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SLC22A8 (NM_004254) Human Untagged Clone
CAT＃: SC122673
SLC22A8 (untagged)-Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1
CNY 6,464.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OAT3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004254 edited
AGCTTGTTAGAGCTGAGCTGCCCTACTACAGCAGCTGCCGGCCCCTAGGACAGAGCAGGG ACCTCAACTACACTGATCACCAGCCCCATCGGATCCAGACCCGGCCACCAGCTCTGGCTC GTCTTGCCCCAGTGCCATGACCTTCTCGGAGATCCTGGACCGTGTGGGAAGCATGGGCCA TTTCCAGTTCCTGCATGTAGCCATACTGGGCCTCCCGATCCTCAACATGGCCAACCACAA CCTGCTGCAGATCTTCACAGCCGCCACCCCTGTCCACCACTGTCGCCCGCCCCACAATGC CTCCACAGGGCCTTGGGTGCTCCCCATGGGCCCAAATGGGAAGCCTGAGAGGTGCCTCCG TTTTGTACATCCGCCCAATGCCAGCCTGCCCAATGACACCCAGAGGGCCATGGAGCCATG CCTGGATGGCTGGGTCTACAACAGCACCAAGGACTCCATTGTGACAGAGTGGGACTTGGT GTGCAACTCCAACAAACTGAAGGAGATGGCCCAGTCTATCTTCATGGCAGGTATACTGAT TGGAGGGCTCGTGCTTGGAGACCTGTCTGACAGGTTTGGCCGCAGGCCCATCCTGACCTG CAGCTACCTGCTGCTGGCAGCCAGCGGCTCCGGTGCAGCCTTCAGCCCCACCTTCCCCAT CTACATGGTCTTCCGCTTCCTGTGTGGCTTTGGCATCTCAGGCATTACCCTGAGCACCGT CATCTTGAATGTGGAATGGGTGCCTACCCGGATGCGGGCCATCATGTCGACAGCACTCGG GTACTGCTACACCTTTGGCCAGTTCATTCTGCCCGGCCTGGCCTACGCCATCCCCCAGTG GCGTTGGCTGCAGTTAACTGTGTCCATTCCCTTCTTCGTCTTCTTCCTATCATCCTGGTG GACACCAGAGTCCATACGCTGGTTGGTCTTGTCTGGAAAGTCCTCGAAGGCCCTGAAGAT ACTCCGGCGGGTGGCTGTCTTCAATGGCAAGAAGGAAGAGGGAGAAAGGCTCAGCTTGGA GGAGCTCAAACTCAACCTGCAGAAGGAGATCTCCTTGGCCAAGGCCAAGTACACCGCAAG TGACCTGTTCCGGATACCCATGCTGCGCCGCATGACCTTCTGTCTTTCCCTGGCCTGGTT TGCTACCGGTTTTGCCTACTATAGTTTGGCTATGGGTGTGGAAGAATTTGGAGTCAACCT CTACATCCTCCAGATCATCTTTGGTGGGGTCGATGTCCCAGCCAAGTTCATCACCATCCT CTCCTTAAGCTACCTGGGCCGGCATACCACTCAGGCCGCTGCCCTGCTCCTGGCAGGAGG GGCCATCTTGGCTCTCACCTTTGTGCCCTTGGACTTGCAGACCGTGAGGACAGTATTGGC TGTGTTTGGGAAGGGATGCCTATCCAGCTCCTTCAGCTGCCTCTTCCTCTACACAAGTGA ATTATACCCCACAGTCATCAGGCAAACAGGTATGGGCGTAAGTAACCTGTGGACCCGCGT GGGAAGCATGGTGTCCCCGCTGGTGAAAATCACGGGTGAGGTACAGCCCTTCATCCCCAA TATCATCTACGGGATCACCGCCCTCCTCGGGGGCAGTGCTGCCCTCTTCCTGCCTGAGAC CCTGAATCAGCCCTTGCCAGAGACTATCGAAGACCTGGAAAACTGGTCCCTGCGGGCAAA GAAGCCAAAGCAGGAGCCAGAGGTGGAAAAGGCCTCCCAGAGGATCCCTCTACAGCCTCA CGGACCAGGCCTGGGCTCCAGCTGAGGACAACGGAACCCCCTTTCCCTGCCCTCCAGAGA CTGATCCTAGCCAGGCACCTTAGGAGTATAGGGAGGCCCCATATAGGTCCATCCTCCTAG GATGAAGCCTTCTGAGAGCTTGGTGAAGGTGTCTCCATCACCACCACCAGAGCCTCCTGC CCAGCCCTGGCCAGTTCAAAGTTTCAGCCATCCCTGCCCTTGTTCTCCCTGCAACCCAGG CCCTGCCATTCTTCTGTCTAGCCCTTCCCCACTGGCCACCTTCCCCCACTGTCCCGGTCC TCTTCCCCTGAGGTCCCCTGATATCCCCTGGCTCAGTCCTAACAAGACTGAGTCTTAACA AGATGAGAAGTCCTCCCCTTCTTGCCTCCCACACTTTTCTTTGATGGGAGGTTTCAATAA ACAGCGATAAGAACTCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_004254 unedited
NNGGGAGTTCAGAATTTGTAATACGACTCACTATNAGGGCGGCCGCGNAATTCGCCATTA CGGCCGGGGAGCTTGTTAGAGCTGAGCTGCCCTACTACAGCAGCTGCCGGCCCCTAGGAC AGAGCAGGGACCTCAACTACACTGATCACCAGCCCCATCGGATCCAGACCCGGCCACCAG CTCTGGCTCGTCTTGCCCCAGTGCCATGACCTTCTCGGAGATCCTGGACCGTGTGGGAAG CATGGGCCATTTCCAGTTCCTGCATGTAGCCATACTGGGCCTCCCGATCCTCAACATGGC CAACCACAACCTGCTGCAGATCTTCACAGCCGCCACCCCTGTCCACCACTGTCGCCCGCC CCACAATGCCTCCACAGGGCCTTGGGTGCTCCCCATGGGCCCAAATGGGAAGCCTGAGAG GTGCCTCCGTTTTGTACATCCGCCCAATGCCAGCCTGCCCAATGACACCCAGAGGGCCAT GGAGCCATGCCTGGATGGCTGGGTCTACAACAGCACCAAGGACTCCATTGTGACAGAGTG GGACTTGGTGTGCAACTCCAACAAACTGAAGGAGATGGCCCAGTCTATCTTCATGGCAGG TATACTGATTGGAGGGCTCGTGCTTGGAGACCTGTCTGACAGGTTTGGCCGCAGGCCCAT CCTGACCTGCAGCTACCTGCTGCTGGCAGCCAGCGGCTCCGGTGCAGCCTTCAGCCCCAC CTTCCCCATCTACATGGTCTTCCGCTTCCTGTGTGGCTTTGGCATCTCAGGCATTACCCT GAGCACCGTCATCTTTGATGTGGAATGGGTGCCTACCCGGATGCGGGCCATCATGTCGAC AGCACTCGGGTACTGCTACACCTTTGGCCAGTTCATTCTGNCCGGNCTGGCCTACNGCAT TCCCCATGGCGTTGGC |
| Restriction Sites | Please inquire |
| ACCN | NM_004254 |
| Insert Size | 2200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004254.2, NP_004245.2 |
| RefSeq Size | 2207 bp |
| RefSeq ORF | 1629 bp |
| Locus ID | 9376 |
| UniProt ID | Q8TCC7 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, May 2010] Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same protein (isoform 1). |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux
,null,
Biochemical and Biophysical Research Communications
,PubMed ID 30343886
[SLC22A8]
|
|
Evaluation of the Effect of Cobicistat on the In Vitro Renal Transport and Cytotoxicity Potential of Tenofovir
,null,
Antimicrobial Agents and Chemotherapy
,PubMed ID 23896476
[SLC22A8]
|
|
Carrier-mediated transport of quercetin conjugates: involvement of organic anion transporters and organic anion transporting polypeptides.
,null,
Biochemical pharmacology
,PubMed ID 22634047
[SLC22A8]
|
|
Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6).
,null,
Biochemical pharmacology
,PubMed ID 21244849
[SLC22A8]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205056 | SLC22A8 (Myc-DDK-tagged)-Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1 |
CNY 6,056.00 |
|
| RC205056L1 | Lenti ORF clone of Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1, Myc-DDK-tagged |
CNY 8,456.00 |
|
| RC205056L2 | Lenti ORF clone of Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC205056L3 | Lenti ORF clone of Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1, Myc-DDK-tagged |
CNY 8,456.00 |
|
| RC205056L4 | Lenti ORF clone of Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1, mGFP tagged |
CNY 8,456.00 |
|
| RG205056 | SLC22A8 (tGFP-tagged) - Human solute carrier family 22 (organic anion transporter), member 8 (SLC22A8), transcript variant 1 |
CNY 7,656.00 |
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