United States
Germany
Japan
United Kingdom
China
VPS26B (NM_052875) Human Untagged Clone
CAT＃: SC120157
VPS26B (untagged)-Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Pep8b |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120157 sequence for NM_052875 edited (data generated by NextGen Sequencing)
ATGAGCTTCTTCGGCTTCGGGCAGAGCGTGGAGGTGGAAATCCTTCTGAACGATGCAGAG AGTAGGAAGCGGGCCGAGCACAAGACGGAGGACGGGAAGAAGGAGAAATATTTCCTCTTC TACGACGGGGAGACGGTCTCCGGGAAGGTGAGCCTTGCCCTCAAGAACCCCAACAAGCGG CTGGAGCACCAGGGCATCAAGATCGAGTTCATCGGGCAGATCGAACTCTACTACGATCGC GGGAACCACCATGAGTTTGTGTCCCTGGTGAAGGACCTGGCCCGGCCTGGAGAGATCACC CAGTCGCAGGCCTTCGACTTTGAGTTTACCCACGTGGAGAAGCCGTATGAGTCCTACACA GGGCAGAATGTGAAGCTACGCTATTTCCTTCGTGCTACCATCAGCCGCCGCCTCAATGAT GTTGTCAAAGAGATGGACATTGTAGTTCACACACTCAGCACATACCCAGAGCTGAACTCT TCCATCAAGATGGAGGTTGGGATTGAGGACTGTCTGCACATTGAATTTGAGTACAATAAA TCCAAATACCACTTGAAAGATGTCATTGTAGGGAAGATATACTTCCTGCTGGTGAGAATC AAAATCAAGCACATGGAGATAGACATCATCAAGCGAGAAACGACGGGTACAGGCCCCAAC GTGTACCATGAGAATGACACGATAGCCAAGTACGAGATCATGGACGGGGCACCAGTGCGA GGAGAGTCCATCCCGATCCGGCTCTTCCTGGCCGGGTATGAGCTCACGCCCACCATGCGG GACATCAACAAGAAGTTCTCTGTGCGCTATTACCTCAACCTGGTGCTGATAGACGAGGAG GAGCGGCGCTACTTCAAGCAGCAGGAAGTGGTGTTGTGGCGGAAGGGTGACATCGTACGG AAGAGCATGTCCCACCAGGCGGCCATCGCCTCACAGCGCTTTGAGGGCACCACCTCCCTG GGTGAGGTGCGGACCCCCAGCCAGCTGTCTGACAACAACTGCAGGCAGTAG Clone variation with respect to NM_052875.3 >OriGene 5' read for NM_052875 unedited
NGTTACATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGNAGACCCGCCC GGCCCGGCGGTGCGATGAGCTTCTTCGGCTTCGGGCAGAGCGTGGAGGTGGAAATCCTTC TGAACGATGCAGAGAGTAGGAAGCGGGCCGAGCACAAGACGGAGGACGGGAAGAAGGAGA AATATTTCCTCTTCTACGACGGGGAGACGGTCTCCGGGAAGGTGAGCCTTGCCCTCAAGA ACCCCAACAAGCGGCTGGAGCACCAGGGCATCAAGATCGAGTTCATCGGGCAGATCGAAC TCTACTACGATCGCGGGAACCACCATGAGTTTGTGTCCCTGGTGAAGGACCTGGCCCGGC CTGGAGAGATCACCCAGTCGCAGGCCTTCGACTTTGAGTTTACCCACGTGGAGAAGCCGT ATGAGTCCTACACAGGGCAGAATGTGAAGCTACGCTATTTCCTTCGTGCTACCATCAGCC GCCGCCTCAATGATGTTGTCAAAGAGATGGACATTGTAGTTCACACACTCAGCACATACC CAGAGCTGAACTCTTCCATCAAGATGGAGGTTGGGATTGAGGACTGTCTGCACATTGAAT TTGAGTACAATAAATCCAAATACCACTTGAAAGATGTCATTGTAGGGAAGATATACTTCC TGCTGGTGAGAATCAAAATCAAGCACATGGAGATAGACATCATCAAGCGAGAAACGACGG GTACAGGCCCCAACGTGTACCATGAGAATGACACGATAGCCAAGTACGAGATCATGGACG GGGCACCAGTGCGAGGAGAAGTCATNCCGATCCGGCTCTTTCTGGCCGGGTATGAGCTCA CGCCACCATGCGGNACATCANCAGAAGTNCTCTGTGCGCTATACCCTCAACTGGTGCTGA TAGACGAGGAGGAGCGGCGCTACTTCAGCCCAGNAANTGGNTGTGTGGCGGAAGGGTGAC ATCGTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_052875 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_052875.2, NP_443107.1 |
| RefSeq Size | 1617 bp |
| RefSeq ORF | 1011 bp |
| Locus ID | 112936 |
| UniProt ID | Q4G0F5 |
| Domains | Vps26 |
| Gene Summary | Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210499 | VPS26B (Myc-DDK-tagged)-Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B) |
CNY 3,656.00 |
|
| RC210499L1 | Lenti-ORF clone of VPS26B (Myc-DDK-tagged)-Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B) |
CNY 6,056.00 |
|
| RC210499L2 | Lenti-ORF clone of VPS26B (mGFP-tagged)-Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B) |
CNY 5,890.00 |
|
| RC210499L3 | Lenti-ORF clone of VPS26B (Myc-DDK-tagged)-Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B) |
CNY 6,056.00 |
|
| RC210499L4 | Lenti-ORF clone of VPS26B (mGFP-tagged)-Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B) |
CNY 5,890.00 |
|
| RG210499 | VPS26B (tGFP-tagged) - Human vacuolar protein sorting 26 homolog B (S. pombe) (VPS26B) |
CNY 4,370.00 |
