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Amino terminal enhancer of split (AES) (NM_001130) Human Untagged Clone
CAT＃: SC119415
AES (untagged)-Human amino-terminal enhancer of split (AES), transcript variant 2
CNY 2,400.00
CNY 3,990.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AES; AES-1; AES-2; ESP1; GRG; Grg-5; GRG5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119415 sequence for NM_001130 edited (data generated by NextGen Sequencing)
ATGATGTTTCCACAAAGCAGGCATTCGGGCTCCTCGCACCTACCCCAGCAACTCAAATTC ACCACCTCGGACTCCTGCGACCGCATCAAAGACGAATTTCAGCTACTGCAAGCTCAGTAC CACAGCCTCAAGCTCGAATGTGACAAGTTGGCCAGTGAGAAGTCAGAGATGCAGCGTCAC TATGTGATGTACTACGAGATGTCCTACGGCTTGAACATCGAGATGCACAAACAGGCTGAG ATCGTCAAAAGGCTGAACGGGATTTGTGCCCAGGTCCTGCCCTACCTCTCCCAAGAGCAC CAGCAGCAGGTCTTGGGAGCCATTGAGAGGGCCAAGCAGGTCACCGCTCCCGAGCTGAAC TCTATCATCCGACAGCAGCTCCAAGCCCACCAGCTGTCCCAGCTGCAGGCCCTGGCCCTG CCCTTGACCCCACTACCCGTGGGGCTGCAGCCGCCTTCGCTGCCGGCGGTCAGCGCAGGC ACCGGCCTCCTCTCGCTGTCCGCGCTGGGTTCCCAGGCCCACCTCTCCAAGGAAGACAAG AACGGGCACGATGGTGACACCCACCAGGAGGATGATGGCGAGAAGTCGGATTAG Clone variation with respect to NM_001130.5 >OriGene 5' read for NM_001130 unedited
TAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGCGATCGGCGCCGGGACAA AGGCGCGGCCGCCCGGCGCCCCCAGCAGCCCGAGCCGGGGCGCACAGCCGGGGCGCAGCC CGCGCCCCCCGCCGCGATTGACATGATGTTTCCACAAAGCAGGCATTCGGGCTCCTCGCA CCTACCCCAGCAACTCAAATTCACCACCTCGGACTCCTGCGACCGCATCAAAGACGAATT TCAGCTACTGCAAGCTCAGTACCACAGCCTCAAGCTCGAATGTGACAAGTTGGCCAGTGA GAAGTCAGAGATGCAGCGTCACTATGTGATGTACTACGAGATGTCCTACGGCTTGAACAT CGAGATGCACAAACAGGCTGAGATCGTCAAAAGGCTGAACGGGATTTGTGCCCAGGTCCT GCCCTACCTCTCCCAAGAGCACCAGCAGCAGGTCTTGGGAGCCATTGAGAGGGCCAAGCA GGTCACCGCTCCCGAGCTGAACTCTATCATCCGACAGCAGCTCCAAGCCCACCAGCTGTC CCAGCTGCAGGCCCTGGCCCTGCCCTTGACCCCACTACCCGTGGGGCTGCAGCCGCCTTC GCTGCCGGCGGTCAGCGCAGGCACCGGCCTNCTCTCGCTGTCCGCGCTGGGTTCCCAGGC CCACCTCTCCAGGGAGACAGAACGGGCACGATGGTGACACCCACCAGGAGGATGATGGCG AGAAAGTCGATTANCAAGGNGGCCGGACGGNGAGGGTTGGAGGGNGGACCAGAGGGANAC AGAGGCACNGAGAGAAAAGGATGTTTATCACAAGACACAGCGGAGCTCGGGGATGGNCTA ACTCCATAGTATTTATGGTGGCCGNNCGCGNNGGCCCCAGCCAGCTTGCAAGCCCACTNT AGCTTTNTTNNCTACCCCATACGGNNNTTCTTCCTCCTCCCNTGCAGNCTGGNTATGTGG ATACCTGCCCTGACTGGTTGAGCAAGCTAGG >OriGene 3' read for NM_001130 unedited
CGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAAACT TCTCACATCTTTATTGGAAAGGCACAGCTAAGCCCACCCTTGATACAGCATTTTCCACTT CTCTCTGTAGAGATCAGACGATTGAACACGAGATAAGCTGACTATATACAGACACAGGTG TGGGTGTTGCTTTTTTTTAAAAACACTTTTGGCTTTTTTTTTTTTTAATATCCCCTTTCT TAAAAGACAAGCTAGTATACTGGAAAAAGAAAAAAATAATAATAAAATAAAAACCAAGAC AACTTTAGTACCCTCATCTTTATTTGGGAAGGGGAGGGGGAATCCTGGGTCGCCCACCCT TACCCTGGTCCTCCCAGCTCAGCTAAGCTCGTCCCTCGTGCCCCCCCTTTTGTGGGCGAT GGGAAAGGACCAGGTGGGCGTGGAGGTGTCTGGAACTAACAAAGGTGGTGAGTGGGGCAA GTGGAGGTGGGAGCATACCTGGGACCCGGGGTCGGGGGAGACTCGGGGTGCCCAGGACGG GAAAGGGGCAGCTAGCATTGCGTGCATGCAGTACCAGGGTGAGAGGGCTGTGGCCCAGGC AGACTGTCGGTTACACATGTTCAAAACGGGGGAAGGGCCGGGGCTGCTGCGCTTCGCGAG GTCTTGCTCCCTTGGGACCTGGTCTCCCATCTGACCCTCCAGGCCTTAGCTTGCCTCACA CGTCAGGGCAGGTATCCACCTAACGGNCTGCAGGGGAGGAGGAGGGAANCCCGGATGGGG TANGAAAAAGCTANAGTGGCCTGCAACTGGCTGGGGCCCCGCCGCGGCCCATAATACTTG GGATTATCCATCCGACTCGCTGGTCTGGCTAAATTCTCTTCGCGCCCGGGTCCCCCTTGC CCCCTTCAACTCCGGTCGGCCCTGTATACGATTCGCTATCCCTGGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001130 |
| Insert Size | 1650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001130.5, NP_001121.2 |
| RefSeq Size | 1687 bp |
| RefSeq ORF | 594 bp |
| Locus ID | 166 |
| UniProt ID | Q08117 |
| Domains | TLE_N |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter and has a distinct N-terminus compared to isoform a. |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Membrane insertion and secretion of the Engrailed-2 (EN2) transcription factor by prostate cancer cells may induce antiviral activity in the stroma
,null,
Scientific Reports
,PubMed ID 30914795
[TLE5]
|
|
Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 26858406
[TLE5]
|
|
The Use of Human Wharton's Jelly Cells for Cochlear Tissue Engineering.
,null,
Methods in molecular biology (Clifton, N.J.)
,PubMed ID 27259936
[TLE5]
|
|
Identification of GABAC Receptor Protein Homeostasis Network Components from Three Tandem Mass Spectrometry Proteomics Approaches
,null,
Journal of proteome research
,PubMed ID 24079818
[TLE5]
|
|
Interaction of G-Protein ?? Complex with Chromatin Modulates GPCR-Dependent Gene Regulation
,null,
PLoS ONE
,PubMed ID 23326349
[TLE5]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212475 | AES (Myc-DDK-tagged)-Human amino-terminal enhancer of split (AES), transcript variant 2 |
CNY 2,400.00 |
|
| RC212475L3 | Lenti ORF clone of Human amino-terminal enhancer of split (AES), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212475L4 | Lenti ORF clone of Human amino-terminal enhancer of split (AES), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG212475 | AES (tGFP-tagged) - Human amino-terminal enhancer of split (AES), transcript variant 2 |
CNY 4,000.00 |
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