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CD53 (NM_000560) Human Untagged Clone
CAT＃: SC119837
CD53 (untagged)-Human CD53 molecule (CD53), transcript variant 2
CNY 3,600.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MOX44; TSPAN25 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000560, the custom clone sequence may differ by one or more nucleotides
ATGGGCATGAGTAGCTTGAAACTGCTGAAGTATGTCCTGTTTTTCTTCAACTTGCTCTTTTGGATCTGTG GCTGCTGCATTTTGGGCTTTGGGATCTACCTGCTGATCCACAACAACTTCGGAGTGCTCTTCCATAACCT CCCCTCCCTCACGCTGGGCAATGTGTTTGTCATCGTGGGCTCTATTATCATGGTAGTTGCCTTCCTGGGC TGCATGGGCTCTATCAAGGAAAACAAGTGTCTGCTTATGTCGTTCTTCATCCTGCTGCTGATTATCCTCC TTGCTGAGGTGACCTTGGCCATCCTGCTCTTTGTATATGAACAGAAGCTGAATGAGTATGTGGCTAAGGG TCTGACCGACAGCATCCACCGTTACCACTCAGACAATAGCACCAAGGCAGCGTGGGACTCCATCCAGTCA TTTCTGCAGTGTTGTGGTATAAATGGCACGAGTGATTGGACCAGTGGCCCACCAGCATCTTGCCCCTCAG ATCGAAAAGTGGAGGGTTGCTATGCGAAAGCAAGACTGTGGTTTCATTCCAATTTCCTGTATATCGGAAT CATCACCATCTGTGTATGTGTGATTGAGGTGTTGGGGATGTCCTTTGCACTGACCCTGAACTGCCAGATT GACAAAACCAGCCAGACCATAGGGCTATGA >OriGene 5' read for NM_000560 unedited
NNCCGCGTTCACGATTTGTAATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGG CGGATATCTGTGTTACCAGCCTTGTCTCGGCCACCTCAAGGATAATCACTAAATTCTGCC GAAAGGACTGAGGAACGGTGCCTGGAAAAGGGCAAGAATATCACGGCATGGGCATGAGTA GCTTGAAACTGCTGAAGTATGTCCTGTTTTTCTTCAACTTGCTCTTTTGGATCTGTGGCT GCTGCATTTTGGGCTTTGGGATCTACCTGCTGATCCACAACAACTTCGGAGTGCTCTTCC ATAACCTCCCCTCCCTCACGCTGGGCAATGTGTTTGTCATCGTGGGCTCTATTATCATGG TAGTTGCCTTCCTGGGCTGCATGGGCTCTATCAAGGAAAACAAGTGTCTGCTTATGTCGT TCTTCATCCTGCTGCTGATTATCCTCCTTGCTGAGGTGACCTTGGCCATCCTGCTCTTTG TATATGAACAGAAGCTGAATGAGTATGTGGCTAAGGGTCTGACCGACAGCATCCACCGTT ACCACTCAGACAATAGCACCAAGGCAGCGTGGGACTCCATCCAGTCATTTCTGCAGTGTT GTGGTATAAATGGCACGAGTGATTGGACCAGTGGCCCACCAGCATCTTGCCCCTCAGATC GAANAGTGGAGGGTTGCTATGCGAAAGCAAGACTGTGGTTTCATTCCAATTTCCTGTATA TCGGAATCATCACCATCTGTGTATGTGTGATTGAGGTGTGGGGGGATGTCCTTTGCACTG ACCCTNGACTGCCAGATTGANCAAACCAGCCAGACCATANGGCTATGATCTGCAGTAGTC CTGTGGTGAAGAGACTTGTTTCATCTCCAGAAATGCAAACCATTTATAGCATGAAGCCCT ACATGATCACTGC >OriGene 3' read for NM_000560 unedited
GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGATAATAAACTTTTATTTATTGAA GAGTAAAATAGTACATTAACAAAATCTTATCTGATAGAGAGATAATACCAGAAGTCTTCT TACTGTGATTATCAGCTAAGTGACTGGTTGAAATCAGGATATAAATCACTGGATAGTTTT TTTCTGGAAAGACTTAGAACACATCAATAAGGCCCTCTAATAAAGAAATTGAAATGAACT CTTGCCCTTTGGAGAAAGAGAACTGTGTAATTCCTGTAGCCAGGGCACTTATTCAAAGAG AAACAGAGGGTTGTGACAATGGTCCAGTGAGCCTGGCCCCAGAACTCCCTTCAACTAGTC TCTTGCTTGACTTTGGGGAGAAGACTGGGCATTATTTAGAGGCTGGAGACTAATTCGACA ATGGGAAGATGCAAAAATTCATATCCTGGGTTCACCCTTTGATGTTGGGCCATTAAATCC AGTTTGTCTTTGCCTCTCTTGTCTAAAAGATGCTCAGATATTAGTTTCACCACTTTGAGA GACATGGCTGCTGCCGTCAGTGAGTGAAAGATTGTCTTGCTGCCTGAGATGGGATGTGCC TGGCCCAACACCCACTTCTCTGGTTGTATTAGACAGGGACCTAAAAAGGGAAAGGATGGG AGGAAGATCATCCTGCAGTGATCATGTAAGGCTTCATGCTATAAATGCTCTTGCATTTTC GGAGATGAAACAAGCCTCTTCACCACAGGACTACTGCAGATCATAGCCCTATGTTCTGCC TGGTTTGGTCATNCTGGCAGTTCAAGTTCAGTGCCAAGGAAATTCCAACACCTCAATACA CTTACCACGATGTGGATGATTCCCAATTCCAGGAAATTGGATGAAACCACGCTTGGTTTG CAAATCACCCTTACTTTTCAATCTAGNGCGAGATGCTGGGGGCCACTGTCCAATCACGGG CCTTTTACCCAACCCGCGAATGACGTAGGGTCCCCCTGCTCGTGCTTGGTGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000560 |
| Insert Size | 1530 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000560.2, NP_000551.1 |
| RefSeq Size | 1567 bp |
| RefSeq ORF | 660 bp |
| Locus ID | 963 |
| UniProt ID | P19397 |
| Domains | transmembrane4 |
| Protein Families | Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208095 | CD53 (Myc-DDK-tagged)-Human CD53 molecule (CD53), transcript variant 2 |
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| RC208095L3 | Lenti ORF clone of Human CD53 molecule (CD53), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC208095L4 | Lenti ORF clone of Human CD53 molecule (CD53), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG208095 | CD53 (tGFP-tagged) - Human CD53 molecule (CD53), transcript variant 2 |
CNY 5,200.00 |
