ATF6 beta (ATF6B) (BC008394) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	activating transcription factor 6 beta; cAMP responsive element binding protein-like 1; Creb-related protein; CREB-RP; CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta; FLJ10066; G13; OTTHUMP00000029433; protein G13
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008394 edited GGGTGGGGGGGAAAGATGGCGGAGCTGATGCTGCTCAGCGAGATTGCTGACCCGACGCGT TTCTTCACCGACAACCTGCTTAGCCCGGAGGACTGGGGTCTGCAGAACAGCACCTTGTAT TCTGGCCTAGATGAAGTGGCCGAGGAGCAGACGCAGCTCTTCCGTTGCCCGGAGCAGGAT GTCCCGTTTGACGGCAGCTCCCTGGACGTGGGGATGGATGTCAGCCCCTCTGAGCCCCCA TGGGAACTCCTGCCGATCTTCCCAGATCTTCAGGTGAAGTCTGAGCCATCTTCCCCCTGC TCTTCCTCCTCCCTCAGCTCCGAGTCATCGCGTCTCTCCACAGAGCCATCCAGCGAGGCT CTTGGGGTAGGGGAGGTGCTCCATGTGAAGACAGAGTCCTTGGCACCCCCACTGTGTCTC CTGGGAGATGACCCAACATCCTCATTTGAAACCGTCCAGATCAACGTTATCCCCACCTCT GATGATTCCTCAGATGTCCAGACCAAGATAGAACCTGTCTCTCCATGTTCTTCCGTCAAC TCTGAGGCCTCCCTGCTCTCGGCCGACTCCTCCAGCCAGGCTTTTATAGGAGAGGAGGTC CTGGAAGTGAAGACAGAGTCCCTGTCCCCTTCAGGATGCCTCCTGTGGGATGTCCCAGCC CCCTCACTTGGAGCTGTCCAGATCAGCATGGGCCCATCCCTTGATGGCTCCTCAGGCAAA GCCCTGCCCACCCGGAAGCCGCCACTGCAGCCCAAACCTGTAGTGCTAACCACTGTCCCA ATGCCATCCAGAGCTGTGTCTCCCAGCACCACAGTCCTTCTGCAGTCCCTCGTCCAGCCA CCCCCAGGTACTGAAGAAGGAGAAAAGGGCCGGGCATGGTGGCTCACGCCGGTAATCCCA GCACTTTGGGAGGCTGAGGCGGGCGAATCACCTGAGGTCAGAAGTTTAAGACCAGCCTGG CCAACGTGGTGAAACCTTGTCTCTACTAAAAATACAAAAATTAGCGTGGAGTGGTGGCAG GCGCCTGTAATCCCAGCTCCTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGG CGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAAGCGAGA CTTTGTCCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008394 unedited AAGTTTTCATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCCATTACGGCCGGGG GGGTGGGGGGGAAAGAGGCGGAGCTGATGCTGCTCAGCGAGATTGCTGACCCGACGCGTT TCTTCACCGACAACCTGCTTAGCCCGGAGGACTGGGGTCTGCAGAACAGCACCTTGTATT CTGGCCTAGATGAAGTGGCCGAGGAGCAGACGCAGCTCTTCCGTTGCCCGGAGCAAGATG TCCCGTTTGACGGCAGCTCCCTGGACGTGGGGATGGATGTCAGCCCCTCTGAGCCCCCAT GGGAACTCCTGCCGATCTTCCCAGATCTTCAAGTGAAGTCTGAGCCATCTTCCCCCTGCT CTTCCTCCTCCCTCAGCTCCGAGTCATCGCGTCTCTCCACAGAGCCATCCAGCGAGGCTC TTGGGGTAGGGGAGGTGCTCCATGTGAAGACAGAGTCCTTGGCACCCCCACTGTGTCTCC TGGGAGATGACCCAACATCCTCATTTGAAACCGTCCAGATCAACGTTATCCCCACCTCTG ATGATTCCTCAGATGTCCAGACCAAGATAGAACCTGTCTCTCCATGTTCTTCCGTCAACT CTGAAGCCTCCCTGCTCTCGGCCGACTCCTCCAGCCAGGCTTTTATAGGAGAGGANGTCC TGGNAGTGAAGACAGAGTCCCTGTCCCCTTCNAGATGCCTCCTGTGGGATGTCCCAGCCC CCTCACTTGGAGCTGTCCAGATCAGCATGGGCCCATCCCTTGATGGCTCCTCCAGCAAAG CCCTGCCCCACCGGAAGCCGCCACTGCAGCCCNAAACTGTAGTGCTAACCACTGTCCCAA TGCCATNCAGAGCTGTGTCTNCCAGCACACAGTCCTTCTGCAGTCCNNTCGTCAGCCACC CCCAGTACTGAAGAA
Restriction Sites	Please inquire
ACCN	BC008394
Insert Size	1180 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC008394.1, AAH08394.1
RefSeq Size	1180 bp
Locus ID	1388
Protein Families	Transcription Factors
Gene Summary	The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

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