LASS3 (CERS3) (BC028703) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CerS3; LAG1 homolog, ceramide synthase 3; LAG1 longevity assurance homolog 3; MGC27091; OTTHUMP00000194816
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC028703 edited AGCGGCCTTGCAAAGTCCGTTAGGAGCGCTCCAGGGCTACAGTGCCCAGCGGTTAACAAG TTTGTAATTACTTTCGTGGGTTTCTACGTTGCAAATTGAGAAGAGGGTTGCTGGGTTGGG CCCCCCTCCTCTGGACGCTAACCCCACCCAGGTGGTGAAACAGGAAGCAACATCCCATCA GGAAGAACCTGAGGGTGCCATCCAGTAGCTTCGCCTCACGTCACTGACTGCCGTCAGTCA GAAATCTTGACTCGCAACTTTGGAGGGTGGGTCTCTGAAGGAATTTCAGGTCTTACACAG AGATGAGTTGTGCTGCTCTCTGAGGAGAACGAAGCTGGTTGGAACGTTGGAAGCTGCTCT CTGACTACACTTCACAAGCAAGGGGCACCTTTTGTGGACTGACATTTCAGAAAGGGATGT TGTGAAACAAAAGCTGACATTTATATATATATACATATATACAGTATTTGAGTTCCTCAG TAGAAAGCTATCATATATACTCAGAATGTTTTGGACGTTTAAAGAATGGTTCTGGTTGGA AAGATTCTGGCTTCCTCCAACAATAAAGTGGTCAGATCTTGAGGATCACGATGGACTCGT CTTTGTAAAACCTTCTCATTTATACGTGACAATTCCATATGCTTTTCTCTTGCTGATTAT CAGGCGTGTATTTGAAAAATTTGTTGCTTCACCTCTAGCAAAATCATTTGGCATTAAAGA GACAGTTCGAAAGGTTACACCAAATACTGTCTTAGAGAATTTTTTCAAACATTCCACAAG GCAACCATTGCAAACTGATATTTATGGACTGGCAAAGAAGTGTAACTTGACGGAGCGCCA GGTGGAAAGATGGTTTAGGAGTCGGCGGAATCAAGAGAGGCCTTCCAGGCTGAAGAAATT CCAGGAAGCTTGCTGGAGATTTGCATTTTACTTAATGATCACTGTTGCTGGAATTGCGTT TCTTTATGATAAACCTTGGCTATATGACTTATGGGAGGTTTGGAATGGCTATCCCAAACA GCCCCTGCTGCCATCGCAGTACTGGTACTACATTTTAGAAATGAGTTTTTATTGGTCTCT GTTATTTAGACTTGGCTTTGATGTCAAGAGAAAGGATTTTCTAGCTCATATCATCCACCA CCTGGCTGCTATTAGTCTGATGAGCTTCTCTTGGTGTGCTAATTATATTCGCAGTGGGAC CCTCGTGATGATTGTACACGATGTGGCTGACATTTGGCTGGAGTCTGCTAAGATGTTTTC TTATGCTGGATGGACGCAGACCTGTAACACCCTGTTTTTCATCTTCTCCACCATATTTTT CATCAGCCGCCTCATTGTTTTTCCTTTCTGGATTTTATATTGCACGCTGATCTTGCCTAT GTATCACCTCGAGCCTTTCTTTTCATACATCTTCCTCAACCTACAGCTCATGATCTTGCA GGTCCTTCACCGTTACTGGGGTTATTACATCTTGAAGATGCTCAACAGATGTATATTCAT GAAGAGCATCCAGGATGTGAGGAGTGATGACGAGGATTATGAAGAGGAAGAGGAAGAGGA AGAAGAAGAGGCTACCAAAGGCAAAGAGATGGATTGTTTAAAGAACGGCCTCGGGGCTGA GAGGCACCTCATTCCCAATGGCCAGCATGGCCATTAGCTGGAAGCCTACAGGACTCCCAT GGCACAGCATGCTGCAAGTACTGTTGGCAGCCTGGCTTCAGGCCCCACACAGACCCCACA TTCTGCCCTTCCCTCTTTCTCACCACCGCCTTCCCTCCCACCTAAGATGTGTTTACCAAA ATGTTGTTAACTTGTGTTAAAATGTTAAATATAAGCATGCCCATGGATTTTTACTGCAAA AAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC028703 unedited NNNGGGGGTATCAGAATATTTGTNAATACGNATTCACTATAGGGCCGGCGCGCGNGAATT CGNNCCCTTCCACGGNACCATGNACCATGNACCCTCCACACCAAAGCATCTGGGATGGCC CTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATC CCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAAC TACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCATAACTTCGTATAGCATAC ATTATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGCCT TGCAAAGTCCGTTAGGAGCGCTCCAGGGCTACAGTGCCCAGCGGTTAACAAGTTTGTAAT TACTTTCGTGGGTTTCTACGTTGCAAATTGAGAAGAGGGTTGCTGGGTTGGGCCCCCCTC CTCTGGACGCTAACCCCACCCAGGTGGTGAAACAGGAAGCAACATCCCATCAGGAAGAAC CTGAGGGTGCCATCCAGTAGCTTCGCCTCACGTCACTGACTGCCGTCAGTCAGAAATCTT GACTCGCAACTTTGGAGGGTGGGTCTCTGAAGGAATTTCAGGTCTTACACAGAGATGAGT TGTGCTGCTCTCTGAGGAGAACGAAGCTGGTTGGAACGTTGGAAGCTGCTCTCTGACTAC ACTTCACAAGCAAGGGGCACCTTTTGTGGACTGACATTTCAGAAAGGGATGTTGTGAAAC AAAAGCTGACATTTATATATATATACATATATACAGTATTTGAGTTCCTCAGTAGAAAGC TATCATATATACTCAGAATGGTTTGGACGTTTAAAGAATGTGTCTGGTTTGGAAAGATTC TGCCTTCCTTCAACAATAAATTGGCCGAATCTTGG
Restriction Sites	Please inquire
ACCN	BC028703
Insert Size	1872 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC028703.1, AAH28703.1
RefSeq Size	1872 bp
RefSeq ORF	1149 bp
Locus ID	204219
Protein Families	Transcription Factors, Transmembrane
Gene Summary	This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.