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CYP27A1 (NM_000784) Human Untagged Clone
CAT＃: SC119685
CYP27A1 (untagged)-Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein
CNY 3,960.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CP27; CTX; CYP27 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000784 edited
ATCGGCACGAGGCGAGCACAACCCATGGCTGCGCTGGGCTGCGCGAGGCTGAGGTGGGCG CTGCGAGGGGCCGGCCGTGGCCTCTGCCCCCACGGGGCCAGAGCCAAGGCCGCGATCCCT GCCGCCCTCCCCTCGGACAAGGCCACCGGAGCTCCCGGAGCCGGGCCTGGTGTCCGGCGG CGGCAACGGAGCTTAGAGGAGATTCCACGTCTAGGACAGCTGCGCTTCTTCTTTCAGCTG TTCGTTCAAGGCTATGCCCTGCAACTGCACCAGTTACAGGTGCTTTACAAGGCCAAGTAC GGTCCAATGTGGATGTCCTACTTAGGGCCTCAGATGCACGTGAACCTGGCCAGTGCCCCG CTCTTGGAGCAAGTGATGCGGCAAGAGGGCAAGTACCCAGTACGGAACGACATGGAGCTA TGGAAGGAGCACCGGGACCAGCACGACCTGACCTATGGGCCGTTCACCACGGAAGGACAC CACTGGTACCAGCTGCGCCAGGCTCTGAACCAGCGGTTGCTGAAGCCAGCGGAAGCAGCG CTCTATACGGATGCTTTCAATGAGGTGATTGATGACTTTATGACTCGACTGGACCAGCTG CGGGCAGAGAGTGCTTCGGGGAACCAGGTGTCGGACATGGTTCAACTCTTCTACTACTTT GCCTTGGAAGCTATTTGCTACATCCTGTTCGAGAAACGCATTGGCTGCCTGCAGCGATCC ATCCCCGAGGACACCGTGACCTTCGTCAGATCCATCGGGTTAATGTTCCAGAACTCACTC TATGCCACCTTCCTCCCCAAGTGGACTCGCCCCGTGCTGCCTTTCTGGAAGCGATACCTG GATGGTTGGAATGCCATCTTTTCCTTTGGGAAGAAGCTGATTGATGAGAAGCTCGAAGAT ATGGAGGCCCAACTGCAGGCAGCAGGGCCAGATGGCATCCAGGTGTCTGGCTACCTGCAC TTCTTACTGGCCAGTGGACAGCTCAGTCCTCGGGAGGCCATGGGCAGCCTGCCTGAGCTG CTCATGGCTGGAGTGGACACGACATCCAACACGCTGACATGGGCCCTGTACCACCTCTCA AAGGACCCTGAGATCCAGGAGGCCTTGCACGAGGAAGTGGTGGGTGTGGTGCCAGCCGGG CAAGTGCCCCAGCACAAGGACTTTGCCCACATGCCGTTGCTCAAAGCTGTGCTTAAGGAG ACTCTGCGTCTCTACCCTGTGGTCCCCACAAACTCCCGGATCATAGAAAAGGAAATTGAA GTTGATGGCTTCCTCTTCCCCAAGAACACCCAGTTTGTGTTCTGCCACTATGTGGTGTCC CGGGACCCCACTGCCTTCTCTGAGCCTGAAAGCTTCCAGCCCCACCGCTGGCTGAGAAAC AGCCAGCCTGCTACCCCCAGGATCCAGCACCCATTTGGCTCTGTGCCCTTTGGCTATGGG GTCCGGGCCTGCCTGGGCCGCAGGATTGCAGAGCTGGAGATGCAGCTACTCCTCGCAAGG CTGATCCAGAAGTACAAGGTGGTCCTGGCCCCGGAGACGGGGGAGTTGAAGAGTGTGGCC CGCATTGTCCTGGTTCCCAATAAGAAAGTGGGCCTGCAGTTCCTGCAGAGACAGTGCTGA GCTGAGTCTCCGCCTTGCTGGGGCTTGTCCTAGAGGCTCCAGCTCTGGCACAGTGGTTCC TGGCTGCTGCCATGTCTCAGATGAGGAGGGAGAGAAGGAGGCCGCCAGACTCGAGAGGTG GGAGGAACTCCTTGCACACACCCTGAGCTTTTGCCACTTCTATCATTTTTGAGCAACTCC CTCTCAGCTAAAAGGCCACCCCTTTATCGCATTGCTGTCCTTGGGTAGAATATAAAATAA AGGGACTTTTATTTTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAC >OriGene 5' read for NM_000784 unedited
GCGGCAAAAAACATCGGCACGAGGCGAGCACAACTTATGGCTGCGCTGGGCTGCGCGAGG CTGAGGTGGGCGCTGCGAGGGGCCGGCCGTGGCCTCTGCCCCCACGGGGCCAGAGCCAAG GCCGCGATCCCTGCCGCCCTCCCCTCGGACAAGGCCACCGGAGCTCCCGGAGCCGGGCCT GGTGTCCTGCTGCGGCAACGGAGCTTAGAGGATATTCCACGTCTAGGACAGCTGCGCTTC TTCTTTCAGCTGTTCGTTCAAGGCTATGCCCTGCAACTGCACCAGTTACAGGTGCTTTAC AAGGCCAAGTACGGTCCAATGTGGATGTCCTACTTAGGGCCTCAGATGCACGTGAACCTG GCCAGTGCCCCGCTCTTGGAGCAAGTGATGCGGCAAGAGGGCAAGTACCCAGTACGGAAC GACATGGAGCTATGGAAGGAGCACCGGGACCAGCACGACCTGACCTATGGGCCGTTCACC ACGGAAGGACACCACTGGTACCAGCTGCGCCAGGCTCTGAACCAGCGGTTGCTGAAGCCA GCGGAAGCAGCGCTCTATACGGATGCTTTCAATGAGGTGATTGATGACTTTATGACTCGA CTGGACCAGCTGCGGGCAGAGAGTGCTTCGGGGAACCAGGTGTCGGACATGGTTCAACTC TTCTACTACTTTGCCTTGGAAGCTATTTGCTACATCCTGTTCGAGAAACGCATTGGCTGC CTGCAGCGATCCATCCCCGAGGACACCGTGACCTTCGTCAGATCCATCGGGTTAATGTTC CAGAACTCACTCTATGCCACCTTCCTCCCCCAGTGGACTCGCCCCGTGCTGGCCTTTCTG GAAGCGATACCTTGGATGGTTGGATGCCAATCTTTTCCTTTGGAAGAAGCT >OriGene 3' read for NM_000784 unedited
TTTAGAGTCCTTTTTTTATTTCTACCCAGGGACAGCAATGCGATAAAGGGTGGCCTTTTA GCTGAGAGGGAGTTGCTCAAAAAGATAGAAGTGGCAAAAGCTCAGGGTGTGTGCAAGGAG TTCCTCCCACCTCTCGAGTCTGGCGGCCTCCTTCTCTCCCTCCTCATCTGAGACATGGCA GCAGCCAGGAACCACTGTGCCAGAGCTGGAGCCTCTAGGACAAGCCCCAGCAAGGCGGAG ACTCAGCTCAGCACTGTCTCTGCAGGAACTGCAGGCCCACTTTCTTATTGGGAACCAGGA CAATGCGGGCCACACTCTTCAACTCCCCCGTCTCCGGGGCCAGGACCACCTTGTACTTCT GGATCAGCCTTGCGAGGAGTAGCTGCATCTCCAGCTCTGCAATCCTGCGGCCCAGGCAGG CCCGGACCCCATAGCCAAAGGGCACAGAGCCAAATGGGTGCTGGATCCTGGGGGTAGCAG GCTGGCTGTTTCTCAGCCAGCGGTGGGGCTGGAAGCTTTCAGGCTCAGAGAAGGCAGTGG GGTCCCGGGACACCACATAGTGGCAGAACACAAACTGGGTGTTCTTGGGGAAGAGGAAGC CATCAACTTCAATTTCCTTTTCTATGATCCCGGCAGTTTGTGGGGACCACCAGGGTAGAG ACGCAGAGTCTCCCTTTAGCACAGNCTCTGAGCAACGGCATGGGGGCCAAGTCCCTTGGG CTGGGGGCACTTGCCCCGGCTGGCACCCCACCCACCACTTCCTCGTGCAAGGGCCTCCTG GATCTCAAGGGTCCTCTGAGAGGTGGGACAGGGCCCCATGTCACCCTGGTGGAGGTCGTG TCCCACTCCACCATGACCACTTCAGGCGGCCTGGCCATGGCCTCCCAGGACTGAACTGCC CACTGCCCCTAGAAGTGCAGGGAGCAAACACCTGGATGCCACTGCCCCTCTTGCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000784 |
| Insert Size | 2060 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000784.2, NP_000775.1 |
| RefSeq Size | 2059 bp |
| RefSeq ORF | 1596 bp |
| Locus ID | 1593 |
| UniProt ID | Q02318 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450 |
| Protein Pathways | Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222953 | CYP27A1 (Myc-DDK-tagged)-Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein |
CNY 3,952.00 |
|
| RC222953L1 | Lenti ORF clone of Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 6,352.00 |
|
| RC222953L2 | Lenti ORF clone of Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 6,352.00 |
|
| RC222953L3 | Lenti ORF clone of Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC222953L4 | Lenti ORF clone of Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 6,460.00 |
|
| RG222953 | CYP27A1 (tGFP-tagged) - Human cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein |
CNY 5,552.00 |
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