CYP51A1 (NM_000786) Human Untagged Clone

CAT#: SC119686

CYP51A1 (untagged)-Human cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1), transcript variant 1



  "NM_000786" in other vectors (5)

CNY 3,800.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
CYP51A1 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119686 sequence for NM_000786 edited (data generated by NextGen Sequencing)
ATGGCGGCGGCGGCTGGGATGCTGCTGCTGGGCTTGCTGCAGGCGGGTGGGTCGGTGCTG
GGCCAGGCGATGGAGAAGGTGACAGGCGGCAACCTCTTGTCCATGCTGCTGATCGCCTGC
GCCTTCACCCTCAGCCTGGTCTACCTGATCCGTCTGGCCGCCGGCCACCTGGTCCAGCTG
CCCGCAGGGGTGAAAAGTCCTCCATACATTTTCTCCCCAATTCCATTCCTTGGGCATGCC
ATAGCATTTGGGAAAAGTCCAATTGAATTTCTAGAAAATGCATATGAGAAGTATGGACCT
GTATTTAGTTTTACCATGGTAGGCAAGACATTTACTTACCTTCTGGGGAGTGATGCTGCT
GCACTGCTTTTTAATAGTAAAAATGAAGACCTGAATGCAGAAGATGTCTACAGTCGCCTG
ACAACACCTGTGTTTGGGAAGGGAGTTGCATACGATGTGCCTAATCCAGTTTTCTTGGAG
CAGAAGAAAATGTTAAAAAGTGGCCTTAACATAGCCCACTTTAAACAGCATGTTTCTATA
ATTGAAAAAGAAACAAAGGAATACTTTGAGAGTTGGGGAGAAAGTGGAGAAAAAAATGTG
TTTGAAGCTCTTTCTGAGCTCATAATTTTAACAGCTAGCCATTGTTTGCATGGAAAGGAA
ATCAGAAGTCAACTCAATGAAAAGGTAGCACAGCTGTATGCAGATTTGGATGGAGGTTTC
AGCCATGCAGCCTGGCTCTTACCAGGTTGGCTGCCTTTGCCTAGTTTCAGACGCAGGGAC
AGAGCTCATCGGGAAATCAAGGATATTTTCTATAAGGCAATCCAGAAACGCAGACAGTCT
CAAGAAAAAATTGATGACATTCTCCAAACTTTACTAGATGCTACATACAAGGATGGGCGT
CCTTTGACTGATGATGAAGTAGCAGGGATGCTTATTGGATTACTCTTGGCAGGGCAGCAT
ACATCCTCAACTACTAGTGCTTGGATGGGCTTCTTTTTGGCCAGAGACAAAACACTTCAA
AAAAAATGTTATTTAGAACAGAAAACAGTCTGTGGAGAGAATCTGCCTCCTTTAACTTAT
GACCAGCTCAAGGATCTAAATTTACTTGATCGCTGTATAAAAGAAACATTAAGACTTAGA
CCTCCTATAATGATCATGATGAGAATGGCCAGAACTCCTCAGACTGTGGCAGGGTATACC
ATTCCTCCAGGACATCAGGTGTGTGTTTCTCCCACTGTCAATCAAAGACTTAAAGACTCA
TGGGTAGAACGCCTGGACTTTAATCCTGATCGCTACTTACAGGATAACCCAGCATCAGGG
GAAAAGTTTGCCTATGTGCCATTTGGAGCTGGGCGTCACCGTTGTATTGGGGAAAATTTT
GCCTATGTTCAAATTAAGACAATTTGGTCCACTATGCTTCGTTTATATGAATTTGATCTC
ATTGATGGATACTTTCCCACTGTGAATTATACAACTATGATTCACACCCCTGAAAACCCA
GTTATCCGTTACAAACGAAGATCAAAATGA

Clone variation with respect to NM_000786.3
1359 t=>c
>OriGene 5' read for NM_000786 unedited
GGATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGCTGCCAGCTT
CTCTCGTTCCGTCGATTGGGAGGAGCGGTGGCGACCTCGGCCTTCAGTGTTTCCGACGGA
GTGAATGGCGGCGGCGGCTGGGATGCTGCTGCTGGGCTTGCTGCAGGCGGGTGGGTCGGT
GCTGGGCCAGGCGATGGAGAAGGTGACAGGCGGCAACCTCTTGTCCATGCTGCTGATCGC
CTGCGCCTTCACCCTCAGCCTGGTCTACCTGATCCGTCTGGCCGCCGGCCACCTGGTCCA
GCTGCCCGCAGGGGTGAAAAGTCCTCCATACATTTTCTCCCCAATTCCATTCCTTGGGCA
TGCCATAGCATTTGGGAAAAGTCCAATTGAATTTCTAGAAAATGCATATGAGAAGTATGG
ACCTGTATTTAGTTTTACCATGGTAGGCAAGACATTTACTTACCTTCTGGGGAGTGATGC
TGCTGCACTGCTTTTTAATAGTAAAAATGAAGACCTGAATGCAGAAGATGTCTACAGTCG
CCTGACAACACCTGTGTTTGGGAAAGGGAGTTGCATACGATGTGCCTAATCCAGTTTTCT
TGGAGCAGAAGAAATGTTAAAAAGTGGCCTTACATAGCCCACTTTAACAGCATGTTTCTA
TTATTGAAAAAGAACAAGGAATCTTTGAGAGTTGGGGAAGAAAGTGAGAAAAAATGGGGT
TGAAGCTCTTCTGACTCATATTTTACAGCTAGCCATTGTTGCATGGAAAGGAATTCAAAG
TCACTCATGGAAAGGTACACAGCGATGCAATTGNNNGGGGGGGGGGTTTAACCTTGCACC
TGGCTTTACCCGGTTGCTGGCTGT
>OriGene 3' read for NM_000786 unedited
GTACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTCAAAAAAAATTTTATTCTGAAAATTACCAAAAATTTTGCCTTCCCA
TTTAAAGTTTAACATGAGTCTTCCAGGGTTTAAAAAAAACCTGTATTTTCCTTAAGGCAA
ATTTTTTGGGCTTCCCCTAGGGAAACCAACCGATGGGGTTTTTTTTCACCCTTCTCATTT
AGTTGGGCCCCGAGTTCCAATTGGAAATAAGTGGATTCCTAAACAAAAGGGGCTTTACAA
AAGGGGCCCATTTTTTTTCCTCCCAGAGGCCCTTGTTTCAAATTTTTTTAAACCCAAAGT
TCACTGATCTCACTTTTAAAAAAAAAAAAAGTTGGTTACCGGTTTTAATCAATTTGAGTG
GTACCAACCTTCCCTAATGGGATTCTAAAAAGGAACCAGGGAAGGCCAGGGGCGGGGGCT
CATGCCTGTAATCCCACCCCTTTGGGAGGCCAAGGGGGGGGGATCACAAGGTCAGGATTT
CAAAACCACCCTACCCAACTTAGGGAACCCCCTGTCTTTCCTAAAAATCCAAAAATTTAC
CCAGCCTTGGGGGCAGGGCCCTGTAATCCCAACTCCTTGGGAGGCTGAGGCAAAAAATTG
CTTGACCCCGGGAGGCAAAGGATGCATTGACCTGAAATCGCCCCACTGCCTCTCAGCCTG
GGCAACAGAGCGAGACTCCTTCTCAAAAAAAAAAAAAAAAGGGAAGCGGGGAACACCTGA
GCCAAAGCAAATTATCCTCTAGGACTTGACTTTGGACTCCACATAAGGGGACCTTGGAAA
ACTAAATCCTTTTTTCAGGAAAAAAATTGGTATTTTTTANAATTTGACCAAGAACTGGAC
CGCCTTTACATAATAATTACATTTTTTAGGATTCTATCAATTGGCN
Restriction Sites NotI-NotI     
ACCN NM_000786
Insert Size 3090 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000786.2, NP_000777.1
RefSeq Size 3381 bp
RefSeq ORF 1530 bp
Locus ID 1595
UniProt ID Q16850
Domains p450
Protein Families Druggable Genome, P450, Transmembrane
Protein Pathways Metabolic pathways, Steroid biosynthesis
Gene Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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