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CLACP (COL25A1) (BC036669) Human Untagged Clone
CAT＃: SC122503
COL25A1 (untagged)-Human collagen, type XXV, alpha 1 (cDNA clone MGC:33431 IMAGE:5268875), complete cds
CNY 3,656.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLAC; CLACP; collagen, type XXV, alpha 1; collagen-like Alzheimer amyloid plaque component; collagenous Alzheimer amyloid plaque component; OTTHUMP00000196081; OTTHUMP00000196082 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for BC036669 edited
GAGGGGCCACTGTTGGGGCCCTCGAAAGAGGTGTCGGTCCTCTGGGAGTCGGAAGAGCTG TCTGGGATTATTTGAGGTGTAGAGGGTGGGAAGCGAAGCCGAGACGGCCGACCCCGCCAC GATGCTGCTGAAGAAGCACGCAGGGAAAGGAGGGGGCCGGGAGCCCAGATCCGAGGACCC GACCCCTGCCGAACAGCATTGTGCCCGGACCATGCCCCCGTGTGCCGTCCTGGCGGCCCT CCTGTCAGTGGTGGCCGTGGTGTCTTGCCTGTACCTGGGTGTGAAAACCAACGACCTCCA GGCGAGGATCGCCGCTCTCGAATCCGCCAAAGGGGCCCCTTCCATTCATCTGCTGCCTGA TACCCTGGATCACCTCAAGACTATGGTGCAAGAGAAAGTGGAGCGACTTCTGGCTCAGAA ATCCTATGAACATATGGCTAAAATAAGAATCGCAAGAGAAGCACCTTCAGAATGTAACTG CCCAGCAGGCCCTCCAGGGAAACGAGGTAAGAGAGGCCGAAGAGGAGAATCTGGTCCTCC TGGACAGCCTGGTCCTCAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGA TCAGGGACCTAGGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGG AATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAA TGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGA GAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAAT TAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGG GCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACC AGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAG AGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAAC TAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGG ACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAA CGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGG ACCTCCTGGACCTCAAGGACTACAAGGGACAAAGGGAGAGCAGGGATCTCCAGGAATCCC AGGGATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGGAG CCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTA TCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATG GACTTCCTGGACCAAAGGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAG ATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAG CTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTG GTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGCGAAA AGGGGGAAAAGGGAAAGAAAGGCAAAAAGGGGCCTAAAGGGGAGAAAGGAGAACAGGGTG CTCCTGGATTAGATGCACCCTGCCCGTTGGGGCCAGATGGCTTACCCATGCCTGGCTGTT GGCAAAAGTGATGAATCTAACCTTTCAAGCATGAAGTTGTGTATATAAGGGTCCATTTTT AATATTTATAGTTGAAAACTGAATTGCAGATTTTACAAGTCTGAGATATGTTTACATAGG GCTGCTTCTTCCTGTTGGCAGTAGTATACATGTCCATTTTTACTCCACTTACATCTGAAA TTGGGCAATTTGTGAAACCAGTGAGAATCCTGCAAAAAATATAGATCAGTATCTCCTTAT CTTATGTGAAGATACGTATTTATATGGACAAATCAGTGGTAGAGAATGATTGATTGTACT AGCTATTTTCCTTCTTTTGGCTTGCTAATTGCATGGACAAAAAGTGCCATGAAATAGTTT ACATGAAATGGTGACCAAATATGGACTCAAAGCTATGAAAATGTACTATACTGACTGATT TTAGAGCTGATTATCACATTCCCATTCACCTTTCATGTCGGCGTTGACTCATACCTACAC CACCCATTGAAACTAACTAAAAAAGCATGACTGTGTGCCAACCTGCTTGCTGTGCAACTT CAGATGCTAGCATGTTGATCAGGAGTCCTTTGATTACATCTGAACCTTTATTCCTTTTGT CATCTCAAGGGGGTTACACCATGGCTTATTGCCAAAAAGAGATAAGGTGGCGGAGAGCAC ACACACAATTTGTCTTGTATTTTGAGGGAGTTGCAGTCCTGACTGCAGATCTACAGCTTC CAGTATTGTGGGCTCATGTGGCCACTTTGGTTGAAATACGAAGGGGTTGAGCCTGTTGCT GCCACCAGTTTTCCTTGGGCTGCCCTTGGCAGTGAAGACATGGGAAGAGGACCGATTCAG CCTCCAGCACTGCCTCTCATGTGACCAAGTAGGAAAGAGGTTTACAAATGCAAACTTGCA GAACCACAGACTTTAAAAATATGTATAAATAAACTGAATTTCAGCAAGTGTTAATATAGG TGCTTTTAAAAATGACAGAGGCACAGCACTTCTTTTGGAATAGGAGATTCTTGGAATGGG AGATCCTGTCCCTGAGGGAAAAGGGATGTCCATCCCACCAAAACTTGGGTTGCTGAAGAA ATAACATGTTCTGAGAAGGGATCAGCCAAAATCGCCTCTCCCGATGATATAGGAGAGCTT ACTGGGACAATCTGTGCCAAAGTTGTTGTGAGAGCTTTCCTTCCTCCTACGATCCAACCA TGTCAAACATTTCCTACAAAGTTTGAGAAACAGACCAAATCTAAGATCTCAGAAAGCTGT GAAATATAGTTGCCATAAAGAAAATATTTTTCATCTACTTGCTCAAACTTTACCTAACCA TATTAGATGGAACATTTCTTTGCACAGTAAAGAGTTGGTAGCGTGTTTTGAAATGGCTTA TTCTAAGTGGAAGTGTTACATTGAAAGAAACATTATCAATGAGGAGTAGGCACCCTTTCA GCCCATTAGAGAATTCAATTTCTCTCCTGACTCAATGCCATCTTCTGGGAAGATTTCTAG TTTCATGCATAGGTGTCACCGCCAGAAGGGAAATTAACTCATCCTTGGCTTATAGTTAAG ATATAACCATAAGACAAGGAACCTAAAATCCTCATGATCTCATTTATGTTATGTAACCAA ATGACAGTCATACAAAATGGTATCTTCTTTTTTTTCTATTAAATTTTTAAGGTTGAAAGA TGTTTAAACTATTAGATCAGTCTAATTGGTAACATTTCTGGTAACATTCCACACCCCTAA GCCAGTTTAGCATTTTGAAAATAATGGAGGACATTTTCTAACAATTTCTTGTATGGCATG GTGTTAGGATAACGTATTGCTCAATGTCTGACACAATTTGTCTTAAATGGTTTGGAAAAA TGAACTGAAGTGGGTGGAACTACATTCTCTTCAGGAAAACAAACTACAGTGTCCAGTGGC TATATTTTTTTCCCTTCTATCTTTTTTTCTGCTCCTCTAGTAGAAAGAGGTGGATTGAAA TGGATCACTATTTAAAACTTGCACAGCTTCAGGAGACGATACCTCAACATCAAAAGAAAA ACACTTTATGTATAAAAAAATTTTTTGAAATACAGCCCTTCAAAGAATACTATTCTGTCC TGTGTGTATATTGAGTTTTTGCTCTATAACTGATTTGACAACATCAACTTATTTCATGAT TAAATGAGGTTGTAAACTTTCATTACATTTATTTCCTTGGGAAAAACAAAGGGATGGAAA TACTCCTCCTTGTTCAGTGGAATTGCTAGGTCTTAACCGTGATGGATAATCTTTAACTTT TGGTTACTACAATGTTTTCAAGCATCCATTTTGTCATATAGAGAATTCTTAAATAATTTC TAAGTGAATGAAAGAATTGTGTTTGTTGATATGTGTTGATAGATAATATACTTTCCTTAA AGATTTCTTTAATGTGTGTTATTGGATAGAGGGTTGAGAAAATATACATGAAAGACACAT TGGAAATAAGGCAAGGTCAGTTTCTATTTCTAATAAAACATTGAAGGATAGCAAATTGAT ATGTGTTTTAGATTTAAAATTGTTTTTCATTTATGTTGGTTGGTGCTAATGTATCTCTTT TCCTTTTTCTCTATGGACAATACAACTACTATGGATAATTTTATTTCCCTGTTTAATAGC ATTCCTAAATCATTAGTGTGTTATTTTATTTTTAAAGTTCATGAATTTGCTATAATTATG GTCCAATGACCAGGCTTTCTTAATGTAAAACAAAACAGTGTACCAATAGATGATGTGTGT TTACTCGGAAAAAAAAAAAAAAAA >OriGene 5' read for BC036669 unedited
NGGGACTGGGGTTTGTTATACCACTTTTATGGGCGGCCGCATAACTTCGTATAGCATACA TTATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGAGG GGCCACTGTTGGGGCCCTCGAAAGAGGTGTCGGTCCTCTGGGAGTCGGAAGAGCTGTCTG GGATTATTTGAGGTGTAGAGGGTGGGAAGCGAAGCCGAGACGGCCGACCCCGCCACGATG CTGCTGAAGAAGCACGCAGGGAAAGGAGGGGGCCGGGAGCCCAGATCCGAGGACCCGACC CCTGCCGAACAGCATTGTGCCCGGACCATGCCCCCGTGTGCCGTCCTGGCGGCCCTCCTG TCAGTGGTGGCCGTGGTGTCTTGCCTGTACCTGGGTGTGAAAACCAACGACCTCCAGGCG AGGATCGCCGCTCTCGAATCCGCCAAAGGGGCCCCTTCCATTCATCTGCTGCCTGATACC CTGGATCACCTCAAGACTATGGTGCAAGAGAAAGTGGAGCGACTTCTGGCTCAGAAATCC TATGAACATATGGCTAAAATAAGAATCGCAAGAGAAGCACCTTCAGAATGTAACTGCCCA GCAGGCCCTCCAGGGAAACGAGGTAAGAGAGGCCGAAGAGGAGAATCTGGTCCTCCTGGA CAGCCTGGTCCTCAGGGCCCTCCTGGTCCAAAGGCGATAAGGGAGAACAAGGTGATCAGG GACCTAGGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTC CAGGGATGAATGGGCAAAAGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGGAT ACCAGGACCTAAGGGAGAACCTGNAGAAACAAGTGAAAAGGGAGACGCTGGAGAGAACNG CCCCAAGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGAATTNAA |
| Restriction Sites | Please inquire |
| ACCN | BC036669 |
| Insert Size | 4649 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC036669.2, AAH36669.1 |
| RefSeq Size | 4644 bp |
| RefSeq ORF | 1488 bp |
| Locus ID | 84570 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
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