PTPRN2 (NM_002847) Human Untagged Clone

CAT#: SC120495

PTPRN2 (untagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1



  "NM_002847" in other vectors (4)

CNY 10,608.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
PTPRN2 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC120495 sequence for NM_002847 edited (data generated by NextGen Sequencing)
ATGGGGCCGCCGCTCCCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCACGCGTCCTG
CCTGCCGCCCCTTCGTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTG
CTCGAGGAGGGCCTCTGCGGAGCGTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGG
TGCCAGAAGGTTCCGGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAG
CGCCTGCGCGTGGCGTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTAT
ACTCAGTATGTGATGGACCAGGAACTTGCAGACCTCCCGAAAACCTACCTGAGGCGTCCT
GAAGCATCCAGCCCAGCCAGGCCCTCAAAACACAGCGTTGGCAGCGAGAGGAGGTACAGT
CGGGAGGGCGGTGCTGCCCTGGCCAACGCCCTCCGACGCCACCTGCCCTTCCTGGAGGCC
CTGTCCCAGGCCCCAGCCTCAGACGTGCTCGCCAGGACCCATACGGCGCAGGACAGACCC
CCCGCTGAGGGTGATGACCGCTTCTCCGAGAGCATCCTGACCTATGTGGCCCACACGTCT
GCGCTGACCTACCCTCCCGGGCCCCGGACCCAGCTCCGCGAGGACCTCCTGCCGCGGACC
CTCGGCCAGCTCCAGCCAGATGAGCTCAGCCCTAAGGTGGACAGTGGTGTGGACAGACAC
CATCTGATGGCGGCCCTCAGTGCCTATGCTGCCCAGAGGCCCCCAGCTCCCCCCGGGGAG
GGCAGCCTGGAGCCACAGTACCTTCTGCGTGCACCCTCAAGAATGCCCAGGCCTTTGCTG
GCACCAGCCGCCCCCCAGAAGTGGCCTTCACCTCTGGGAGATTCCGAAGACCCCTCTAGC
ACAGGCGATGGAGCACGGATTCATACCCTCCTGAAGGACCTGCAGAGGCAGCCGGCTGAG
GTGAGGGGCCTGAATGGCCTGGAGCTGGACGGCATGGCCGAGCTGATGGCTGGCCTGATG
CAAGGCGTGGACCATGGAGTAGCTCGAGGCAGCCCTGGGAGAGCGGCCCTGGGAGAGTCT
GGAGAACAGGCGGATGGCCCCAAGGCCACCCTCCGTGGAGACAGCTTTCCAGATGACGGA
GTGCAGGACGACGATGATAGACTTTACCAAGAGGTCCATCGTCTGAGTGCCACACTCGGG
GGCCTCCTGCAGGACCACGGGTCTCGACTCTTACCTGGAGCCCTCCCCTTTGCAAGGCCC
CTCGACATGGAGAGGAAGAAGTCCGAGCACCCTGAGTCTTCCCTGTCTTCAGAAGAGGAG
ACTGCCGGAGTGGAGAACGTCAAGAGCCAGACGTATTCCAAAGATCTGCTGGGGCAGCAG
CCGCATTCGGAGCCCGGGGCCGCTGCGTTTGGGGAGCTCCAAAACCAGATGCCTGGGCCC
TCGAAGGAGGAGCAGAGCCTTCCAGCGGGTGCTCAGGAGGCCCTCAGCGACGGCCTGCAA
TTGGAGGTCCAGCCTTCCGAGGAAGAGGCGCGGGGCTACATCGTGACAGACAGAGACCCC
CTGCGCCCCGAGGAAGGAAGGCGGCTGGTGGAGGACGTCGCCCGCCTCCTGCAGGTGCCC
AGCAGTGCGTTCGCTGACGTGGAGGTTCTCGGACCAGCAGTGACCTTCAAAGTGAGCGCC
AATGTCCAAAACGTGACCACTGAGGATGTGGAGAAGGCCACAGTTGACAACAAAGACAAA
CTGGAGGAAACCTCTGGACTGAAAATTCTTCAAACCGGAGTCGGGTCGAAAAGCAAACTC
AAGTTCCTGCCTCCTCAGGCGGAGCAAGAAGACTCCACCAAGTTCATCGCGCTCACCCTG
GTCTCCCTCGCCTGCATCCTGGGCGTCCTCCTGGCCTCTGGCCTCATCTACTGCCTCCGC
CATAGCTCTCAGCACAGGCTGAAGGAGAAGCTCTCGGGACTAGGGGGCGACCCAGGTGCA
GATGCCACTGCCGCCTACCAGGAGCTGTGCCGCCAGCGTATGGCCACGCGGCCACCAGAC
CGACCTGAGGGCCCGCACACGTCACGCATCAGCAGCGTCTCATCCCAGTTCAGCGACGGG
CCGATCCCCAGCCCCTCCGCACGCAGCAGCGCCTCATCCTGGTCCGAGGAGCCTGTGCAG
TCCAACATGGACATCTCCACCGGCCACATGATCCTGTCCTACATGGAGGACCACCTGAAG
AACAAGAACCGGCTGGAGAAGGAGTGGGAAGCGCTGTGCGCCTACCAGGCGGAGCCCAAC
AGCTCGTTCGTGGCCCAGAGGGAGGAGAACGTGCCCAAGAACCGCTCCCTGGCCGTGCTG
ACCTATGACCACTCCCGGGTCCTGCTGAAGGCGGAGAACAGCCACAGCCACTCAGACTAC
ATCAACGCTAGCCCCATCATGGATCACGACCCGAGGAACCCCGCGTACATCGCCACCCAG
GGACCGCTGCCCGCCACCGTGGCTGACTTTTGGCAGATGGTGTGGGAGAGCGGCTGCGTG
GTGATCGTCATGCTGACACCCCTCGCGGAGAACGGCGTCCGGCAGTGCTACCACTACTGG
CCGGATGAAGGCTCCAATCTCTACCACATCTATGAGGTGAACCTGGTCTCCGAGCACATC
TGGTGTGAGGACTTCCTGGTGAGGAGCTTCTATCTGAAGAACCTGCAGACCAACGAGACG
CGCACCGTGACGCAGTTCCACTTCCTGAGTTGGTATGACCGAGGAGTCCCTTCCTCCTCA
AGGTCCCTCCTGGACTTCCGCAGAAAAGTAAACAAGTGCTACAGGGGCCGTTCTTGTCCA
ATAATTGTTCATTGCAGTGACGGTGCAGGCCGGAGCGGCACCTACGTCCTGATCGACATG
GTTCTCAACAAGATGGCCAAAGGTGCTAAAGAGATTGATATCGCAGCGACCCTGGAGCAC
TTGAGGGACCAGAGACCCGGCATGGTCCAGACGAAGGAGCAGTTTGAGTTCGCGCTGACA
GCCGTGGCTGAGGAGGTGAACGCCATCCTCAAGGCCCTTCCCCAGTGA

Clone variation with respect to NM_002847.3
622 t=>c;897 c=>t;974 g=>a;999 t=>c
>OriGene 5' read for NM_002847 unedited
GCCCCGTTGACGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTC
ATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGG
CACGAGGGAGGAGCCGGCGGCGCGCGCCTCCCTGGGCCCGGACTCGGCCGCCTCCCGCCG
CCTCCCGCGCGGCCATGGACTGAGCGCCGCCGGCCAGGCCGCGGGGATGGGGCCGCCGCT
CCCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCACGCGTCCTGCCTGCCGCCCCTTC
GTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTGCTCGAGGAGGGCCT
CTGCGGAGCGTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGGTGCCAGAAGGTTCC
GGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAGCGCCTGCGCGTGGC
GTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTATACTCAGTATGTGAT
GGACCAGGAACTTGCAGACCTCCCGAAAACCTACCTGAGGCGTCCTGAAGCATCCAGCCC
AGCCAGGCCCTCAAACACAGCGTTGGCAGCGAGAGGAGGTACAGTCGGGAGGGCGGTGCT
GNCCTGGNNCAACGCCTNCGACGCCACCTGGCCTTTCTGGGAGCCCTGTNCCAGGCCCCA
GCCTCAGACGTGCTCGCCAGGACCATACNGNGCANGACAGACCCCCGCCTGAGGTGATGA
CCGCTCCTNCGAGAGCATCCTGACCTATGTGGNCCACACGTNTGCGCTGACCTACCCCTC
CGGNCCCCGGACCAGCTCCGCGAGGACCCTCTGGCGGGNACCCTCGCCAGCTNCAGCCAG
ATGAGCTCAGCCCTAGGTGGAACGGGGNNTGGGGACAGAACCCCATCTGATGGCGGCCCT
CAGTGGCTATGCTGGCCAGAGGCCCCAGCTCCCGCGGGGGGAGGGCAAGCTGGAGGCCAC
GAACCTNNTGGGTGCACCTNAAA
>OriGene 3' genomic read for NM_002847 unedited
ACTATGGTACCGCGGCCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTGTGAAATC
AGAGTTTAATATGACACAATTAAATATATTTGTATATCTCACACCGGAGGTTTCTCTTCA
AACATAAGGAGTTAGAAATTACAAGTAGGCATATGCTTCCTATATTCAGATAAATTCATT
TCGATTAATTAAATTCCAGATAGAGAGAAGTAATTTTGGAAAAGAAATGATAGCTATATT
AAAGCAGATATTCATTACAATACCATGTAGAGACATAAGCAATATTTTGGCATCATTCTG
TCCGCTCAGTAGGCCGTGTTCCCTCTGGTAGGGCCTTTGGAGAGTACCATCTATCTAAGA
TGGAGGAATGCTGTGGGAAGGGCGGGATGGAGGTGCGTTTTCTACGCTGAACCCCACACA
GGAAATCTGCAGCCCACACAGCTGCCTCTGCGCCGCCTTCCATGTGATCATCCTGGTCAA
TGAAGTGAATTGTCCTATTTCTGGGGTAGGGGGTGATGGCGAATCGGATACTCAAATGTT
ATTTTGTCAAATCCGAATCATCTCTACGTGCTTAGGTTTACATGATGTCAAAACACGTGG
TTCATTAAGTGATCCCGGGAAGAGGGGCAGGGCCGGTCGGCTGGTTTCTCACTTCCCTTC
CAGGCTCTACGCAGTGCGTGCAGGTCGCCCTGATCTCTCCCGGGAGGGGAATGCTCGCAG
CCCTCTCCGAGNTGCCCTGATCTCCTTCTCTCCCAGAGGGAAATGGTCCCTCTCTGGGGC
CCCACAGTCCCGGACGTGCCTGGAGAGCCAGCGGGGCCTGGCAGGGNTCGTGTGCTCCCG
GGGACCCTCTAGCTTGCTCAAGCCCAGATTGTTCTTCCTGTTGTGGTATCTCACAGGTAG
CTTCACGGGGCATCGTTTTCATACGGAAAAACATTATTTACT
Restriction Sites NotI-NotI     
ACCN NM_002847
Insert Size 5500 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_002847.2, NP_002838.1
RefSeq Size 4767 bp
RefSeq ORF 3048 bp
Locus ID 5799
UniProt ID Q92932
Domains Y_phosphatase, PTPc_motif
Protein Families Druggable Genome, Phosphatase
Protein Pathways Type I diabetes mellitus
Gene Summary This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Transcript Variant: This variant (1) encodes isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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