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alpha Actinin (ACTN1) (NM_001102) Human Untagged Clone
CAT＃: SC119433
ACTN1 (untagged)-Human actinin, alpha 1 (ACTN1), transcript variant 2
CNY 6,544.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BDPLT15 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119433 sequence for NM_001102 edited (data generated by NextGen Sequencing)
ATGGACCATTATGATTCTCAGCAAACCAACGATTACATGCAGCCAGAAGAGGACTGGGAC CGGGACCTGCTCCTGGACCCGGCCTGGGAGAAGCAGCAGAGAAAGACATTCACGGCATGG TGTAACTCCCACCTCCGGAAGGCGGGGACACAGATCGAGAACATCGAAGAGGACTTCCGG GATGGCCTGAAGCTCATGCTGCTGCTGGAGGTCATCTCAGGTGAACGCTTGGCCAAGCCA GAGCGAGGCAAGATGAGAGTGCACAAGATCTCCAACGTCAACAAGGCCCTGGATTTCATA GCCAGCAAAGGCGTCAAACTGGTGTCCATCGGAGCCGAAGAAATCGTGGATGGGAATGTG AAGATGACCCTGGGCATGATCTGGACCATCATCCTGCGCTTTGCCATCCAGGACATCTCC GTGGAAGAGACTTCAGCCAAGGAAGGGCTGCTCCTGTGGTGTCAGAGAAAGACAGCCCCT TACAAAAATGTCAACATCCAGAACTTCCACATAAGCTGGAAGGATGGCCTCGGCTTCTGT GCTTTGATCCACCGACACCGGCCCGAGCTGATTGACTACGGGAAGCTGCGGAAGGATGAT CCACTCACAAATCTGAATACGGCTTTTGACGTGGCAGAGAAGTACCTGGACATCCCCAAG ATGCTGGATGCCGAAGACATCGTTGGAACTGCCCGACCGGATGAGAAAGCCATCATGACT TACGTGTCTAGCTTCTACCACGCCTTCTCTGGAGCCCAGAAGGCGGAGACAGCAGCCAAT CGCATCTGCAAGGTGTTGGCCGTCAACCAGGAGAACGAGCAGCTTATGGAAGACTACGAG AAGCTGGCCAGTGATCTGTTGGAGTGGATCCGCCGCACAATCCCGTGGCTGGAGAACCGG GTGCCCGAGAACACCATGCATGCCATGCAACAGAAGCTGGAGGACTTCCGGGACTACCGG CGCCTGCACAAGCCGCCCAAGGTGCAGGAGAAGTGCCAGCTGGAGATCAACTTCAACACG CTGCAGACCAAGCTGCGGCTCAGCAACCGGCCTGCCTTCATGCCCTCTGAGGGCAGGATG GTCTCGGACATCAACAATGCCTGGGGCTGCCTGGAGCAGGTGGAGAAGGGCTATGAGGAG TGGTTGCTGAATGAGATCCGGAGGCTGGAGCGACTGGACCACCTGGCAGAGAAGTTCCGG CAGAAGGCCTCCATCCACGAGGCCTGGACTGACGGCAAAGAGGCCATGCTGCGACAGAAG GACTATGAGACCGCCACCCTCTCGGAGATCAAGGCCTTGCTCAAGAAGCATGAGGCCTTC GAGAGTGACCTGGCTGCCCACCAGGACCGTGTGGAGCAGATTGCCGCCATCGCACAGGAG CTCAATGAGCTGGACTATTATGACTCACCCAGTGTCAACGCCCGTTGCCAAAAGATCTGT GACCAGTGGGACAATCTGGGGGCCCTAACTCAGAAGCGAAGGGAAGCTCTGGAGCGGACC GAGAAACTGCTGGAGACCATTGACCAGCTGTACTTGGAGTATGCCAAGCGGGCTGCACCC TTCAACAACTGGATGGAGGGGGCCATGGAGGACCTGCAGGACACCTTCATTGTGCACACC ATTGAGGAGATCCAGGGACTGACCACAGCCCATGAGCAGTTCAAGGCCACCCTCCCTGAT GCCGACAAGGAGCGCCTGGCCATCCTGGGCATCCACAATGAGGTGTCCAAGATTGTCCAG ACCTACCACGTCAATATGGCGGGCACCAACCCCTACACAACCATCACGCCTCAGGAGATC AATGGCAAATGGGACCACGTGCGGCAGCTGGTGCCTCGGAGGGACCAAGCTCTGACGGAG GAGCATGCCCGACAGCAGCACAATGAGAGGCTACGCAAGCAGTTTGGAGCCCAGGCCAAT GTCATCGGGCCCTGGATCCAGACCAAGATGGAGGAGATCGGGAGGATCTCCATTGAGATG CATGGGACCCTGGAGGACCAGCTCAGCCACCTGCGGCAGTATGAGAAGAGCATCGTCAAC TACAAGCCAAAGATTGATCAGCTGGAGGGCGACCACCAGCTCATCCAGGAGGCGCTCATC TTCGACAACAAGCACACCAACTACACCATGGAGCACATCCGTGTGGGCTGGGAGCAGCTG CTCACCACCATCGCCAGGACCATCAATGAGGTAGAGAACCAGATCCTGACCCGGGATGCC AAGGGCATCAGCCAGGAGCAGATGAATGAGTTCCGGGCCTCCTTCAACCACTTTGACCGG GATCACTCCGGCACACTGGGTCCCGAGGAGTTCAAAGCCTGCCTCATCAGCTTGGGTTAT GATATTGGCAACGACCCCCAGGGAGAAGCAGAATTTGCCCGCATCATGAGCATTGTGGAC CCCAACCGCCTGGGGGTAGTGACATTCCAGGCCTTCATTGACTTCATGTCCCGCGAGACA GCCGACACAGATACAGCAGACCAAGTCATGGCTTCCTTCAAGATCCTGGCTGGGGACAAG AACTACATTACCATGGACGAGCTGCGCCGCGAGCTGCCACCCGACCAGGCTGAGTACTGC ATCGCGCGGATGGCCCCCTACACCGGCCCCGACTCCGTGCCAGGTGCTCTGGACTACATG TCCTTCTCCACGGCGCTGTACGGCGAGAGTGACCTCTAA Clone variation with respect to NM_001102.3 1297 c=>t >OriGene 5' read for NM_001102 unedited
NGGTTTAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCTAGTTC AGTGTGCGTGGAGATTAGGTCCAAGCGCCCGCCCAGAGGCGGCAGTCCGCGAGCCCAGCC GCCGCTGTCGCCGCCAGTAGCAGCCTTCGCCAGCAGCGCCGCGGCGGAACCGGGCGCAGG GGAGCGAGCCCGGCCCCGCCAGCCCAGCCCAGCCCAGCCCAGCCCTACTCCCTCCCCACG CCAGGGCAGCAGCCGTTGCTCAGAGAGAAGGTGGAGGAAGAAATCCAGACCCTAGCACGC GCGCACCATCATGGACCATTATGATTCTCAGCAAACCAACGATTACATGCAGCCAGAAGA GGACTGGGACCGGGACCTGCTCCTGGACCCGGCCTGGGAGAAGCAGCAGAGAAAGACATT CACGGCATGGTGTAACTCCCACCTCCGGAAGGCGGGGACACAGATCGAGAACATCGAAGA GGACTTCCGGGATGGCCTGAAGCTCATGCTGCTGCTGGAGGTCATCTCAGGTGAACGCTT GGCCAAGCCAGAGCGAGGCAAGATGAGAGTGCACAAGATCTCCAACGTCAACAAGGCCCT GGATTTCATAGCCAGCAAAGGCGTCAAACTGGTGTCCATCGGAGCCCGAAGAAATCGTGG ATTGGGGAATGTGAAGATGACCCTGTGCATGACCTGGCCATCATCCTGCGCTTTGGCATC CAGGACATCTCCGTGGAAGAGACTTCAGCCAAGGAAGGCCTGCTCCTGTGGTGTCAGAGC AAGACAGCCCCTTACAAAATGTAAACCTTCAGAACTCTCACATAGCTGGAAGGATGGCCT CGCTTCTGTGCTTTGATCCACCGACACCGGCCCCACCTGTATTGACTCGGTAAGCTGCGG AAG >OriGene 3' read for NM_001102 unedited
CGCGGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTCTAGGAGTGTGGTTTT TTTAATACCATCTGTGCCAAGCAATATCAAAGTTGTCCATACTCTCCAAGTTTGTCCTAT TTTTAATAGACAATATTAAAAATTTTTTAAGTGTGTGCTGATAAAGAGACTAGTCACACC TCTGAGGGGATTTAAAAATGAGAAGCCACATAAATTCTCTTCCTTAAAAAACAGCCATTT CAAAAGATTTTCTTTAATATCATAAAATATTTTCATGGACAAGTGAGCTAGCAAACACAC ATGCACCAATGTGCCTTTTGACAAGAGTACCCCCTACCCCGACTCCCACACCAAAATGGA CATGAGATTGGAGAAATGAATACAGCAGATGGAACAGATAGAAGAAAAAAAATCAGTAAA AAGGATGGAATATAACTTTGTGCTTGGTTATTTTCCTATGTCGCAACAAAACAAGACATT TCGGTGCAAATAGTTAATCTTTCCTCTTTTTTTCCATTTGTCTGGTGGAGAAAAAATACT TTTTCTATAATAAAATATGTAGTTTTTTGGTTTTTAACGTAACTTTTTTTTTCTTTTTTG CAGAAAATAATTTTGTAAACTGTCACTTCGCGGGCAGGGAGGATCGATGCCACGTGGGCC CCAGCTCACCCGGGTGGAGGCTGGGAGCTGAAACCGAACCCAGCAGGATATGGGCGACGG CGGATGTGCAAGGCATGGCACGGCGCACAATACNAGGGCGGCCGGGCGGGGTGGATTAAA GGTCACTCTCGCCGTACAGCGCCGTGGAGATGACATGTANTCCATAACACCCTGCACGGA GTCGGGGCCGTGTTAGGGGCCCATCCCGCGCAGCAGTACTCANCCTGTTTCGGTGGCACC TCGCGGCGCAACTCGNCCATGGTAATGTAANTCCTTGCCCCCAGCAAGATCTTGTAGGNA AGCATGACTGTGGCTGCTGTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001102 |
| Insert Size | 3520 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001102.2, NP_001093.1 |
| RefSeq Size | 3398 bp |
| RefSeq ORF | 2679 bp |
| Locus ID | 87 |
| UniProt ID | P12814 |
| Domains | CH, spectrin, EFh |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Systemic lupus erythematosus, Tight junction |
| Gene Summary | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204924 | ACTN1 (Myc-DDK-tagged)-Human actinin, alpha 1 (ACTN1), transcript variant 2 |
CNY 6,536.00 |
|
| RC204924L1 | Lenti ORF clone of Human actinin, alpha 1 (ACTN1), transcript variant 2, Myc-DDK-tagged |
CNY 8,936.00 |
|
| RC204924L2 | Lenti ORF clone of Human actinin, alpha 1 (ACTN1), transcript variant 2, mGFP tagged |
CNY 9,030.00 |
|
| RC204924L3 | Lenti ORF clone of Human actinin, alpha 1 (ACTN1), transcript variant 2, Myc-DDK-tagged |
CNY 8,936.00 |
|
| RC204924L4 | Lenti ORF clone of Human actinin, alpha 1 (ACTN1), transcript variant 2, mGFP tagged |
CNY 8,936.00 |
|
| RG204924 | ACTN1 (tGFP-tagged) - Human actinin, alpha 1 (ACTN1), transcript variant 2 |
CNY 8,136.00 |
|
| SC320917 | ACTN1 (untagged)-Human actinin, alpha 1 (ACTN1), transcript variant 2 |
CNY 6,544.00 |
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