CCN5 (NM_003881) Human Untagged Clone
CAT#: SC122664
WISP2 (untagged)-Human WNT1 inducible signaling pathway protein 2 (WISP2)
CNY 3,600.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CT58; CTGF-L; WISP2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_003881 edited
GTGTGTGTGTGTGTGTGTGTGCACGCGCGCGCGCGCGTGTGTACGCGTGCGTGTGCCTGT GTGTGCCTGGGAGTGACCTCACAGCTGCCGGAACATAAAGACTCACAGGTCCGCCTCCCA GGCTCAAAGCTGGCTCTGCAGGGGACATGAGAGGCACACCGAAGACCCACCTCCTGGCCT TCTCCCTCCTCTGCCTCCTCTCAAAGGTGCGTACCCAGCTGTGCCCGACACCATGTACCT GCCCCTGGCCACCTCCCCGATGCCCGCTGGGAGTACCCCTGGTGCTGGATGGCTGTGGCT GCTGCCGGGTATGTGCACGGCGGCTGGGGGAGCCCTGCGACCAACTCCACGTCTGCGACG CCAGCCAGGGCCTGGTCTGCCAGCCCGGGGCAGGACCCGGTGGCCGGGGGGCCCTGTGCC TCTTGGCAGAGGACGACAGCAGCTGTGAGGTGAACGGCCGCCTGTATCGGGAAGGGGAGA CCTTCCAGCCCCACTGCAGCATCCGCTGCCGCTGCGAGGACGGCGGCTTCACCTGCGTGC CGCTGTGCAGCGAGGATGTGCGGCTGCCCAGCTGGGACTGCCCCCACCCCAGGAGGGTCG AGGTCCTGGGCAAGTGCTGCCCTGAGTGGGTGTGCGGCCAAGGAGGGGGACTGGGGACCC AGCCCCTTCCAGCCCAAGGACCCCAGTTTTCTGGCCTTGTCTCTTCCCTGCCCCCTGGTG TCCCCTGCCCAGAATGGAGCACGGCCTGGGGACCCTGCTCGACCACCTGTGGGCTGGGCA TGGCCACCCGGGTGTCCAACCAGAACCGCTTCTGCCGACTGGAGACCCAGCGCCGCCTGT GCCTGTCCAGGCCCTGCCCACCCTCCAGGGGTCGCAGTCCACAAAACAGTGCCTTCTAGA GCCGGGCTGGGAATGGGGACACGGTGTCCACCATCCCCAGCTGGTGGCCCTGTGCCTGGG CCCTGGGCTGATGGAAGATGGTCCGTGCCCAGGCCCTTGGCTGCAGGCAACACTTTAGCT TGGGTCCACCATGCAGAACACCAATATTAACACGCTGCCTGGTCTGTCTGGATCCCGAGG TATGGCAGAGGTGCAAGACCTAGTCCCCTTTCCTCTAACTCACTGCCTAGGAGGCTGGCC AAGGTGTCCAGGGTCCTCTAGCCCACTCCCTGCCTACACACACAGCCTATATCAAACATG CACACGGGCGAGCTTTCTCTCCGACTTCCCCTGGGCAAGAGATGGGACAAGCAGTCCCTT AATATTGAGGCTGCAGCAGGTGCTGGGCTGGACTGGCCATTTTTCTGGGGGTAGGATGAA GAGAAGGCACACAGAGATTCTGGATCTCCTGCTGCCTTTTCTGGAGTTTGTAAAATTGTT CCTGAATACAAGCCTATGCGCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_003881 unedited
NGGGTGTTTGGGATATTTGTNATACGACTCACTATAGGCGGCCGCGNAATTCGGCCATTA CGGCCGGGGNGAGAAATTTATATGTATTGTGTGTGTGTGTGTGTGTGTGCACGCGCGCGC GCGCGTGTGTACGCGTGCGTGTGCCTGTGTGTGCCTGGGAGTGACCTCACAGCTGCCGGA ACATAAAGACTCACAGGTCCGCCTCCCAGGCTCAAAGCTGGCTCTGCAGGGGACATGAGA GGCACACCGAAGACCCACCTCCTGGCCTTCTCCCTCCTCTGCCTCCTCTCAAAGGTGCGT ACCCAGCTGTGCCCGACACCATGTACCTGCCCCTGGCCACCTCCCCGATGCCCGCTGGGA GTACCCCTGGTGCTGGATGGCTGTGGCTGCTGCCGGGTATGTGCACGGCGGCTGGGGGAG CCCTGCGACCAACTCCACGTCTGCGACGCCAGCCAGGGCCTGGTCTGCCAGCCCGGGGCA GGACCCGGTGGCCGGGGGGCCCTGTGCCTCTTGGCAGAGGACGACAGCAGCTGTGAGGTG AACGGCCGCCTGTATCGGGAAGGGGAGACCTTCCAGCCCCACTGCAGCATCCGCTGCCGC TGCGAGGACGGCGGCTTCACCTGCGTGCCGCTGTGCAGCGAGGATGTGCGGCTGCCCAGC TGGGACTGCCCCCACCCCAGGAGGGTCGAGGTCCTGGGCAAGTGCTGCCCTGAGTGGGTG TGCGGCCCAAGAGGGGGACTGGGGACCCAGCCCCTTCCAGCCCAAGGACCCCAGTTTTCN TGCCCTTGTCTCTCCCCTGCCCCCTGGTGTCCCCTGCCCAGAATGGAGCACGGGCCTGGG GCCCCTGCTCGACCACCTGGTGGGCTGGGCATGGGCACCCGGGTGTCCAACCAGAACCGC TTCTGCCGACTGAAGAC |
Restriction Sites | Please inquire |
ACCN | NM_003881 |
Insert Size | 1450 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_003881.2, NP_003872.1 |
RefSeq Size | 1433 bp |
RefSeq ORF | 753 bp |
Locus ID | 8839 |
UniProt ID | O76076 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
Gene Summary | This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) retains an intron in its 5' UTR compared to variant 1. Both variants 1 and 3 encode the same isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204636 | WISP2 (Myc-DDK-tagged)-Human WNT1 inducible signaling pathway protein 2 (WISP2) |
CNY 3,600.00 |
|
RC204636L1 | Lenti ORF clone of Human WNT1 inducible signaling pathway protein 2 (WISP2), Myc-DDK-tagged |
CNY 6,000.00 |
|
RC204636L2 | Lenti ORF clone of Human WNT1 inducible signaling pathway protein 2 (WISP2), mGFP tagged |
CNY 5,890.00 |
|
RC204636L3 | Lenti ORF clone of Human WNT1 inducible signaling pathway protein 2 (WISP2), Myc-DDK-tagged |
CNY 6,000.00 |
|
RC204636L4 | Lenti ORF clone of Human WNT1 inducible signaling pathway protein 2 (WISP2), mGFP tagged |
CNY 6,000.00 |
|
RG204636 | WISP2 (tGFP-tagged) - Human WNT1 inducible signaling pathway protein 2 (WISP2) |
CNY 5,200.00 |