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TTLL12 (NM_015140) Human Untagged Clone
CAT＃: SC122822
TTLL12 (untagged)-Human tubulin tyrosine ligase-like family, member 12 (TTLL12)
CNY 4,800.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | dJ526I14.2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_015140 edited
CTGGAGTCGGCGCGGGTGCTGGCGCCATGGAGGCCGAGCGGGGTCCCGAGCGCCGGCCTG CGGAGCGTAGCAGCCCGGGCCAGACGCCGGAGGAGGGCGCGCAGGCCTTGGCCGAGTTCG CGGCGCTGCACGGCCCGGCGCTGCGCGCTTCGGGGGTCCCCGAACGTTACTGGGGCCGCC TCCTGCACAAGCTGGAGCACGAGGTTTTCGACGCTGGGGAAGTGTTTGGGATCATGCAAG TGGAGGAGGTAGAAGAGGAGGAGGACGAGGCAGCCCGGGAGGTGCGGAAGCAGCAGCCCA ACCCGGGGAACGAGCTGTGCTACAAGGTCATCGTGACCAGGGAGAGCGGGCTCCAGGCAG CCCACCCCAACAGCATCTTCCTCATCGACCACGCCTGGACGTGCCGTGTGGAGCACGCGC GCCAGCAGCTGCAGCAGGTGCCCGGGCTGCTGCACCGCATGGCCAACCTGATGGGCATTG AGTTCCACGGTGAGCTGCCCAGTACAGAGGCTGTGGCCCTGGTGCTGGAGGAGATGTGGA AGTTCAACCAGACCTACCAGCTGGCCCATGGGACAGCTGAGGAGAAGATGCCGGTGTGGT ATATCATGGACGAGTTCGGTTCGCGGATCCAGCACGCGGACGTGCCCAGCTTCGCCACGG CACCCTTCTTCTACATGCCGCAGCAGGTGGCCTACACGCTGCTGTGGCCCCTGAGGGACC TGGACACTGGCGAGGAGGTGACCCGAGACTTTGCCTACGGAGAGACGGACCCCCTGATCC GGAAGTGCATGCTGCTGCCCTGGGCCCCCACCGACATGCTGGACCTCAGCTCTTGCACAC CCGAGCCGCCCGCCGAGCACTACCAGGCCATTCTGGAGGAAAACAAGGAGAAGCTGCCAC TTGACATCAACCCCGTGGTGCACCCCCACGGCCACATCTTCAAGGTCTACACGGACGTGC AGCAGGTGGCCAGCAGCCTCACCCACCCGCGCTTCACCCTCACCCAGAGTGAGGCGGACG CCGACATCCTCTTCAACTTCTCACACTTCAAGGACTACAGGAAACTCAGCCAGGAGAGGC CAGGCGTGCTGCTGAACCAGTTCCCCTGCGAGAACCTGCTGACTGTCAAGGACTGCCTGG CCTCCATCGCGCGCCGGGCAGGTGGCCCCGAGGGCCCACCCTGGCTGCCCCGAACCTTCA ACCTGCGCACTGAGCTGCCCCAGTTTGTCAGCTACTTCCAGCAGCGGGAAAGGTGGGGCG AGGACAACCACTGGATCTGCAAGCCCTGGAACCTGGCGCGCAGCCTGGACACCCACGTCA CCAAGAGCCTGCACAGCATCATCCGGCACCGAGAGAGCACCCCCAAGGTTGTGTCCAAGT ACATCGAAAGTCCCGTGTTGTTCCTTCGAGAAGACGTGGGAAAGGTCAAGTTCGACATCC GCTACATCGTGCTGCTGCGGTCAGTGAGGCCCCTACGGTTGTTCGTGTATGATGTGTTCT GGCTGCGGTTCTCCAACCGGGCCTTTGCACTCAACGACCTGGATGACTACGAGAAGCACT TCACGGTCATGAACTATGACCCGGATGTGGTGCTGAAGCAGGTGCACTGTGAAGAGTTCA TCCCCGAGTTTGAGAAGCAATACCCAGAATTTCCCTGGACGGACGTCCAGGCTGAGATCT TCCGGGCCTTCACGGAGCTGTTCCAGGTGGCCTGTGCCAAGCCACCACCCCTGGGCCTCT GCGACTACCCCTCATCCCGGGCCATGTATGCCGTCGACCTCATGCTGAAGTGGGACAACG GCCCAGATGGAAGGCGGGTGATGCAGCCGCAGATCCTGGAGGTGAACTTCAACCCCGACT GTGAGCGAGCCTGCAGGTACCACCCCACCTTCTTCAACGACGTCTTCAGCACCTTGTTTC TGGACCAGCCCGGTGGCTGCCACGTTACCTGCCTTGTCTAGGCACTCGCTGTCCCCAAAA CCTGTGCTTGGGGCAGGATTCCAACCTCAGTTCTCTGAGCTGCTTCTGCAAAGGCCCCCA TGTCCCTCCCCACACCGGCCCTGGGCATAGCCTCAGCCCCAGGCCTCTGTCCTGCCGAGC CATCCTCCCGGCGCCACACTCCGGGAGCACAGCATCCTCCTCTCACCTGTGGGTCAGAGC AGGACAGTGATGGTGTCCCCAGGGCTGAGCACCACCCCACGCCCTGCCCTCACCCCTCAC CACCATCTGTGCACTGATGAGTCTCCAGTTTAGCCAAGGGCTTCGTTCCTGGCATGGAGA ATTTGTTCCTGGCTGCTGTGTTTCCAGGGGGTGCTGGGGGAAGGGTTCCGTGGAGCGAGA CAAGGTGTCCTCGGGAGCAGGGTTCCACCGGGAAGCGTTTGGGAGCCCTGTATCACACGG GGCAGGCGGGTTTCTCTTCCGGGGTCTCTGCTCTTATGCATCAGGACGACCCCGGGACGG CTGTGGGGCCCCACACTGCACCCACAGGGCTCTATGCGACAGGGGCCCAGGAACAGCCTG AGGCCACCACCCAGCAAGCCCGCCTTATCACCCATTCCAGCTCACCCAGAACCTTCACCA GCAAACCTCCTGCTGAGGTCCTGGCAGGAGGCCACCGTCTTGTTACCGTTTCCTTTTCGT TTGCTGAGGGTCACAGACCCCAACAGGGAAATCAGTATCTGTCTTCCCAGTGGTTGCCCT GCTCGCCGGGCACTCCACGGGGTCCCGCCCTTGTGTGAGATGGGCCAGGATCCTTCGGCA AGGGGCGCCTGGGGCTGGGGCTGATTGTGGGCGGTGGAGCGCCAGACAGAAAAGGATTCC AATGAGAACTTCAGGTTAAAGTCAGATGCCACCTACCAGGGTCTACAGTCAAAATGTTGG CTTTTTCTTATTTTTTAATGTATGGGAGAAAAATGTAAAATTCCAGTTCTTTTCTAATTG TGTTTCTGAAATTAGGAGTCAGCTGCCAGCGTTTTTGTGTGGCTGCAGTGTGCCTGGGCC CAGCTCACGGGCAGTGGGTGGACCTAACTGCCCAGGCAGGCGAGAGCTACTTCCAGAGCC TTCCAGTGCATGGGAGGGCAGGGCTAGGTGTAGCGGTGTCTCCTCTTTGAAATTAAGAAC TATCTTTCTTGTAGCAAAGCTGCACCTGATGATGCTGCCTCTCCTCTCTGTGTTGTCTGG GCCCTTGTTTACAAGCACGCGTTACCCTTCCTGAGGGGAGCCATGCTCTAGCCCCTGGAG GGCCTGTTGCAGGGGCAGGGCGGGCCCGTCGCCTTTGGCAGCTCCTGGAGAGCTGTGGAC ATGCAGTCCCCCTCAGTTCGTGCTGCAATAAAGGCCATCTTCTCTTAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_015140 unedited
ATGTCATTTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCTGGAGTCG GCGCGGGTGCTGGCGCCATGGAGGCCGAGCGGGGTCCCGAGCGCCGGCCTGCGGAGCGTA GCATCCCGGGCCAGACGCCGGAGGAGGGCGCGCAGGCCTTGGCCGAGTTCGCGGCGCTGC ACGGCCCGGCGCTGCGCGCTTCGGGGGTCCCCGAACGTTACTGGGGCCGCCTCCTGCACA AGCTGGAGCACGAGGTTTTCGACGCTGGGGAAGTGTTTGGGATCATGCAAGTGGAGGAGG TAGAAGAGGAGGAGGACGAGGCAGCCCGGGAGGTGCGGAAGCAGCAGCCCAACCCGGGGA ACGAGCTGTGCTACAAGGTCATCGTGACCAGGGAGAGCGGGCTCCAGGCAGCCCACCCCA ACAGCATCTTCCTCATCGACCACGCCTGGACGTGCCGTGTGGAGCACGCGCGCCAGCAGC TGCAGCATGTGCCCGGGCTGCTGCACCGCATGGCCAACCTGATGGGCATTGAGTTCCACG GTGAGCTGCCCAGTACAGAGGCTGTGGCCCTGGTGCTGGAGGAGATGTGGAAGTTCAACC AGACCTACCAGCTGGCCCATGGGACAGCTGAGGAGAAGATGCCGGTGTGGTATATCATGG ACGAGTTCGGTTCGCGGATCCAGCACGCGGACGTGCCCAGCTTCGCCACGGCACCCTTCT TCTACATGCCGCATCATGTGGCCTACACGCTGCTGTGGCCCCTGAGGGACCTGGACACTG GCGAGGAGGTGACCCGAGACTTTGCCTACGGAGAGACCGACCCCCTGATCCGGAAGTGCA TGCTGGTGCCCTGGGCCCCCACCGAATGCTGGACCTCAGCTCTTGCCACCCGAGCG |
| Restriction Sites | Please inquire |
| ACCN | NM_015140 |
| Insert Size | 3394 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015140.2, NP_055955.1 |
| RefSeq Size | 3353 bp |
| RefSeq ORF | 1935 bp |
| Locus ID | 23170 |
| UniProt ID | Q14166 |
| Gene Summary | Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues (PubMed:20162578, PubMed:23251473). Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3) (PubMed:23251473). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability (PubMed:20162578, PubMed:23251473). During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE (PubMed:28011935).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200841 | TTLL12 (Myc-DDK-tagged)-Human tubulin tyrosine ligase-like family, member 12 (TTLL12) |
CNY 4,792.00 |
|
| RC200841L1 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 12 (TTLL12), Myc-DDK-tagged |
CNY 7,192.00 |
|
| RC200841L2 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 12 (TTLL12), mGFP tagged |
CNY 5,890.00 |
|
| RC200841L3 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 12 (TTLL12), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200841L4 | Lenti ORF clone of Human tubulin tyrosine ligase-like family, member 12 (TTLL12), mGFP tagged |
CNY 5,890.00 |
|
| RG200841 | TTLL12 (tGFP-tagged) - Human tubulin tyrosine ligase-like family, member 12 (TTLL12) |
CNY 6,392.00 |
