCCTACC CTGCTCCCGGAGGCACAGAATTGAGCCACAATGGGTGGGGGCTATTCTTTTGCTATCAGG AAGTTTCGAGGAGCAGGCAGAGTGGAGAAAGTGGGAATAGGGTGCATTGGGGCTAGTTGG CACTGCCATGTATCTCAGGCTTGGGTTCACACCATCACCCTTTCTTCCCTCTAGGTGGGG GGAAAGGGTGAGTCAAAGGAACTCCAACCATGCTCTGTCCAAATGCAAGTGAGGGTTCTG GGGGCAACCAGGAGGGGGGAATCACCCTACAACCTGCATACTTTGAGTCTCCATCCCCAG AATTTCCAGCTTTTGAAAGTGGCCTGGATAGGGAAGTTGTTTTCCTTTTAAAGAAGGATA TATAATAATTCCCATGCCAGAGTGAAATGATTAAGTATAAGACCAGATTCATGGAGCCAA GCCACTACATTCTGTGGAAGGAGATCTCTCAGGAGTAAGCATTGTTTTTTTTTCACATCT TGTATCCTCATACCCACTTTTGGGATAGGGTGCTGGCAGCTGTCCCAAGCAATGGGTAAT GATGATGGCAAAAAGGGTGTTTGGGGGAACAGCTGCAGACCTGCTGCTCTATGCTCACCC CCGCCCCATTCTGGGCCAATGTGATTTTATTTATTTGCTCCCTTGGATACTGCACCTTGG GTCCCACTTTCTCCAGGATGCCAACTGCACTAGCTGTGTGCGAATGACGTATCTTGTGCA TTTTAACTTTTTTTCCTTAATATAAATATTCTGGTTTTGTATTTTTGTATATTTTAATCT AAGGCCCTCATTTCCTGCACTGTGTTCTCAGGTACATGAGCAATCTCAGGGATAGCCAGC AGCAGCTCCAGGTCTGCGCAGCAGGAATTACTTTTTGTTGTTTTTGCCACCGTGGAGAGC AACTATTTGGAGTGCACAGCCTATTGAACTACCTCATTTTTGCCAATAAGAGCTGGCTTT TCTGCCATAGTGTCCTCTTGAAACCCCCTCTGCCTTGAAAATGTTTTATGGGAGACCAGG TTTTAACTGGGTGGCCCCATGACTTGATTGCCTTCTACTGGAAGATTGGGAATTAGTCTA AACAGGAAATGGTGGTACACAGAGGCTAGGAGAGGCTGGGCCCGGTGAAAAGGCCAGAGA GCAAGCCAAGATTAGGTGAGGGTTGTCTAATCCTATGGCACAGGACGTGCTTTACATCTC CAGATCTGTTCTTCACCAGATTAGGTTAGGCCTACCATGTGCCACAGGGTGTGTGTGTGT TTGTAAAACTAGAGTTGCTAAGGATAAGTTTAAAGACCAATACCCCTGTACTTAATCCTG TGCTGTCGAGGGATGGATATATGAAGTAAGGTGAGATCCTTAACCTTTCAAAATTTTCGG GTTCCAGGGAGACACACAAGCGAGGGTTTTGTGGTGCCTGGAGCCTGTGTCCTGCCCTGC TACAGTAGTGATTAATAGTGTCATGGTAGCTAAAGGAGAAAAAGGGGGTTTCGTTTACAC GCTGTGAGATCACCGCAAACCTACCTTACTGTGTTGAAACGGGACAAATGCAATAGAACG CATTGGGTGGTGTGTGTCTGATCCTGGGTTCTTGTCTCCCCTAAATGCTGCCCCCCAAGT TACTGTATTTGTCTGGGCTTTGTAGGACTTCACTACGTTGATTGCTAGGTGGCCTAGTTT GTGTAAATATAATGTATTGGTCTTTCTCCGTGTTCTTTGGGGGTTTTGTTTACAAACTTC TTTTTGTATTGAGAGAAAAATAGCCAAAGCATCTTTGACAGAAGGTTCTGCACCAGGCAA AAAGATCTGAAACATTAGTTTGGGGGGCCCTCTTCTTAAAGTGGGGATCTTGAACCATCC TTTCTTTTGTATTCCCCTTCCCCTATTACCTATTAGACCAGATCTTCTGTCCTAAAAACT TGTCTTCTACCCTGCCCTCTTTTCTGTTCACCCCCAAAAGAAAACTTACACACCCACACA CATACACATTTCATGCTTGGAGTGTCTCCACAACTCTTAAATGATGTATGCAAAAATACT GAAGCTAGGAAAACCCTCCATCCCTTGTTCCCAACCTCCTAAGTCAAGACCATTACCATT TCTTTCTTTCTTTTTTTTTTTTTTTAAAATGGAGTCTCGCTGTGTCGCCCAGGCTGGAGT GCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGTTACAGAGCAAGACTCTGTCTC AAACAAAACAAAACAAAACAAAAACACACTACTGTATTTTGGATGGATCAAACCTCCTTA ATTTTAATTTCTAATCCTAAAGTAAAGAGATGCAATTGGGGGCCTTCCATGTAGAAAGTG GGGTCAGGAGGCCAAGAAAGGGAATATGAATGTATATCCAAGTCACTCAGGAACTTTTAT GCAGGTGCTAGAAACTTTATGTCAAAGTGGCCACAAGATTGTTTAATAGGAGACGAACGA ATGTAACTCCATGTTTACTGCTAGAAACCAAAGCTTTGTGTAAAATCTTGAATTTATGGG GCGGGAGGGTAGGAAAGCCTGTACCTGTCTGTTTTTTTCCTGATCCTTTTCCCTCATTCC TGAACTGCAGGAGACTGAGCCCCTTTGGGCTTTGGTGACCCCATCACTGGGGTGTGTTTA TTTGATGGTTGATTTTGCTGTACTGGGTACTTCCTTTCCCATTTTCTAATCATTTTTTAA CACAAGCTGACTCTTCCCTTCCCTTCTCCTTTCCCTGGAAAAATACAATGAATAAATAAA GACTTATTGGTACTCAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_024674 unedited
NNNNCCCAGTACACAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGG TGCGGGGGAAGAGTAGCAGCTTCTTCTCCGAACCAACCCTTTGCCTTCGGACTTCTCCGG GGCCAGCAGCCGCCCGANAGGGGCCCGGGGCCACGGGCTCAGCCGACGACCATGGGCTCC GTGTCCAACCAGCAGTTTGCAGGTGGCTGCGCCAAGGCGGCAGAAGAGGCGCCCGAGGAG GCGCCGGAGGACGCGGCCCGGGCGGCGGACGAGCCTCAGCTGCTGCACGGTGCGGGCATC TGTAAGTGGTTCAACGTGCGCATGGGGTTCGGCTTCCTGTCCATGACCGCCCGCGCCGGG GTCGCGCTCGACCCCCCAGTGGATGTCTTTGTGCACCAGAGTAAGCTGCACATGGAAGGG TTCCGGAGCTTGAAGGAGGGTGAGGCAGTGGAGTTCACCTTTAAGAAGTCAGCCAAGGGT CTGGAATCCATCCGTGTCACCGGACCTGGTGGAGTATTCTGTATTGGGAGTGAGAGGCGG CCAAAAGGAAAGAGCATGCAGAAGCGCAGATCAAAAGGAGACAGGTGCTACAACTGTGGA GGTCTAGATCATCATGCCAAGGAATGCAAGCTGCCACCCCAGCCCAAGAAGTGCCACTTC TGCCAGAGCATCAGCCATATGGTAGCCTCATGTCCGCTGAAAGCCCAGCAGGGCCCTAGT GCACAGGGAAAGCCAACCTACTTTCGAGAGGAAGAAANAAGAAATCCACAGCCCTACCCT GCTCCCGGAGGCACAGAATTGAGCCACATGGGTGGGGGCTATTCTTTTGCTATCAGGAAG TTTCGAGGACAGGCAGAGN |
| Restriction Sites | Please inquire |
| ACCN | NM_024674 |
| Insert Size | 3522 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_024674.3, NP_078950.1 |
| RefSeq Size | 3513 bp |
| RefSeq ORF | 630 bp |
| Locus ID | 79727 |
| UniProt ID | Q9H9Z2 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition
,null,
The FASEB Journal
,PubMed ID 33200449
[LIN28A]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203397 | LIN28A (Myc-DDK-tagged)-Human lin-28 homolog A (LIN28A) |
CNY 2,400.00 |
|
| RC203397L1 | Lenti ORF clone of Human lin-28 homolog A (LIN28A), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC203397L2 | Lenti ORF clone of Human lin-28 homolog A (LIN28A), mGFP tagged |
CNY 4,800.00 |
|
| RC203397L3 | Lenti ORF clone of Human lin-28 homolog A (LIN28A), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC203397L4 | Lenti ORF clone of Human lin-28 homolog A (LIN28A), mGFP tagged |
CNY 4,800.00 |
|
| RG203397 | LIN28A (tGFP-tagged) - Human lin-28 homolog A (LIN28A) |
CNY 4,000.00 |
