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BMX (NM_203281) Human Untagged Clone
CAT＃: SC120834
BMX (untagged)-Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1
CNY 7,424.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ETK; PSCTK2; PSCTK3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120834 sequence for NM_203281 edited (data generated by NextGen Sequencing)
ATGGATACAAAATCTATTCTAGAAGAACTTCTTCTCAAAAGATCACAGCAAAAGAAGAAA ATGTCACCAAATAATTACAAAGAACGGCTTTTTGTTTTGACCAAAACAAACCTTTCCTAC TATGAATATGACAAAATGAAAAGGGGCAGCAGAAAAGGATCCATTGAAATTAAGAAAATC AGATGTGTGGAGAAAGTAAATCTCGAGGAGCAGACGCCTGTAGAGAGACAGTACCCATTT CAGATTGTCTATAAAGATGGGCTTCTCTATGTCTATGCATCAAATGAAGAGAGCCGAAGT CAGTGGTTGAAAGCATTACAAAAAGAGATAAGGGGTAACCCCCACCTGCTGGTCAAGTAC CATAGTGGGTTCTTCGTGGACGGGAAGTTCCTGTGTTGCCAGCAGAGCTGTAAAGCAGCC CCAGGATGTACCCTCTGGGAAGCATATGCTAATCTGCATACTGCAGTCAATGAAGAGAAA CACAGAGTTCCCACCTTCCCAGACAGAGTGCTGAAGATACCTCGGGCAGTTCCTGTTCTC AAAATGGATGCACCATCTTCAAGTACCACTCTAGCCCAATATGACAACGAATCAAAGAAA AACTATGGCTCCCAGCCACCATCTTCAAGTACCAGTCTAGCGCAATATGACAGCAACTCA AAGAAAATCTATGGCTCCCAGCCAAACTTCAACATGCAGTATATTCCAAGGGAAGACTTC CCTGACTGGTGGCAAGTAAGAAAACTGAAAAGNAGCAGCAGCAGTGAAGATGTTGCAAGC AGTAACCAAAAAGAAAGAAATGTGAATCACACCACCTCAAAGATTTCATGGGAATTCCCT GAGTCAAGTTCATCTGAAGAAGAGGAAAACCTGGATGATTATGACTGGTTTGCTGGTAAC ATCTCCAGATCACAATCTGAACAGTTACTCAGACAAAAGGGAAAAGAAGGAGCATTTATG GTTAGAAATTCGAGCCAAGTGGGAATGTACACAGTGTCCTTATTTAGTAAGGCTGTGAAT GATAAAAAAGGAACTGTCAAACATTACCACGTGCATACAAATGCTGAGAACAAATTATAC CTGGCAGAAAACTACTGTTTTGATTCCATTCCAAAGCTTATTCATTATCATCAACACAAT TCAGCAGGCATGATCACACGGCTCCGCCACCCTGTGTCAACAAAGGCCAACAAGGTCCCC GACTCTGTGTCCCTGGGAAATGGAATCTGGGAACTGAAAAGAGAAGAGATTACCTTGTTG AAGGAGCTGGGAAGTGGCCAGTTTGGAGTGGTCCAGCTGGGCAAGTGGAAGGGGCAGTAT GATGTTGCTGTTAAGATGATCAAGGAGGGCTCCATGTCAGAAGATGAATTCTTTCAGGAG GCCCAGACTATGATGAAACTCAGCCATCCCAAGCTGGTTAAATTCTATGGAGTGTGTTCA AAGGAATACCCCATATACATAGTGACTGAATATATAAGCAATGGCTGCTTGCTGAATTAC CTGAGGAGTCACGGAAAAGGACTTGAACCTTCCCAGCTCTTAGAAATGTGCTACGATGTC TGTGAAGGCATGGCCTTCTTGGAGAGTCACCAATTCATACACCGGGACTTGGCTGCTCGT AACTGCTTGGTGGACAGAGATCTCTGTGTGAAAGTATCTGACTTTGGAATGACAAGGTAT GTTCTTGATGACCAGTATGTCAGTTCAGTCGGAACAAAGTTTCCAGTCAAGTGGTCAGCT CCAGAGGTGTTTCATTACTTCAAATACAGCAGCAAGTCAGACGTATGGGCATTTGGGATC CTGATGTGGGAGGTGTTCAGCCTGGGGAAGCAGCCCTATGACTTGTATGACAACTCCCAG GTGGTTCTGAAGGTCTCCCAGGGCCACAGGCTTTACCGGCCCCACCTGGCATCGGACACC ATCTACCAGATCATGTACAGCTGCTGGCACGAGCTTCCAGAAAAGCGTCCCACATTTCAG CAACTCCTGTCTTCCATTGAACCACTTCGGGAAAAAGACAAGCATTGA Clone variation with respect to NM_203281.2 753 t=>n >OriGene 5' read for NM_203281 unedited
NGGTTAGCATTTGTATACGACTTCTATAGGCGGCNCGCGAATTCGCACGAGTGTGAAACA ATTTGCTTCTGGAAACAGGACAGCCGGGGCCGTGTTCCTGCAACAGCAGACCAAGCACCG CGGCGGACCCAGGCAAGCACGGAACAAGCTGAGACGGATGATAATATGGATACAAAATCT ATTCTAGAAGAACTTCTTCTCAAAAGATCACAGCAAAAGAAGAAAATGTCACCAAATAAT TACAAAGAACGGCTTTTTGTTTTGACCAAAACAAACCTTTCCTACTATGAATATGACAAA ATGAAAAGGGGCAGCAGAAAAGGATCCATTGAAATTAAGAAAATCAGATGTGTGGAGAAA GTAAATCTCGAGGAGCAGACGCCTGTAGAGAGACAGTACCCATTTCAGATTGTCTATAAA GATGGGCTTCTCTATGTCTATGCATCAAATGAAGAGAGCCGAAGTCAGTGGTTGAAAGCA TTACAAAAAGAGATAAGGGGTAACCCCCACCTGCTGGTCAAGTACCATAGTGGGTTCTTC GTGGACGGGAAGTTCCTGTGTTGCCAGCAGAGCTGTAAAGCAGCCCCAGGATGTACCCTC TGGGAAGCATATGCTAATCTGCATACTGCAGTCAATGAAGAGAAACACAGAGTTCCCACC TTCCCAGACAGAGTGCTGAAGATACCTCGGGCAGTTCCTGTTCTCAAAATGGATGCACCA TCTTCAAGTACCACTCTAGCCCNATATGACAACGAATCANAGAAAAACTATGGCTCCCAG CCACCATCTTCAAGTACCAGTCTAGCGCAATATGACAGNCACTCANAGAAATCTATGGGC TCCACCAAACTTCACATGCAGTATATTCCAGGGGAGACTTCCTGACTGGTGGGCAGTAGA AACTGANAGCAGCACAGTGAAGATGTGCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_203281 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_203281.1, NP_975010.1 |
| RefSeq Size | 2540 bp |
| RefSeq ORF | 2028 bp |
| Locus ID | 660 |
| UniProt ID | P51813 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 2 encode the same isoform. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Tyrosine Kinase BMX Is an Essential Mediator of Inflammatory Arthritis in a Kinase-Independent Manner
,Marie Gottar-Guillier, Francis Dodeller, Dieter Huesken, Vadim Iourgenko, Craig Mickanin, Mark Labow, Samuel Gaveriaux, Bernd Kinzel, Matthias Mueller, Kari Alitalo, Amanda Littlewood-Evans, and Bruno Cenni,
J. Immunol., May 2011; 186: 6014 - 6023
[BMX]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202002 | BMX (Myc-DDK-tagged)-Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1 |
CNY 7,416.00 |
|
| RC202002L1 | Lenti ORF clone of Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1, Myc-DDK-tagged |
CNY 9,816.00 |
|
| RC202002L2 | Lenti ORF clone of Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1, mGFP tagged |
CNY 9,816.00 |
|
| RC202002L3 | Lenti ORF clone of Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202002L4 | Lenti ORF clone of Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG202002 | BMX (tGFP-tagged) - Human BMX non-receptor tyrosine kinase (BMX), transcript variant 1 |
CNY 4,370.00 |
