United States
Germany
Japan
United Kingdom
China
IMPDH2 (NM_000884) Human Untagged Clone
CAT＃: SC119585
IMPDH2 (untagged)-Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2)
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMPD2; IMPDH-II |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119585 sequence for NM_000884 edited (data generated by NextGen Sequencing)
ATGGCCGACTACCTGATTAGTGGGGGCACGTCCTACGTGCCAGACGACGGACTCACAGCA CAGCAGCTCTTCAACTGCGGAGACGGCCTCACCTACAATGACTTTCTCATTCTCCCTGGG TACATCGACTTCACTGCAGACCAGGTGGACCTGACTTCTGCTCTGACCAAGAAAATCACT CTTAAGACCCCACTGGTTTCCTCTCCCATGGACACAGTCACAGAGGCTGGGATGGCCATA GCAATGGCGCTTACAGGCGGTATTGGCTTCATCCACCACAACTGTACACCTGAATTCCAG GCCAATGAAGTTCGGAAAGTGAAGAAATATGAACAGGGATTCATCACAGACCCTGTGGTC CTCAGCCCCAAGGATCGCGTGCGGGATGTTTTTGAGGCCAAGGCCCGGCATGGTTTCTGC GGTATCCCAATCACAGACACAGGCCGGATGGGGAGCCGCTTGGTGGGCATCATCTCCTCC AGGGACATTGATTTTCTCAAAGAGGAGGAACATGACTGTTTCTTGGAAGAGATAATGACA AAGAGGGAAGACTTGGTGGTAGCCCCTGCAGGCATCACACTGAAGGAGGCAAATGAAATT CTGCAGCGCAGCAAGAAGGGAAAGTTGCCCATTGTAAATGAAGATGATGAGCTTGTGGCC ATCATTGCCCGGACAGACCTGAAGAAGAATCGGGACTACCCACTAGCCTCCAAAGATGCC AAGAAACAGCTGCTGTGTGGGGCAGCCATTGGCACTCATGAGGATGACAAGTATAGGCTG GACTTGCTCGCCCAGGCTGGTGTGGATGTAGTGGTTTTGGACTCTTCCCAGGGAAATTCC ATCTTCCAGATCAATATGATCAAGTACATCAAAGACAAATACCCTAATCTCCAAGTCATT GGAGGCAATGTGGTCACTGCTGCCCAGGCCAAGAACCTCATTGATGCAGGTGTGGATGCC CTGCGGGTGGGCATGGGAAGTGGCTCCATCTGCATTACGCAGGAAGTGCTGGCCTGTGGG CGGCCCCAAGCAACAGCAGTGTACAAGGTGTCAGAGTATGCACGGCGCTTTGGTGTTCCG GTCATTGCTGATGGAGGAATCCAAAATGTGGGTCATATTGCGAAAGCCTTGGCCCTTGGG GCCTCCACAGTCATGATGGGCTCTCTCCTGGCTGCCACCACTGAGGCCCCTGGTGAATAC TTCTTTTCCGATGGGATCCGGCTAAAGAAATATCGCGGTATGGGTTCTCTCGATGCCATG GACAAGCACCTCAGCAGCCAGAACAGATATTTCAGTGAAGCTGACAAAATCAAAGTGGCC CAGGGAGTGTCTGGTGCTGTGCAGGACAAAGGGTCAATCCACAAATTTGTCCCTTACCTG ATTGCTGGCATCCAACACTCATGCCAGGACATTGGTGCCAAGAGCTTGACCCAAGTCCGA GCCATGATGTACTCTGGGGAGCTTAAGTTTGAGAAGAGAACGTCCTCAGCCCAGGTGGAA GGTGGCGTCCATAGCCTCCATTCGTATGAGAAGCGGCTTTTCTGA Clone variation with respect to NM_000884.2 >OriGene 5' read for NM_000884 unedited
CAAGGTTTTGTAAATCCCNACCTCTGAGAGGGCGGCACGAGACTTCGGCACGAGGGTCTC TGCGGCGCGGTCCTCGGAGACACGCGGCGGTGTCCTGTGTTGGCCATGGCCGACTACCTG ATTAGTGGGGGCACGTCCTACGTGCCAGACGACGGACTCACAGCACAGCAGCTCTTCAAC TGCGGAGACGGCCTCACCTACAATGACTTTCTCATTCTTTCTGGGTACATCGACTTCACT GCAGACCAGGTGGACCTGACTTCTGCTCTGACCAAGAAAATCACTCTTAAGACCCCACTG GTTTCCTCTCCCATGGACACAGTCACAGAGGCTGGGATGGCCATAGCAATGGCGCTTACA GGCGGTATTGGCTTCATCCACCACAACTGTACACCTGAATTCCAGGCCAATGAAGTTCGG AAAGTGAAGAAATATGAACAGGGATTCATCACAGACCCTGTGGTCCTCAGCCCCAAGGAT CGCGTGCGGGATGTTTTTGAGGCCAAGGCCCGGCATGGTTTCTGCGGTATCCCAATCACA GACACAGGCCGGATGGGGAGCCGCTTGGTGGGCATCATCTCCTCCAGGGACATTGATTTT CTCAAAGAGGAGGAACATGACTGTTTCTTGGAAGAGATAATGACAAAGATGGAAGACTTG GTGGTAGCCCCTGCAGGCATCACACTGAAGGATGCAAATGATATTCTGCAGCGCAGCAAG AAAGGGAAGTTGCCCATTGGTAATGAAGATGATGAGCTTGTGGCCATCATTGCCCCGACA GACCTGGAGAAAATCGGGACTACCCACTAGCCTCCAAAGATGCCAAGAACAGCTGCTGTG TGGGGCAGCCATTGGCCCTCATGAAGATGACAAGTATAGGCTTGGACTTGCTCGCCCCAG GCCGTTGTTGATAGTATGGTTTTGGACTCTCCCCAGGG >OriGene 3' read for NM_000884 unedited
NNNNAACACTCTGGACCCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTCT TTCTAAACTTTTATTGAAAAAAAAACCGAGGAGGTGTGCTGGATCCCTTTTCAGAAAAGC CGCTTCTCATACGAATGGAGGCTATGGACGCCACCTTCCACCTGGGCTGAGGACGTTCTC TTCTCAAACTTAAGCTCCCCAGAGTACATCATGGCTCGGACTTGGGTCAAGCTCTTGGCA CCAATGTCCTGGCATGAGTGTTGGATGCCAGCAATCAGGTAAGGGACAAATTTGTGGATT GACCCTTTGTCCTGCACAGCACCAGACACTCCCTGGGCCACTTTGATTTTGTCAGCTTCA CTGAAATATCTGTTCTGGCTGCTGAGGTGCTTGTCCATGGCATCGAGAGAACCCATACCG CGATATTTCTTTAGCCGGATCCCATCGGAAAAGAAGTATTCACCAGGGGCCTCAGTGGTG GCAGCCAGGAGAGAGCCCATCATGACTGTGGAGGCCCCAAGGGCCAAGGCTTTCGCAATA TGACCCACATTTTGGATTCCTCCATCAGCAATGACCGGAACACCAAAGCGCCGTGCATAC TCTGACACCTTGTACACTGCTGTTGCTTGGGGCCGCCCACAGGCCAGCACTTCCTGCGTA ATGCAGATGGAGCCACTTCCCATGCCCACCCGCAGGGCATCCACACCTGCATCAATGAGG TTCTTGGCCTGNGCAGCAGTGACCACATTGCCTCCAATGACTTGGAGATTAGGGTATTTG TCTTTGATGTACTTGATCATATTGATCTGGAAGATGGAAATTCCCTGGGAAGAGTNNCAA ACCACTACATCCACACAGCCTGGGCGAGCAAGTCAGCCTATACTGTCATCTNATGAGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000884 |
| Insert Size | 1570 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000884.2, NP_000875.2 |
| RefSeq Size | 1712 bp |
| RefSeq ORF | 1545 bp |
| Locus ID | 3615 |
| UniProt ID | P12268 |
| Domains | CBS, IMPDH |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
| Gene Summary | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202977 | IMPDH2 (Myc-DDK-tagged)-Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2) |
CNY 3,832.00 |
|
| RC202977L1 | Lenti ORF clone of Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202977L2 | Lenti ORF clone of Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), mGFP tagged |
CNY 5,890.00 |
|
| RC202977L3 | Lenti ORF clone of Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202977L4 | Lenti ORF clone of Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), mGFP tagged |
CNY 5,890.00 |
|
| RG202977 | IMPDH2 (tGFP-tagged) - Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2) |
CNY 4,370.00 |
