IL2 Receptor beta (IL2RB) (NM_000878) Human Untagged Clone
CAT#: SC122579
IL2RB (untagged)-Human interleukin 2 receptor, beta (IL2RB)
CNY 4,112.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CD122; IL15RB; IMD63; P70-75 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_000878 edited
GGGCCCTGGAGAGATGGCCACGGTCCCAGCACCGGGGAGGACTGGAGAGCGCGCGCTGCC ACCGCCCCATGTCTCAGCCAGGGCTTCCTTCCTCGGCTCCACCCTGTGGATGTAATGGCG GCCCCTGCTCTGTCCTGGCGTCTGCCCCTCCTCATCCTCCTCCTGCCCCTGGCTACCTCT TGGGCATCTGCAGCGGTGAATGGCACTTCCCAGTTCACATGCTTCTACAACTCGAGAGCC AACATCTCCTGTGTCTGGAGCCAAGATGGGGCTCTGCAGGACACTTCCTGCCAAGTCCAT GCCTGGCCGGACAGACGGCGGTGGAACCAAACCTGTGAGCTGCTCCCCGTGAGTCAAGCA TCCTGGGCCTGCAACCTGATCCTCGGAGCCCCAGATTCTCAGAAACTGACCACAGTTGAC ATCGTCACCCTGAGGGTGCTGTGCCGTGAGGGGGTGCGATGGAGGGTGATGGCCATCCAG GACTTCAAGCCCTTTGAGAACCTTCGCCTGATGGCCCCCATCTCCCTCCAAGTTGTCCAC GTGGAGACCCACAGATGCAACATAAGCTGGGAAATCTCCCAAGCCTCCCACTACTTTGAA AGACACCTGGAGTTCGAGGCCCGGACGCTGTCCCCAGGCCACACCTGGGAGGAGGCCCCC CTGCTGACTCTCAAGCAGAAGCAGGAATGGATCTGCCTGGAGACGCTCACCCCAGACACC CAGTATGAGTTTCAGGTGCGGGTCAAGCCTCTGCAAGGCGAGTTCACGACCTGGAGCCCC TGGAGCCAGCCCCTGGCCTTCAGGACAAAGCCTGCAGCCCTTGGGAAGGACACCATTCCG TGGCTCGGCCACCTCCTCGTGGGTCTCAGCGGGGCTTTTGGCTTCATCATCTTAGTGTAC TTGCTGATCAACTGCAGGAACACCGGGCCATGGCTGAAGAAGGTCCTGAAGTGTAACACC CCAGACCCCTCGAAGTTCTTTTCCCAGCTGAGCTCAGAGCATGGAGGAGACGTCCAGAAG TGGCTCTCTTCGCCCTTCCCCTCATCGTCCTTCAGCCCTGGCGGCCTGGCACCTGAGATC TCGCCACTAGAAGTGCTGGAGAGGGACAAGGTGACGCAGCTGCTCCTGCAGCAGGACAAG GTGCCTGAGCCCGCATCCTTAAGCAGCAACCACTCGCTGACCAGCTGCTTCACCAACCAG GGTTACTTCTTCTTCCACCTCCCGGATGCCTTGGAGATAGAGGCCTGCCAGGTGTACTTT ACTTACGACCCCTACTCAGAGGAAGACCCTGATGAGGGTGTGGCCGGGGCACCCACAGGG TCTTCCCCCCAACCCCTGCAGCCTCTGTCAGGGGAGGACGACGCCTACTGCACCTTCCCC TCCAGGGATGACCTGCTGCTCTTCTCCCCCAGTCTCCTCGGTGGCCCCAGCCCCCCAAGC ACTGCCCCTGGGGGCAGTGGGGCCGGTGAAGAGAGGATGCCCCCTTCTTTGCAAGAAAGA GTCCCCAGAGACTGGGACCCCCAGCCCCTGGGGCCTCCCACCCCAGGAGTCCCAGACCTG GTGGATTTTCAGCCACCCCCTGAGCTGGTGCTGCGAGAGGCTGGGGAGGAGGTCCCTGAC GCTGGCCCCAGGGAGGGAGTCAGTTTCCCCTGGTCCAGGCCTCCTGGGCAGGGGGAGTTC AGGGCCCTTAATGCTCGCCTGCCCCTGAACACTGATGCCTACTTGTCCCTCCAAGAACTC CAGGGTCAGGACCCAACTCACTTGGTGTAGACAGATGGCCAGGGTGGGAGGCAGGCAGCT GCCTGCTCTGCGCCGAGCCTCAGAAGGACCCTGTTGAGGGTCCTCAGTCCACTGCTGAGG ACACTCAGTGTCCAGTTGCAGCTGGACTTCTCCACCCGGATGGCCCCCACCCAGTCCTGC ACACTTGGTCCATCCATTTCCAAACCTCCACTGCTGCTCCCGGGTCCTGCTGCCCGAGCC AGGAACTGTGTGTGTTGCAGGGGGGCAGTAACTCCCCAACTCCCTCGTTAATCACAGGAT CCCACGAATTTAGGCTCAGAAGCATCGCTCCTCTCCAGCCCTGCAGCTATTCACCAATAT CAGTCCTCGCGGCTCTCCAGGGCTCCCTGCCCTGACCTCTTCCCTGGGTTTTCTGCCCCA GCCTCCTCCTTCCCTCCCCTCCCCGTCCACAGGGCAGCCTGAGCGTGCTTTCCAAAACCC AAATATGGCCACGCTCCCCCTCGGTTCAAAACCTTGCACAGGTCCCACTGCCCTCAGCCC CACTTCTCAGCCTGGTACTTGTACCTCCGGTGTCGTGTGGGGACATCCCCTTCTGCAATC CTCCCTACCGTCCTCCTGAGCCACTCAGAGCTCCCTCACACCCCCTCTGTTGCACATGCT ATTCCCTGGGGCTGCTGTGCGCTCCCCCTCATCTAGGTGACAAACTTCCCTGACTCTTCA AGTGCCGGTTTTGCTTCTCCTGGAGGGAAGCACTGCCTCCCTTAATCTGCCAGAAACTTC TAGCGTCAGTGCTGGAGGGAGAAGCTGTCAGGGACCCAGGGCGCCTGGAGAAAGAGGCCC TGTTACTATTCCTTTGGGATCTCTGAGGCCTCAGAGTGCTTGGCTGCTGTATCTTTAATG CTGGGGCCCAAGTAAGGGCACAGATCCCCCCACAAAGTGGATGCCTGCTGCATCTTCCCA CAGTGGCTTCACAGACCCACAAGAGAAGCTGATGGGGAGTAAACCCTGGAGTCCGAGGCC CAGGCAGCAGCCCCGCCTAGTGGTGGGCCCTGATGCTGCCAGGCCTGGGACCTCCCACTG CCCCCTCCACTGGAGGGGTCTCCTCTGCAGCTCAGGGACTGGCACACTGGCCTCCAGAAG GGCAGCTCCACAGGGCAGGGCCTCATTATTTTTCACTGCCCCAGACACAGTGCCCAACAC CCCGTCGTATACCCTGGATGAACGAATTAATTACCTGGCACCACCTCGTCTGGGCTCCCT GCGCCTGACATTCACACAGAGAGGCAGAGTCCCGTGCCCATTAGGTCTGGCATGCCCCCT CCTGCAAGGGGCTCAACCCCCTACCCCGACCCCTCCACGTATCTTTCCTAGGCAGATCAC GTTGCAATGGCTCAAACAACATTCCACCCCAGCAGGACAGTGACCCCAGTCCCAGCTAAC TCTGACCTGGGAGCCCTCAGGCACCTGCACTTACAGGCCTTGCTCACAGCTGATTGGGCA CCTGACCACACGCCCCCACGGGCTCTGACCAGCAGCCTATGAGGGGGTTTGGCACCAAGC TCTGTCCAATCAGGTAGGCTGGGCCTGAACTAGCCAATCAGATCAACTCTGTCTTGGGCG TTTGAACTCAGGGAGGGAGGCCCTTGGGAGCAGGTGCTTGTGGACAAGGCTCCACAAGCG TTGAGCCTTGGAAAGGTAGACAAGCGTTGAGCCACTAAGCAGAGGACCTTGGGTTCCCAA TACAAAAATACCTACTGCTGAGAGGGCTGCTGACCATTTGGTCAGGATTCCTGTTGCCTT TATATCCAAAATAAACTCCCCTTTCTTGAGGTTGTCTGAGTCTTGGGTCTATGCCTTGAA AAAAGCTGAATTATTGGACAGTCTCACCTCCTGCCATAGGGTCCTGAATGTTTCAGACCA CAAGGGGCTCCACACCTTTGCTGTGTGTTCTGGGGCAACCTACTAATCCTCTCTGCAAGT CGGTCTCCTTATCCCCCCAAATGGAAATTGTATTTGCCTTCTCCACTTTGGGAGGCTCCC ACTTCTTGGGAGGGTTACATTTTTTAAGTCTTAATCATTTGTGACATATGTATCTATACA TCCGTATCTTTTAATGATCCGTGTGTACCATCTTTGTGATTATTTTCTTAATATTTTTTC TTTAAGTCAGTTCATTTTCGTTGAAATACATTTATTTAAAGAAAAATCTTTGTTACTCTG TAAATGAAAAAACCCATTTTCGCTATAAATAAAAGGTAACTGTACAAAATAAAAAAAAAA AAAAAAAAAAAAAAA >OriGene 5' read for NM_000878 unedited
AAATTCCCAGGGATGGGCCCTGGTATATATGGCCACGGTACCCAGCACCGGGGAGGACTG GAGAGCGCGCGCTGCCACCGCCCCATGTCTCAGCCAGGGCTTCCTTCCTCGGCTCCACCC TGTGGATGTAATGGCGGCCCCTGCTCTGTCCTGGCGTCTGCCCCTCCTCATCCTCCTCCT GCCCCTGGCTACCTCTTGGGCATCTGCAGCGGTGAATGGCACTTCCCAGTTCACATGCTT CTACAACTCGAGAGCCAACATCTCCTGTGTCTGGAGCCAAGATGGGGCTCTGCAGGACAC TTCCTGCCAAGTCCATGCCTGGCCGGACAGACGGCGGTGGAACCAAACCTGTGAGCTGCT CCCCGTGAGTCAAGCATCCTGGGCCTGCAACCTGATCCTCGGAGCCCCAGATTCTCAGAA ACTGACCACAGTTGACATCGTCACCCTGAGGGTGCTGTGCCGTGAGGGGGTGCGATGGAG GGTGATGGCCATCCAGGACTTCAAGCCCTTTGAGAACCTTCGCCTGATGGCCCCCATCTC CCTCCAAGTTGTCCACGTGGAGACCCACAGATGCAACATAAGCTGGGAAATCTCCCAAGC CTCCCACTACTTTGAAAGACACCTGGAGTTCGAGGCCCGGACGCTGTTTCCCAGCCACAC CTGGGAGGAGGCCCCCCTGCTTGACTCTCAAGCAAAAGCATGAATTGGATCTGCCTGGAA ACGCTCACCCCCAACCCCCAGTATGACCCCCAGTGCCGGTCAAGCCTCTGTAAGGCAGCT CACGACTGGAGCCCTTGTATCAATCCCTGGCCTTCAGAAAAAACCTGGCGCCCTTGGGAA GGACACCATCCGGGGCTCTGCCCCCG |
Restriction Sites | Please inquire |
ACCN | NM_000878 |
Insert Size | 4035 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000878.2, NP_000869.1 |
RefSeq Size | 4045 bp |
RefSeq ORF | 1656 bp |
Locus ID | 3560 |
UniProt ID | P14784 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway |
Gene Summary | The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression. [provided by RefSeq, Sep 2016] Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC206591 | IL2RB (Myc-DDK-tagged)-Human interleukin 2 receptor, beta (IL2RB) |
CNY 4,104.00 |
|
RC206591L3 | Lenti ORF clone of Human interleukin 2 receptor, beta (IL2RB), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC206591L4 | Lenti ORF clone of Human interleukin 2 receptor, beta (IL2RB), mGFP tagged |
CNY 5,890.00 |
|
RG206591 | IL2RB (tGFP-tagged) - Human interleukin 2 receptor, beta (IL2RB) |
CNY 5,704.00 |
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