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HFE (NM_000410) Human Untagged Clone
CAT＃: SC119914
HFE (untagged)-Human hemochromatosis (HFE), transcript variant 1
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HFE1; HH; HLA-H; MVCD7; TFQTL2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119914 sequence for NM_000410 edited (data generated by NextGen Sequencing)
ATGGGCCCGCGAGCCAGGCCGGCGCTTCTCCTCCTGATGCTTTTGCAGACCGCGGTCCTG CAGGGGCGCTTGCTGCGTTCACACTCTCTGCACTACCTCTTCATGGGTGCCTCAGAGCAG GACCTTGGTCTTTCCTTGTTTGAAGCTTTGGGCTACGTGGATGACCAGCTGTTCGTGTTC TATGATCATGAGAGTCGCCGTGTGGAGCCCCGAACTCCATGGGTTTCCAGTAGAATTTCA AGCCAGATGTGGCTGCAGCTGAGTCAGAGTCTGAAAGGGTGGGATCACATGTTCACTGTT GACTTCTGGACTATTATGGAAAATCACAACCACAGCAAGGAGTCCCACACCCTGCAGGTC ATCCTGGGCTGTGAAATGCAAGAAGACAACAGTACTGAGGGCTACTGGAAGTACGGGTAT GATGGGCAGGACCACCTTGAATTCTGCCCTGACACACTGGATTGGAGAGCAGCAGAACCC AGGGCCTGGCCCACCAAGCTGGAGTGGGAAAGGCACAAGATTCGGGCCAGGCAGAACAGG GCCTACCTGGAGAGGGACTGCCCTGCACAGCTGCAGCAGTTGCTGGAGCTGGGGAGAGGT GTTTTGGACCAACAAGTGCCTCCTTTGGTGAAGGTGACACATCATGTGACCTCTTCAGTG ACCACTCTACGGTGTCGGGCCTTGAACTACTACCCCCAGAACATCACCATGAAGTGGCTG AAGGATAAGCAGCCAATGGATGCCAAGGAGTTCGAACCTAAAGACGTATTGCCCAATGGG GATGGGACCTACCAGGGCTGGATAACCTTGGCTGTACCCCCTGGGGAAGAGCAGAGATAT ACGTGCCAGGTGGAGCACCCAGGCCTGGATCAGCCCCTCATTGTGATCTGGGAGCCCTCA CCGTCTGGCACCCTAGTCATTGGAGTCATCAGTGGAATTGCTGTTTTTGTCGTCATCTTG TTCATTGGAATTTTGTTCATAATATTAAGGAAGAGGCAGGGTTCAAGAGGAGCCATGGGG CACTACGTCTTAGCTGAACGTGAGTGA Clone variation with respect to NM_000410.3 396 c=>t >OriGene 5' read for NM_000410 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCCCCCCAAAAGAA GCGGAGATTTAACGGGGACGTGCGGCCAGAGCTGGGGAAATGGGCCCGCGAGCCAGGCCG GCGCTTCTCCTCCTGATGCTTTTGCAGACCGCGGTCCTGCAGGGGCGCTTGCTGCGTTCA CACTCTCTGCACTACCTCTTCATGGGTGCCTCAGAGCAGGACCTTGGTCTTTCCTTGTTT GAAGCTTTGGGCTACGTGGATGACCAGCTGTTCGTGTTCTATGATCATGAGAGTCGCCGT GTGGAGCCCCGAACTCCATGGGTTTCCAGTAGAATTTCAAGCCAGATGTGGCTGCAGCTG AGTCAGAGTCTGAAAGGGTGGGATCACATGTTCACTGTTGACTTCTGGACTATTATGGAA AATCACAACCACAGCAAGGAGTCCCACACCCTGCAGGTCATCCTGGGCTGTGAAATGCAA GAAGACAACAGTACTGAGGGCTACTGGAAGTACGGGTATGATGGGCAGGACCACCTTGAA TTCTGCCCTGACACACTGGATTGGAGAGCAGCAGAACCCAGGGCCTGGCCCACCAAGCTG GAGTGGGAAAGGCACAAGATTCGGGCCAGGCAGAACAGGGCCTACCTGGAGAGGGACTGC CCTGCACAGCTGCANCAGTTGCTGGAGCTGGGGAGAGGTGTTTTGGACCAACAGTGCCTC CTTTGGTGAAGTGACACATCATGTGACCTCTTCAGTGACCACTCTACGGTGTCGGNCCTT GAACTACTANCCCCAGACATCACCATGAAGTGGCTGAAGGATAGCAGCCATGGATGCCAN GNAGNTCGAACCTAAGACGTATTGCCCATGGNGGATGGGACCTACCANGGCTGGATACCN TNGNCTGTANCCCCTGNAGNAGAGCANANAATACGC >OriGene 3' read for NM_000410 unedited
AACGCGGCCACTATCTAGAGTCGAGNTCTTTTTTTTTTTTTTTTTTTACTTTTTTTTTTT GAAAAGGAGTCTCACTTTGTTACCTTAAGCTGGTATTGCATTGTTTTCAAACTTTTTTTT ACTGTTATCTTTGTCTTTTGGGTTCATGCCTTTTTTCTGCCTTATTCTTTCTATTACTTG GGACTACAGGCGTCCGTCACCACGCCCATTTAATTTTTTGTATTTTTACTAAAAATGGGG TTTCACCATGTTACCCATGATGGTCTCGATCTCCTGACCTCGCGATCCACCCGCTTTGGC CTCCCAAAGCGCTGGGATTACAGGCGTGAGCCAACGGGCCCGGCCTACTTATCTTTCTTC ATTTAAAAAAGAAATGGGGATAATAGCACCTATCTCATAAAATTATTGTAACAAGTGCAT GCAGTAATGCATGCAAACACGCGCCCAAAACACTCCGACACCAACTAACTGCCCTTATCA TCCTTATCATAATTCCCATTTTCAAAACAAGGAGAGACCAGGTAGAAAATTATTGGGATT CTTCAGGGCCGGAATACCAAAGTAGCATTCCAAATGAAAGCACCATTAAACTTCTGCAAT CCGTATGACACCCTTCATGCCAATAGAAAATACCACTTTTACAACCCCTTTAAAAATTTC CCTCCTACCCCGCTAAAACCCCATCTTCCTCCCACAGATATCCCGAAGCTTCTTTTGGAC AAGTGCCTTTTTATTTCCGCAGCGCCAGGCTTATTCATGGGAACCGACATTAAATCACAA GGAATAACCCCCAAGCTTTGTGACAAATGAGCCCCGGGAACACAAGAAAAGGGTTCACAG GAAAATTTAACGCGCCCCAAAATCGCTCAACCCCGGCGAAAATCCCGTAAGGTTAAACTC ACCCCTTCCCAGGGGAAAAATNTTCTTAAAGTGAAAAGAATCCGGAACCCCCAAATAAGG GATCCCTTCCAAAAGGAAAGAAACCCATAGGCACTTTTCAGCGCCGGAAAAGAGN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000410 |
| Insert Size | 2820 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000410.2, NP_000401.1 |
| RefSeq Size | 2727 bp |
| RefSeq ORF | 1047 bp |
| Locus ID | 3077 |
| UniProt ID | Q30201 |
| Domains | MHC_I, ig, IGc1 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longest isoform. CCDS Note: This CCDS ID represents the longest isoform encoded by the HFE gene. This isoform contains both a Class I Histocompatibility antigen (MHC_I) and an Immunoglobulin constant region (IGc) domain. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217447 | HFE (Myc-DDK-tagged)-Human hemochromatosis (HFE), transcript variant 1 |
CNY 3,656.00 |
|
| RC217447L1 | Lenti ORF clone of Human hemochromatosis (HFE), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC217447L2 | Lenti ORF clone of Human hemochromatosis (HFE), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC217447L3 | Lenti ORF clone of Human hemochromatosis (HFE), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217447L4 | Lenti ORF clone of Human hemochromatosis (HFE), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG217447 | HFE (tGFP-tagged) - Human hemochromatosis (HFE), transcript variant 1 |
CNY 5,256.00 |
