HRH1 (NM_000861) Human Untagged Clone

CAT#: SC119662

HRH1 (untagged)-Human histamine receptor H1 (HRH1), transcript variant 4



  "NM_000861" in other vectors (6)

CNY 3,656.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-HRH1 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms H1-R; H1R; HH1R; hisH1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_000861, the custom clone sequence may differ by one or more nucleotides


ATGAGCCTCCCCAATTCCTCCTGCCTCTTAGAAGACAAGATGTGTGAGGGCAACAAGACCACTATGGCCA
GCCCCCAGCTGATGCCCCTGGTGGTGGTCCTGAGCACTATCTGCTTGGTCACAGTAGGGCTCAACCTGCT
GGTGCTGTATGCCGTACGGAGTGAGCGGAAGCTCCACACTGTGGGGAACCTGTACATCGTCAGCCTCTCG
GTGGCGGACTTGATCGTGGGTGCCGTCGTCATGCCTATGAACATCCTCTACCTGCTCATGTCCAAGTGGT
CACTGGGCCGTCCTCTCTGCCTCTTTTGGCTTTCCATGGACTATGTGGCCAGCACAGCGTCCATTTTCAG
TGTCTTCATCCTGTGCATTGATCGCTACCGCTCTGTCCAGCAGCCCCTCAGGTACCTTAAGTATCGTACC
AAGACCCGAGCCTCGGCCACCATTCTGGGGGCCTGGTTTCTCTCTTTTCTGTGGGTTATTCCCATTCTAG
GCTGGAATCACTTCATGCAGCAGACCTCGGTGCGCCGAGAGGACAAGTGTGAGACAGACTTCTATGATGT
CACCTGGTTCAAGGTCATGACTGCCATCATCAACTTCTACCTGCCCACCTTGCTCATGCTCTGGTTCTAT
GCCAAGATCTACAAGGCCGTACGACAACACTGCCAGCACCGGGAGCTCATCAATAGGTCCCTCCCTTCCT
TCTCAGAAATTAAGCTGAGGCCAGAGAACCCCAAGGGGGATGCCAAGAAACCAGGGAAGGAGTCTCCCTG
GGAGGTTCTGAAAAGGAAGCCAAAAGATGCTGGTGGTGGATCTGTCTTGAAGTCACCATCCCAAACCCCC
AAGGAGATGAAATCCCCAGTTGTCTTCAGCCAAGAGGATGATAGAGAAGTAGACAAACTCTACTGCTTTC
CACTTGATATTGTGCACATGCAGGCTGCGGCAGAGGGGAGTAGCAGGGACTATGTAGCCGTCAACCGGAG
CCATGGCCAGCTCAAGACAGATGAGCAGGGCCTGAACACACATGGGGCCAGCGAGATATCAGAGGATCAG
ATGTTAGGTGATAGCCAATCCTTCTCTCGAACGGACTCAGATACCACCACAGAGACAGCACCAGGCAAAG
GCAAATTGAGGAGTGGGTCTAACACAGGCCTGGATTACATCAAGTTTACTTGGAAGAGGCTCCGCTCGCA
TTCAAGACAGTATGTATCTGGGTTGCACATGAACCGCGAAAGGAAGGCCGCCAAACAGTTGGGTTTTATC
ATGGCAGCCTTCATCCTCTGCTGGATCCCTTATTTCATCTTCTTCATGGTCATTGCCTTCTGCAAGAACT
GTTGCAATGAACATTTGCACATGTTCACCATCTGGCTGGGCTACATCAACTCCACACTGAACCCCCTCAT
CTACCCCTTGTGCAATGAGAACTTCAAGAAGACATTCAAGAGAATTCTGCATATTCGCTCCTAA


>OriGene 5' read for NM_000861 unedited
NGTGTTCAAATTTTGTAATACGACTCACTATAGGGCGGCCGCGCGGGNATGAGCCATAAC
TGGCGGCTGCTCTTGCGCCAATGAGCCTCCCCAATTCCTCCTGCCTCTTAGAAGACAAGA
TGTGTGAGGGCAACAAGACCACTATGGCCAGCCCCCAGCTGATGCCCCTGGTGGTGGTCC
TGAGCACTATCTGCTTGGTCACAGTAGGGCTCAACCTGCTGGTGCTGTATGCCGTACGGA
GTGAGCGGAAGCTCCACACTGTGGGGAACCTGTACATCGTCAGCCTCTCGGTGGCGGACT
TGATCGTGGGTGCCGTCGTCATGCCTATGAACATCCTCTACCTGCTCATGTCCAAGTGGT
CACTGGGCCGTCCTCTCTGCCTCTTTTGGCTTTCCATGGACTATGTGGCCAGCACAGCGT
CCATTTTCAGTGTCTTCATCCTGTGCATTGATCGCTACCGCTCTGTCCAGCAGCCCCTCA
GGTACCTTAAGTATCGTACCAAGACCCGAGCCTCGGCCACCATTCTGGGGGCCTGGTTTC
TCTCTTTTCTGTGGGTTATTCCCATTCTAGGCTGGAATCACTTCATGCAGCAGACCTCGG
TGCGCCGAGAGGACAAGTGTGAGACAGACTTCTATGATGTCACCTGGTTCAAGGTCATGA
CTGCCATCATCAACTTCTACCTGCCCACCTTGCTCATGCTCTGGTTCTATGCCAAGATCT
ACAAGGCCGTACGACAACACTGCCAGCACCGGGAGCTCATCAATAGGTCCCTCCCTTTCC
TTCTCAGAATTAAGCTGAGGCCAGAGAACCCCAAGGGGGATGCCAAGAAACCAGGNAAGG
AGTCTCCCTGGGAGGTTCTGAAAAGAAGCCCAAAGATGCTGTGGGGGAACTGTCTTGGC
>OriGene 3' read for NM_000861 unedited
AGCTATGNACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTGAACCCAGTTACAAAAAACAGGTCTGACTTTCTTGCAAAAATTCTGCTTCCTCCT
CAAAGTTCAATCTCTCTGCTGATCACCGCCATCTGCTGTTCTTCTATGGGGCCTAAAAAC
TTTCCAAACTACCAAGCCCCTAAAACTGGGGTTTGGATTCCAAAAAGCCCAGGTGCCTGC
CTGGCAACACACAGGCCTTCGTCCTCTATTTCCTTGTTGGACATCATAAGGATCATTTTG
TTGCATCCCCTCAAAGCCTCCCTTAGGAGCGAATATGCAGAATTCTCTTGAATGTCTTCT
TGAAGTTCTCATTGCACAAGGGGTAAATGAGGGGGTTCAGTGTGGAGTTGATGTAACCCA
ACCAGATGGTGAACATGTGCAAATGTTCATTGCAACAGTTCTTGCAGAAGGCAATGACCA
TGAAGAAGATGAAATAAGGGATCCAGCAGAGGATGAAGGCTGCCATGATAAAACCCAACT
GTTTGGCGGCCTTCCTTTCGCGGTTCATGTGCAACCCAGATACATACTGTCTTGAATGCG
AGCGGAGCCTCTTCCAAGTAAACTTGATGTAATCCAGGCCTGTGTTAGACCCACTCCTCA
ATTTGCCTTTGCCTGGTGCTGTCTCTGTGGTGGTATCTGAGTCCGTTCGAGAGAAGATGG
NCTATCACCTAACATCTGATCCTCTGAATCTCGCTGGCCCATGTGTTGTCAGGCCCTGCT
CATCTGTCTTGAGCTGGCCATGGCTTCCGGTGACGGCTACATAGTCCCTGCTACTNCCCT
CTGNCGCAGCCTGCATGTGCACAATATCAGTGGAAAGCANNNANAGNNTTGNCTACTTCT
CTATCACCTCTGGGCTGAAGACACTGGGGGATACATTCCTTNGGGGGGTTTGGGGAAGGG
GGGACTTCAAGACAGATCCACCACCAGCATCTTTGGGCCTT
Restriction Sites NotI-NotI     
ACCN NM_000861
Insert Size 1860 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000861.2, NP_000852.1
RefSeq Size 3870 bp
RefSeq ORF 1464 bp
Locus ID 3269
UniProt ID P35367
Domains 7tm_1
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
Gene Summary Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2015]
Transcript Variant: This variant (4), also known as H/I/K, differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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