MOCOS (NM_017947) Human Untagged Clone
CAT#: SC122871
MOCOS (untagged)-Human molybdenum cofactor sulfurase (MOCOS)
CNY 9,768.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HMCS; MCS; MOS |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_017947 edited
ACTAGCCGGGGCCATGGCCGGCGCGGCGGCGGAGTCAGGGCGGGAGCTGTGGACCTTCGC GGGTTCCCGGGACCCGAGCGCACCGCGGCTAGCCTACGGCTACGGCCCGGGCAGCCTGCG CGAGCTGCGGGCGCGCGAGTTCAGCCGCCTGGCAGGAACTGTCTATCTTGACCATGCAGG TGCCACCTTGTTCTCCCAGAGCCAGCTCGAAAGCTTCACTAGTGATCTCATGGAAAACAC TTATGGTAATCCTCACAGCCAGAACATCAGCAGCAAGCTCACCCATGACACTGTGGAGCA GGTGCGCTACAGAATCCTGGCGCACTTCCACACCACCGCAGAAGACTACACTGTGATCTT CACTGCCGGGAGCACGGCTGCTCTCAAACTGGTGGCAGAGGCCTTTCCATGGGTGTCCCA GGGCCCAGAGAGCAGTGGGAGTCGCTTCTGTTACCTCACCGACAGCCACACCTCCGTAGT GGGTATGAGGAACGTGACCATGGCTATAAATGTCATATCCATCCCGGTCAGGCCAGAGGA CCTGTGGTCTGCAGAGGAACGTGGTGCTTCAGCCAGCAACCCAGACTGCCAGCTGCCGCA TCTCTTCTGCTACCCAGCTCAGAGTAACTTTTCTGGAGTCAGATACCCCCTGTCCTGGAT AGAAGAGGTCAAGTCTGGGCGGTTGCGCCCTGTGAGCACGCCTGGGAAGTGGTTTGTGCT GCTGGATGCAGCCTCCTACGTGAGCACCTCGCCTTTGGACCTGTCAGCTCACCAGGCCGA CTTTGTCCCCATCTCCTTCTATAAGATCTTCGGGTTTCCTACAGGCCTGGGCGCTCTGCT GGTCCATAATCGTGCGGCTCCTCTACTGAGGAAGACCTACTTTGGAGGAGGGACAGCCTC TGCGTACCTAGCAGGAGAAGACTTCTACATCCCGAGGCAGTCGGTAGCTCAGAGGTTTGA AGATGGCACCATCTCATTCCTTGATGTTATCGCGCTAAAACATGGATTTGACACCCTAGA GCGCCTCACAGGTGGAATGGAGAATATAAAGCAGCACACCTTCACCTTGGCTCAGTATAC CTACATGGCCCTGTCCTCTCTCCAGTACCCCAATGGAGCCCCTGTGGTGCGGATTTACAG CGATTCTGAGTTCAGCAGCCCTGAGGTTCAGGGCCCGATCATCAATTTTAATGTGCTGGA TGACAAAGGGAACATCATTGGTTACTCCCAGGTGGACAAAATGGCCAGTCTTTACAACAT CCACCTGCGAACTGGCTGCTTCTGTAACACTGGGGCCTGCCAGAGGCACCTGGGCATAAG CAACGAGATGGTCAGGAAGCATTTTCAGGCTGGTCATGTCTGTGGGGACAATATGGACCT CATAGATGGGCAGCCCACAGGATCTGTGAGGATTTCATTTGGATACATGTCGACGCTGGA TGATGTCCAGGCCTTTCTTAGGTTCATCATAGACACTCGCCTGCACTCATCAGGGGACTG GCCTGTCCCTCAGGCCCATGCTGACACCGGGGAGACTGGAGCCCCATCAGCAGACAGCCA GGCTGATGTTATACCTGCTGTCATGGGCAGACGTAGCCTCTCGCCTCAGGAAGATGCCCT CACAGGCTCCAGGGTTTGGAACAACTCGTCTACTGTGAATGCTGTGCCTGTGGCCCCACC TGTGTGTGATGTCGCCAGAACCCAGCCGACTCCTTCAGAGAAAGCTGCAGGAGTCCTGGA GGGGGCCCTTGGGCCACATGTTGTCACTAACCTTTATCTCTATCCAATCAAATCCTGTGC TGCATTTGAGGTGACCAGGTGGCCTGTAGGAAACCAAGGGCTGCTATATGACCGGAGCTG GATGGTTGTGAATCACAATGGTGTTTGCCTGAGTCAGAAGCAGGAACCCCGGCTCTGCCT GATCCAGCCCTTCATCGACTTGCGGCAAAGGATCATGGTCATCAAAGCCAAAGGGATGGA GCCTATAGAGGTGCCTCTTGAGGAAAATAGTGAACGGACTCAGATTCGCCAAAGCAGGGT CTGTGCTGACAGAGTAAGTACTTATGATTGTGGAGAAAAAATTTCAAGCTGGTTGTCAAC ATTTTTTGGCCGTCCTTGTCATTTGATCAAACAAAGTTCAAACTCTCAAAGGAATGCAAA GAAGAAACATGGAAAAGATCAACTTCCTGGTACAATGGCCACCCTTTCTCTGGTGAATGA GGCACAGTATCTGCTGATCAACACATCCAGTATTTTGGAACTTCACCGGCAACTAAACAC CAGTGATGAGAATGGAAAGGAGGAATTATTCTCACTGAAGGATCTCAGCTTGCGTTTTCG TGCCAATATTATTATCAATGGAAAAAGGGCTTTTGAAGAAGAGAAATGGGATGAGATTTC AATTGGCTCTTTGCGTTTCCAGGTTTTGGGGCCTTGTCACAGATGCCAGATGATTTGCAT CGACCAGCAAACTGGGCAACGAAACCAGCATGTTTTCCAAAAACTTTCTGAGAGTCGTGA AACAAAGGTGAACTTTGGCATGTACCTGATGCATGCATCATTGGATTTATCCTCCCCATG TTTCCTGTCTGTAGGATCTCAGGTGCTCCCTGTGTTGAAAGAGAATGTGGAAGGTCATGA TTTACCTGCATCTGAGAAACACCAGGATGTTACCTCCTAAAAAAAATTTTTAGCATACAT TAAAGTTTCTCTTTTAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_017947 unedited
NAAGTTAGGATTTTGTATACGACTTACTATAGGGCGGCCGCGATTCGGCACGAGGACTAG CCGGGGCCATGGCCGGCGCGGCGGCGGAGTCAGGGCGGGAGCTGTGGACCTTCGCGGGTT CCCGGGACCCGAGCGCACCGCGGCTAGCCTACGGCTACGGCCCGGGCAGCCTGCGCGAGC TGCGGGCGCGCGAGTTCAGCCGCCTGGCAGGAACTGTCTATCTTGACCATGCAGGTGCCA CCTTGTTCTCCCAGAGCCAGCTCGAAAGCTTCACTAGTGATCTCATGGAAAACACTTATG GTAATCCTCACAGCCAGAACATCAGCAGCAAGCTCACCCATGACACTGTGGAGCAGGTGC GCTACAGAATCCTGGCGCACTTCCACACCACCGCAGAAGACTACACTGTGATCTTCACTG CCGGGAGCACGGCTGCTCTCANACTGGTGGCAGAGGCCTTTCCATGGGTGTCCCAGGGCC CAGAGAGCAGTGGGAGTCGCTTCTGTTACCTCACCGACAGCCACACCTCCGTAGTGGGTA TGAGGAACGTGACCATGGCTATAAATGTCATATCCATCCCGGTCAGGCCAGAGGACCTGT GGTCTGCAGAGGAACGTGGTGCTTCANCCAGCAACCCAGACTGCCAGCTGCCGCATCTCT TCTGCTACCCAGCTCAGAGTAACTTTTCTGGAGTCAAATACCCCCTGTCCTGGATAGAAA AGGTCAAGTCTGGGCGGTTGCGCCCTGGGAACACGCCTGGGAAATGGTTTTGGCTGCTGG ATGCAACCTTCTACTTGAGCACCTCCCCTTGGGACTGGCAGCTCACCGGCCCACTTTGTC CCATCCTCTTCTATAAATCTTCGGGTTCCTACAGGCCGGGCGCCTTGTGGTCT |
Restriction Sites | Please inquire |
ACCN | NM_017947 |
Insert Size | 2733 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_017947.1, NP_060417.1 |
RefSeq Size | 2729 bp |
RefSeq ORF | 2667 bp |
Locus ID | 55034 |
UniProt ID | Q96EN8 |
Gene Summary | This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine. [provided by RefSeq, Apr 2017] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204120 | MOCOS (Myc-DDK-tagged)-Human molybdenum cofactor sulfurase (MOCOS) |
CNY 9,752.00 |
|
RC204120L1 | Lenti ORF clone of Human molybdenum cofactor sulfurase (MOCOS), Myc-DDK-tagged |
CNY 12,152.00 |
|
RC204120L2 | Lenti ORF clone of Human molybdenum cofactor sulfurase (MOCOS), mGFP tagged |
CNY 5,890.00 |
|
RC204120L3 | Lenti ORF clone of Human molybdenum cofactor sulfurase (MOCOS), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204120L4 | Lenti ORF clone of Human molybdenum cofactor sulfurase (MOCOS), mGFP tagged |
CNY 5,890.00 |
|
RG204120 | MOCOS (tGFP-tagged) - Human molybdenum cofactor sulfurase (MOCOS) |
CNY 11,352.00 |