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PAX8 (NM_003466) Human Untagged Clone
CAT＃: SC122658
PAX8 (untagged)-Human paired box 8 (PAX8), transcript variant PAX8A
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003466 edited
CTTCAGAAGGAGGAGAGACACCGGGCCCAGGGCACCCTCGCGGGCGGACCCAAGCAGTGA GGGCCTGCAGCCGGCCGGCCAGGGCAGCGGCAGGCGCGGCCCGGACCTACGGGAGGAAGC CCCGAGCCCTCGGCGGGCTGCGAGCGACTCCCCGGCGATGCCTCACAACTCCATCAGATC TGGCCATGGAGGGCTGAACCAGCTGGGAGGGGCCTTTGTGAATGGCAGACCTCTGCCGGA AGTGGTCCGCCAGCGCATCGTAGACCTGGCCCACCAGGGTGTAAGGCCCTGCGACATCTC TCGCCAGCTCCGCGTCAGCCATGGCTGCGTCAGCAAGATCCTTGGCAGGTACTACGAGAC TGGCAGCATCCGGCCTGGAGTGATAGGGGGCTCCAAGCCCAAGGTGGCCACCCCCAAGGT GGTGGAGAAGATTGGGGACTACAAACGCCAGAACCCTACCATGTTTGCCTGGGAGATCCG AGACCGGCTCCTGGCTGAGGGCGTCTGTGACAATGACACTGTGCCCAGTGTCAGCTCCAT TAATAGAATCATCCGGACCAAAGTGCAGCAACCATTCAACCTCCCTATGGACAGCTGCGT GGCCACCAAGTCCCTGAGTCCCGGACACACGCTGATCCCCAGCTCAGCTGTAACTCCCCC GGAGTCACCCCAGTCGGATTCCCTGGGCTCCACCTACTCCATCAATGGGCTCCTGGGCAT CGCTCAGCCTGGCAGCGACAAGAGGAAAATGGATGACAGTGATCAGGATAGCTGCCGACT AAGCATTGACTCACAGAGCAGCAGCAGCGGACCCCGAAAGCACCTTCGCACGGATGCCTT CAGCCAGCACCACCTCGAGCCGCTCGAGTGCCCATTTGAGCGGCAGCACTACCCAGAGGC CTATGCCTCCCCCAGCCACACCAAAGGCGAGCAGGGCCTCTACCCGCTGCCCTTGCTCAA CAGCACCCTGGACGACGGGAAGGCCACCCTGACCCCTTCCAACACGCCACTGGGGCGCAA CCTCTCGACTCACCAGACCTACCCCGTGGTGGCAGATCCTCACTCACCCTTCGCCATAAA GCAGGAAACCCCCGAGGTGTCCAGTTCTAGCTCCACCCCTTCCTCTTTATCTAGCTCCGC CTTTTTGGATCTGCAGCAAGTCGGCTCCGGGGTCCCGCCCTTCAATGCCTTTCCCCATGC TGCCTCCGTGTACGGGCAGTTCACGGGCCAGGCCCTCCTCTCAGGGCGAGAGATGGTGGG GCCCACGCTGCCCGGATACCCACCCCACATCCCCACCAGCGGACAGGGCAGCTATGCCTC CTCTGCCATCGCAGGCATGGTGGCAGGAAGTGAATACTCTGGCAATGCCTATGGCCACAC CCCCTACTCCTCCTACAGCGAGGCCTGGCGCTTCCCCAACTCCAGCTTGCTGAGTTCCCC ATATTATTACAGTTCCACATCAAGGCCGAGTGCACCGCCCACCACTGCCACGGCCTTTGA CCATCTGTAGTTGCCATGGGGACAGTGGGAGCGACTGAGCAACAGGAGGACTCAGCCTGG GACAGGCCCCAGAGAGTCACACAAAGGAATCTTTATTTATTACATGAAAAATAACCACAA GTCCAGCATTGCGGCACACTCCCTGTGTGGTTAATTTAATGAACCATGAAAGACAGGATG ACCTTGGACAAGGCCAAACTGTCCTCCAAGACTCCTTAATGAGGGGCAGGAGTCCCAGGG AAAGAGAACCATGCCATGCTGAAAAAGACAAAATTGAAGAAGAAATGTAGCCCCCAGCCG GTACCCACCAAAGGAGAGAAGAAGCAATAGCCGAGGAACTTGGGGGGATGGCGAATGGTT CCTGCCCGGGCCCAAGGGGTGCACAGGGCACCTCCATGGCTCCATTATTAACACAACTCT AGCAATTATGGACCATAAGCACTTCCCTCCAGCCCACAAGTCACAGCCTGGTGCCGAGGC TCTCCTCACCAGCCACCCAGGGAGTCACCTCCCTCAGCCTCCCGCCTGCCCCACACGGAG GCTCTGGCTGTCCTCTTTCTCCACTCCATTTGCTTGGCTCTTTCTACACCTCCCTCTTGG GCATGGGCTGAGGGCTGGAGCGAGTCCCTCAGAAATTCCACCAGGCTGTCAGCTGACCTC TTTTGCCTGCTGCTGTGAAGGTATAGCACCACCCCAGGTCCTCCTGCAGTGCGGCATCCC CTTGGCAGCTGCCGTCAGCCAGGCCAGCCCCAGGGAGCTTAAAACAGACATTCCACAGGG CCTGGGCCCCTGGGAGGTGAGGTGTGGTGTGCGGCTTCACCCAGGGCAGAACAAGGCAGA ATCGCAGGAAACCCGCTTCCCCTTCCTGACAGCTCCTGCCAAGCCAAATGTGCTTCCTGC AGCTCACGCCCACCAGCTACTGAAGGGACCCAAGGCACCCCCTGAAGCCAGCGATAGAGG GTCCCTCTCTGCTCCCCAGCAGCTCCTGCCCCCAAGGCCTGACTGTATATACTGTCAATG AAACTTTGTTTGGGTCAAGCTTCCTTCTTTCTACCCCCCAGACTTTGGCCTCTGAGTGAA ATGTCTCTCTTTGCCCTGTGGGGCTTCTCTCCTTGATGCTTCTTTCTTTTTTTAAAGACA ACCTGCCATTACCACATGACTCAATAAACCATTGCTCTTCAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_003466 unedited
NNAATAGCCGTACAGAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAG GCTTCAGAAGGAGAGAGACACCGGGCCCAGGGCACCCTCGCGGGCGGACCCAAGCAGTGA GGGCCTGCAGCCGGCCGGCCAGGGCAGCGGCAGGCGCGGCCCGGACCTACGGGAGGAAGC CCCGAGCCCTCGGCGGGCTGCGAGCGACTCCCCGGCGATGCCTCACAACTCCATCAGATC TGGCCATGGAGGGCTGAACCAGCTGGGAGGGGCCTTTGTGAATGGCAGACCTCTGCCGGA AGTGGTCCGCCAGCGCATCGTAGACCTGGCCCACCAGGGTGTAAGGCCCTGCGACATCTC TCGCCAGCTCCGCGTCAGCCATGGCTGCGTCAGCAAGATCCTTGGCAGGTACTACGAGAC TGGCAGCATCCGGCCTGGAGTGATAGGGGGCTCCAAGCCCAAGGTGGCCACCCCCAAGGT GGTGGAGAAGATTGGGGACTACAAACGCCAGAACCCTACCATGTTTGCCTGGGAGATCCG AGACCGGCTCCTGGCTGAGGGCGTCTGTGACAATGACACTGTGCCCAGTGTCAGATCCAT TAATAGAATCATCCGGACCAAAGTGCAGCAACCATTCAACCTCCCTATGGACAGCTGCGT GGCCACCAAGTCCCTGAGTCCCGGACACACGCTGATCCCCAGCTCAGCTGTAACTCCCCC CGGAGTCACCCCAGTTCGGATTCCCCTGGGCTCCACCTACTTCATCAATGGGCTCCTGGG CATCGCTCAACCTGGGCAGCGCAAGAGGAAAAGGTTGACAGTGGTCAGGATAACTGCCCA TAAACATTGGCTTCCAGAACAGCAGCAACGGACCCCGAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_003466 |
| Insert Size | 2698 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003466.2, NP_003457.1 |
| RefSeq Size | 2707 bp |
| RefSeq ORF | 1353 bp |
| Locus ID | 7849 |
| UniProt ID | Q06710 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Pathways in cancer, Thyroid cancer |
| Gene Summary | This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010] Transcript Variant: This variant (PAX8A) represents the longest transcript and encodes the longest isoform (PAX8A). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations
,Hart, MR;Anderson, DJ;Porter, CC;Neff, T;Levin, M;Horwitz, MS;,
PLoS Genet.
,PubMed ID 30216339
[PAX8]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200651 | PAX8 (Myc-DDK-tagged)-Human paired box 8 (PAX8), transcript variant PAX8A |
CNY 3,656.00 |
|
| RC200651L1 | Lenti ORF clone of Human paired box 8 (PAX8), transcript variant PAX8A, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC200651L2 | Lenti ORF clone of Human paired box 8 (PAX8), transcript variant PAX8A, mGFP tagged |
CNY 5,890.00 |
|
| RC200651L3 | Lenti ORF clone of Human paired box 8 (PAX8), transcript variant PAX8A, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC200651L4 | Lenti ORF clone of Human paired box 8 (PAX8), transcript variant PAX8A, mGFP tagged |
CNY 6,056.00 |
|
| RG200651 | PAX8 (tGFP-tagged) - Human paired box 8 (PAX8), transcript variant PAX8A |
CNY 5,256.00 |
