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Slingshot homolog 1 (SSH1) (NM_018984) Human Untagged Clone
CAT＃: SC120511
SSH1 (untagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 1
CNY 7,312.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SSH1L |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_018984 edited
GAGGGCCCGGCCCGGGCGGCGGTGGCGGTGGCGGCTCTAGCTCGAGACGTCTGTGGCGCC CTCGCACCGCGCCGCAGCCATGGCCCTGGTGACCCTGCAGCGCTCGCCCACGCCCAGCGC CGCCTCCTCCTCGGCCAGCAACAGCGAGTTGGAGGCTGGCAGCGAAGAAGATCGAAAATT AAACCTCAGCTTAAGTGAGAGCTTTTTCATGGTGAAAGGCGCAGCCCTCTTCTTACAACA GGGAAGCAGCCCTCAAGGCCAGCGGAGTCTTCAGCACCCCCACAAGCATGCAGGTGATCT GCCTCAACATCTTCAGGTGATGATCAACCTTCTGCGTTGCGAAGACAGAATCAAGCTGGC AGTGCGCCTGGAGAGCGCCTGGGCGGACCGGGTCCGGTACATGGTGGTGGTGTACAGCAG CGGGCGCCAGGACACCGAGGAGAATATCTTGCTGGGAGTGGACTTTTCCAGTAAGGAAAG TAAAAGCTGCACCATTGGGATGGTTCTCCGACTGTGGAGCGACACGAAAATCCACCTTGA TGGAGATGGTGGGTTCAGCGTGAGCACAGCAGGAAGGATGCACATATTTAAGCCTGTGTC TGTCCAGGCCATGTGGTCTGCCCTGCAGGTGCTTCACAAGGCCTGCGAAGTGGCCCGGAG GCACAACTACTTCCCCGGGGGTGTAGCTCTCATCTGGGCTACCTACTATGAGAGCTGCAT CAGCTCCGAGCAGAGCTGCATCAACGAGTGGAACGCCATGCAGGACCTGGAGTCTACGCG GCCCGACTCCCCCGCGCTATTTGTGGACAAGCCCACTGAAGGGGAAAGGACCGAGCGCCT CATCAAAGCCAAGCTCCGAAGCATCATGATGAGCCAGGATCTAGAAAATGTGACTTCCAA AGAGATTCGTAATGAATTAGAGAAACAGATGAATTGTAACTTGAAGGAACTCAAGGAATT TATAGACAATGAGATGCTACTTATCTTGGGACAGATGGACAAGCCCTCCCTTATCTTCGA TCATCTTTATCTCGGTTGATTACATTTTAAATGTTACCAGAGAAATCGATAATTTTTTTC CTGGCTTATTTGCATATCATAACATCCGAGTCTACGATGAAGAGACCACAGACCTCCTCG CCCACTGGAATGAAGCGTATCATTTTATAAACAAAGCGAAGAGGAACCATTCCAAGTGCC TGGTGCATTGCAAAATGGGCGTGAGTCGCTCGGCCTCCACAGTCATAGCCTATGCAATGA AGGAATTCGGCTGGCCTCTGGAAAAAGCATATAACTATGTAAAGCAGAAGCGCAGCATCA CGCGCCCCAACGCGGGCTTTATGAGGCAGCTGTCTGAGTATGAAGGCATCTTGGATGCAA GCAAACAGCGGCACAACAAGCTGTGGCGTCAGCAGACAGACAGCAGCCTCCAGCAGCCTG TGGATGACCCTGCAGGACCTGGCGACTTCTTGCCAGAGACCCCAGATGGCACCCCGGAAA GCCAGCTGCCCTTCTTGGATGATGCCGCCCAGCCCGGCTTAGGGCCCCCCCTCCCCTGCT GTTTCCGGCGACTCTCAGACCCCCTTCTGCCTTCCCCTGAGGATGAAACTGGCAGCTTGG TCCACCTGGAGGATCCGGAGAGGGAGGCTCTGTTGGAGGAAGCTGCTCCACCTGCAGAGG TGCACAGGCCGGCCAGACAGCCCCAGCAAGGTTCCGGACTCTGTGAGAAGGATGTGAAGA AGAAACTAGAGTTTGGGAGTCCCAAAGGTCGGAGCGGCTCCTTGCTGCAGGTGGAGGAGA CGGAAAGGGAGGAGGGCCTGGGAGCAGGGAGGTGGGGGCAGCTTCCAACCCAGCTCGATC AAAACCTGCTCAACTCGGAGAACCTAAACAACAACAGCAAGAGGAGCTGTCCCAACGGCA TGGAGGATGATGCTATATTTGGGATCCTTAACAAAGTGAAGCCTTCCTATAAATCCTGTG CCGACTGCATGTACCCTACAGCCAGCGGGGCTCCTGAGGCCTCCAGGGAGCGATGTGAGG ACCCCAATGCTCCCGCCATCTGCACCCAGCCAGCCTTCCTACCCCACATCACGTCCTCCC CTGTGGCCCACTTGGCCAGCAGGTCCCGTGTTCCGGAGAAGCCAGCCTCTGGCCCAACCG AACCTCCCCCGTTCCTACCACCAGCAGGCTCCAGGAGGGCAGACACCAGTGGCCCTGGGG CTGGAGCTGCCCTAGAGCCACCAGCCAGCCTTTTGGAACCTTCCAGAGAGACCCCAAAAG TCCTGCCAAAGTCCCTCCTTTTGAAGAATTCTCACTGTGATAAGAACCCTCCCAGCACAG AAGTGGTAATAAAGGAAGAATCGTCACCCAAGAAAGATATGAAGCCAGCCAAGGACCTGA GGCTTCTGTTCAGTAATGAATCTGAGAAGCCGACAACCAACAGCTACCTGATGCAGCACC AGGAGTCCATCATTCAGCTGCAGAAGGCAGGCTTGGTCCGCAAGCACACCAAAGAGCTAG AGCGGCTGAAGAGCGTGCCTGCAGACCCAGCACCTCCCTCCAGGGATGGCCCTGCCAGCA GGCTGGAGGCCAGCATCCCCGAGGAGAGCCAGGATCCAGCCGCGCTCCACGAGCTGGGCC CCCTGGTTATGCCCAGCCAGGCCGGGAGTGATGAGAAGTCAGAGGCCGCCCCCGCTTCAT TGGAAGGAGGCTCACTGAAGAGCCCCCCTCCTTTCTTCTACCGCCTGGACCACACCAGTA GTTTCTCAAAAGACTTTCTGAAGACCATCTGCTACACCCCCACCTCCTCTTCCATGAGCT CCAACCTGACCCGGAGCTCCAGCAGCGATAGCATCCACAGTGTCCGTGGGAAGCCCGGGC TGGTGAAGCAGCGGACGCAGGAGATTGAGACCCGGCTCCGGCTGGCGGGCCTCACCGTCT CTTCCCCACTGAAGCGCTCACACTCTCTTGCCAAGCTGGGGAGTCTCACCTTCTCAACGG AAGACCTGTCCAGTGAGGCTGACCCGTCCACCGTCGCTGACTCCCAGGACACCACTTTGA GTGAATCTTCCTTCTTGCATGAGCCCCAGGGAACCCCGAGGGACCCAGCTGCAACCTCCA AACCATCAGGGAAACCCGCCCCAGAAAACTTAAAGAGCCCTTCGTGGATGAGCAAAAGCT GACCCGCCTTTTGCTGCGTCAGGCTGGGCGGATATTTTCATATGATCCCTCCCTCACTTT CACTGTGGATTTGGATCGACCCCTTACATCTTGATTTCCCTTGAGGGCCCGGCCCGGGCG GCGGTGGCGGTGGCGGCTCTAGCTCGAGACGTCTGTGGCGCCCTCGCACCGCGCCGCAGC CATGGCCCTGGTGACCCTGCAGCGCTCGCCCACGCCCAGCGCCGCCTCCTCCTCGGCCAG CAACAGCGAGTTGGAGGCTGGCAGCGAAGAAGATCGAAAATTAAACCTCAGCTTAAGTGA GAGCTTTTTCATGGTGAAAGGCGCAGCCCTCTTCTTACAACAGGGAAGCAGCCCTCAAGG CCAGCGGAGTCTTCAGCACCCCCACAAGCATGCAGGTGATCTGCCTCAACATCTTCAGGT GATGATCAACCTTCTGCGTTGCGAAGACAGAATCAAGCTGGCAGTGCGCCTGGAGAGCGC CTGGGCGGACCGGGTCCGGTACATGGTGGTGGTGTACAGCAGCGGGCGCCAGGACACCGA GGAGAATATCTTGCTGGGAGTGGACTTTTCCAGTAAGGAAAGTAAAAGCTGCACCATTGG GATGGTTCTCCGACTGTGGAGCGACACGAAAATCCACCTTGATGGAGATGGTGGGTTCAG CGTGAGCACAGCAGGAAGGATGCACATATTTAAGCCTGTGTCTGTCCAGGCCATGTGGTC TGCCCTGCAGGTGCTTCACAAGGCCTGCGAAGTGGCCCGGAGGCACAACTACTTCCCCGG GGGTGTAGCTCTCATCTGGGCTACCTACTATGAGAGCTGCATCAGCTCCGAGCAGAGCTG CATCAACGAGTGGAACGCCATGCAGGACCTGGAGTCTACGCGGCCCGACTCCCCCGCGCT ATTTGTGGACAAGCCCACTGAAGGGGAAAGGACCGAGCGCCTCATCAAAGCCAAGCTCCG AAGCATCATGATGAGCCAGGATCTAGAAAATGTGACTTCCAAAGAGATTCGTAATGAATT AGAGAAACAGATGAATTGTAACTTGAAGGAACTCAAGGAATTTATAGACAATGAGATGCT ACTTATCTTGGGACAGATGGACAAGCCCTCCCTTATCTTCGATCATCTTTATCTCGGTTG ATTACATTTTAAATGTTACCAGAGAAATCGATAATTTTTTTCCTGGCTTATTTGCATATC ATAACATCCGAGTCTACGATGAAGAGACCACAGACCTCCTCGCCCACTGGAATGAAGCGT ATCATTTTATAAACAAAGCGAAGAGGAACCATTCCAAGTGCCTGGTGCATTGCAAAATGG GCGTGAGTCGCTCGGCCTCCACAGTCATAGCCTATGCAATGAAGGAATTCGGCTGGCCTC TGGAAAAAGCATATAACTATGTAAAGCAGAAGCGCAGCATCACGCGCCCCAACGCGGGCT TTATGAGGCAGCTGTCTGAGTATGAAGGCATCTTGGATGCAAGCAAACAGCGGCACAACA AGCTGTGGCGTCAGCAGACAGACAGCAGCCTCCAGCAGCCTGTGGATGACCCTGCAGGAC CTGGCGACTTCTTGCCAGAGACCCCAGATGGCACCCCGGAAAGCCAGCTGCCCTTCTTGG ATGATGCCGCCCAGCCCGGCTTAGGGCCCCCCCTCCCCTGCTGTTTCCGGCGACTCTCAG ACCCCCTTCTGCCTTCCCCTGAGGATGAAACTGGCAGCTTGGTCCACCTGGAGGATCCGG AGAGGGAGGCTCTGTTGGAGGAAGCTGCTCCACCTGCAGAGGTGCACAGGCCGGCCAGAC AGCCCCAGCAAGGTTCCGGACTCTGTGAGAAGGATGTGAAGAAGAAACTAGAGTTTGGGA GTCCCAAAGGTCGGAGCGGCTCCTTGCTGCAGGTGGAGGAGACGGAAAGGGAGGAGGGCC TGGGAGCAGGGAGGTGGGGGCAGCTTCCAACCCAGCTCGATCAAAACCTGCTCAACTCGG AGAACCTAAACAACAACAGCAAGAGGAGCTGTCCCAACGGCATGGAGGATGATGCTATAT TTGGGATCCTTAACAAAGTGAAGCCTTCCTATAAATCCTGTGCCGACTGCATGTACCCTA CAGCCAGCGGGGCTCCTGAGGCCTCCAGGGAGCGATGTGAGGACCCCAATGCTCCCGCCA TCTGCACCCAGCCAGCCTTCCTACCCCACATCACGTCCTCCCCTGTGGCCCACTTGGCCA GCAGGTCCCGTGTTCCGGAGAAGCCAGCCTCTGGCCCAACCGAACCTCCCCCGTTCCTAC CACCAGCAGGCTCCAGGAGGGCAGACACCAGTGGCCCTGGGGCTGGAGCTGCCCTAGAGC CACCAGCCAGCCTTTTGGAACCTTCCAGAGAGACCCCAAAAGTCCTGCCAAAGTCCCTCC TTTTGAAGAATTCTCACTGTGATAAGAACCCTCCCAGCACAGAAGTGGTAATAAAGGAAG AATCGTCACCCAAGAAAGATATGAAGCCAGCCAAGGACCTGAGGCTTCTGTTCAGTAATG AATCTGAGAAGCCGACAACCAACAGCTACCTGATGCAGCACCAGGAGTCCATCATTCAGC TGCAGAAGGCAGGCTTGGTCCGCAAGCACACCAAAGAGCTAGAGCGGCTGAAGAGCGTGC CTGCAGACCCAGCACCTCCCTCCAGGGATGGCCCTGCCAGCAGGCTGGAGGCCAGCATCC CCGAGGAGAGCCAGGATCCAGCCGCGCTCCACGAGCTGGGCCCCCTGGTTATGCCCAGCC AGGCCGGGAGTGATGAGAAGTCAGAGGCCGCCCCCGCTTCATTGGAAGGAGGCTCACTGA AGAGCCCCCCTCCTTTCTTCTACCGCCTGGACCACACCAGTAGTTTCTCAAAAGACTTTC TGAAGACCATCTGCTACACCCCCACCTCCTCTTCCATGAGCTCCAACCTGACCCGGAGCT CCAGCAGCGATAGCATCCACAGTGTCCGTGGGAAGCCCGGGCTGGTGAAGCAGCGGACGC AGGAGATTGAGACCCGGCTCCGGCTGGCGGGCCTCACCGTCTCTTCCCCACTGAAGCGCT CACACTCTCTTGCCAAGCTGGGGAGTCTCACCTTCTCAACGGAAGACCTGTCCAGTGAGG CTGACCCGTCCACCGTCGCTGACTCCCAGGACACCACTTTGAGTGAATCTTCCTTCTTGC ATGAGCCCCAGGGAACCCCGAGGGACCCAGCTGCAACCTCCAAACCATCAGGGAAACCCG CCCCAGAAAACTTAAAGAGCCCTTCGTGGATGAGCAAAAGCTGACCCGCCTTTTGCTGCG TCAGGCTGGGCGGATATTTTCATATGATCCCTCCCTCACTTTCACTGTGGATTTGGATCG ACCCCTTACATCTTGATTTCCCTT >OriGene 5' read for NM_018984 unedited
NGGGGGCCACATTTGTAAACCATTACTATAGGCGGCCGCGCAATTCGCACGAGGGCCCGG CCCGGGCGGCGGTGGCGGTGGCGGCTCTAGCTCGAGACGTCTGTGGCGCCCTCGCACCGC GCCGCAGCCATGGCCCTGGTGACCCTGCAGCGCTCGCCCACGCCCAGCGCCGCCTCCTCC TCGGCCAGCAACAGCGAGTTGGAGGCTGGCAGCGAAGAAGATCGAAAATTAAACCTCAGC TTAAGTGAGAGCTTTTTCATGGTGAAAGGCGCAGCCCTCTTCTTACAACAGGGAAGCAGC CCTCAAGGCCAGCGGAGTCTTCAGCACCCCCACAAGCATGCAGGTGATCTGCCTCAACAT CTTCAGGTGATGATCAACCTTCTGCGTTGCGAAGACAGAATCAAGCTGGCAGTGCGCCTG GAGAGCGCCTGGGCGGACCGGGTCCGGTACATGGTGGTGGTGTACAGCAGCGGGCGCCAG GACACCGAGGAGAATATCTTGCTGGGAGTGGACTTTTCCAGTAAGGAAAGTAAAAGCTGC ACCATTGGGATGGTTCTCCGACTGTGGAGCGACACGAAAATCCACCTTGATGGAGATGGT GGGTTCAGCGTGAGCACAGCAGGAAGGATGCACATATTTAAGCCTGTGTCTGTCCAGGCC ATGTGGTCTGCCCTGCAGGTGCTTCACAAGGCCTGCGAAGTGGCCCGGAGCACAACTACT TCCCCGGGGGTGTAGCTCTCATCTGGGCTACCTACTATGAGAGCTGCATCAGCTCCGAGC AAAGCTGCNTCAACGAAGTGAACGCCATGCAAGACCTGTGATCTACGCGGCCCGACTCCC CCGCGCTATTTGTGGACAACCCCACTGAAGGGGAAATGAACCGAGCGCCTCATCCAGCCA AGCTCCGAAAACATCTGATGAACCAGN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018984 |
| Insert Size | 5300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018984.2, NP_061857.2 |
| RefSeq Size | 4083 bp |
| RefSeq ORF | 3150 bp |
| Locus ID | 54434 |
| UniProt ID | Q8WYL5 |
| Domains | DSPc |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Regulation of actin cytoskeleton |
| Gene Summary | The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as SSH-1L). This isoform has been shown to be enzymatically active (PMID:11832213). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209121 | SSH1 (Myc-DDK-tagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 1 |
CNY 7,304.00 |
|
| RC209121L3 | Lenti-ORF clone of SSH1 (Myc-DDK-tagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 1 |
CNY 12,350.00 |
|
| RC209121L4 | Lenti-ORF clone of SSH1 (mGFP-tagged)-Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 1 |
CNY 12,350.00 |
|
| RG209121 | SSH1 (tGFP-tagged) - Human slingshot homolog 1 (Drosophila) (SSH1), transcript variant 1 |
CNY 8,904.00 |
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