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RHBDF2 (NM_024599) Human Untagged Clone
CAT＃: SC122961
RHBDF2 (untagged)-Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1
CNY 6,280.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | iRhom2; RHBDL5; RHBDL6; TEC; TOC; TOCG |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_024599 edited
GCCGCTCGCAGGCGCCGCACGGAGTTGCGTCCCGGGGACTTGGGGCCGCAGGGAGCTGTG AGTACCCAGGAAGCTGCACCGTGTGGCCTGGAGCTGTCTATCTGTCCTTCCAGCCACCTG TCTGTCCAGCCACCCTTCCACAGACTGAGGCTTGACACCGGAGCATCTGTACAGAGCAAG GAGAAGACAAGAACATGCTCTAAAGCCCTTCACAGCAAGACCCAGGAAGCCGCGGGCAAA CTCAGACTCGAAGCCCTCCCGCCTCCTGCCCACAATGGCCTCTGCTGACAAGAATGGCGG GAGCGTGTCCTCTGTGTCCAGCAGCCGCCTGCAGAGCCGGAAGCCACCCAACCTCTCCAT CACCATCCCGCCACCCGAGAAAGAGACCCAGGCCCCTGGCGAGCAGGACAGCATGCTGCC TGAGGGTTTTCAGAATAGGAGGCTAAAGAAAAGCCAGCCCAGGACCTGGGCTTCACACAC CACCGCCTGCCCTCCCTCCTTCCTCCCCAAGAGGAAGAACCCAGCCTACTTGAAGAGCGT CAGCCTCCAGGAGCCACGCAGCCGATGGCAGGAGAGTTCAGAGAAGCGCCCTGGCTTCCG CCGCCAGGCCTCACTGTCCCAGAGCATCCGCAAGGGCGCAGCCCAGTGGTTTGGAGTCAG CGGCGACTGGGAGGGGCAGCGGCAGCAGTGGCAGCGCCGCAGCCTGCACCACTGCAGCAT GCGCTACGGCCGCCTGAAGGCCTCGTGCCAGCGTGACCTGGAGCTCCCCAGCCAGGAGGC ACCGTCCTTCCAGGGCACTGAGTCCCCAAAGCCCTGCAAGATGCCCAAGATTGTGGATCC GCTGGCCCGGGGCCGGGCCTTCCGCCACCCGGAGGAGATGGACAGGCCCCACGCCCTGCA CCCACCGCTGACCCCCGGAGTCCTGTCCCTCACCTCCTTCACCAGTGTCCGTTCTGGCTA CTCCCACCTGCCACGCCGCAAGAGAATGTCTGTGGCCCACATGAGCTTGCAAGCTGCCGC TGCCCTCCTCAAGGGGCGCTCGGTGCTGGATGCCACCGGACAGCGGTGCCGGGTGGTCAA GCGCAGCTTTGCCTTCCCGAGCTTCCTGGAGGAGGATGTGGTCGATGGGGCAGACACGTT TGACTCCTCCTTTTTTAGTAAGGAAGAAATGAGCTCCATGCCTGATGATGTCTTTGAGTC CCCCCCACTCTCTGCCAGCTACTTCCGAGGGATCCCACACTCAGCCTCCCCTGTCTCCCC CGATGGGGTGCAAATCCCTCTGAAGGAGTATGGCCGAGCCCCAGTCCCCGGGCCCCGGCG CGGCAAGCGCATCGCCTCCAAGGTGAAGCACTTTGCCTTTGATCGGAAGAAGCGGCACTA CGGCCTCGGCGTGGTGGGCAACTGGCTGAACCGCAGCTACCGCCGCAGCATCAGCAGCAC TGTGCAGCGGCAGCTGGAGAGCTTCGACAGCCACCGGCCCTACTTCACCTACTGGCTGAC CTTCGTCCATGTCATCATCACGCTGCTGGTGATTTGCACGTATGGCATCGCACCCGTGGG CTTTGCCCAGCACGTCACCACCCAGCTGGTGCTGCGGAACAAAGGTGTGTACGAGAGCGT GAAGTACATCCAGCAGGAGAACTTCTGGGTTGGCCCCAGCTCGATTGACCTGATCCACCT GGGGGCCAAGTTCTCACCCTGCATCCGGAAGGACGGGCAGATCGAGCAGCTGGTGCTGCG CGAGCGAGACCTGGAGCGGGACTCAGGCTGCTGTGTCCAGAATGACCACTCCGGATGCAT CCAGACCCAGCGGAAGGACTGCTCGGAGACTTTGGCCACTTTTGTCAAGTGGCAGGATGA CACTGGGCCCCCCATGGACAAGTCTGATCTGGGCCAGAAGCGGACTTCGGGGGCTGTCTG CCACCAGGACCCCAGGACCTGCGAGGAGCCAGCCTCCAGCGGTGCCCACATCTGGCCCGA TGACATCACTAAGTGGCCGATCTGCACAGAGCAGGCCAGGAGCAACCACACAGGCTTCCT GCACATGGACTGCGAGATCAAGGGCCGCCCCTGCTGCATCGGCACCAAGGGCAGCTGTGA GATCACCACCCGGGAATACTGTGAGTTCATGCACGGCTATTTCCATGAGGAAGCAACACT CTGCTCCCAGGTGCACTGCTTGGACAAGGTGTGTGGGCTGCTGCCCTTCCTCAACCCTGA GGTCCCAGATCAGTTCTACAGGCTCTGGCTGTCTCTCTTCCTACATGCTGGCGTGGTGCA CTGCCTCGTGTCTGTGGTCTTTCAAATGACCATCCTGAGGGACCTGGAGAAGCTGGCCGG CTGGCACCGTATCGCCATCATCTTCATCCTCAGTGGCATCACAGGCAACCTCGCCAGTGC CATCTTTCTCCCATACCGGGCAGAGGTGGGCCCGGCCGGCTCACAGTTCGGCCTCCTCGC CTGCCTCTTCGTGGAGCTCTTCCAGAGCTGGCCGCTGCTGGAGAGGCCCTGGAAGGCCTT CCTCAACCTCTCGGCCATCGTGCTCTTCCTGTTCATCTGTGGCCTCCTGCCCTGGATCGA CAACATCGCCCACATCTTCGGCTTCCTCAGTGGCCTGCTGCTGGCCTTCGCCTTCCTGCC CTACATCACCTTCGGCACCAGCGACAAGTACCGCAAGCGGGCACTCATCCTGGTGTCACT GCTGGCCTTTGCCGGCCTCTTCGCCGCCCTCGTGCTGTGGCTGTACATCTACCCCATTAA CTGGCCCTGGATCGAGCACCTCACCTGCTTCCCCTTCACCAGCCGCTTCTGCGAGAAGTA TGAGCTGGACCAGGTGCTGCACTGACCGCTGGGCCACACGGCTGCCCCTCAGCCCTGCTG GAACAGGGTCTGCCTGCGAGGGCTGCCCTCTGCAGAGCGCTCTCTGTGTGCCAGAGAGCC AGAGACCCAAGACAGGGCCCGGGCTCTGGACCTGGGTGCCCCCCTGCCAGGCGAGGCTGA CTCCGCGTGAGATGGTTGGTTAAGGCGGGGTTTTTCTGGGGCGTGAGGCCTGTGAGATCC TGACCCAAGCTCAGGCACACCCAAGGCACCTGCCTCTCTGAGTCTTGGGTCTCAGTTCCT AATATCCCGCTCCTTGCTGAGACCATCTCCTGGGGCAGGGTCCTTTTCTTCCCAGGTCCT CAGCGCTGCCTCTGCTGGTGCCTTCTCCCCCACTACTACTGGAGCGTGCCCTTGCTGGGG ACGTGGCTGTGCCCTCAGTTGCCCCCAGGGCTGGGTGCCCACCATGCCCCTTCCTCTTTC TCCTCCTACCTCTGCCCTGTGAGCCCATCCATAAGGCTCTCAGATGGGACATTGTGGGAA AGGCTTTGGCCATGGTCTGGGGGCAGAGAACAAGGGGGGAGACACAAGTAGACCTCAGGT AGAACGACACTGGGCGGAGCCACCCCAGGGCCTGCTCCCAGGGAGTGCTCGAGGCGCATC AGGCCCGTTTTTTACCAGTTTATATCACGGTCTTCATTTTTAAAAGTAACGCTAACTTTG TAGGGACGATGTCTCATGGATTAAATAATATTCTTTATGGCAAAAAAAAAAAAAAA >OriGene 5' read for NM_024599 unedited
TTTTNGGGGACCTTGATTTGTAATACGACTTTACTATAGGGCGGCCGCGATTCCCGGGAT ATCGTCGACCCACGCGTCCGGCCGCTCGCAGGCGCCGCACGGAGTTGCGTCCCGGGGACT TGGGGCCGCAGGGAGCTGTGAGTACCCAGGAAGCTGCACCGTGTGGCCTGGAGCTGTCTA TCTGTCCTTCCAGCCACCTGTCTGTCCAGCCACCCTTCCACAGACTGAGGCTTGACACCG GAGCATCTGTACAGAGCAAGGAGAAGACAAGAACATGCTCTAAAGCCCTTCACAGCAAGA CCCAGGAAGCCGCGGGCAAACTCAGACTCGAAGCCCTCCCGCCTCCTGCCCACAATGGCC TCTGCTGACAAGAATGGCGGGAGCGTGTCCTCTGTGTCCAGCAGCCGCCTGCAGAGCCGG AAGCCACCCAACCTCTCCATCACCATCCCGCCACCCGAGAAAGAGACCCAGGCCCCTGGC GAGCAGGACAGCATGCTGCCTGAGGGTTTTCAGAATAGGAGGCTAAAGAAAAGCCAGCCC AGGACCTGNGCTTCACACACCACCGCCTGCCCTCCCTCCTTCCTCCCCAAGAGGAAGAAC CCAGCCTACTTGAAGAGCGTCAGCCTCCAGGAGCCACGCAGCCGATGGCAGGAGAGTTCA GAGAAGCGCCCTGGCTTCCGCCGCCAGGCCTCACTGTCCCAGAGCATCCGCAAGGGCGCA GCCCAGTGGTTTGGAGTCAGCGGCGACTGGGAGGGGGCAGCGCAGCAGTGGCAGCGCCGC AGCCTGCACCACTGCAGCATGCGCTACGGCCGCCTGAAGGCCTCGTGCCAGCGTGACCTG GAGCTCCNCAGCCAGGAGGCACCGTCCTTCCAGGCACTGAGTCCCCAAGCCCTGCAGATG |
| Restriction Sites | Please inquire |
| ACCN | NM_024599 |
| Insert Size | 3596 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_024599.2, NP_078875.2 |
| RefSeq Size | 3596 bp |
| RefSeq ORF | 2571 bp |
| Locus ID | 79651 |
| UniProt ID | Q6PJF5 |
| Protein Families | Protease, Transmembrane |
| Gene Summary | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
,null,
eLife
,PubMed ID 29897336
[RHBDF2]
|
|
FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex
,Künzel, U;Grieve, A;Meng, Y;Cowley, S;Freeman, M;,
bioRxiv
[RHBDF2]
|
|
Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16
,Maruthappu, T;Chikh, A;Fell, B;Delaney, PJ;Brooke, MA;Levet, C;Moncada-Pazos, A;Ishida-Yamamoto, A;Blaydon, D;Waseem, A;Leigh, IM;Freeman, M;Kelsell, DP;,
Nat Commun
,PubMed ID 28128203
[RHBDF2]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203923 | RHBDF2 (Myc-DDK-tagged)-Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1 |
CNY 6,272.00 |
|
| RC203923L1 | Lenti ORF clone of Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1, Myc-DDK-tagged |
CNY 8,672.00 |
|
| RC203923L2 | Lenti ORF clone of Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC203923L3 | Lenti ORF clone of Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203923L4 | Lenti ORF clone of Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG203923 | RHBDF2 (tGFP-tagged) - Human rhomboid 5 homolog 2 (Drosophila) (RHBDF2), transcript variant 1 |
CNY 7,872.00 |
