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RAG2 (NM_000536) Human Untagged Clone
CAT＃: SC122564
RAG2 (untagged)-Human recombination activating gene 2 (RAG2), transcript variant 1
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | RAG-2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000536 edited
ACTCTCTTTACAGTCAGCCTTCTGCTTGCCACAGTCATAGTGGGCAGTCAGTGAATCTTC CCCAAGTGCTGACAATTAATACCTGGTTTAGCGGCAAAGATTCAGAGAGGCGTGAGCAGC CCCTCTGGCCTTCAGACAAAAATCTACGTACCATCAGAAACTATGTCTCTGCAGATGGTA ACAGTCAGTAATAACATAGCCTTAATTCAGCCAGGCTTCTCACTGATGAATTTTGATGGA CAAGTTTTCTTCTTTGGACAAAAAGGCTGGCCCAAAAGATCCTGCCCCACTGGAGTTTTC CATCTGGATGTAAAGCATAACCATGTCAAACTGAAGCCTACAATTTTCTCTAAGGATTCC TGCTACCTCCCTCCTCTTCGCTACCCAGCCACTTGCACATTCAAAGGCAGCTTGGAGTCT GAAAAGCATCAATACATCATCCATGGAGGGAAAACACCAAACAATGAGGTTTCAGATAAG ATTTATGTCATGTCTATTGTTTGCAAGAACAACAAAAAGGTTACTTTTCGCTGCACAGAG AAAGACTTGGTAGGAGATGTTCCTGAAGCCAGATATGGTCATTCCATTAATGTGGTGTAC AGCCGAGGGAAAAGTATGGGTGCTCTCTTTGGAGGACGCTCATACATGCCTTCTACCCAC AGAACCACAGAAAAATGGAATAGTGTAGCTGACTGCCTGCCCTGTGTTTTCCTGGTGGAT TTTGAATTTGGGTGTGCTACATCATACATTCTTCCAGAACTTCAGGATGGGCTATCTTTT CATGTCTCTATTGCCAAAAATGACACCATCTATATTTTAGGAGGACATTCACTTGCCAAT AATATCCGGCCTGCCAACCTGTACAGAATAAGGGTTGATCTTCCCCTGGGTAGCCCAGCT GTGAATTGCACAGTCTTGCCAGGAGGAATCTCTGTCTCCAGTGCAATCCTGACTCAAACT AACAATGATGAATTTGTTATTGTTGGTGGCTATCAGCTTGAAAATCAAAAAAGAATGATC TGCAACATCATCTCTTTAGAGGACAACAAGATAGAAATTCGTGAGATGGAGACCCCAGAT TGGACCCCAGACATTAAGCACAGCAAGATATGGTTTGGAAGCAACACGGGAAATGGAACT GTTTTTCTTGGCATACCAGGAGACAATAAACAAGTTGTTTCAGAAGGATTCTATTTCTAT ATGTTGAAATGTGCTGAAGATGATACTAATGAAGAGCAGACAACATTCACAAACAGTCAA ACATCAACAGAAGATCCAGGGGATTCCACTCCCTTTGAAGACTCTGAAGAATTTTGTTTC AGTGCAGAAGCAAATAGTTTTGATGGTGATGATGAATTTGACACCTATAATGAAGATGAT GAAGAAGATGAGTCTGAGACAGGCTACTGGATTACATGCTGCCCTACTTGTGATGTGGAT ATCAACACTTGGGTACCATTCTATTCAACTGAGCTCAACAAACCCGCCATGATCTACTGC TCTCATGGGGATGGGCACTGGGTCCATGCTCAGTGCATGGATCTGGCAGAACGCACACTC ATCCATCTGTCAGCAGGAAGCAACAAGTATTACTGCAATGAGCATGTGGAGATAGCAAGA GCTCTACACACTCCCCAAAGAGTCCTACCCTTAAAAAAGCCTCCAATGAAATCCCTCCGT AAAAAAGGTTCTGGAAAAATCTTGACTCCTGCCAAGAAATCCTTTCTTAGAAGGTTGTTT GATTAGTTTTGCAAAAGCCTTTCAGATTCAGGTGTATGGAATTTTTGAATCTATTTTTAA AATCATAACATTGATTTTAAAAATACATTTTTGTTTATTTAAAATGCCTATGTTTTCTTT TAGTTACATGAATTAAGGGCCAGAAAAAAGTGTTTATAATGCAATGATAAATAAAGTCAT TCTAGACCCTATACATTTTGAAAATATTTTACCCAAATACTCAATTTACTAATTTATTCT TCACTGAGGATTTCTGATCTGATTTTTTATTCAACAAACCTTAAACACCCAGAAGCAGTA ATAATCATCGAGGTATGTTTATATTTATTATATGAGTCTTGGTAACAAATAACCTATAAA GTGTTTATGACAAATTTAGCCAATAAAGAAATTAACACCCAAAAGAATTAAATTGATTAT TTTGTGCAACATAACAATTCGGCAGTTGGCCAAAACTTAAAAGCAAGATCTACTACATCC CACATTAGTGTTCTTTATATACCTTCAAGCAACCCTTTGGATTATGCCCATGAACAAGTT AGTTTCTCATAGCTTTACAGATGTAGATATAAATATAAATATATGTATACATATAGATAG ATAATGTTCTCCACTGACACAAAAGAAGAAATAAATAATCTACATCAAAAAAAAAAAAAA AAAAAAAAAAAAAA >OriGene 5' read for NM_000536 unedited
GGTCAAAATTTGTATACGACTCATATGGGCGGCNCGCGAATCGGCCATTACGGCCGGGGA CTCTCTTTACAGTCAGCCTTCTGCTTGCCACAGTCATAGTGGGCAGTCAGTGAATCTTCC CCAAGTGCTGACAATTAATACCTGGTTTAGCGGCAAAGATTCAGAGAGGCGTGAGCAGCC CCTCTGGCCTTCAGACAAAAATCTACGTACCATCAGAAACTATGTCTCTGCAGATGGTAA CAGTCAGTAATAACATAGCCTTAATTCAGCCAGGCTTCTCACTGATGAATTTTGATGGAC AAGTTTTCTTCTTTGGACAAAAAGGCTGGCCCAAAAGATCCTGCCCCACTGGAGTTTTCC ATCTGGATGTAAAGCATAACCATGTCAAACTGAAGCCTACAATTTTCTCTAAGGATTCCT GCTACCTCCCTCCTCTTCGCTACCCAGCCACTTGCACATTCAAAGGCAGCTTGGAGTCTG AAAAGCATCAATACATCATCCATGGAGGGAAAACACCAAACAATGAGGTTTCAGATAAGA TTTATGTCATGTCTATTGTTTGCAAGAACAACAAAAAGGTTACTTTTCGCTGCACAGAGA AAGACTTGGTAGGAGATGTTCCTGAAGCCAGATATGGTCATTCCATTAATGTGGTGTACA GCCGAGGGAAAAGTATGGGTGCTCTCTTTGGAGGACGCTCATACATGCCTTCTACCCACA GAAACCACAGAAAATGGAATAGTGTAGCTGACTGCCTGCCCTGTGTTTTCCTGGTGGGAT TTGAATTTGGGTGTGCTACATCATACATTTCTTCAGAACTTCANGATGGGCTATCTTTTC ATGTCTCTATTGCCAANATGACACATCTATATTTTAGGAGGACATTCACTGCCAATAATA TCCGGCCTGCCAACCTGTACAGAATAAGGA |
| Restriction Sites | Please inquire |
| ACCN | NM_000536 |
| Insert Size | 2414 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000536.1, NP_000527.1 |
| RefSeq Size | 2414 bp |
| RefSeq ORF | 1584 bp |
| Locus ID | 5897 |
| UniProt ID | P55895 |
| Protein Families | Druggable Genome |
| Protein Pathways | Primary immunodeficiency |
| Gene Summary | This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the shortest transcript. Variants 1, 3 and 4 encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205065 | RAG2 (Myc-DDK-tagged)-Human recombination activating gene 2 (RAG2), transcript variant 1 |
CNY 3,928.00 |
|
| RC205065L1 | Lenti ORF clone of Human recombination activating gene 2 (RAG2), transcript variant 1, Myc-DDK-tagged |
CNY 6,328.00 |
|
| RC205065L2 | Lenti ORF clone of Human recombination activating gene 2 (RAG2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC205065L3 | Lenti ORF clone of Human recombination activating gene 2 (RAG2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205065L4 | Lenti ORF clone of Human recombination activating gene 2 (RAG2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG205065 | RAG2 (tGFP-tagged) - Human recombination activating gene 2 (RAG2), transcript variant 1 |
CNY 5,528.00 |
